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| Product | Description | |
|---|---|---|
| A 419259 | A-419259 is a potent inhibitor of Src family kinases. IC50 values for src, lck, blk, csk, fyn and lyn range between 15 and 50 nM. Group: Pharmaceutical. Alternative Names: A419259; A-419259; RK 20449; RK20449; RK-20449. CAS No. 364042-47-7. Pack Sizes: 1mg;1g;10g. Product ID: 364042-47-7. Molecular formula: C29H34N6O. Mole weight: 482.62. Custom synthesis is available. Send your inquiries for more information. |  London |
| JNJ-26483327 | JNJ-26483327 is an orally bioavailable, small-molecule, multitargeted reversible tyrosine kinase inhibitor with potential antineoplastic activity. Multitargeted tyrosine kinase inhibitor JNJ-26483327 binds to and inhibits several members of the epidermal growth factor receptor (EGFR) family, including EGFR, HER2 and HER4; Src family kinases (Lyn, Yes, Fyn, Lck and Src); and vascular endothelial growth factor receptor type 3 (VEGFR3). By inhibiting several different signaling molecules that play crucial roles at various stages in tumorigenesis, this agent may inhibit tumor growth, invasion, migration and metastasis. In addition, JNJ-26483327 crosses the blood-brain barrier (BBB). Group: Pharmaceutical. Alternative Names: JNJ-26483327; JNJ 26483327; JNJ26483327. CAS No. 807640-87-5. Pack Sizes: 10 mg. Product ID: B0084-462547. Molecular formula: C22H25BrN4O2. Mole weight: 457.372. Custom synthesis is available. Send your inquiries for more information. | London |
| LCKLSL acetate | LCKLSL acetate is a N-terminal hexapeptide and a competitive annexin A2 (AnxA2) inhibitor. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B1370-447444. Molecular formula: C32H61N7O10S. Mole weight: 735.93. Custom synthesis is available. Send your inquiries for more information. | London |
| LDC1267 | LDC1267 is a highly selective TAM kinase inhibitor with IC50 of <5 nM, 8 nM, and 29 nM for Mer, Tyro3, and Axl, respectively. Displays lower activity against Met, Aurora B, Lck, Src, and CDK8. Group: Pharmaceutical. Alternative Names: LDC1267; LDC 1267; LDC-1267. CAS No. 1361030-48-9. Pack Sizes: 50 mg. Product ID: B0084-463399. Molecular formula: C30H26F2N4O5. Mole weight: 560.55. Custom synthesis is available. Send your inquiries for more information. | London |
| STAT5-IN-1 | STAT5-IN-1, a cell-permeable nonpeptidic nicotinoyl hydrazone compound, is a selective STAT5 inhibitor with an IC50 of 47 μM for STAT5β isoform with much less effect towards the SH2 domain of STAT1, STAT3, or Lck (IC50>500 μM). Group: Pharmaceutical. Alternative Names: MDK-6314; STAT5 Inhibitor; STAT5Inhibitor; STAT5-Inhibitor; MDK 6314; MDK6314. N-[(E)-(4-oxochromen-3-yl)methylideneamino]pyridine-3-carboxamide; STAT5 Inhibitor. CAS No. 285986-31-4. Pack Sizes: 50 mg. Product ID: B0084-007364. Molecular formula: C16H11N3O3. Mole weight: 293.28. Custom synthesis is available. Send your inquiries for more information. | London |
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