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| Product | Description | |
|---|---|---|
| Acaterin | Acarbose is an acyl-CoA isolated from Pseudomonas species. A92. In the presence of oxidized low-density lipoprotein in macrophages J744, the synthesis of cholesterol enzymes is inhibited, with an IC50 of 45 μmol/L, and the IC50 for inhibiting ACAT in rat liver microsomes is 120 μmol/L. Inhibition of ACAT is non-competitive Sexual. Group: Pharmaceutical. CAS No. 144398-20-9. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-00539. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Berberine hydrochloride | Berberine hydrochloride is an isoqinoline alkaloid and acts as a COX-2 inhibitor that exhibits chemopreventive activity against colon tumor formation. Study in humans and hamsters shows that berberine reduces total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides. It also inhibits c-Jun and suppresses inflammation and cancers. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 633-65-8. Pack Sizes: 250 g. Product ID: B0084-073975. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Blumeatin | Blumeatin is found in tea and is extracted from the herbs of Blumea balsamifera. It can enhance adipocyte differentiation by increasing triglyceride levels in 3T3L1 cells. It also can increase the accumulation of lipid droplets and induce upregulation of the expression of the adipocyte-specific genes GLUT4 and aP2. It inhibits the increase of liver triglyceride and serum alanine aminotransferase, and increases serum beta-lipoprotein, liver glycogen and triglyceride content in CCl4-intoxicated rats, thus shorten the pentobarbital sleeping time in CCl4-intoxicated mice. It shows free radical scavenging activity, xanthine oxidase (XO) inhibitory activity and antioxidant properties. It can protect liver against injury induced by CCl4 and TAA. Group: Pharmaceutical. CAS No. 118024-26-3. Pack Sizes: 10 mg. Product ID: B1370-267733. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Colesevelam hydrochloride | Colesevelam is a bile acid sequestrant that helps reduce elevated low-density lipoprotein cholesterol (LDL-C) in patients with primary hyperlipidemia, and also improve blood glucose balance in adults with type 2 diabetes mellitus. Group: Pharmaceutical. CAS No. 182815-44-7. Pack Sizes: 500 mg. Product ID: B0046-086232. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Darapladib | Darapladib (SB-480848) is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.25 nM. Group: Pharmaceutical. CAS No. 356057-34-6. Pack Sizes: 10 mg. Product ID: B0084-111850. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Dextrothyroxine sodium | Dextrothyroxine is an antihyperlipidemic. It stimulates the formation of low-density lipoprotein (LDL) and increases the catabolism of LDL thereby leading to increased excretion of cholesterol and bile acids via the biliary route. Group: Pharmaceutical. CAS No. 137-53-1. Pack Sizes: 100 mg. Product ID: B2692-068737. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Evacetrapib | Evacetrapib (LY2484595) is a drug that inhibits cholesterylester transfer protein, which transfers and thereby increases high-density lipoprotein and lowers low-density lipoprotein. Group: Pharmaceutical. CAS No. 1186486-62-3. Pack Sizes: 10 mg. Product ID: B0084-457317. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lathosterol | Lathosterol is an intermediate in the biosynthesis of cholesterol. Lathosterol in serum is carried on lipoproteins and is indicative of the rate of cholesterol synthesis. It acts as a marker of synthesis of cholesterol and is not affected by dietary consumption of cholesterol. Group: Pharmaceutical. CAS No. 80-99-9. Pack Sizes: 1 g. Product ID: B1370-033919. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Pitavastatin Impurity 8 | An impurity of Pitavastatin which lowers both total cholesterol and low density lipoprotein cholesterol in animals and humans. Group: Pharmaceutical. CAS No. 1044518-75-3. Pack Sizes: 25 mg. Product ID: B2694-478922. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rilapladib | Rilapladib is the third genomics-derived small molecule drug as a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor which is an enzyme associated with the formation of atherosclerotic plaques. Uses: 1-alkyl-2-acetylglycerophosphocholine esterase inhibitors. Group: Pharmaceutical. CAS No. 412950-08-4. Pack Sizes: 50 mg. Product ID: B1370-068407. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Silybin A | Silymarin, isolated from the herb of Silybum marianum (L.) Gaertn, is an antioxidant or free radical scavenger. Silymarin and Prunella vulgaris improve antioxidant status in blood and liver, and positively affect plasma lipoprotein profile in an experimental model of dietary induced hypertriglyceridemia. Both in vitro and animal research suggest that Silymarin has hepatoprotective (antihepatotoxic) properties that protect liver cells against toxins. Silymarin has also demonstrated in vitro anti-cancer effects against human prostate adenocarcinoma cells, estrogen-dependent human breast carcinoma cells, human ectocervical carcinoma cells, human colon cancer cells, and both small and nonsmall human lung carcinoma cells. Silymarin treatment in type II diabetic patients for 4 months has a beneficial effect on improving the glycemic profile. Treatment with silymarin may reduce the lipoperoxidation of cell membranes and insulin resistance, significantly decreasing endogenous insulin overproduction and the need for exogenous insulin administration. Silybin is a natural compound also can be used in cosmetics material. Uses: Protective agents. Group: Pharmaceutical. CAS No. 22888-70-6. Pack Sizes: 100 g. Product ID: NP1920. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| T0901317 | T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively. T0901317 induces apoptosis and inhibits the development of atherosclerosis in low-density lipoprotein (LDL) receptor-deficient mice. Group: Pharmaceutical. CAS No. 293754-55-9. Pack Sizes: 300 mg. Product ID: B0084-369166. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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