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| Product | Description | |
|---|---|---|
| LEAD ACETATE | LEAD ACETATE, Suppliers of UK laboratory chemicals wanted |  |
| LEAD (II) ACETATE | LEAD (II) ACETATE, Suppliers of laboratory chemicals wanted in the United Kingdom | |
| Lead (II) acetate trihydrate | 1kg Pack Size. Group: Inorganic Chemicals, Salts. Formula: C4H6O4Pb · 3H2O. CAS No. 6080-56-4. Prepack ID : 26301277-1kg. Molecular Weight : 379.33. |  |
| Copper Acetate Monohydrate | Copper Acetate Monohydrate A leading independent chemical distributor and agent for Copper Acetate Monohydrate, Chemisphere Limited has all the expertise and knowledge associated with an established chemical distribution company. We supply competitively priced Copper Acetate Monohydrate on demand. |  England, Staffordshire |
| DAPT | DAPT, also called γ-Secretase Inhibitor IX, is a potent and selective inhibitor of γ-secretase which leads to a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (total Aβ: IC50 = 115 nM (human); Aβ42: IC50 = 200 nM (human)). Uses: Differentiation. Group: Pharmaceutical. Alternative Names: tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate; dapt; 208255-80-5; DAPT (GSI-IX); gamma-Secretase Inhibitor IX; CHEBI:86193; MFCD04974585; DAPT, GSI-IX; InSolution gamma-Secretase Inhibitor IX; N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester; N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester(DAP. CAS No. 208255-80-5. Pack Sizes: 50 mg. Product ID: B0084-101748. Molecular formula: C23H26F2N2O4. Mole weight: 432.46. Custom synthesis is available. Send your inquiries for more information. |  London |
| Edetate trisodium | Edetate trisodium, a chelating agent that sequesters and decreases the reactivity of metal ions, is used to treat mercury and lead poisoning. Group: Pharmaceutical. Alternative Names: trisodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxymethyl)amino]acetate; Edetate trisodium; edta trisodium; Trisodium edetate; Trisodium ethylenediaminetetraacetate; Ethylenediaminetetraacetic acid trisodium salt; 150-38-9; EDTA trisodium salt; UNII-420IP9. CAS No. 150-38-9. Pack Sizes: 1mg;1g;10g. Product ID: 150-38-9. Molecular formula: C10H13N2Na3O8. Mole weight: 358.19. Custom synthesis is available. Send your inquiries for more information. | London |
| Sodium Acetate | Leading UK bulk distributor of Sodium Acetate CAS No. 127-09-3. Visit our website for more information and to request a quote. Uses: Manufacturing and Industrial. Group: Commodity Chemicals. Pack Sizes: Pallet 25Kg Bags. |  United Kingdom |
| Acetic Acid | Monarch Chemicals are a leading UK distributor of bulk acetic acid, offering the solution in various batch sizes from small packs to bulk road tankers. Uses: Acidity regulator and preservative Food additive E260. Also used in descaling agents, as a chemical reagent and offers various industrial applications. Group: Acids. Alternative Names: Methanecarboxylic Acid, Ethanoic Acid. Pack Sizes: Poly, Drum, IBC and Bulk Tanker. | United Kingdom |
| GSK525762 | GSK525762A, also known as I-BET-762 and GSK525762, is a small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins with potential antineoplastic activity. Upon administration, the BET inhibitor GSK525762 binds to the acetylated lysine recognition motifs on the bromodomain of BET proteins, thereby preventing the interaction between the BET proteins and acetylated histone peptides. This disrupts chromatin remodeling and gene expression. Prevention of the expression of certain growth-promoting genes may lead to an inhibition of tumor cell growth. Characterized by a tandem repeat of bromodomain at the N-terminus, BET proteins, comprising of BRD2, BRD3, BRD4 and BRDT, are transcriptional regulators that play an important role during development and cellular growth. Group: Pharmaceutical. Alternative Names: GSK525762; GSK525762; GSK525762; GSK525762A; GSK-525762A; GSK 525762A; I-BET-762; I-BET762; I-BET 762; molibresib. CAS No. 1260907-17-2. Pack Sizes: 25 mg. Product ID: B2693-457801. Molecular formula: C22H22ClN5O2. Mole weight: 423.9. Custom synthesis is available. Send your inquiries for more information. | London |
| Oleandrin | Oleandrin, also known as PBI-05204, is a lipid soluble cardiac glycoside with potential antineoplastic activity. Upon administration, oleandrin specifically binds to and inhibits the alpha3 subunit of the Na/K-ATPase pump in human cancer cells. This may inhibit the phosphorylation of Akt, upregulate MAPK, inhibit NF-kb activation and inhibit FGF-2 export and may downregulate mTOR thereby inhibiting p70S6K and S6 protein expression. All of this may lead to an induction of apoptosis. As cancer cells with relatively higher expression of the alpha3 subunit and with limited expression of the alpha1 subunit more sensitive to oleandrin, one may predict the tumor response to treatment with lipid-soluble cardiac glycosides such as oleandrin based on the tumors Na/K-ATPase pump protein subunit expression. Overexpression of the alpha3 subunit in tumor cells correlates with tumor proliferation. Uses: Anti-proliferative. Group: Pharmaceutical. Alternative Names: (3b,5b,16b)-16-(Acetyloxy)-3-[(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide; Neriolin; Corrigen. CAS No. 465-16-7. Pack Sizes: 10 mg. Product ID: NP6109. Molecular formula: C32H48O9. Mole weight: 576.72. Custom synthesis is available. Send your inquiries for more information. | London |
| Palbociclib | Palbociclib is an orally available cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. Palbociclib selectively inhibits cyclin-dependent kinase 4 (CDK4) and 6 (CDK6), thereby inhibiting retinoblastoma (Rb) protein phosphorylation early in the G1 phase leading to cell cycle arrest. Group: Pharmaceutical. Alternative Names: PD 0332991; PD0332991; PD-0332991; Ibrance; 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperazin-1-yl)pyridin-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one; 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one. CAS No. 571190-30-2. Pack Sizes: 5 g. Product ID: BBF-05853. Molecular formula: C24H29N7O2. Mole weight: 447.53. Custom synthesis is available. Send your inquiries for more information. | London |
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