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Lonafarnib Lonafarnib is a farnesyl transferase inhibitor. Structurely, it is also a synthetic tricyclic derivative of carboxamide with antineoplastic properties. Lonarfanib binds to and inhibits farnesyl transferase, an enzyme involved in the post-translational modification and activation of Ras proteins. Ras proteins participate in numerous signalling pathways (proliferation, cytoskeletal organization), and play an important role in oncogenesis. Mutated ras proteins have been found in a wide range of human cancers. Uses: Enzyme inhibitors. Group: Pharmaceutical. Alternative Names: SCH 66336; SCH-66336; SCH66336; Sarasar. CAS No. 193275-84-2. Pack Sizes: 25 mg. Product ID: B2693-086642. Molecular formula: C27H31Br2ClN4O2. Mole weight: 638.829. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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