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| Product | Description | |
|---|---|---|
| 1,6-Anhydro-beta-D-glucopyranose (Levoglucosan) | 1g Pack Size. Group: Biochemicals, Carbohydrates. Formula: C6H10O5. CAS No. 498-07-7. Prepack ID : 13585366-1g. Molecular Weight : 162.14. |  |
| 4-Chloro-2-propylsulfanyl-pyrimidine | An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Group: Pharmaceutical. CAS No. 1351990-36-7. Pack Sizes: 100 mg. Product ID: B0027-284938. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Coluracetam | MKC-231 (10(-10)-10(-6) moll) significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholine mustard aziridinium ion (AF64A) treated rats, but not of normal rats. MKC-231 did not affect the AChE activity, [3H]- quinuclidinyl benzilate binding, and [3H]-pirenzepine binding. Oral administration of MKC-231 (1-10 mg/kg) significantly improved the learning deficits in the Morris' water maze of AF64A-treated rats, but it did not produce any significant side effects, like tremor, salivation or hypothermia, which were observed in rats treated with high doses of tacrine [1]. In acute behavioral experiments, MKC-231 and THA had no significant effect on AF64A-induced memory deficits at any doses tested (0.3, 1.0 and 3.0 mg/kg), whereas Dup 996, at a dose of 1.0 mg/kg, significantly improved memory deficits. In chronic experiments, MKC-231 improved memory deficit at all doses tested (0.3, 1.0, or 3.0 mg/kg p.o., once daily for 11 days) and Dup 996 did so only at a dose of 3.0 mg/kg, whereas THA did not improve memory deficit at any doses tested. Group: Pharmaceutical. CAS No. 135463-81-9. Pack Sizes: 2 g. Product ID: B0084-083492. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ONO-4059 | ONO-4059, a BTK inhibitor, has been found to have potential effect against sorts of malignancies by influencing the B-cell development. It is currently under Phase II trail to study its effect against Chronic lymphocytic leukaemia. IC50: 2.2 nM. Group: Pharmaceutical. CAS No. 1351636-18-4. Pack Sizes: 100 mg. Product ID: B2693-474503. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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