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| Product | Description | |
|---|---|---|
| AAI101 | AAI101 is a novel β-lactamase inhibitor with activity against extended-spectrum β-lactamases (ESBL), as well as, some class A and class D carbapenemases. Uses: Beta-lactamase inhibitors. Group: Pharmaceutical. CAS No. 1001404-83-6. Pack Sizes: 50 mg. Product ID: B2693-007726. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Amoxicillin trihydrate | Amoxicillin is a moderate-spectrum, bacteriolytic, β-lactam antibiotic in the aminopenicillin family used to treat bacterial infections caused by susceptible Gram-positive and Gram-negative microorganisms. It is usually the drug of choice within the class because it is better-absorbed, following oral administration, than other β-lactam antibiotics. It is also susceptible to degradation by β-lactamase-producing bacteria, which are resistant to a narrow spectrum of β-lactam antibiotics, such as penicillin. Group: Pharmaceutical. CAS No. 61336-70-7. Pack Sizes: 100 g. Product ID: NP2685. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avibactam Impurities | Avibactam impurities, indispensable for evaluating the purity and safety of Avibactam, a non-β-lactam β-lactamase inhibitor, are paramount when combined with antibiotics such as ceftazidime, targeting formidable infections by resistant bacteria. Thorough comprehension of these impurities enhances formulation effectiveness and mitigates adverse effects during therapeutic applications. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avibactam Impurity 6 | An impurity of Avibactam, a non-β lactam β-lactamase inhibitor that inactivates some β-lactamases. Group: Pharmaceutical. CAS No. 1192651-49-2. Pack Sizes: 25 mg. Product ID: B2694-467077. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avibactam Sodium Salt | Avibactam Sodium Salt, a novel non-?-lactam ?-lactamase inhibitor, binds covalently to Ambler class A ?-lactamases, including KPCs, Ambler class C and some class D b-lactamases. In combination with ceftazidime, Avibactam is a new drug application for avibactam , and was approved by the FDA on February 25, 2015, to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. Avibactam has limited intrinsic antimicrobial activity but restores the in vitro activity of b-lactams including ceftazidime, ceftaroline, the active metabolite of ceftaroline fosamil, and aztreonam against ESBL-producing pathogens. Group: Pharmaceutical. CAS No. 1192491-61-4. Pack Sizes: 500 mg. Product ID: B0084-465274. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cefepime hydrochloride hydrate | Cefepime is an extended-spectrum parenteral cephalosporin antibiotic active in vitro against a broad spectrum of gram-positive and gram-negative aerobic bacteria. Cefepime dosing was 1-4 g/day (0.5-2.0 g twice daily) for adults; ceftazidime dosing was 1-6 g/day (0.5 g every 12 hours to 2.0 g every 8 hours). A limited number of cefepime-treated patients received 2 g every 8 hours. The median length of dosing for both cefepime and ceftazidime was 7 days. Cefepime has a decreased propensity to induce beta-lactamases compared with other beta-lactam antibiotics. Cefepime has a pharmacokinetic disposition similar to that of other renally eliminated cephalosporins, with a half-life of approximately 2 hours. Cefepime has demonstrated clinical efficacy against a variety of infections, including urinary tract infections, pneumonia, and skin structure infections. Cefepime is generally well tolerated. Group: Pharmaceutical. CAS No. 123171-59-5. Pack Sizes: 5 g. Product ID: BBF-03810. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Clavulanate Potassium (1:1 mixture with silicon dioxide) | Clavulanate Potassium is a semi-synthetic beta-lactamase inhibitor isolated from streptomyces. It contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site. It is used in conjunction with beta-lactamase susceptible penicillins to treat infections caused by beta-lactamase producing organisms. It is commonly combined with amoxicillin or ticarcillin to increase its effectiveness. Uses: Beta-lactamase inhibitors. Group: Pharmaceutical. CAS No. 61177-45-5. Pack Sizes: 10 g. Product ID: BBF-03915. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ertapenem Sodium | Ertapenem Sodium is the sodium salt of ertapenem. Ertapenem has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of ertapenem results from the inhibition of cell wall synthesis and is mediated through ertapenem binding to penicillin binding proteins (PBPs). In Escherichia coli, it has strong affinity toward PBPs 1a, 1b, 2, 3, 4 and 5 with preference for PBPs 2 and 3. Ertapenem is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases. Ertapenem is hydrolyzed by metallo-beta-lactamases. Ertapenem has been shown to be active against most isolates of the following microorganisms in vitro and in clinical infections. Group: Pharmaceutical. CAS No. 153773-82-1. Pack Sizes: 1 g. Product ID: BBF-03993. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Nacubactam | Nacubactam is a beta-lactamase inhibitor used for treating bacterial infections. Nacubactam acts as a penicillin binding protein (PBP) 2-active antibacterial, and gives β-lactamase-independent potentiation of β-lactams targeting other PBPs. Group: Pharmaceutical. CAS No. 1452458-86-4. Pack Sizes: 25 mg. Product ID: B1370-381241. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Nitrocefin | Nitrocefin is a chromogenic cephalosporin substrate routinely used to detect the presence of beta-lactamase enzymes produced by various microbes. Group: Pharmaceutical. CAS No. 41906-86-9. Pack Sizes: 100 mg. Product ID: BBF-03759. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Penicillanic Acid Sodium Salt | An impurity of Sulbactam. Sulbactam is an irreversible inhibitor of β-lactamase; it binds to the enzyme and does not allow it to degrade the antibiotic. Group: Pharmaceutical. CAS No. 4027-62-7. Pack Sizes: 250 mg. Product ID: B2694-373162. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Relebactam | Relebactam, a diazabicyclooctane derivative, has a broad spectrum inhibitory activity against β-lactamases. It has been studied to be probably effective in the treatment of Gram-negative bacterial infections combinated with Primaxin. Uses: Beta-lactamase inhibitors. Group: Pharmaceutical. CAS No. 1174018-99-5. Pack Sizes: 100 mg. Product ID: B2693-474368. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sulbactam Impurities | Sulbactam Impurities, as critical analytical benchmarks, are integral to the biomedical sector for validating sulbactam formulation integrity. These impurities facilitate the detection of degradation byproducts in sulbactam, a beta-lactamase antagonist essential for combating bacterial infections and amplifying the efficacy of beta-lactam antibiotic therapies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sulbactam Sodium | Sulbactam is an irreversible inhibitor of β-lactamase. It binds to the enzyme and does not allow it to degrade the antibiotic. Group: Pharmaceutical. CAS No. 69388-84-7. Pack Sizes: 5 g. Product ID: BBF-04624. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sultamicillin tosylate | Sultamicillin is a compound composed of sulbactam and ampicillin linked as a double ester. Sulbactam is a semisynthetic beta-lactamase inhibitor, which exhibits improved antibacterial activity in combination with ampicillin. Group: Pharmaceutical. CAS No. 83105-70-8. Pack Sizes: 500 mg. Product ID: B0001-078090. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tazobactam Impurities | Tazobactam Impurities, integral to the pharmaceutical sector, ensure the purity and potency of tazobactam, an essential beta-lactamase inhibitor used with piperacillin to battle resistant bacteria. Their significance lies in stringent quality control and regulatory adherence, vital during the complex processes of drug development and manufacturing. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Temocillin disodium salt | Temocillin disodium salt is the salt of Temocillin. Temocillin is a β-lactamase-resistant penicillin that is effective against Gram-negative bacteria. Uses: Anti-bacterial agents. Group: Pharmaceutical. CAS No. 61545-06-0. Pack Sizes: 10 mg. Product ID: B0001-145294. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Zidebactam | Zidebactam is a β-lactamase inhibitor which possesses intrinsic antibacterial activity. Zidebactam is undergoing clinical development for the treatment of carbapenem-resistant Gram-negative infections. Uses: Bacterial infections. Group: Pharmaceutical. CAS No. 1436861-97-0. Pack Sizes: 10 mg. Product ID: B2693-475437. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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