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| Product | Description | |
|---|---|---|
| LDN-212854 | LDN-212854 is a potent and selective BMP receptor inhibitor with IC50 of 1.3 nM for ALK2. LDN-212854 exhibits some selectivity for ALK2 in preference to other BMP type I receptors, ALK1 and ALK3, which may permit the interrogation of ALK2-mediated signaling, transcriptional activity, and function. LDN-212854 potently inhibits heterotopic ossification in an inducible transgenic mutant ALK2 mouse model of fibrodysplasia ossificans progressiva. Group: Pharmaceutical. Alternative Names: BMP Inhibitor III; LDN 212854; 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline. CAS No. 1432597-26-6. Pack Sizes: 100 mg. Product ID: B2693-286416. Molecular formula: C25H22N6. Mole weight: 406.48. Custom synthesis is available. Send your inquiries for more information. |  London |
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