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| Product | Description | |
|---|---|---|
| Kynurenine Impurities | Kynurenine Impurities represent vital components in the intricate examination of the kynurenine pathway's modulation, intricately connected to neurodegenerative afflictions like Alzheimer's and Parkinson's. These impurities unravel complex pathophysiological mechanisms and aid in devising therapeutic strategies targeting disruptions in tryptophan metabolism, thereby enhancing the understanding of related disorders. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| L-Kynurenine-[13C4,15N] | L-Kynurenine-[13C4,15N] is a labelled L-kynurenine. L-Kynurenine Sulfate is a tryptophan metabolite which is a precursor of kynurenic acid and an antagonist of N-methyl-aspartate receptor. Group: Pharmaceutical. Pack Sizes: 1 mg. Product ID: BLP-014128. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Formyl-L-kynurenine | N-Formylkynurenine is a L-kynurenine derivative. Group: Pharmaceutical. CAS No. 3978-11-8. Pack Sizes: 5 mg. Product ID: B2694-334047. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| NLG-919 | NLG919 is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), a cytosolic enzyme responsible for the oxidation of the essential amino acid tryptophan into kynurenine. By inhibiting IDO1 and decreasing kynurenine in tumor cells, this agent increases tryptophan levels, restores the proliferation and activation of various immune cells, including dendritic cells (DCs), natural killer (NK) cells, T-lymphocytes, and causes a reduction in tumor-associated regulatory T-cells (Tregs). Group: Pharmaceutical. CAS No. 1402836-58-1. Pack Sizes: 50 mg. Product ID: B0084-462741. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ro 61-8048 | Potent and competitive kynurenine 3-hydroxylase inhibitor (IC50 = 37 nM). Shows antidystonic, anticonvulsant and neuroprotective effects in vivo. Blood-brain barrier permeable. Orally active. Group: Pharmaceutical. CAS No. 199666-03-0. Pack Sizes: 50 mg. Product ID: B0084-272333. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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