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JK-184 JK-184 is a potent downstream hedgehog (Hh) signaling antagonist that functions by alcohol dehydrogenase 7 (Adh7) inhibition, preventing Gli-dependent transcriptional activity (IC50 = 30 nM). Hedgehog signaling plays a key role in a wide variety of developmental processes as well as cancer progression. JK-184 exhibits antiproliferative activity. Uses: Differentiation. Group: Pharmaceutical. Alternative Names: JK184; JK 184. CAS No. 315703-52-7. Pack Sizes: 100 mg. Product ID: B2693-462944. Molecular formula: C19H18N4OS. Mole weight: 350.44. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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