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2-[3-(R)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol is an intermediate in the synthesis of Montelukast, which is a leukotriene receptor antagonist indicated for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Group: Pharmaceutical. Alternative Names: (R)-α-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)benzenepropanol; (1R)-1-{3-[(E)-2-(7-Chloro-2-quinoleinyl)vinyl]phenyl}-3-[2-(2-hydroxy-2-propanyl)phenyl]-1-propanol; Benzenepropanol, α-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)-, (αR)-; (R,E)-1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propan-1-ol. CAS No. 150026-75-8. Pack Sizes: 100 mg. Product ID: B0052-208484. Molecular formula: C29H28ClNO2. Mole weight: 457.99. Custom synthesis is available. Send your inquiries for more information.
2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol is a montelukast impurity, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: A montelukast impurity. Group: Pharmaceutical. Alternative Names: Montelukast Diene; Montelukast Diol Impurity; Montelukast (3S)-Hydroxy Propanol; 2-[2-[3(S)-[3-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl-2-propanol. CAS No. 287930-77-2. Pack Sizes: 100 mg. Product ID: B1370-118426. Molecular formula: C29H28ClNO2. Mole weight: 457.99. Custom synthesis is available. Send your inquiries for more information.
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Ablukast
Ablukast, a specific and active leukotriene receptor antagonist, effectively reduces LTC4- and antigen-induced bronchoconstriction. It is an LTD4 receptor antagonist with anti-asthmatic effect. Group: Pharmaceutical. Alternative Names: Ro 23-3544; 6-Acetyl-7-(5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyloxy)-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid; 2H-1-Benzopyran-2-carboxylic acid, 6-acetyl-7-((5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl)oxy)-3,4-dihydro-, (±)-. CAS No. 96566-25-5. Pack Sizes: 1mg;1g;10g. Product ID: 96566-25-5. Molecular formula: C28H34O8. Mole weight: 498.56. Custom synthesis is available. Send your inquiries for more information.
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ABT-080
ABT-080 is a leukotriene synthesis inhibitor potentially for the treatment of asthma. Group: Pharmaceutical. Alternative Names: Benzenebutanoic acid, γ-methyl-4-(2-quinolinylmethoxy)-γ-[4-(2-quinolinylmethoxy)phenyl]-, sodium salt (1:1); Benzenebutanoic acid, γ-methyl-4-(2-quinolinylmethoxy)-γ-[4-(2-quinolinylmethoxy)phenyl]-, monosodium salt; 4,4-bis(4-(2-quinolylmethoxy)phenyl)pentanoic acid sodium salt; ABT 080; ABT080; VML 530; VML530; VML-530. CAS No. 189498-57-5. Pack Sizes: 1mg;1g;10g. Product ID: 189498-57-5. Molecular formula: C37H31N2NaO4. Mole weight: 590.64. Custom synthesis is available. Send your inquiries for more information.
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Acebilustat
Acebilustat, formerly known as ZK322, is an oral anti-inflammatory designed to reduce the production of leukotriene B4 (LTB4). Group: Pharmaceutical. Alternative Names: 4-(((1S,4S)-5-(4-(4-(oxazol-2-yl)phenoxy)benzyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)methyl)benzoic acid; ZK322; ZK-322; ZK 322; CTX-4430; EP-501; CTX4430; EP501; CTX 4430; EP 501; Acebilustat, CAS#943764-99-6. CAS No. 943764-99-6. Pack Sizes: 100 mg. Product ID: B0084-007834. Molecular formula: C29H27N3O4. Mole weight: 481.55. Custom synthesis is available. Send your inquiries for more information.
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Bestatin
Bestatin is a specific aminopeptidase B inhibitor produced by Streptomyces olivoreticuli. Bestatin is a potent aminopeptidase-B and leukotriene (LT) A4 hydrolase inhibitor used in the treatment of acute myelocytic leukemia. It exhibits potential immunomodulatory and antitumor activities. Uses: The treatment of acute myelocytic leukemia. Group: Pharmaceutical. Alternative Names: Ubenimex. CAS No. 58970-76-6. Pack Sizes: 1 g. Product ID: BAT-015664. Molecular formula: C16H24N2O4. Mole weight: 308.37. Custom synthesis is available. Send your inquiries for more information.
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Cilastatin Ammonium Salt
Cilastatin Ammonium Salt is the ammonium salt of Cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. Group: Pharmaceutical. Alternative Names: (2Z)-7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic Acid Ammonium Salt; MK-791 Ammonium Salt. CAS No. 877674-82-3. Pack Sizes: 500 mg. Product ID: B2693-468925. Molecular formula: C16H29N3O5S. Mole weight: 375.48. Custom synthesis is available. Send your inquiries for more information.
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Cilastatin sodium
Cilastatin sodium is the sodium salt of cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. Group: Pharmaceutical. Alternative Names: L 642957; MK 791; L642957; MK791; L-642957; MK-791; [R-[R*,S*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic Acid Monosodium Salt; (2Z)?-7-[[(2R)?-2-Amino-2-carboxyethyl]?thio]?-2-[[[(1S)?-2,?2-dimethylcyclopropyl]?carbonyl]?amino]?-2-heptenoic Acid Sodium Salt; sodium S-((Z)-6-carboxy-6-((S)-2,2-dimethylcyclopropane-1-carboxamido)hex-5-en-1-yl)-L-cysteinate. CAS No. 81129-83-1. Pack Sizes: 1 g. Product ID: B0084-077802. Molecular formula: C16H25N2NaO5S. Mole weight: 380.43. Custom synthesis is available. Send your inquiries for more information.
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Montelukast Dicyclohexylamine Salt
Montelukast is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: A selective leukotriene d4-receptor antagonist. used as an antiasthmatic. Group: Pharmaceutical. Alternative Names: 1-[1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic N-Cyclohexylcyclohexanamine; Montelukast DCHA. CAS No. 577953-88-9. Pack Sizes: 1 g. Product ID: B2692-263088. Molecular formula: C47H59ClN2O3S. Mole weight: 767.5. Custom synthesis is available. Send your inquiries for more information.
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Montelukast EP Impurity D
Montelukast EP Impurity D is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Group: Pharmaceutical. Alternative Names: Montelukast USP Related Compound C; (R,R)-Montelukast Bis-sulfide; 1-[[[(1R)-1-[3-[(1R)-1-[[[1-(Carboxymethyl)cyclopropyl]methyl]thio]-2-(7-chloro-2-quinolinyl)ethyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-cyclopropaneacetic acid. CAS No. 1187586-61-3. Pack Sizes: 25 mg. Product ID: B2694-121121. Molecular formula: C41H46ClNO5S2. Mole weight: 732.39. Custom synthesis is available. Send your inquiries for more information.
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Montelukast EP Impurity E
An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Group: Pharmaceutical. Alternative Names: Montelukast USP Related Compound D; (R,S)-Montelukast Bis-sulfide; Montelukast R,S-Isomer; 2-(1-((((R)-1-(3-((S)-1-(((1-(carboxymethyl)cyclopropyl)methyl)thio)-2-(7-chloroquinolin-2-yl)ethyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetic acid. CAS No. 1187586-58-8. Pack Sizes: 10 mg. Product ID: B2694-477814. Molecular formula: C41H46ClNO5S2. Mole weight: 732.39. Custom synthesis is available. Send your inquiries for more information.
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Montelukast EP Impurity I
An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Group: Pharmaceutical. Alternative Names: alpha hydroxy montelukast; Montelukast metabolite M7; [1-[1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropyl](hydroxy)acetic Acid. CAS No. 2045402-27-3. Pack Sizes: 10 mg. Product ID: B1370-234661. Molecular formula: C35H36ClNO4S. Mole weight: 602.18. Custom synthesis is available. Send your inquiries for more information.
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Montelukast Related Impurity 1
An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Group: Pharmaceutical. Alternative Names: 1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]-1-propanone. CAS No. 1258428-71-5. Pack Sizes: 25 mg. Product ID: B2694-477823. Molecular formula: C29H26ClNO2. Mole weight: 455.99. Custom synthesis is available. Send your inquiries for more information.
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Montelukast Related Impurity 2
An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Group: Pharmaceutical. Alternative Names: 2-[3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoic Acid Methyl Ester; Methyl (E)-2-[3-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoate. CAS No. 149968-11-6. Pack Sizes: 100 mg. Product ID: B1361-084543. Molecular formula: C28H22ClNO3. Mole weight: 455.95. Custom synthesis is available. Send your inquiries for more information.
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Montelukast S-Enantiomer Sodium Salt
An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Group: Pharmaceutical. Alternative Names: 1-[[[(1S)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic Acid Sodium Salt; L 768232; Montelukast EP Impurity A. CAS No. 190078-45-6. Pack Sizes: 50 mg. Product ID: B2694-407610. Molecular formula: C35H35ClNO3S.Na. Mole weight: 608.2. Custom synthesis is available. Send your inquiries for more information.
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Montelukast Sodium Salt
Montelukast is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Group: Pharmaceutical. Alternative Names: MK-0476; MK 0476; MK0476. CAS No. 151767-02-1. Pack Sizes: 5 g. Product ID: B0084-059490. Molecular formula: C35H36ClNO3S.Na. Mole weight: 608.17. Custom synthesis is available. Send your inquiries for more information.
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Montelukust Keto Impurity
An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Group: Pharmaceutical. Alternative Names: Montelukast (3S)-Hydroxy Methylketone; [S-(E)]-1-[2-[3-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]ethanone. CAS No. 184764-13-4. Pack Sizes: 100 mg. Product ID: B1370-259898. Molecular formula: C28H24ClNO2. Mole weight: 441.96. Custom synthesis is available. Send your inquiries for more information.
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N, N'-Diacetyl-L-Cystine
N,N'-Diacetyl-L-cystine can be used to treat for dermal imflammations caused by leukotriene production. Group: Pharmaceutical. Alternative Names: N,N'-Diacetyl-L-cystine; (Ac-Cys-OH)2; N,N'-Diacetylcystine; NSC 203780. CAS No. 5545-17-5. Pack Sizes: 1mg;1g;10g. Product ID: BAT-008029. Molecular formula: C10H16N2O6S2. Mole weight: 324.37. Custom synthesis is available. Send your inquiries for more information.
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Osthol
Osthole is a coumarin which is isolated from Cnidium monnieri (L.) Cusson. Osthole is a calcium channel modulator via inhibiting phosphodiesterases. It also regulates the expression of TNF-α, NF-κB, TGF-β, cyclooxygenases, leukotrienes, nitric oxide, ERK, and JNK. Osthole is a natural compound used in cosmetics material. Uses: Anti-tumor; anti-cancer; may be used as bio-pesticides. Group: Pharmaceutical. Alternative Names: Osthol; 7-methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one. CAS No. 484-12-8. Pack Sizes: 100 g. Product ID: NP1032. Molecular formula: C15H16O3. Mole weight: 244.29. Custom synthesis is available. Send your inquiries for more information.
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Roseoside
Roseoside comes from the herbs of Catharanthus roseus. Roseoside has insulinotropic activity, enhances insulin release from the β-cell line INS-1. And it has Inhibitory activity on leukotriene release from mouse bone marrow-derived cultured mast cells (BMCMC). Uses: Insulinotropic activity. Group: Pharmaceutical. Alternative Names: (2R,3E)-4-[(1S)-1-Hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl ]-3-buten-2-yl β-D-glucopyranoside. CAS No. 54835-70-0. Pack Sizes: 1 mg. Product ID: NP5607. Molecular formula: C19H30O8. Mole weight: 386.4. Custom synthesis is available. Send your inquiries for more information.
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Triptinin B
Triptinin B is extracted from the roots of Tripterygium wilfordii Hook.f. It is one of the leukotriene D4 antagonist constituents. Group: Pharmaceutical. Alternative Names: Triptinin B; 189389-05-7; (4aS,10aS)-8-hydroxy-1,4a-dimethyl-7-propan-2-yl-4,9,10,10a-tetrahydro-3H-phenanthrene-2-carboxylic acid. CAS No. 189389-05-7. Pack Sizes: 1 mg. Product ID: NP1410. Molecular formula: C20H26O3. Mole weight: 314.42. Custom synthesis is available. Send your inquiries for more information.
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