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| Product | Description | |
|---|---|---|
| 1kg Deep Blue Pro Pool Multi Stain Remover | Deep Blue Pro Multi-Stain Remover Granules are used for the removal of coloured metal stains on swimming pool surfaces. The product contains a special blend of three organic acids and has been specifically developed to remove coloured stains (copper, iron and manganese) from swimming pool surfaces. Product may be sprinkled directly over the stained areas or evenly distributed around the pool. It is important to follow the instructions on the packaging when applying to coloured marble or printed vinyl liners. It can be used on concrete, fibreglass or vinyl liner pools. Use as an all over treatment for stain removal or as a spot treatment. 1kg will treat up to 15,000 gallons. For the removal of coloured metal stains on swimming pool surfaces Multi-stain remover contains a special blend of three organic acids The product has been specifically developed to remove coloured stains (copper, iron and manganese) from swimming pool surfaces Use 1kg of granules per 50,000 litres (11000 gallons) o . Uses: Swimming pools, hot tubs. Maintenance. Grades: A+. Product ID: 5060220113381. MPN: DBPRCH098S. Brand: Deep Blue Pro. Categories: Pool Chemicals. |  Lincolnshire, Wiltshire, Online |
| 1kg Deep Blue Pro Pool Multi Stain Remover - Box of 6 | Deep Blue Pro Multi-Stain Remover Granules are used for the removal of coloured metal stains on swimming pool surfaces. The product contains a special blend of three organic acids and has been specifically developed to remove coloured stains (copper, iron and manganese) from swimming pool surfaces. Product may be sprinkled directly over the stained areas or evenly distributed around the pool. It is important to follow the instructions on the packaging when applying to coloured marble or printed vinyl liners. It can be used on concrete, fibreglass or vinyl liner pools. Use as an all over treatment for stain removal or as a spot treatment. 1kg will treat up to 15,000 gallons. For the removal of coloured metal stains on swimming pool surfaces Multi-stain remover contains a special blend of three organic acids The product has been specifically developed to remove coloured stains (copper, iron and manganese) from swimming pool surfaces Use 1kg of granules per 50,000 litres (11000 gallons) o . Uses: Swimming pools, hot tubs. Maintenance. Grades: A+. Product ID: 5060220113374. MPN: DBPRCH098. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| 1 Litre Deep Blue Pro Pool Leak Sealer | Leak Sealer - 1 litre - For minor leaks in swimming pools and spas. This leak sealer remains the professionals ; favourite. Its special formula can seal small holes/leaks in hot tub & swimming pool pipework & swimming pool 'liners'. It CANNOT be guaranteed to fix 'every leak' but it is remarkable nevertheless and if you call out a repair company they will more than probably try this product first anyway! Save a fortune and do it yourself. This bottle will treat up to 60,000 litres of water. Directions for Use 1) Turn pool pump off. Remove any automatic pool cleaner from the pool. 2) Set the filter on By-pass or re-circulate setting. If neither of these settings are available then remove the filter grids or cartridges from the filter prior to commencing treatment. 3) Leak Sealer should be added to the pool at the rate of 1 litre per 60,000 litres of pool water. There are two methods of application depending on the location of the leak. A) Leak in pool walls or floor - add the leak . Uses: Swimming pools, hot tubs. Maintenance. Grades: A+. Product ID: 5060220113237. MPN: DBPRCH102S. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| 1 Litre Deep Blue Pro Pool Leak Sealer - Box of 6 | Leak Sealer - 1 litre - For minor leaks in swimming pools and spas. This leak sealer remains the professionals ; favourite. Its special formula can seal small holes/leaks in hot tub & swimming pool pipework & swimming pool 'liners'. It CANNOT be guaranteed to fix 'every leak' but it is remarkable nevertheless and if you call out a repair company they will more than probably try this product first anyway! Save a fortune and do it yourself. This bottle will treat up to 60,000 litres of water. Directions for Use 1) Turn pool pump off. Remove any automatic pool cleaner from the pool. 2) Set the filter on By-pass or re-circulate setting. If neither of these settings are available then remove the filter grids or cartridges from the filter prior to commencing treatment. 3) Leak Sealer should be added to the pool at the rate of 1 litre per 60,000 litres of pool water. There are two methods of application depending on the location of the leak. A) Leak in pool walls or floor - add the leak . Uses: Swimming pools, hot tubs. Maintenance. Grades: A+. Product ID: 5060220113220. MPN: DBPRCH102. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| 1-Methylpyridin-1-ium-2-carboxamide | 1-Methylpyridin-1-ium-2-carboxamide is an impurity of Pralidoxime Chloride, a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Group: Pharmaceutical. CAS No. 45750-74-1. Pack Sizes: 100 mg. Product ID: B0157-284893. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 1-methylpyridin-1-ium-2-carboxamide chloride | An impurity of Pralidoxime Chloride. Pralidoxime Chloride is a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Group: Pharmaceutical. CAS No. 21032-31-5. Pack Sizes: 5 mg. Product ID: B2694-338837. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 1-methylpyridin-1-ium-2-carboxamide iodide | An impurity of Pralidoxime Chloride. Pralidoxime Chloride is a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Group: Pharmaceutical. CAS No. 3861-69-6. Pack Sizes: 5 mg. Product ID: B2694-338836. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 1-methylpyridin-1-ium-2-carboxylic acid | 1-methylpyridin-1-ium-2-carboxylic acid is an impurity of Pralidoxime Chloride, a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Group: Pharmaceutical. CAS No. 3697-38-9. Pack Sizes: 100 mg. Product ID: B0157-131635. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5,10,15,20-tetrakis(4-aminophenyl)porphyrinatozinc(II) | 5,10,15,20-tetrakis(4-aminophenyl)porphyrinatozinc(II), a porphyrin-derived molecule, has garnered significant scientific interest due to its potential in anticancer therapies. The compounds photochemical properties may be aptly harnessed for photodynamic therapy, effectively shrinking tumors. Moreover, the compounds antioxidant attributes have garnered considerable attention, creating a possibility for treatment of oxidative stress-inflicted ailments. Recent studies have induced optimism for the compounds use in co-treatments, in combination with frontline therapy drugs to better combat cancer. Group: Pharmaceutical. CAS No. 67595-98-6. Pack Sizes: 10 mg. Product ID: B2708-285096. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AcetaMide,N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl) | 3-Acetylaminophthalic Anhydride is used in the synthesis of Apremilast, a potent phosphodiesterase 4 and tumor necrosis Factor-α inhibitor used in the treatment of psoriatic arthritis. Also a reagent in the preparation of Tillivalline. Group: Pharmaceutical. CAS No. 6296-53-3. Pack Sizes: 1mg; 1g; 10g. Product ID: 6296-53-3. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aclacinomycin | Aclacinomycin is an anthracycline drug that is used in the treatment of cancer. Group: Pharmaceutical. CAS No. 66676-88-8. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-05896. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aclarubicin A | Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. It intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. It is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. It has potent antineoplastic activity. It is used in the treatment of cancer. It can induce histone eviction from chromatin upon intercalation. It has been listed. Uses: Aclarubicin has potent antineoplastic activity. it is used in the treatment of cancer. it can induce histone eviction from chromatin upon intercalation. Group: Pharmaceutical. CAS No. 57576-44-0. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-00542. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acotiamide | Acotiamide is a potent and seletive inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Group: Pharmaceutical. CAS No. 185106-16-5. Pack Sizes: 100 mg. Product ID: B0084-284892. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acotiamide-[d4] | Labelled Acotiamide. Acotiamide is a potent and selective inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003215. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acotiamide-[d6] | Labelled Acotiamide. Acotiamide is a potent and selective inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003216. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aegeline Impurities | Aegeline Impurities are component entities within Aegeline-derived compounds, mainly used in pharmaceutical research to evaluate the quality and efficacy of synthesized drugs. These impurities are crucial for ensuring drug safety and efficacy, particularly in treatments targeting metabolic disorders such as obesity and diabetes-related complications. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afoxolaner | Afoxolaner is a potent isoxazoline insecticide and acaricide against Ixodes scapularis in dogs. It is indicated for the treatment and prevention of flea infestations, and the treatment and control of tick infestations in dogs and puppies. It is administered orally in meat-flavoured tablets, and poisons fleas once they start feeding. It is used either alone or as a combination treatment with milbemycin oxime. Group: Pharmaceutical. CAS No. 1093861-60-9. Pack Sizes: 100 mg. Product ID: B2692-475054. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ARV-825 | ARV-825 is a BRD4 inhibitor based on PROTAC technology. ARV-825 recruits BRD4 to E3 ubiquitin ligase cereblon, resulting in the degradation of BRD4. In post-myeloproliferative neoplasm secondary (s) AML cell lines, treatment with ARV-825 induces apoptosis and inhibits cell proliferation. Group: Pharmaceutical. CAS No. 1818885-28-7. Pack Sizes: 100 mg. Product ID: B1370-474664. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AS 1842856 | AS 1842856 is a potent and selective inhibitor of Forkhead box protein O1 transcription factor (FoxO1; IC50 = 33 nM). AS 1842856 reduces glucose production in dose manner via the inhibition of glucose-6 phosphatase and phosphoenolpyruvate carboxykinase mRNA levels in a rat hepatic cell line. AS 1842856 is promisingly to be a therapy of type 2 diabetes mellitus and obesity. Uses: Potential treatment of type 2 diabetes mellitus and obesity. Group: Pharmaceutical. CAS No. 836620-48-5. Pack Sizes: 200 mg. Product ID: B1370-054875. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Asimadoline | Asimadoline is a κ opioid receptor agonist with less brain-penetrant ability. Asimadoline is the potential treatment of irritable bowel syndrome. Group: Pharmaceutical. CAS No. 153205-46-0. Pack Sizes: 50 mg. Product ID: B0084-071264. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BAY-1895344 | BAY-1895344 is a selective ATR (ataxia-telangiectasia and Rad3 related protein) inhibitor that inhibits proliferation of a broad spectrum of human tumor cell lines (median IC50 = 78 nM). BAY-1895344 is developed for the treatment of patients with advanced solid tumors and lymphomas, and it is undergoing a phase I clinical trial of safety and tolerability for cancer patients. Uses: A selective atr (ataxia-telangiectasia and rad3 related protein) inhibitor used for the treatment of advanced solid tumors and lymphomas. Group: Pharmaceutical. CAS No. 1876467-74-1. Pack Sizes: 10 mg. Product ID: B0084-484682. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Benzhexol Impurities | Benzhexol Impurities hold pivotal importance in the biomedical sector, facilitating rigorous quality assurance and pharmacokinetic assessments of anticholinergic drugs, such as trihexyphenidyl. These impurities are integral to ensuring the efficacy and safety of treatments for Parkinsons and extrapyramidal disorders, optimizing therapeutic strategies and elevating patient care standards. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chlorambucil | Chlorambucil (marketed as Leukeran by GlaxoSmithKline) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. It is a nitrogen mustard alkylating agent and can be given orally. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. Group: Pharmaceutical. CAS No. 305-03-3. Pack Sizes: 5 g. Product ID: B1370-065622. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chrysophanol | Chrysophanic acid (Chrysophanol) is a natural anthraquinone with anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells. Chrysophanic acid preferentially blocked proliferation in SNU-C5 cells but not in other cell lines (HT7, HT29, KM12C, SW480, HCT116 and SNU-C4) with low levels of EGFR expression. Chrysophanic acid treatment in SNU-C5 cells inhibited EGF-induced phosphorylation of EGFR and suppressed activation of downstream signaling molecules, such as AKT, extracellular signal-regulated kinase (ERK) and the mammalian target of rapamycin (mTOR)/ribosomal protein S6 kinase (p70S6K). Chrysophanic acid (80 and 120 μm) significantly blocked cell proliferation when combined with the mTOR inhibitor, rapamycin. These findings offer the first evidence of anticancer activity for chrysophanic acid via EGFR/mTOR mediated signaling transduction pathway. Chrysophanol is a natural compound found in the roots and rhizomes of Rheum palmatum L. It can be used in cosmetics material. Uses: Anti-inflammatory. Group: Pharmaceutical. CAS No. 481-74-3. Pack Sizes: 1 g. Product ID: NP0901. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cirsimaritin | Cirsimaritin is purified from the herbs of Microtea debilis. Cirsimaritin has the potential use in patients with congestive heart failure that can mitigate cardiac remodeling and left ventricular dysfunction through augmenting myocardial autophagy and decreasing matrix metalloproteinase-2&9 activities. Cirsimaritin inhibits the growth of tumor cells and induces mitochondrial apoptosis in human gallbladder carcinoma cell line (GBC-SD), and it triggers endoplasmic reticulum (ER) stress and down-regulates the phosphorylation of Akt. Cirsimaritin shows moderate anti-proliferative activity against COLO-205 cells with IC 50 values of 13.1uM. Cirsimaritin increases tyrosinase activity and melanin content in murine B16F10 melanoma cells by activation of CREB as well as upregulation of MITF and tyrosinase expression in a dose-dependent manner; support the putative application of cirsimaritin in ultraviolet photoprotection and hair coloration treatments. Group: Pharmaceutical. CAS No. 6601-62-3. Pack Sizes: 5 mg. Product ID: NP2021. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Daunorubicinol hydrochloride | Daunorubicinol Hydrochloride is a metabolite of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Group: Pharmaceutical. CAS No. 28008-53-9. Pack Sizes: 2.5 mg. Product ID: B0709-004063. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Deep Blue Pro 20 litres (4 x 5 Litres) Micro-Cide swimming pool hot tub | Deep Blue Pro Pool & Spa Micro-CideDeep Blue Pro Pool & Spa Micro-Cide - This is a 2 part non-chlorine system ideal for inground, above ground & spa ;s. Simply add both parts to your pool for crystal clear water without chlorine.This Micro-Cide liquid is a concentrated microbiocide.Deep Blue Pro Micro-Cide should be used in conjunction with Deep Blue Pro Oxygen-Tab and and ideally a high quality clarifier such as Deep Blue Pro pool tub Clarifier. Directions for use:Initial Treatment:Add 700ml of Deep Blue Pro micro-cide per 45,500 Litres or 10,000 Gallons Maintenance Treatment:Add 250ml of Deep Blue Pro micro-cide per 45,500 Litres or 10,000 Gallons weekly.This micro-cide should be added in conjunction with the Deep Blue Pro oxygen tablets.This product should be put into the water as close as possible to the return inlets to aid dispersment.The initial treatment should be repeated whenever the water starts to look slightly cloudy.This dose is merely meant as a guideline and . Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Product ID: 5060220076112. MPN: DBPRCH048. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro 5 litres Relax Micro-Cide 5L 5litres swimming pool hot tub | Deep Blue Pro Pool & Spa Micro-CideDeep Blue Pro Pool & Spa Micro-Cide - This is a 2 part non-chlorine system ideal for inground, above ground & spa ;s. Simply add both parts to your pool for crystal clear water without chlorine.This Micro-Cide liquid is a concentrated microbiocide.Deep Blue Pro Micro-Cide should be used in conjunction with Deep Blue Pro Oxygen-Tab and and ideally a high quality clarifier such as Deep Blue Pro pool tub Clarifier. Directions for use:Initial Treatment:Add 700ml of Deep Blue Pro micro-cide per 45,500 Litres or 10,000 Gallons Maintenance Treatment:Add 250ml of Deep Blue Pro micro-cide per 45,500 Litres or 10,000 Gallons weekly.This micro-cide should be added in conjunction with the Deep Blue Pro oxygen tablets.This product should be put into the water as close as possible to the return inlets to aid dispersment.The initial treatment should be repeated whenever the water starts to look slightly cloudy.This dose is merely meant as a guideline and . Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Product ID: 0666186536483. MPN: DBPRCH048S. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Defluoro Linezolid | Defluoro Linezolid is an impurity of Linezolid, which is an antibiotic used for the treatment of infections caused by Gram-positive bacteria. Group: Pharmaceutical. CAS No. 556801-15-1. Pack Sizes: 100 mg. Product ID: B2694-472430. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Diphemanil Impurities | Diphemanil Impurities, found in pharmaceutical analysis, are essential for the quality control of Diphemanil Methylsulfate, an anticholinergic medication. Used primarily to manage peptic ulcers and reduce gastric secretions, analyzing these impurities ensures drug stability, safety, and efficacy in the treatment of gastrointestinal disorders. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Donepezil | Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to severe Alzheimer's disease. It readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Group: Pharmaceutical. CAS No. 120014-06-4. Pack Sizes: 50 g. Product ID: B2692-082304. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Dovitinib | Dovitinib (TKI258) potently inhibited FLT3, c-KIT, FGFR, VEGFR1/2/3, PDGFRß and CSF-1R with IC50 values of 1, 2, 5, 10, 8, 27, 36 nM respectively. Dovitinib selectively blocked the growth of wild-type (WT) or activated mutant FGFR3-transformed B9 cells and human myeloma cell lines. Dovitinib was an effective treatment in a xenograft mouse model of FGFR3 multiple myeloma. Group: Pharmaceutical. CAS No. 405169-16-6. Pack Sizes: 50 mg. Product ID: B2693-091881. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Doxofylline Impurities | Doxofylline Impurities play a crucial role in the biomedical industry by ensuring the purity and safety of doxofylline formulations, a drug used primarily for the treatment of chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). These impurities are essential for assessing drug quality and efficacy. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Doxycycline EP Impurity F | Doxycycline EP Impurity F is an impurity of Doxycycline, which is a semisynthetic, broad-spectrum tetracycline antibiotic used in the treatment of infections caused by bacteria and certain parasites. Group: Pharmaceutical. CAS No. 122861-53-4. Pack Sizes: 2 mg. Product ID: B2694-470498. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Epirubicin hydrochloride Impurities | Epirubicin hydrochloride Impurities function as essential analytical entities within the biomedical sector, facilitating the evaluation of epirubicin's purity and stability. As an anthracycline antibiotic primarily utilized for breast cancer treatment, these impurities are instrumental in advancing chemotherapeutic development, ensuring enhanced efficacy and safety parameters. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Escitalopram | Escitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of escitalopram is found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Escitalopram does not inhibit monoamine oxidase. Uses: Serotonin uptake inhibitors; antidepressive agents, second-generation. Group: Pharmaceutical. CAS No. 128196-01-0. Pack Sizes: 500 mg. Product ID: B2693-461840. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Fmoc-3,4-dehydro-L-proline | Fmoc-3,4-dehydro-L-proline, a chemical intermediary employed in the synthesis of peptides within the biomedical sector, displays considerable promise with regard to the treatment of conditions such as cancer and Alzheimer's disease. Its potential medical applications are extensive and merit further exploration. Group: Pharmaceutical. CAS No. 135837-63-7. Pack Sizes: 1 g. Product ID: BAT-007331. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Galanthamine | Galanthamine, also called Razadyne, found in GALANTHUS and other AMARYLLIDACEAE, a cholinesterase inhibitor prescribed to treat symptoms of mild to moderate Alzheimer's, enhances cholinergic function accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Uses: Treatment of alzheimer's disease. Group: Pharmaceutical. CAS No. 357-70-0. Pack Sizes: 1 g. Product ID: B1370-343377. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ganoderiol F | Lansiumarin C is a natural coumarin found in the branches of Clausena lansium. and found to induce senescence of cancer cell lines, it induces growth arrest of cancer cell lines HepG2, Huh7 and K562; activation of the mitogen-activated protein kinase EKR and up-regulation of cyclin-dependent kinase inhibitor p16 were found in early stages of Ganoderiol F treatment and were presumed to cause cell-cycle arrest and trigger premature senescence of HepG2 cells; suggests that the growth-arrest and senescence induction capability on cancer cells suggest anticancer potential of Ganoderiol F. It could be developed further as both anti-HIV and antimalaria.In Compared to plasmepsin I, ganoderiol-F is higher towards HIV-1 protease. Uses: Anti-inflammatory; anti-hiv. Group: Pharmaceutical. CAS No. 114567-47-4. Pack Sizes: 1 mg. Product ID: NP6829. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glabredelphinine | Glabredelphinine, a naturally occurring substance, has garnered attention for its remarkable efficacy in inducing apoptosis in tumors, thus displaying its potent anti-tumor activity. Furthermore, it has exhibited potential therapeutic benefits in the treatment of Alzheimer's disease by impeding acetylcholinesterase activity. Through its multifaceted mechanisms, Glabredelphinine represents an intriguing candidate for further exploration within both oncological and neurological research domains. Group: Pharmaceutical. CAS No. 132160-37-3. Pack Sizes: 1 mg. Product ID: NP0658. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Idarubicinone | Idarubicinone is a derivative of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Group: Pharmaceutical. CAS No. 60660-75-5. Pack Sizes: 5 mg. Product ID: B0709-003996. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ipidacrine hydrochloride hydrate | Ipidacrine is a drug used for the treatment of memory disorders. It acts as a reversible acetylcholinesterase inhibitor. Group: Pharmaceutical. CAS No. 118499-70-0. Pack Sizes: 1 g. Product ID: B0046-013871. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isoprenaline HCl EP Impurity A | An impurity of Isoprenaline, a medication used for the treatment of bradycardia, heart block, and rarely for asthma. Group: Pharmaceutical. CAS No. 16899-81-3. Pack Sizes: 25 mg. Product ID: B1370-132332. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isoprenaline hydrochloride | Isoprenaline is a non-selective beta-adrenergic receptor agonist, used for the treatment of bradycardia and heart block. It would increase cAMP levels and activate protein kinase A and ERK1/2 through its effect on β-adrenoceptor. Uses: The treatment of bradycardia and heart block. Group: Pharmaceutical. CAS No. 51-30-9. Pack Sizes: 50 g. Product ID: NP3260. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ku-0063794 | KU-0063794 is an inhibitor of both mTORC1 and mTORC2 with an IC50 of approximately 10 nM, but does not suppress the activity of 76 other protein kinases or seven lipid kinases, including Class 1 PI3Ks (phosphoinositide 3-kinases) at 1000-fold higher concentrations. KU-0063794 is cell permeant, suppresses activation and hydrophobic motif phosphorylation of Akt, S6K and SGK, but not RSK (ribosomal S6 kinase), an AGC kinase not regulated by mTOR. It also inhibited phosphorylation of the T-loop Thr308 residue of Akt phosphorylated by PDK1 (3-phosphoinositide-dependent protein kinase-1). It does not affect Thr308 phosphorylation in fibroblasts lacking essential mTORC2 subunits. KU-0063794 also suppressed cell growth and induced a G1-cell-cycle arrest. KU-0063794 will be useful in delineating the physiological roles of mTOR and may have utility in treatment of cancers in which this pathway is inappropriately activated. Uses: Differentiation. Group: Pharmaceutical. CAS No. 938440-64-3. Pack Sizes: 100 mg. Product ID: B0084-100850. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lobeline Impurities | Lobeline Impurities are crucial in the development and quality control of pharmaceuticals targeting neurological disorders, particularly those focusing on nicotine addiction and respiratory diseases. These impurities help ensure the purity and efficacy of lobeline-based drugs, thereby advancing therapeutic research and enhancing treatment protocols for associated conditions. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Macitentan Impurities | Macitentan Impurities, as crucial analytical instruments, contribute deeply to pharmacokinetics and safety evaluation in biomedical research. Their role encompasses delineating drug metabolism and verifying macitentan's therapeutic effectiveness and safety, pivotal in enhancing pulmonary arterial hypertension (PAH) treatments and informing the strategic development of PAH interventions. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Methiocarb Impurities | Methiocarb Impurities, essential in pharmaceutical analytics, underpin the innovation and validation processes for anticholinergic medications. Through detailed examination, they guarantee therapeutic uniformity for ailments like Parkinsons disease and overactive bladder, diligently eradicating superfluous byproducts, hence enhancing drug dependability and elevating patient treatment effectiveness. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ML241 | ML241 is a selective p97 ATPase inhibitor and IC50 value is 100 nM. It can inhibit degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ML241 may be a novel agent for the treatment of cancer. Uses: Anticancer. Group: Pharmaceutical. CAS No. 1346528-06-0. Pack Sizes: 100 mg. Product ID: B0084-475332. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mubritinib | Mubritinib, also known as TAK-165, is a protein kinase inhibitor which was under development by Takeda for the treatment of cancer. It completed phase I clinical trials (may be discontinued since 2008). Mubritinib(TAK 165) is a potent EGFR, HER2 and p34cdc2 inhibitor with IC50 of 6 nM and 0.2 μM, respectively. Mubritinib(TAK 165) also inhibits p33cdk2 and p33cdk5. Mubritinib(TAK 165) displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. Mubritinib(TAK 165) exhibits potent antiproliferative effects in ErbB2-overexpressing cancer cell lines (IC50 = 5 nM in BT474 breast cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth in vivo. Group: Pharmaceutical. CAS No. 366017-09-6. Pack Sizes: 50 mg. Product ID: B0084-067201. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Boc-1,2,3,6-tetrahydropyridine-4-boronic Acid Pinacol Ester | Reagent used for : Suzuki-Miyaura cross-coupling using palladium phosphine catalyst ; Palladium-catalyzed ligand-controlled regioselective Suzuki coupling ; Palladium-catalyzed Suzuki-Miyaura coupling ; Suzuki coupling followed by iodolactonization reaction ; Wrenchnolol derivative optimized for gene activation in cells Reagent used in Preparation of several enzymatic inhibitors and receptor ligands; Orally active anaplastic lymphoma kinase inhibitors ; Oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes ; 4-arylpiperidinyl amides and N-arylpiperidin-3-yl-cyclopropanecarboxamides as novel melatonin receptor ligands ; Quinazoline analogs as glucocerebrosidase inhibitors with chaperone activity for treatment of Gaucher disease, a lysosomal storage disorder ; Arylpiperazine and piperidine ethers as dual acting norepinephrine reuptake inhibitors and 5-HT1A partial agonists. Group: Pharmaceutical. CAS No. 286961-14-6. Pack Sizes: 100 g. Product ID: BB019917. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Neratinib | Neratinib, also known as HKI-272 or PB272, is an orally available, 6,7-disubstituted-4-anilinoquinoline-3-carbonitrile irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER-2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP-binding pocket of the receptor. Treatment of cells with this agent results in inhibition of downstream signal transduction events and cell cycle regulatory pathways; arrest at the G1-S (Gap 1/DNA synthesis)-phase transition of the cell division cycle; and ultimately decreased cellular proliferation. Neratinib also inhibits the epidermal growth factor receptor (EGFR) kinase and the proliferation of EGFR-dependent cells. Group: Pharmaceutical. CAS No. 698387-09-6. Pack Sizes: 500 mg. Product ID: B0084-347125. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Nitenpyram | Nitenpyram, a natural product found in Streptomyces canus, is a nicotinic acetylcholine receptor (AchR) agonist used in veterinary medicine to treat parasites of livestock and pets. Uses: The treatment of parasites. Group: Pharmaceutical. CAS No. 150824-47-8. Pack Sizes: 10 g. Product ID: BBF-05823. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Norhyoscyamine sulfate | Norhyoscyamine sulfate, a potent anticholinergic agent, exerts its therapeutic effects through the inhibition of acetylcholine activity, which makes it a valuable treatment option for several types of gastrointestinal disorders, such as motility disorders, as well as urinary incontinence. Moreover, this multifaceted medication exhibits remarkable preoperative benefits, as it can effectively reduce both respiratory and digestive secretions, underscoring its versatility and potential for widespread clinical use. Group: Pharmaceutical. CAS No. 537-29-1. Pack Sizes: 100 mg. Product ID: B1370-152647. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| NSI-189 | NSI-189 is an experimental drug being studied by Neuralstem, Inc. Research into NSI-189 has been funded by the Defense Advanced Research Projects Agency (DARPA) and the National Institutes of Health (NIH) for the treatment of major depressive disorder. NSI-189 successfully completed a phase 1 clinical trial in 2011 where it was administered to 41 healthy volunteers. A phase 1b clinical trial for treating major depressive disorder in 24 patients started in 2012 and completed in July 2014. The study suggests that there were improvements in the patients' condition when the doses were 40/80 mg per day, but no significant improvements were seen for a higher dosage of 120 mg/day. Neuralstem intends to pursue further clinical trials for a variety of neurological conditions, including major depressive disorder, traumatic brain injury, Alzheimer's disease, post-traumatic stress disorder, stroke, and natural cognitive and memory decline in aging. Uses: For research used only. Group: Pharmaceutical. CAS No. 1270138-40-3. Pack Sizes: 5 g. Product ID: B0084-462290. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Oxytetracycline EP Impurity C | Oxytetracycline EP Impurity C is an impurity of Oxytetracycline, which is a broad-spectrum tetracycline antibiotic used for the treatment of various infectious diseases, like anthrax, Chlamydia, cholera, typhus, relapsing fever, malaria, plaque, syphilis, respiratory infection, streptococcal infection, and acne. Group: Pharmaceutical. CAS No. 7647-65-6. Pack Sizes: 1 mg. Product ID: B2694-072460. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Oxytetracycline Impurities | Oxytetracycline Impurities, as critical components in pharmaceutical investigations, fortify quality control protocols and efficacy assessments of oxytetracycline antibiotic formulations. By enabling exact identification and quantification, they uphold therapeutic integrity, ensuring treatments for bacterial infections, such as pneumonia and urinary tract infections, conform to elevated antimicrobial criteria. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Parecoxib Impurity 1 | An impurity of Parecoxib. The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue. Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision. Group: Pharmaceutical. CAS No. 1708094-99-8. Pack Sizes: 5 mg. Product ID: B2694-338806. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Parecoxib Impurity 24 | An impurity of Parecoxib. The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue. Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision. Group: Pharmaceutical. CAS No. 198470-82-5. Pack Sizes: 5 mg. Product ID: B2694-338807. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Potassium Permanganate | Potassium permanganate is a purple-coloured crystalline salt with the chemical formula KMnO4. Also known as Condy's crystals or permanganate of potash, the compound is a strong oxidising agent that dissolves easily in water. Potassium permanganate is used to treat a variety of skin conditions, including fungal foot infections. Despite its medical benefits, it's considered a hazardous substance in high concentrations and may cause eye and skin damage. Uses: Water treatment, food preservation. Group: Laboratory Chemicals. Alternative Names: Potassium Salt. CAS No. 7722-64-7. Pack Sizes: 2.5L. | Chemicals.co.uk |
| rac-N-Desmethyl Bedaquiline | rac-N-Desmethyl Bedaquiline is an intermediate used in th synthesis of Bedaquiline, a medication approved for the treatment of active tuberculosis. Group: Pharmaceutical. CAS No. 654654-76-9. Pack Sizes: 1 g. Product ID: B2692-007095. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rasagiline Impurities | Rasagiline Impurities, integral to pharmaceutical quality assurance, are pivotal in the drug development lifecycle for Parkinson's treatment. Through comprehensive analysis of these impurities, insights into the medication's stability, efficacy, and safety are gleaned, ensuring adherence to rigorous pharmaceutical standards and safeguarding therapeutic reliability. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rivastigmine-[d6] oxalate | Rivastigmine-[d6] oxalate is a labelled impurity of Rivastigmine. Rivastigmine is a parasympathomimetic or cholinergic drug for the treatment of dementia. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: BLP-014089. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (R)-Linezolid | (R)-Linezolid is an enatiomeric impurity of Linezolid, an antibiotic used for the treatment of infections caused by Gram-positive bacteria. Group: Pharmaceutical. CAS No. 872992-20-6. Pack Sizes: 1 g. Product ID: B1370-472432. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SB742457 | SB742457 is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects.It was under development by GlaxoSmithKline for the treatment of Alzheimer's disease. Group: Pharmaceutical. CAS No. 607742-69-8. Pack Sizes: 50 mg. Product ID: B0084-404961. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SCH772984 | SCH772984 is a potent and selective ERK inhibitor with potential anticancer activity. SCH722984 showed activity against BRAF mutant, NRAS mutant and wild-type melanoma. Combining vemurafenib and SCH722984 in BRAF mutant melanoma was synergistic in a majority of cell lines and significantly delayed the onset of acquired resistance in long term in vitro assays. Therefore, SCH772984 may be clinically applicable as a treatment for non-BRAF mutant melanoma or in BRAF-mutant melanoma with innate or acquired resistance, alone or in combination with BRAF inhibitors. Group: Pharmaceutical. CAS No. 942183-80-4. Pack Sizes: 25 mg. Product ID: B2693-429803. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sertraline 2,3-Dichloro Ketone Impurity | An impurity of sertraline. Sertraline is a selective serotonin reuptake inhibitor (SSRI) for the treatment of depression. Group: Pharmaceutical. CAS No. 152448-80-1. Pack Sizes: 200 mg. Product ID: B0186-260624. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sodium Metabisulphite | Sodium Metabisulphite is a white crystalline powder also known as European food additive number E223. To request a quote or for more information on this product visit the Monarch Chemicals website. Uses: Food and Drink, Textiles, Water Treatment, Processing Chemicals. Group: Sodiums. Alternative Names: E223, Sodium Metabisulfite. Pack Sizes: Pallet 25Kg Bags. |  United Kingdom |
| Tacrine Impurities | Tacrine Impurities are crucial in the development and quality control of Alzheimer's disease treatments. Studying these impurities aids in enhancing the safety and efficacy of tacrine, an acetylcholinesterase inhibitor, crucial for symptom management in Alzheimer's, thus advancing therapeutic methods for neurodegenerative disorders. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| TAS-102 | TAS-102 is a combination drug composed of the cytotoxic pyrimidine analog Trifluridine (5-trifluoro-2'-deoxythymidine or TFT) and a thymidine phosphorylase inhibitor (TPI) tipiracil hydrochloride, in a molar ratio of 1.0:0.5 (TFT:TPI). TAS-102 is used as a third- or fourth-line treatment of metastatic colorectal cancer. Group: Pharmaceutical. CAS No. 733030-01-8. Pack Sizes: 50 mg. Product ID: B0046-462799. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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