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| Product | Description | |
|---|---|---|
| 3-Hydroxy-DL-kynurenine-[5,8,8-d3] | 3-Hydroxy-DL-kynurenine-[5,8,8-d3] is a labelled 3-hydroxy-DL-kynurenine. 3-hydroxy-DL-kynurenine is a byproduct of metabolism of tryptophan. Group: Pharmaceutical. Alternative Names: 2-amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid-d3; 3-Hydroxykynurenine-5,5,8-d3. Pack Sizes: 10 mg. Product ID: BLP-009163. Molecular formula: C10H9D3N2O4. Mole weight: 227.24. Custom synthesis is available. Send your inquiries for more information. |  London |
| L-Kynurenine-[13C4,15N] | L-Kynurenine-[13C4,15N] is a labelled L-kynurenine. L-Kynurenine Sulfate is a tryptophan metabolite which is a precursor of kynurenic acid and an antagonist of N-methyl-aspartate receptor. Group: Pharmaceutical. Alternative Names: L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid-13C4,15N; L-Kynurenine-13C4,15N. Pack Sizes: 1 mg. Product ID: BLP-014128. Molecular formula: C6[13C]4H12N[15N]O3. Mole weight: 213.17. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Formyl Kynurenine | N-Formyl Kynurenine is an important intermediate in the kynurenine pathway, which is a major metabolic pathway for the metabolism of tryptophan in mammals. Group: Pharmaceutical. Alternative Names: 2-amino-4-(2-formamidophenyl)-4-oxo-butanoic acid; α-Amino-2-(formylamino)-γ-oxo-Benzenebutanoic Acid; 3-(N-Formylanthraniloyl)alanine; Formylkynurenine; N-Formylkynurenine. CAS No. 1022-31-7. Pack Sizes: 10 mg. Product ID: B1370-187911. Molecular formula: C11H12N2O4. Mole weight: 236.23. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Formyl-L-kynurenine | N-Formylkynurenine is a L-kynurenine derivative. Group: Pharmaceutical. Alternative Names: (S)-2-Amino-4-(2-formamidophenyl)-4-oxobutanoic acid. CAS No. 3978-11-8. Pack Sizes: 5 mg. Product ID: B2694-334047. Molecular formula: C11H12N2O4. Mole weight: 236.22. Custom synthesis is available. Send your inquiries for more information. | London |
| NLG-919 | NLG919 is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), a cytosolic enzyme responsible for the oxidation of the essential amino acid tryptophan into kynurenine. By inhibiting IDO1 and decreasing kynurenine in tumor cells, this agent increases tryptophan levels, restores the proliferation and activation of various immune cells, including dendritic cells (DCs), natural killer (NK) cells, T-lymphocytes, and causes a reduction in tumor-associated regulatory T-cells (Tregs). Group: Pharmaceutical. Alternative Names: GDC0919; GDC-0919; GDC 0919; NLG919; NLG 919; NLG-919; RG6078; RG-6078; RG 6078. CAS No. 1402836-58-1. Pack Sizes: 50 mg. Product ID: B0084-462741. Molecular formula: C18H22N2O. Mole weight: 282.38. Custom synthesis is available. Send your inquiries for more information. | London |
| Ro 61-8048 | Potent and competitive kynurenine 3-hydroxylase inhibitor (IC50 = 37 nM). Shows antidystonic, anticonvulsant and neuroprotective effects in vivo. Blood-brain barrier permeable. Orally active. Group: Pharmaceutical. Alternative Names: Ro61-8048; Ro 61-8048; Ro-61-8048; Ro618048; Ro 618048; Ro-618048. CAS No. 199666-03-0. Pack Sizes: 50 mg. Product ID: B0084-272333. Molecular formula: C17H15N3O6S2. Mole weight: 421.45. Custom synthesis is available. Send your inquiries for more information. | London |
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