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| Product | Description | |
|---|---|---|
| L-685,458 | L-685,458 is a potent and selective inhibitor of γ-secretase (IC50 = 17 nM) that shows 50-fold selectivity over a variety of aspartyl proteases. It also inhibits Aβ40 and Aβ42 peptides (in human neuroblastoma cells: IC50 = 48 and 67 nM respectively). Uses: Gamma secretase inhibitors and modulators. Group: Pharmaceutical. Alternative Names: L-685458; tert-butyl N-[(2S,3R,5R)-6-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-benzyl-3-hydroxy-6-oxo-1-phenylhexan-2-yl]carbamate. CAS No. 292632-98-5. Pack Sizes: 25 mg. Product ID: B2693-286396. Molecular formula: C39H52N4O6. Mole weight: 672.85. Custom synthesis is available. Send your inquiries for more information. |  London |
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