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| Product | Description | |
|---|---|---|
| Chloromethyl (Isopropoxy) Dimethylsilane | Chloromethyl (Isopropoxy) Dimethylsilane Uses: Pharmaceutical R&D. Group: Intermediates. CAS No. 18171-11-4. Pack Sizes: Enquire for MOQ. Categories: Nordmann UK Fine Chemicals (Formerly Melrob-Eurolabs). |  UK / EU / USA / Japan |
| Abiraterone isopropyl ether | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: 3-[3-(1-Methylethoxy)androsta-5,16-dien-17-yl]pyridine; 3-((3S,8R,9S,10R,13S,14S)-3-Isopropoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. CAS No. 2484719-15-3. Pack Sizes: 1mg;1g;10g. Product ID: 2484719-15-3. Molecular formula: C27H37NO. Mole weight: 391.59. Custom synthesis is available. Send your inquiries for more information. |  London |
| Ceritinib | An anaplastic lymphoma kinase (ALK)-positive inhibitor used for the treatment of non-small cell lung cancer (NSCLC). It less potently inhibits IGF-1R, InsR, and STK22D and IC50 value is 8, 7, and 23 nM. LDK378 is also minimally effective against a panel of other kinases. In Sep 2016, Interim adverse events and efficacy data from phase III ASCEND-4 trial in non small cell lung cancer released by Novartis. In Oct 2016, efficacy data from the phase III ASCEND-3 and ASCEND-5 trial in non small cell lung cancer was presented. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine, LDK-378, LDK378; LDK 378; Zykadia; NVP-LDK378-NX. CAS No. 1032900-25-6. Pack Sizes: 250 mg. Product ID: B0084-462148. Molecular formula: C28H36ClN5O3S. Mole weight: 558.14. Custom synthesis is available. Send your inquiries for more information. | London |
| Nutlin-3 | Nutlin-3 is an MDM2 antagonist, inhibiting p53-Mdm2 interaction (IC50=0.09 μM) via affecting p53 binding pocket of MDM2. It has been studied in anticancer reseaches. Group: Pharmaceutical. Alternative Names: (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one; 4-[4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one. CAS No. 548472-68-0. Pack Sizes: 100 mg. Product ID: B0084-094267. Molecular formula: C30H30Cl2N4O4. Mole weight: 581.49. Custom synthesis is available. Send your inquiries for more information. | London |
| Nutlin-3b | Nutlin-3b, the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM. Group: Pharmaceutical. Alternative Names: Nutlin-3; nutlin 3; Nutlin 3b; FJA1772CVW; (+)-Nutlin-3; CHEMBL2152332; CHEBI:46742; 4-[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one; 2-Piperazinone, 4-(((4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-(4-methoxy-2-(1-methylethoxy)phenyl)-1H-imidazol-1-yl)carbonyl)-; 4-((4R,5S)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one; 4-[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl]piperazin-2-one; 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone; cis-4-{[4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydroimidazol-1-yl]carbonyl}piperazin-2-one. CAS No. 675576-97-3. Pack Sizes: 100 mg. Product ID: B2693-459422. Molecular formula: C30H30Cl2N4O4. Mole weight: 581.49. Custom synthesis is available. Send your inquiries for more information. | London |
| tert-Butyl isopropyl ether | Tert-Butyl isopropyl ether is a solvent or an intermediate in the synthesis of complex organic molecules. Group: Pharmaceutical. Alternative Names: tert-Butyl isopropyl ether; 2-Isopropoxy-2-methylpropane. CAS No. 17348-59-3. Pack Sizes: 1 g. Product ID: B1370-085774. Molecular formula: C7H16O. Mole weight: 116.2. Custom synthesis is available. Send your inquiries for more information. | London |
| TL13-112 | TL13-112 is a potent and selective PROTAC® degrader targeting anaplastic lymphoma kinase (ALK) with an IC50 value of 0.14 nM, consisiting of a cereblon E3 ligase ligand Pomalidomide conjugated to an ALK inhibitor by a linker. Group: Pharmaceutical. Alternative Names: TL 13-112; TL-13-112; N-[2-[2-[2-[4-[4-[[5-Chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-1-piperidinyl]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]acetamide; N-(2-{2-[2-(4-{4-[(5-Chloro-4-{[2-(isopropylsulfonyl)phenyl]amino}-2-pyrimidinyl)amino]-5-isopropoxy-2-methylphenyl}-1-piperidinyl)ethoxy]ethoxy}ethyl)-N2-[2-(2,6-dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]glycinamide; Acetamide, N-[2-[2-[2-[4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-1-piperidinyl]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-. CAS No. 2229037-19-6. Pack Sizes: 5 mg. Product ID: B1370-292444. Molecular formula: C49H60ClN9O10S. Mole weight: 1002.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Titanium ethoxide | Titanium ethoxide, contains 10-15% Titanium(IV) isopropoxide. Group: Metal alkoxides. CAS No. 3087-36-3. Pack Sizes: 1kg; 5kg; 25kg; 100kg; 200kgs. Product ID: AB106340. Categories: Coatings and as catalysts; 3; titanium(iv) ethoxide. |  |
| Titanium isopropoxide | Titanium isopropoxide; 97%. Group: Metal alkoxides. CAS No. 546-68-9. Pack Sizes: 1kg; 5kg; 25kg; 100kg; 200kgs. Product ID: AB106344. Categories: Coatings and as catalysts; titanium tetraisopropanolate. | |
| Titanium(IV) isopropoxide | 100g Pack Size. Group: Building Blocks, Catalysts, Research Organics & Inorganics. Formula: C12H28O4T. CAS No. 546-68-9. Prepack ID : 33520313-100g. Molecular Weight : 284.22. |  |
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