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| Product | Description | |
|---|---|---|
| Lipid 5 | Lipid 5 is a cationic amino lipid. LNPs incorporating Lipid 5 (from Sabnis et al.) demonstrated potent delivery of mRNA in primates but also were rapidly cleared from the body resulting in low toxicity. Group: Pharmaceutical. Alternative Names: Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)-8-oxooctyl)amino)octanoate. CAS No. 2089251-33-0. Pack Sizes: 100 mg. Product ID: B1370-376226. Molecular formula: C44H87NO5. Mole weight: 710.18. Custom synthesis is available. Send your inquiries for more information. |  London |
| Lipid ALC-0159 | ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG chain mass of about 2 kilodaltons (corresponding to about 45-46 ethylene oxide units per molecule of N,N-dimyristyl hydroxyacetamide). Group: Pharmaceutical. Alternative Names: 2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide; ALC-0159; mPEG-N,N-Ditetradecylacetamide. CAS No. 1849616-42-7. Pack Sizes: 500 mg. Product ID: B2699-051402. Custom synthesis is available. Send your inquiries for more information. | London |
| 1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt) | 1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt) is a liposome formulation for cationic lipid DOTAP. DOTAP can be used for the efficiency of DNA transfection, including yeast artificial chromosomes (YAC) transfection to eukaryotic cells used in transient or stable gene expression, and also suitable for efficient will other negatively charged molecules, such as RNA, oligonucleotides, and glutamic acid, the ribosome protein (RNP) complex, and protein, transferred to the study sample of mammalian cells. Group: Pharmaceutical. Alternative Names: DOTAP Transfection Reagent; DOTAP-MS; N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium methyl sulfate; DOTAP methosulfate; 18:1 TAP (DOTAP, MS Salt); n-(2,3-dioleoyloxy-1-propyl) trimethylammonium methyl sulfate. CAS No. 144189-73-1. Pack Sizes: 500 mg. Product ID: BAT-006359. Molecular formula: C43H83NO8S. Mole weight: 774.19. Custom synthesis is available. Send your inquiries for more information. | London |
| 1,2-Distearoyl-sn-glycero-3-phospho-L-serine sodium salt | 1,2-Distearoyl-sn-glycero-3-phospho-L-serine sodium salt, an imperative lipidic component, finds application in developing liposomes deployed for efficacious drug delivery. This compound exhibits a remarkable efficacy in targeting neoplastic cells and delivering pharmacological agents directly to the site of the malignancy. Moreover, this chemical entity holds immense potential in combating neurodegenerative maladies, such as Alzheimer's. Group: Pharmaceutical. Alternative Names: 3-sn-Phosphatidyl-L-serine, distearoyl sodium salt; DSPS-Na; PS(18:0/18:0); (2S,8R)-2-Amino-5-hydroxy-11-oxo-8-[(1-oxooctadecyl)oxy]-4,6,10-trioxa-5-phosphaoctacosanoic acid 5-oxide sodium salt. CAS No. 321595-13-5. Pack Sizes: 25 mg. Product ID: B4059-188606. Molecular formula: C42H81NNaO10P. Mole weight: 814.05. Custom synthesis is available. Send your inquiries for more information. | London |
| 13-Oxo-9E,11E-octadecadienoic acid | 13-Oxo-9E,11E-octadecadienoic acid is a lipid that is isolated from the leaves of Artemisia argyi. Group: Pharmaceutical. CAS No. 29623-29-8. Pack Sizes: 5 mg. Product ID: B0005-053960. Molecular formula: C18H30O3. Mole weight: 294.43. Custom synthesis is available. Send your inquiries for more information. | London |
| 1-Stearoyl-sn-glycero-3-phosphocholine | 1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated 18:0 lysophosphatidylcholine found in plasma and oxidized LD. Uses: 1-stearoyl-sn-glycero-3-phosphocholine can be used in lipid metabolism studies. Group: Pharmaceutical. Alternative Names: 1-Stearoyl-2-hydroxy-sn-glycero-3-PC; C18:0-PC; Lyso-PC; 1-Octadecanoyl-2-hydroxy-sn-glycero-3-phosphatidylcholine; PC(18:0/0:0); 1-Stearoyl-2-hydroxy-sn-glycero-3-Phosphocholine. CAS No. 19420-57-6. Pack Sizes: 100 mg. Product ID: BAT-006370. Molecular formula: C26H54NO7P. Mole weight: 523.68. Custom synthesis is available. Send your inquiries for more information. | London |
| (3S,5S)-Atorvastatin Acetonide tert-Butyl Ester | (3S,5S)-Atorvastatin Acetonide tert-Butyl Ester is a pharmaceutical compound employed in managing hyperlipidemia and cardiovascular disorders. It is a modified form of atorvastatin, acting as a potent HMG-CoA reductase inhibitor to mitigate cholesterol biosynthesis within hepatic cells. This medication plays a pivotal role in ameliorating lipid profiles and averting atherosclerosis progression. Uses: An intermediate for the preparation of (3s,5s)-atorvastatin. Group: Pharmaceutical. Alternative Names: (4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. CAS No. 472967-95-6. Pack Sizes: 25 mg. Product ID: B2692-117415. Molecular formula: C40H47FN2O5. Mole weight: 654.81. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(4-Chlorobenzylidene)-2,4-thiazolidinedione | 5-(4-Chlorobenzylidene)-2,4-thiazolidinedione, a well-researched organic compound, exhibits remarkable promise in treating diabetes mellitus type 2 owing to its ability to function as an agonist for peroxisome proliferator-activated receptor gamma (PPAR-γ). PPAR-γ is implicated in the modulation of glucose and lipid metabolism. Beyond its anti-diabetic attributes, this compound has been the subject of inquiry for its potential anti-cancer properties. The chemical's therapeutic significance is evidenced by the numerous investigations conducted on its biological activity. Group: Pharmaceutical. Alternative Names: 5-(4-Chloro-benzylidene)-thiazolidine-2,4-dione; 2,4-Thiazolidinedione, 5-[(4-chlorophenyl)methylene]-. CAS No. 24138-83-8. Pack Sizes: 50 mg. Product ID: B0001-284763. Molecular formula: C10H6ClNO2S. Mole weight: 239.673. Custom synthesis is available. Send your inquiries for more information. | London |
| A2-Iso5-2DC18 | A2-Iso5-2DC18 is a top-performing lipid for mRNA delivery in bone marrow-derived dendritic cells (BMDCs), BMDMs and HeLa cells. Group: Pharmaceutical. Alternative Names: ethyl 5,5-di((z)-heptadec-8-en-1-yl)-1-(3-(pyrrolidin-1-yl)propyl)-2,5-dihydro-1h-imidazole-2-carboxylate. Pack Sizes: 1mg;1g;10g. Molecular formula: C47H87N3O2. Mole weight: 726.21. Custom synthesis is available. Send your inquiries for more information. | London |
| ABTL-0812 | ABTL-0812 is an orally bioavailable, lipid analogue and inhibitor of raptor-mammalian target of rapamycin (mTOR), rictor-mTOR and dihydrofolate reductase with potential antineoplastic activity. It binds to and inhibits both mTORC1 and mTORC2, which may result in apoptosis and a decrease in proliferation in mTORC1/2-expressing tumor cells upon oral administration. It was developed by Ability Pharmaceuticals and is in phase I/II clinical trials for the treatment of solid tumors. It received orphan drug designation in the E.U. and in the U.S. for the treatment of neuroblastoma in 2015. Uses: Abtl-0812 has potential antineoplastic activity. it is used for the treatment of solid tumors. Group: Pharmaceutical. Alternative Names: ABTL0812; ABTL 0812; ABTL-0812; (9Z,12Z)-2-hydroxyoctadeca-9,12-dienoate. CAS No. 57818-44-7. Pack Sizes: 1mg;1g;10g. Product ID: 57818-44-7. Molecular formula: C18H31O3. Mole weight: 294.93. Custom synthesis is available. Send your inquiries for more information. | London |
| Acetylcorynoline | Acetylcorynoline, which can be extracted from the tubers of Corydalis ambigua, inhibits the maturing of bone marrow-derived dendritic cells in mice. However, it is only cytotoxic in amounts of greater than 20 μM. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. Acetylcorynoline significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; prevents α-synuclein aggregation; recovers lipid content in OW13 strain; restores food-sensing behavior, and dopamine levels; and prolongs life-span in 6-hydroxydopamine-treated N2 strain, thus showing its potential as a possible antiparkinsonian drug. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes. Uses: Antifungal/anti-inflammatory. Group: Pharmaceutical. Alternative Names: (5bR,6S,12bR)-5b,6,7,12b,13,14-Hexahydro-5b,13-dimethyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol 6-acetate; Corynoline acetate; O-Acetylcorynoline; [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-5b,13-dimethyl-, 6-acetate, (5bR,6S,12bR)-. CAS No. 18797-80-3. Pack Sizes: 10 mg. Product ID: B2703-464490. Molecular formula: C23H23NO6. Mole weight: 409.43. Custom synthesis is available. Send your inqui | London |
| AP1903 | AP1903 is a lipid-permeable tacrolimus analogue with homodimerizing activity. Dimerizer drug AP1903 homodimerizes an analogue of human protein FKBP12 (Fv) which contains a single acid substitution (Phe36Val) so that AP1903 binds to wild-type FKBP12 with 1000-fold lower affinity. Group: Pharmaceutical. Alternative Names: AP1903; AP 1903; AP-1903; Rimiducid. CAS No. 195514-63-7. Pack Sizes: 50 mg. Product ID: B1370-462662. Molecular formula: C78H98N4O20. Mole weight: 1411.63. Custom synthesis is available. Send your inquiries for more information. | London |
| Astaxanthin | Astaxanthin is a carotenoid pigment found mostly in animal organisms, but also occurring in plants. It is thought to be the precursor of astacin. It is a potent lipid-soluble antioxidant. It has broad application prospects in health products, medicine, cosmetics, food additives and aquaculture. Astaxanthin is a natural antioxidant with the strongest antioxidant and anti-aging ability in nature, and its antioxidant capacity is much higher than VE and β-carotene. It significantly enhances mitochondrial activity required for cell recombination and effectively protects the skin from UVA, UVB and blue light damage. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: Ovoester; Astaxanthine; (3S,3'S)-Astaxanthin; All-trans-Astaxanthin; 3,3'-Dihydroxy-β,β-carotene-4,4'-dione; 3,3'-Dhydroxy-4,4'-diketo-β-carotene; trans-Astaxanthin; (3S,3'S)-all-trans-Astaxanthin; (6S,6'S)-3,3'-((1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl)bis(6-hydroxy-2,4,4-trimethylcyclohex-2-enone). CAS No. 472-61-7. Pack Sizes: 10 g. Product ID: BBF-05817. Molecular formula: C40H52O4. Mole weight: 596.84. Custom synthesis is available. Send your inquiries for more information. | London |
| Atorvastatin USP Related Compound A | Atorvastatin USP Related Compound A is an impurity in the synthesis of Atorvastatin, which is a competitive HMG-CoA reductase inhibitor. Atorvastatin is a lipid-lowering medication of the statin class. Atorvastatin suppresses the production of cholesterol and prevents some cardiovascular diseases. Group: Pharmaceutical. Alternative Names: Calcium (3R,5R)-7-[2-isopropyl-4,5-diphenyl-3-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate (1:2); Atorvastatin Desfluoro impurity; (3R,5R)-7-[3-(phenylcarbamoyl)-2-isopropyl-4,5-diphenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoicacid, calcium salt; USP Atorvastatin Related Compound A; Defluoro Atorvastatin Calcium Salt; Atorvastatin Related Compound A; Calcium (3R,5R)-3,5-dihydroxy-7-(2-isopropyl-4,5-diphenyl-3-(phenylcarbamoyl)-1H-pyrrol-1-yl)heptanoate; 1H-Pyrrole-1-heptanoic acid, β,δ-dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-, calcium salt (2:1), (βR,δR)-; Calcium (βR,δR)-β,δ-dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoate (1:2). CAS No. 433289-83-9. Pack Sizes: 100 mg. Product ID: B0190-168852. Molecular formula: C66H70CaN4O10. Mole weight: 1119.38. Custom synthesis is available. Send your inquiries for more information. | London |
| Avicularin | Avicularin, a natural plant flavonoid isolated from the herbs of Polygonum aviculare, exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. By decreasing C/EBPα-activated GLUT4-mediated glucose uptake in adipocytes and potently inhibiting fatty acid synthase, avicularin can inhibit the accumulation of the intracellular lipids. Uses: Anti-inflammatory. Group: Pharmaceutical. Alternative Names: Fenicularin; Quercetin 3-alpha-L-arabinofuranoside; Avicularoside. CAS No. 572-30-5. Pack Sizes: 10 mg. Product ID: NP1949. Molecular formula: C20H18O11. Mole weight: 434.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Benfotiamine | Benfotiamine is an amphiphilic S-acyl thiamine derivative used as a lipid soluble alternative source of bioavailable thiamine. Benfotiamine is being investigated in a variety of therapeutic applications. Uses: Adjuvants, immunologic. Group: Pharmaceutical. Alternative Names: Benzenecarbothioic acid, S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propen-1-yl] ester; Benzoylthiamine monophosphate; Berdi; Betivina; Bietamine; Biotamin; Milgamma; Nitanevril; S-Benzoylthiamine O-monophosphate; Tabiomyl; Vitanevril; BTMP; Benzenecarbothioic acid, S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propenyl] ester; Benzoic acid, thio-, S-ester with N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)formamide dihydrogen phosphate (ester); Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)-, S-benzoate O-(dihydrogen phosphate); 8088CB; Benfothiamine; Benzoylthiamine O-monophosphate; N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)formamide S-benzoate O-phosphate; Neurostop; S-Benzoylthiamine monophosphate. CAS No. 22457-89-2. Pack Sizes: 500 g. Product ID: B1370-063311. Molecular formula: C19H23N4O6PS. Mole weight: 466.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Blumeatin | Blumeatin is found in tea and is extracted from the herbs of Blumea balsamifera. It can enhance adipocyte differentiation by increasing triglyceride levels in 3T3L1 cells. It also can increase the accumulation of lipid droplets and induce upregulation of the expression of the adipocyte-specific genes GLUT4 and aP2. It inhibits the increase of liver triglyceride and serum alanine aminotransferase, and increases serum beta-lipoprotein, liver glycogen and triglyceride content in CCl4-intoxicated rats, thus shorten the pentobarbital sleeping time in CCl4-intoxicated mice. It shows free radical scavenging activity, xanthine oxidase (XO) inhibitory activity and antioxidant properties. It can protect liver against injury induced by CCl4 and TAA. Group: Pharmaceutical. Alternative Names: 5,3',5'-Trihydroxy-7-methoxyflavanone; 2-(3,5-Dihydroxyphenyl)-5-hydroxy-7-methoxy-3,4-dihydro-2H-1-benzopyran-4-one. CAS No. 118024-26-3. Pack Sizes: 10 mg. Product ID: B1370-267733. Molecular formula: C16H14O6. Mole weight: 302.28. Custom synthesis is available. Send your inquiries for more information. | London |
| C16 Ceramide | C16 ceramide is an endogenous ceramide, generated by ceramide synthase 6 (CerS6), that acts as a lipid second messenger to regulate apoptosis and stress signaling. It has also been found to activate NF-κB and PKCζ3. Uses: A predominant, rather hydrophobic natural ceramide. activates a cytosolic serine/threonine protein phosphatase in t9 cells; induces egf receptor phosphorylation in a-431 cells; stimulates ceramide-activated protein kinase. Group: Pharmaceutical. Alternative Names: C16 Ceramide (d18:1/16:0); N-(hexadecanoyl)-sphing-4-enine; N-Palmitoylsphingosine. CAS No. 24696-26-2. Pack Sizes: 100 mg. Product ID: B1370-059982. Molecular formula: C34H67NO3. Mole weight: 537.9. Custom synthesis is available. Send your inquiries for more information. | London |
| (-)-Catechin gallate | (-)-Catechin gallate, a minor polyphenolic constituent in green tea, is used to study its cytotoxicity. It enhances Fe(2+)-induced, lipid peroxidation. It also inhibits aromatase activity, an enzyme that converts androgens to estrogen and is thought to play a role in the etiology of breast cancer. Uses: (-)-catechin gallate has been found to be probably effective in restraining tyrosine phosphorylation caused by vegf and have potential activity in the study of breast cancer. Group: Pharmaceutical. Alternative Names: (-)-CG; (-)-Catechin gallate; (2S,3R)-2-(3,4-Dihydroxyphenyl)-3-(3,4,5-trihydroxybenzoyloxy)-3,4-dihydro-2H-1-benzopyran-5,7-diol; 3,4,5-Trihydroxybenzoic acid [[(2S)-2β-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran]-3α-yl] ester. CAS No. 130405-40-2. Pack Sizes: 25 mg. Product ID: B2703-464825. Molecular formula: C22H18O10. Mole weight: 442.37. Custom synthesis is available. Send your inquiries for more information. | London |
| CAY10499 | Monoglyceride lipase (MGL) plays an important role in the metabolism of the lipid transmitter 2-arachidonoylglycerol (2-AG). CAY10499 is a potent and selective monoglyceride lipase (MGL) inhibitor exhibiting an IC50 of 90 nM for the recombinant enzyme. It is also a non-selective lipase inhibitor (IC50s = 144, 90, and 14 nM for human recombinant MAGL, HSL, and FAAH, respectively). CAY10499 inhibits the growth of MCF-7, MDA-MB-231, COV318, and OVCAR-3 cancer cells (IC50s = 4.2, 46, 106.7, and 79.8 mM, respectively). Group: Pharmaceutical. Alternative Names: CAY-10499; CAY 10499; Magl-IN-5. CAS No. 359714-55-9. Pack Sizes: 100 mg. Product ID: B1370-292092. Molecular formula: C18H17N3O5. Mole weight: 355.34. Custom synthesis is available. Send your inquiries for more information. | London |
| Ceramide NP | Ceramide NP is a ceramide 3 lipid with aggregation behavior. Ceramide NP has multiple physiological functions like a penetration enhancer and co-emulsifier, playing an important role in barrier function stability. Group: Pharmaceutical. Alternative Names: Ceramide 3B; Ceramide 3; Ceramide IIIB; N-octadecanoylphytosphingosine. CAS No. 178436-06-1. Pack Sizes: 5 g. Product ID: B1370-099098. Molecular formula: C36H71NO4. Mole weight: 581.95. Custom synthesis is available. Send your inquiries for more information. | London |
| Choline Fenofibrate | Choline fenofibrate is a hydrophilic formulation of fenofibric acid that acts primarily by activating peroxisome proliferator-activated receptor alpha (PPARα). This nuclear receptor modulates the transcription of genes involved in lipid metabolism. Once activated, PPARα increases the expression of lipoprotein lipase (LPL), which hydrolyzes triglycerides in lipoproteins, thereby reducing plasma triglyceride levels. It also decreases the production of apolipoprotein C-III (ApoC-III), an inhibitor of LPL, further promoting triglyceride breakdown. Additionally, choline fenofibrate stimulates the synthesis of high-density lipoprotein cholesterol (HDL-C) by upregulating the expression of apolipoprotein A-I (ApoA-I) and apolipoprotein A-II (ApoA-II). This multifaceted mechanism helps in managing mixed dyslipidemia by lowering triglycerides and increasing HDL-C levels. Group: Pharmaceutical. Alternative Names: Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate (1:1); Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid (1:1); ABT 335; FNFC; Trilipix. CAS No. 856676-23-8. Pack Sizes: 5 g. Product ID: B0084-259938. Molecular formula: C22H28ClNO5. Mole weight: 421.91. Custom synthesis is available. Send your inquiries for more information. | London |
| CMX 001 | CMX 001 is an antiviral inhibitor, working against BK polymavirus replication in primary human urothelial cells.An alkoxyalkyl ester prodrug containing the synthetic, acyclic nucleoside monophosphate analog cidofovir linked, through its phosphonate group, to a lipid, 3-hexadecyloxy-1-propanol, with antiviral activity against double-stranded DNA viruses. Uses: Broad spectrum antiviral drug. Group: Pharmaceutical. Alternative Names: CMX 001; CMX-001; CMX001; HDP-CDV; HDPCDV; Brincidofovir; [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethyl-(3-hexadecoxypropoxy)phosphinic acid. CAS No. 444805-28-1. Pack Sizes: 50 mg. Product ID: B0084-459195. Molecular formula: C27H52N3O7P. Mole weight: 561.7. Custom synthesis is available. Send your inquiries for more information. | London |
| Coenzyme Q9 | Coenzyme Q9 is a co-enzyme that is lipid solumbe compononet of cell membranes. It is useful in electron and proton transport of liposome systems. Coenzyme Q9 improves left ventricular performance and reduces myocardial infarct size and cardiomyocyte apoptosis. Group: Pharmaceutical. Alternative Names: 2,5-cyclohexadiene-1,4-dione, 2,3-dimethoxy-5-methyl-6-((2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethyl-2,6,10,14,18,22,26,30,34-hexatriacontanonaen-1-yl)-; coenzyme Q9; CoQ9; ubiquinone 9; ubiquinone 9, (Z,Z,Z,Z,Z,E,E,E)-isomer; ubiquinone Q-9; ubiquinone-9. CAS No. 303-97-9. Pack Sizes: 50 mg. Product ID: B2699-305013. Molecular formula: C54H82O4. Mole weight: 795.23. Custom synthesis is available. Send your inquiries for more information. | London |
| Curcumin | Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). Curcumin is a natural phenolic antioxidant extracted from the rhizome of turmeric, curcuma, mustard, curry, turmeric and so on. It is a rare pigment with diketone in the plant kingdom. It is a commonly used seasoning and food coloring and is non-toxic. It has the pharmacological effects of making the uterus produce paroxysmal contractions, reducing blood cholesterol, anti-gallbladder, anti-infection, antiviral, antibacterial, antioxidant (stronger than α-tocopherol), anticoagulation, lowering blood lipids and anti-atherosclerosis. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione; (E,E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione; Natural Yellow 3; Curcuma; Curcumin I; Curcumine; Diferuloylmethane; Haidr; Halad; Haldar; Ukon; Turmeric Yellow; NSC32982. CAS No. 458-37-7. Pack Sizes: 1 kg. Product ID: NP5248. Molecular formula: C21H20O6. Mole weight: 368.38. Custom synthesis is available. Send your inquiries for more information. | London |
| Cynarin | Cynarin, phenolic compound, is an antichoke agent with a variety of biological activities including antioxidant, antihistamic and antiviral activities. Cynarin is used in weight loss and lipid-lowering formulas, liver protection and anti-alcoholic drugs, etc. Group: Pharmaceutical. Alternative Names: Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1R,3R,4S,5R)-; (1R,3R,4S,5R)-1,3-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxycyclohexanecarboxylic acid; Cinnamic acid, 3,4-dihydroxy-, 1-carboxy-4,5-dihydroxy-1,3-cyclohexylene ester; Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-4,5-dihydroxy-, (1R,3R,4S,5R)-; Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-4,5-dihydroxy-, [1R-(1α,3α,4α,5β)]-; Cynarine; 1,3-Dicaffeoylquinic acid; 1,5-Dicaffeoylquinic acid; Cinarin; Cinarine. CAS No. 30964-13-7. Pack Sizes: 25 mg. Product ID: B2703-007275. Molecular formula: C25H24O12. Mole weight: 516.45. Custom synthesis is available. Send your inquiries for more information. | London |
| CZ415 | CZ415 is a highly selective potent mTOR inhibitor with little activity on other lipid and protein kinases with efficacy in a collagen induced arthritis model and exhibits excellent cell permeability. In the issue, Bergamini et al., who has identified CZ415, confirmed with its extraordinary selectivity, drug-like properties and proven efficacy in vivo, CZ415 represents an ideal molecule for the pharmacological investigation of mTOR pathophysiological role in vivo. Assessed in dose response format from HEK293T cells after treatment with CZ415: 1. inhibition of S6RP (downstream of mTORC1) phosphorylation in HEK293T: IC50 = 14.5 nM; 2. inhibition of Akt (mTORC2 substrate) phosphorylation in HEK293T: IC50 = 14.8 nM; 3. inhibition of IFNγ release in stimulated human whole blood: IC50 = 226 nM. Group: Pharmaceutical. Alternative Names: CZ415; CZ-415; CZ 415; (S)-1-(4-(7,7-dimethyl-4-(3-methylmorpholino)-6,6-dioxido-5,7-dihydrothieno[3,4-d]pyrimidin-2-yl)phenyl)-3-ethylurea. CAS No. 1429639-50-8. Pack Sizes: 5 mg. Product ID: B0084-474821. Molecular formula: C22H29N5O4S. Mole weight: 459.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Deoxyandrographolide | Deoxyandrographolide is a natural compound extracted from the herbs of Andrographis paniculata (Burm. f.) Nees. It could potently inhibit the growth of liver (HepG2 and SK-Hep1) and bile duct (HuCCA-1 and RMCCA-1) cancer cells. It controlled ethanol-induced hepatosteatosis by interfering with dysregulation of lipid metabolism. It was capable of preventing the development of fatty liver through AMPK-mediated regulation of lipid metabolism. It reduced the extracellular acidification rate and the intracellular alkalinization in a dose-dependent manner in concentrations between 10-100 microM. It reduced PAF-induced calcium flux in the presence of extracellular calcium. It mediated activation of adenylate cyclase-cAMP signaling leading to up-regulation of cNOS may provide a promising approach in the prevention of liver diseases during chronic alcoholism. Uses: Deoxyandrographolide could potently inhibit the growth of liver (hepg2 and sk-hep1) and bile duct (hucca-1 and rmcca-1) cancer cells. it controlled ethanol-induced hepatosteatosis by interfering with dysregulation of lipid metabolism. it reduced the extracellular acidification rate and the intracellular alkalinization in a dose-dependent manner in concentrations between 10-100 microm. it reduced p. Group: Pharmaceutical. Alternative Names: 4-[2-[(4aS,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-3,4,4a,6,7,8-hexahydronaphthalen-1-yl]ethyl]-2H-furan-5-one;2 | London |
| DLin-MC4-DMA | DLin-MC4-DMA is a cationic lipid which can be used for delivery of nucleic acids. Group: Pharmaceutical. Alternative Names: DLin-M-C4-DMA; (10Z,13Z)-1-(9Z,12Z)-9,12-Octadecadien-1-yl-10,13-nonadecadien-1-yl 5-(dimethylamino)pentanoate. CAS No. 1226909-66-5. Pack Sizes: 50 mg. Product ID: B1370-427866. Molecular formula: C44H81NO2. Mole weight: 656.12. Custom synthesis is available. Send your inquiries for more information. | London |
| DOTMA | DOTMA is one of the first cationic lipid used for gene transfection. DOTMA carries a positive charge on the surface of liposomes which condenses anionic nucleic acids and promotes efficient interactions between the cell membrane and the liposome. Group: Pharmaceutical. Alternative Names: 1,2-Di-O-Octadecenyl-3-Trimethylammonium Propane; Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride; N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium. CAS No. 104872-42-6. Pack Sizes: 50 mg. Product ID: BAT-006262. Molecular formula: C42H84ClNO2. Mole weight: 670.57. Custom synthesis is available. Send your inquiries for more information. | London |
| DPhPC | DPhPC (1,2-Diphytanoyl-sn-glycero-3-PC) is a phospholipid containing the tetramethylated long-chain (16:0) diphytanic acid at the sn-1 and sn-2 positions, which has been used in the creation of lipid bilayer membranes. Group: Pharmaceutical. Alternative Names: Diphytanoyl Phosphatidylcholine; 1,2-Diphytanoyl-sn-glycero-3-PC; 1,2-diphytanoylphosphatidylcholine; 1,2-di-(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phosphocholine. CAS No. 207131-40-6. Pack Sizes: 500 mg. Product ID: BAT-006268. Molecular formula: C48H96NO8P. Mole weight: 846.27. Custom synthesis is available. Send your inquiries for more information. | London |
| DSPE-PEG | MPEG2000-DSPE Sodium Salt can be used for the preparation of stabilized nucleic acid-lipid particllipid particles (SNALPs), which represent some of the earliest and best functional siRNA-ABC nanoparticles described. Group: Pharmaceutical. Alternative Names: Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-ω-methoxy-, sodium salt (1:1); Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-ω-methoxy-, monosodium salt; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-mPEG-2000, sodium salt; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol) monosodium salt; DSPE-PEG 2000; DSPE-PEG 5000; MPEG 2000 DSPE; MPEG-2000 DSPE; MPEG-DSPE 5000; N-(Carbonyl-methoxypolyethylene glycol 2000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt; N-(Carbonyl-methoxypolyethylene glycol)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt; Sunbright DSPE 020CN. CAS No. 247925-28-6. Pack Sizes: 1 g. Product ID: B1370-291962. Molecular formula: (C2H4O)nC43H83NO10P.Na. Custom synthesis is available. Send your inquiries for more information. | London |
| DSPE-PEG Azide (ammonium salt) | DSPE-PEG azide is a functionalized polyethylene glycol (PEG) lipid, used to prepare conjugated polymer nanoparticles. Group: Pharmaceutical. Alternative Names: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carbonyl-azido(polyethylene glycol)-5000] (ammonium salt). CAS No. 1938081-40-3. Pack Sizes: 100 mg. Product ID: B1370-286473. Molecular formula: C268H536N5O122P (average MW due to polydispersity of PEG). Mole weight: 5812.12. Custom synthesis is available. Send your inquiries for more information. | London |
| Eriocitrin | Eriocitrin is a powerful antioxidative flavonoid in lemon with lipid-lowering effects in a rat model of high-fat diet. It might play an important role in the control of the change in glutathione redox status in rat liver during exercise. These findings showed that Eriocitrin was effective in the prevention of oxidative damages caused by acute exercise-induced oxidative stress. Eriocitrin was suggested to be metabolized by intestinal bacteria, and then eriodictyol and 3,4-dihydroxyhydrocinnamic of its metabolite were absorbed. Following administration of Eriocitrin, plasma exhibited an elevated resistance effect to lipid peroxidation. Eriocitrin metabolites functioning as antioxidant agents are discussed. Uses: Antioxidant. Group: Pharmaceutical. Alternative Names: (S)-3',4',5,7-TETRAHYDROXYFLAVANONE-7-[6-O-(ALPHA-L-RHAMNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE]; ERIOCITRIN; ERIODICTYL-7-RUTINOSIDE; ERIODICTYOL-7-O-RUTINOSIDE; ERIODICTYOL-7-RUTINOSIDE; (S)-7-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-4H-benzopyran-4-one; (s)-3',4',5,7-tetrahydroxyflavanone-7-[6-o-(α-l-rhamnopyranosyl)-β-d-glucopy. CAS No. 13463-28-0. Pack Sizes: 25 mg. Product ID: B2703-465065. Molecular formula: C27H32O15. Mole weight: 596.53. Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Phenoxy Glucuronide-[d4] | Ezetimibe Phenoxy Glucuronide-[d4] is the labelled analogue of Ezetimibe Phenoxy Glucuronide, which is a metabolite of Ezetimibe. Ezetimibe is a medication used to treat high blood cholesterol and certain other lipid abnormalities. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. Alternative Names: Ezetimibe D4 Phenoxy Glucuronide. CAS No. 1426174-41-5. Pack Sizes: 10 mg. Product ID: BLP-005427. Molecular formula: C30H25D4F2NO9. Mole weight: 589.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Fingolimod | Fingolimod, a derivative of the fungal metabolite myriocin, is an antagonist of S1P (IC50 of 0.033 nM) which is an extracellular lipid mediator. Fingolimod has been used as an immunomodulating drug to treat multiple sclerosis (MS). Group: Pharmaceutical. Alternative Names: FTY 720; FTY-720; FTY720; 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol. CAS No. 162359-55-9. Pack Sizes: 50 mg. Product ID: NP3693. Molecular formula: C19H33NO2. Mole weight: 307.47. Custom synthesis is available. Send your inquiries for more information. | London |
| FIPI | FIPI, a derivative of halopemide, is a potent and selective phospholipase D (PLD) inhibitor with IC50 values of 20 and 25 nM for PLD2 and PLD1 respectively. It attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. It rapidly blocks in vivo PA production with subnanomolar potency. It has good pharmacokinetic parameters in rats. It did not significantly inhibit p38 or ERK phosphorylation in bone marrow-derived macrophages stimulated with lipopolysaccharide. It prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. Group: Pharmaceutical. Alternative Names: 5-Fluoro-2-Indolyl des-Chlorohalopemide; N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-5-fluoro-1H-indole-2-carboxamide; 5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide. CAS No. 939055-18-2. Pack Sizes: 100 mg. Product ID: B2693-438324. Molecular formula: C23H24FN5O2. Mole weight: 421.47. Custom synthesis is available. Send your inquiries for more information. | London |
| Gemcabene | Gemcabene is an orally available lipid-lowering small molecule designed to target known lipid metabolic pathways, as an adjunctive therapy to reduce LDL-C, hsCRP and triglycerides (TGs). Currentl, Gemcabene is under Phase-II clinical trials in Hypertriglyceridaemia in USA. Group: Pharmaceutical. Alternative Names: 6-(5-carboxy-5-methyl-hexoxy)-2,2-dimethyl-hexanoic acid; gemcabene; 6,6'-oxybis(2,2-dimethylhexanoic acid); PD72953; PD 72953; PD-72953. CAS No. 183293-82-5. Pack Sizes: 100 mg. Product ID: B0084-244917. Molecular formula: C16H30O5. Mole weight: 302.41. Custom synthesis is available. Send your inquiries for more information. | London |
| Geranylgeraniol | An intermediate in the lipidation of proteins, which plays a great importance for a variety of biological processes such as cell signalling. Group: Pharmaceutical. Alternative Names: Tetraprenol; Geranyl geraniol; (E,E,E)-Geranylgeraniol; trans-Geranylgeraniol; 3,7,11,15-tetramethylhexadeca-2E,6E,10E,14-tetraen-1-ol. CAS No. 24034-73-9. Pack Sizes: 5 g. Product ID: B2692-059518. Molecular formula: C20H34O. Mole weight: 290.48. Custom synthesis is available. Send your inquiries for more information. | London |
| GGTI-2418 | GGTI-2418 is a synthetic peptidomimetic inhibitor of geranylgeranyltransferase I (GGTase I) that appears to induce apoptosis by downregulating several pivotal oncogenic and tumor survival pathways. GGTase I catalyzes the lipid posttranslational modification which is required for the function of Rho GTPases (frequently found aberrantly activated in human cancer). GGTase I inhibitors block Rho function in cancer cells and induce a G1 phase cell cycle arrest by a mechanism involving induction of the CDK inhibitors p21waf and p27kip, CDK2 and CDK4 inhibition and hypophoshorylation of the tumor suppressor Rb. GGTase I inhibitors also induce apoptosis by a mechanism involving downregulation of the expression of survivin and suppression of the activation of PI3K/Akt. Group: Pharmaceutical. Alternative Names: GGTI 2418; GGTI-2418; GGTI 2418. CAS No. 501010-06-6. Pack Sizes: 2.5 mg. Product ID: B0084-462530. Molecular formula: C23H31N5O4. Mole weight: 441.532. Custom synthesis is available. Send your inquiries for more information. | London |
| Idebenone | Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant. Idebenone is a smart promoting drug, which is mainly used in the treatment of many degenerative diseases of the central nervous system related to oxidative compressions, such as Parkinson's disease, Alzheimer's disease, multi-infarct dementia, cerebral anemia and cerebral failure, and is also used in the treatment of Friedreich's ataxia. It can also be used in cosmetic formulations to clear free radicals, inhibit lipid peroxidation, inhibit inflammation, inhibit DNA damage, photoprotection, reduce pigmentation, and other cosmetic effects. Group: Pharmaceutical. Alternative Names: CV 2619; CV-2619; CV2619; Catena; Raxone; Sovrima; 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione; 2,3-Dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone; 2-(10-Hydroxy-decyl)-5,6-dimethoxy-3-methyl-[1,4]benzoquinone; Avan; Daruma; Hydroxydecyl ubiquinone; Mnesis. CAS No. 58186-27-9. Pack Sizes: 10 g. Product ID: NP3168. Molecular formula: C19H30O5. Mole weight: 338.44. Custom synthesis is available. Send your inquiries for more information. | London |
| Ku-0063794 | KU-0063794 is an inhibitor of both mTORC1 and mTORC2 with an IC50 of approximately 10 nM, but does not suppress the activity of 76 other protein kinases or seven lipid kinases, including Class 1 PI3Ks (phosphoinositide 3-kinases) at 1000-fold higher concentrations. KU-0063794 is cell permeant, suppresses activation and hydrophobic motif phosphorylation of Akt, S6K and SGK, but not RSK (ribosomal S6 kinase), an AGC kinase not regulated by mTOR. It also inhibited phosphorylation of the T-loop Thr308 residue of Akt phosphorylated by PDK1 (3-phosphoinositide-dependent protein kinase-1). It does not affect Thr308 phosphorylation in fibroblasts lacking essential mTORC2 subunits. KU-0063794 also suppressed cell growth and induced a G1-cell-cycle arrest. KU-0063794 will be useful in delineating the physiological roles of mTOR and may have utility in treatment of cancers in which this pathway is inappropriately activated. Uses: Differentiation. Group: Pharmaceutical. Alternative Names: KU0063794; KU-0063794; KU 0063794; Ku0063794; Ku 0063794; Ku-0063794; KU63794; KU 63794; KU-63794; [5-[2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-morpholin-4-ylpyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol. CAS No. 938440-64-3. Pack Sizes: 100 mg. Product ID: B0084-100850. Molecular formula: C25H31N5O4. Mole weight: 465.554. Custom synthesis is available. Send your inquiries for more information. | London |
| Licoisoflavone A | Licoisoflavone A, a potential MRP inhibitor, is a natural flavonoid derived from the roots of Glycyrrhiza uralensis Fisch. It inhibits lipid peroxidation with an IC50 of 7.2 μM. Licoisoflavone A and Licoisoflavone B inhibit copper-induced protein oxidative modification of mice brain homogenate in vitro. Group: Pharmaceutical. Alternative Names: 2',4',5,7-Tetrahydroxy-3'-(3,3-dimethylallyl)isoflavone; 3-[2,4-Dihydroxy-3-(3-methyl-2-butenyl)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one; Phaseoluteone; 4H-1-Benzopyran-4-one, 3-[2,4-dihydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-; 2',4',5,7-Tetrahydroxy-3'-(3,3-dimethylallyl)isoflavone; 3'-Isopentenyl-2',4',5,7-tetrahydroxyisoflavone. CAS No. 66056-19-7. Pack Sizes: 5 mg. Product ID: BBF-05885. Molecular formula: C20H18O6. Mole weight: 354.35. Custom synthesis is available. Send your inquiries for more information. | London |
| Liquiritin | Liquiritin is a natural flavonoid compound found in the root of Glycyrrhiza glabra L. Liquiritin shows potential antidepressant-like effection and can increase SOD activity, inhibit lipid peroxidation, and lessen production of MDA. Uses: Antidepressant. Group: Pharmaceutical. Alternative Names: 4,7-Dihydroxyflavanone-4-(b-D-glucopyranoside); Likviritin; Liquiritoside. CAS No. 551-15-5. Pack Sizes: 20 mg. Product ID: NP1916. Molecular formula: C21H22O9. Mole weight: 418.39. Custom synthesis is available. Send your inquiries for more information. | London |
| LY-2562175 | LY2562175 is a potent and selective FXR agonist in vitro. It has robust lipid modulating properties, lowering LDL and triglycerides while raising HDL in preclinical species. It was developed by Eli Lilly and Company and in clinic phase 1 trials with no progress. Uses: Ly2562175 has robust lipid modulating properties, lowering ldl and triglycerides while raising hdl in preclinical species. Group: Pharmaceutical. Alternative Names: LY2562175; LY 2562175; LY-2562175;6-(4-((5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic acid. CAS No. 1103500-20-4. Pack Sizes: 10 mg. Product ID: B2693-475063. Molecular formula: C28H27Cl2N3O4. Mole weight: 540.44. Custom synthesis is available. Send your inquiries for more information. | London |
| MBX-2982 | MBX-2982 is a potential first-in-class treatment for type 2 diabetes that targets G protein-coupled receptor 119 (GPR119), a receptor that interacts with bioactive lipids known to stimulate glucose-dependent insulin secretion. Preclinical data indicate that MBX-2982 is a potent selective orally-active GPR119 agonist that functions through a unique dual mechanism of action. First, it acts directly on the beta cell to increase insulin secretion. In addition, MBX-2982 stimulates release of the incretin GLP-1 from the gut. This dual action is unique and may offer improved glucose homeostasis over existing diabetes therapies, with potential for weight loss and improved islet health. Group: Pharmaceutical. Alternative Names: Pyrimidine, MBX-2982; MBX 2982; MBX2982; SAR-260093; SAR260093; SAR 260093; 5-ethyl-2-(4-(4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)-2-thiazolyl)-1-piperidinyl)-; 4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)-2-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yl)thiazole; B5TRY67L51. CAS No. 1037792-44-1. Pack Sizes: 20 mg. Product ID: B0084-456604. Molecular formula: C22H24N8OS. Mole weight: 448.549. Custom synthesis is available. Send your inquiries for more information. | London |
| Methylcobalamin | Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. The physiologically active forms of vitamin B12 include methylcobalamin and adenosylcobalamin, whereas hydroxocobalamin (vitamin B12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms. Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine. Group: Pharmaceutical. Alternative Names: Cobinamide, Co-methyl-, dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3); Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole; Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D. CAS No. 13422-55-4. Pack Sizes: 1mg;1g;10g. Product ID: NP3442. Molecular formula: C63H91CoN13O14P. Mole weight: 1344.38. Custom synthesis is available. Send your inquiries for more information. | London |
| Mevastatin | It is produced by the strain of Penicillum brevicompactum. It has weak anti-fungal activity and can inhibit the key enzyme (3-hydroxy-3-methyl glutaryl coenzyme A(HMGCoA) reductase) in the cholesterol biosynthesis pathway. It has been shown to lower cholesterol in animals and humans. It led the discovery of statins, lipid-lowering drugs. It is now used as a biochemical reagent. Uses: Hydroxymethylglutaryl-coa reductase inhibitors. Group: Pharmaceutical. Alternative Names: Mevastatina; Mevastatine; Mevastatinum; ML-236B; Compactin; CS-500; CS 500; CS500; ML-236B; ML 236B; ML236B; Antibiotic ML 236B. CAS No. 73573-88-3. Pack Sizes: 25 g. Product ID: BBF-01732. Molecular formula: C23H34O5. Mole weight: 390.51. Custom synthesis is available. Send your inquiries for more information. | London |
| Minocycline hydrochloride | Minocycline (INN) is a semi-synthetic broad-spectrum tetracycline antibiotic. Minocycline hydrochloride is the most lipid-soluble form, which binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis. In combination with CHIR 99021, (S)-(+)-Dimethindene maleate and human leukemia inhibitory factor, it induces the formation of extended pluripotent stem (EPS) cells. Group: Pharmaceutical. Alternative Names: Minocycline HCl; Arestin; Minomycin. CAS No. 13614-98-7. Pack Sizes: 5 g. Product ID: BBF-03822. Molecular formula: C23H27N3O7.HCl. Mole weight: 493.94. Custom synthesis is available. Send your inquiries for more information. | London |
| MitoPerOx | MitoPerOx is a fluorescent probe that can be used for measuring changes in lipid peroxidation within mitochondria. It is composed of a BODIPY fluorophore conjugated via a dienyl link to a triphenylphosphonium cation component that drives its accumulation in mitochondria. Group: Pharmaceutical. Alternative Names: (2-(3-(5,5-difluoro-7-((1E,3E)-4-phenylbuta-1,3-dien-1-yl)-5H-5λ4,6λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)propanamido)ethyl)triphenylphosphonium, monobromide. CAS No. 1392820-50-6. Pack Sizes: 10 mg. Product ID: B1370-284974. Molecular formula: C42H38BF2BrN3OP. Mole weight: 760.46. Custom synthesis is available. Send your inquiries for more information. | London |
| Oleandrin | Oleandrin, also known as PBI-05204, is a lipid soluble cardiac glycoside with potential antineoplastic activity. Upon administration, oleandrin specifically binds to and inhibits the alpha3 subunit of the Na/K-ATPase pump in human cancer cells. This may inhibit the phosphorylation of Akt, upregulate MAPK, inhibit NF-kb activation and inhibit FGF-2 export and may downregulate mTOR thereby inhibiting p70S6K and S6 protein expression. All of this may lead to an induction of apoptosis. As cancer cells with relatively higher expression of the alpha3 subunit and with limited expression of the alpha1 subunit more sensitive to oleandrin, one may predict the tumor response to treatment with lipid-soluble cardiac glycosides such as oleandrin based on the tumors Na/K-ATPase pump protein subunit expression. Overexpression of the alpha3 subunit in tumor cells correlates with tumor proliferation. Uses: Anti-proliferative. Group: Pharmaceutical. Alternative Names: (3b,5b,16b)-16-(Acetyloxy)-3-[(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide; Neriolin; Corrigen. CAS No. 465-16-7. Pack Sizes: 10 mg. Product ID: NP6109. Molecular formula: C32H48O9. Mole weight: 576.72. Custom synthesis is available. Send your inquiries for more information. | London |
| Olumacostat glasaretil | OG (Olumacostat glasaretil) is a acetyl-coenzyme A carboxylase inhibitor. Acetyl-COA carboxylase is the key point for the first, rate-limiting step in de novo fatty acid synthesis. OG can inhibit in vitro human sebocyte lipid production, it can also reduce in vivo sebaceous gland size in hamster ears. Group: Pharmaceutical. Alternative Names: Olumacostat glasaretil; DRM01B; DRM-01B; DRM 01B. 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-(tetradecyloxy)furan-2-carboxylate. CAS No. 1261491-89-7. Pack Sizes: 25 mg. Product ID: B0084-475242. Molecular formula: C26H43NO7. Mole weight: 481.63. Custom synthesis is available. Send your inquiries for more information. | London |
| Panaxcerol C | Monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG) are the two nonionic lipid constituents of the thylakoid membrane of higher plant chloroplasts. MGDG and DGDG are present in the membrane at 56% and 29%, respectively, of the total lipid content. DGDG is a bilayer-forming lipid, while MGDG alone will only form hexagonal-II structures. Group: Pharmaceutical. Alternative Names: Monogalactosyldiacylglycerol (Plant); 1,2-diacyl-3-O-β-D-galactosyl-sn-glycerol; MGDG; 1-18:3-2-18:3-Monogalactosyldiacylglycerol; 18:3-18:3-MGDG; 1,2-Di-O-alpha-linolenoyl-3-O-beta-galactopyranosyl-sn-glycerol; 1,2-(9Z,12Z,15Z-octadecatrienoyl)-3-O-beta-D-galactosyl-sn-glycerol; (9Z,9'Z,12Z,12'Z,15Z,15'Z)-(S)-3-(((2R,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)propane-1,2-diyl bis(octadeca-9,12,15-trienoate); β-D-Galactopyranoside, (2S)-2,3-bis[[(9Z,12Z,15Z)-1-oxo-9,12,15-octadecatrien-1-yl]oxy]propyl. CAS No. 63180-02-9. Pack Sizes: 10 mg. Product ID: B2703-031639. Molecular formula: C45H74O10. Mole weight: 775.06. Custom synthesis is available. Send your inquiries for more information. | London |
| Parvodicin B1 | It is produced by the strain of Actinomadura paroosalo. It's a glycopeptide antibiotic. It has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and enterococcus faecalis. The terminal branching activity of lipid chains is greater than straight chains (C1>C2>C3>C4, B1>B2), and the chain length is greater than short chains (C2>B). It acts by inhibiting the synthesis of bacterial cell wall. Group: Pharmaceutical. Alternative Names: Antibiotic A-40926 A0; Ristomycin A aglycone, 5,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((9-methyl-1-oxodecyl)amino)-beta-D-glucopyranuronosyl)-42-o-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 110882-82-1. Pack Sizes: 1mg;1g;10g. Product ID: BBF-02668. Molecular formula: C82H86N8O29Cl2. Mole weight: 1718.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Parvodicin B2 | It is produced by the strain of Actinomadura paroosalo. It's a glycopeptide antibiotic. It has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and enterococcus faecalis. The terminal branching activity of lipid chains is greater than straight chains (C1>C2>C3>C4, B1>B2), and the chain length is greater than short chains (C2>B). It acts by inhibiting the synthesis of bacterial cell wall. Group: Pharmaceutical. Alternative Names: Antibiotic A-40926 A1; Antibiotic A 40926 factor A; Antibiotic A 40926A; Ristomycin A aglycone, 5,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((1-oxoundecyl)amino)-beta-D-glucopyranuronosyl)-42-o-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 110882-83-2. Pack Sizes: 1mg;1g;10g. Product ID: BBF-02669. Molecular formula: C82H86N8O29Cl2. Mole weight: 1718.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Parvodicin C2 | It is produced by the strain of Actinomadura paroosalo. It's a glycopeptide antibiotic. It has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and enterococcus faecalis. Parvodicin C1 and C2 have stronger antibacterial effects than Parvodicin C3 and C4. The antibacterial activity of Parvodicin C is 1-4 times stronger than Tecomycin and 2-4 times stronger than vancomycin. The terminal branching activity of lipid chains is greater than straight chains (C1>C2>C3>C4, B1>B2), and the chain length is greater than short chains (C2>B). The half-life of Parvodicin C1 is longer in vivo than vancomycin and Archeomycin. Group: Pharmaceutical. Alternative Names: Antibiotic A-40926 B1; Ristomycin A aglycone, 5,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((1-oxododecyl)amino)-beta-D-glucopyranuronosyl)-42-o-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 110882-85-4. Pack Sizes: 1mg;1g;10g. Product ID: BBF-02670. Molecular formula: C83H88N8O29Cl2. Mole weight: 1732.53. Custom synthesis is available. Send your inquiries for more information. | London |
| Perifosine | Perifosine is an orally active alkyl-phosphocholine compound with potential antineoplastic activity. Targeting cellular membranes, perifosine modulates membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti-apoptotic mitogen-activated protein kinase (MAPK) pathway and modulates the balance between the MAPK and pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. Perifosine has a lower gastrointestinal toxicity profile than the related agent miltefosine. Group: Pharmaceutical. Alternative Names: KRX-0401; KRX 0401; KRX0401; NKA17; NSC639966; NSC 639966; NSC-639966; D 21266; D-21266; D21266; D-21266N; N-Dimethylpiperidinium-4-yl(octadecyl)phosphate; 1,1-Dimethyl-4-[[(octadecyloxy)hydroxyphosphoryl]oxy]piperidinium inner salt. CAS No. 157716-52-4. Pack Sizes: 500 mg. Product ID: B0084-084985. Molecular formula: C25H52NO4P. Mole weight: 461.668. Custom synthesis is available. Send your inquiries for more information. | London |
| POPS-Na | POPS-Na is a negatively charged membrane lipid. It is also a reagent that triggered the release of 5-Aminolevulinic acid (5-ALA) from stealth liposomes. Group: Pharmaceutical. Alternative Names: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); POPS(16:0/18:1(9Z)); 16:0-18:1 PS (POPS) (sodium salt). CAS No. 321863-21-2. Pack Sizes: 100 mg. Product ID: B1370-188610. Molecular formula: C40H75NNaO10P. Mole weight: 784. Custom synthesis is available. Send your inquiries for more information. | London |
| Rosuvastatin EP Impurity A Calcium Salt | Rosuvastatin EP Impurity A Calcium Salt is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Group: Pharmaceutical. Alternative Names: 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-2-[[(2-hydroxy-2-methylpropyl)sulfonyl]methylamino]-6-(1-methylethyl)-5-pyrimidinyl]-3,5-dihydroxy-, calcium salt (2:1), (3R,5S,6E)-; (3R,5S,E)-7-(4-(4-Fluorophenyl)-2-((2-hydroxy-N,2-dimethylpropyl)sulfonamido)-6-isopropylpyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate Calcium Salt; S-Desmethyl-S-(2-hydroxy-2-methylpropyl) Rosuvastatin Calcium Salt; (3R,5S,6E)-7-[2-(2,N-Dimethyl-2-hydroxypropane-1-sulfonamido)-4-(4-fluorophenyl)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid calcium salt; Calcium (3R,5S,E)-7-{4-(4-fluorophenyl)-2-[(2-hydroxy-N,2-dimethylpropyl)sulfonamide]-6-isopropylpyrimidin-5-yl}-3,5-dihydroxyhept-6-enoate salt (1:2); USP Rosuvastatin Related Compound A; Rosuvastatin Related Compound A; Rosuvastatin USP Related Compound A. CAS No. 1714147-47-3. Pack Sizes: 5 mg. Product ID: B2694-010332. Molecular formula: C25H33FN3O7S.1/2Ca. Mole weight: 558.65. Custom synthesis is available. Send your inquiries for more information. | London |
| Rosuvastatin EP Impurity C Sodium Salt | Rosuvastatin EP Impurity C Sodium Salt is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Group: Pharmaceutical. Alternative Names: Rosuvastatin Impurity Sodium Salt; 5-Oxo Rosuvastatin Sodium Salt; Sodium (R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3-hydroxy-5-oxohept-6-enoate; (3R,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3-hydroxy-5-oxo-6-heptenoic Acid Sodium Salt; 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3-hydroxy-5-oxo-, sodium salt (1:1), (3R,6E)-; (3R,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3-hydroxy-5-oxo-6-heptenoic acid sodium salt. CAS No. 1620823-61-1. Pack Sizes: 10 mg. Product ID: B2694-479298. Molecular formula: C22H25FN3NaO6S. Mole weight: 501.51. Custom synthesis is available. Send your inquiries for more information. | London |
| Rosuvastatin EP Impurity D | Rosuvastatin EP Impurity D is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Group: Pharmaceutical. Alternative Names: Rosuvastatin Calcium EP Impurity D; N-(4-(4-Fluorophenyl)-5-((E)-2-((2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)vinyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide; N-[4-(4-Fluorophenyl)-5-[(1E)-2-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]ethen-1-yl]-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide; N-[4-(4-Fluorophenyl)-5-[(E)-2-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethenyl]-6-(1-methylethyl)-pyrimidin-2-yl]-N-methylmethanesulfonamide; Rosuvastatin Lactone; Methanesulfonamide, N-[4-(4-fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methyl-; N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide; Rosuvastatin-5S-lactone. CAS No. 503610-43-3. Pack Sizes: 10 mg. Product ID: B0194-069823. Molecular formula: C22H26FN3O5S. Mole weight: 463.53. Custom synthesis is available. Send your inquiries for more information. | London |
| Rosuvastatin EP Impurity FP-B (6R-isomer) calcium salt | Rosuvastatin EP Impurity FP-B (6R-isomer) calcium salt is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Group: Pharmaceutical. Alternative Names: (3R,5S)-5-((R)-8-fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoate calcium(II) salt; Benzo[h]quinazoline-6-pentanoic acid, 8-fluoro-5,6-dihydro-β,δ-dihydroxy-4-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-, calcium salt (2:1), (βR,δS,6R)-; (βR,δS,6R)-8-Fluoro-5,6-dihydro-β,δ-dihydroxy-4-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]benzo[h]quinazoline-6-pentanoic acid calcium salt; Rosuvastatin Dihydrobenzoquinazoline (6R)-Isomer calcium salt. CAS No. 854898-49-0. Pack Sizes: 20 mg. Product ID: B2699-009723. Molecular formula: C22H27FN3O6S.1/2Ca. Mole weight: 500.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Rosuvastatin EP Impurity FP-B (6S-isomer) calcium salt | Rosuvastatin EP Impurity FP-B (6S-isomer) calcium salt is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Group: Pharmaceutical. Alternative Names: Benzo[h]quinazoline-6-pentanoic acid, 8-fluoro-5,6-dihydro-β,δ-dihydroxy-4-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-, calcium salt (2:1), (βR,δS,6S)-; (3R,5S)-5-((S)-8-fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoate calcium(II) salt; (βR,δS,6S)-8-Fluoro-5,6-dihydro-β,δ-dihydroxy-4-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]benzo[h]quinazoline-6-pentanoic acid calcium salt; Rosuvastatin Dihydrobenzoquinazoline (6S)-Isomer calcium salt. CAS No. 854898-50-3. Pack Sizes: 20 mg. Product ID: B2699-009805. Molecular formula: C22H28FN3O6S.1/2Ca. Mole weight: 500.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Rosuvastatin EP Impurity G calcium salt | Rosuvastatin EP Impurity G calcium salt is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Group: Pharmaceutical. Alternative Names: Calcium (3S,5R,E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate salt (1:2); 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, calcium salt (2:1), (3S,5R,6E)-; Rosuvastatin Enantiomer; (3S,5R,6E)-Rosuvastatin Calcium Salt; Calcium (3S,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate; (3S,5R,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt (2:1). CAS No. 2414245-11-5. Pack Sizes: 5 mg. Product ID: B2694-383946. Molecular formula: C22H28FN3O6S.1/2Ca. Mole weight: 500.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Rosuvastatin EP Impurity K | Rosuvastatin EP Impurity K is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Group: Pharmaceutical. Alternative Names: (2Z,5S,6E)-7-[4-(4-Fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-5-hydroxyhepta-2,6-dienoic acid; Rosuvastatin EP Impurity K (2Z-Isomer); (S,2Z,6E)-7-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-hydroxyhepta-2,6-dienoic acid; 2,3-Dehydro-3-Deshydroxy-(2Z)-Rosuvastatin; 2,6-Heptadienoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-hydroxy-, (2Z,5S,6E)-; (2Z,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-hydroxy-2,6-heptadienoic acid; 2,3-Anhydro rosuvastatin. CAS No. 1422954-12-8. Pack Sizes: 10 mg. Product ID: B2694-010379. Molecular formula: C22H26FN3O5S. Mole weight: 463.52. Custom synthesis is available. Send your inquiries for more information. | London |
| Rosuvastatin EP Impurity M | Rosuvastatin EP Impurity M is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Group: Pharmaceutical. Alternative Names: Rosuvastatin Calcium EP Impurity M; (3R,5S,6E)-7-[2-(N-methylmethanesulfonamido)-4-phenyl-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid; (3R,5S,E)-3,5-dihydroxy-7-(4-isopropyl-2-(N-methylmethylsulfonamido)-6-phenylpyrimidin-5-yl)hept-6-enoic acid; 6-Heptenoic acid, 3,5-dihydroxy-7-[4-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-6-phenyl-5-pyrimidinyl]-, (3R,5S,6E)-; (3R,5S,6E)-3,5-Dihydroxy-7-[4-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-6-phenyl-5-pyrimidinyl]-6-heptenoic acid; Desfluoro Rosuvastatin. CAS No. 847849-66-5. Pack Sizes: 10 mg. Product ID: B2694-479315. Molecular formula: C22H29N3O6S. Mole weight: 463.55. Custom synthesis is available. Send your inquiries for more information. | London |
| Rosuvastatin Z-Isomer Calcium Salt | Rosuvastatin Z-Isomer Calcium Salt is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Group: Pharmaceutical. Alternative Names: 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, calcium salt (2:1), (3R,5S,6Z)-; Calcium (3R,5S,Z)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate; (3R,5S,6Z)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid calcium salt. CAS No. 1444772-08-0. Pack Sizes: 10 mg. Product ID: B2694-010409. Molecular formula: C22H27FN3O6S.1/2Ca. Mole weight: 500.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Simvastatin-[d3] | An isotope labelled of Simvastin. Simvastatin is a lipid-lowering medication and the primary uses of simvastatin are to treat dyslipidemia. Group: Pharmaceutical. Alternative Names: Simvastatin D3 lactone. CAS No. 1002347-61-6. Pack Sizes: 50 mg. Product ID: BLP-013128. Molecular formula: C25H35D3O5. Mole weight: 421.58. Custom synthesis is available. Send your inquiries for more information. | London |
| Simvastatin EP Impurity F | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. Alternative Names: Simvastatin USP Related Compound F; epi-Lovastatin; Lovastatin epimer; (2R)-2-Methylbutanoic Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester. CAS No. 79952-44-6. Pack Sizes: 50 mg. Product ID: B2694-261180. Molecular formula: C24H36O5. Mole weight: 404.55. Custom synthesis is available. Send your inquiries for more information. | London |
| Simvastatin EP Impurity H | An intermediate in the synthesis of Simvastatin, Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. Alternative Names: Lovastatin Lactone Diol; Monacolin J; Antibiotic MB 530A; 6(R)-[2-(8(S)-Hydroxy]-2(S),6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydro-1(S)-naphthyl]ethyl-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one. CAS No. 79952-42-4. Pack Sizes: 50 mg. Product ID: B2694-257205. Molecular formula: C19H28O4. Mole weight: 320.43. Custom synthesis is available. Send your inquiries for more information. | London |
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