Irinotecan Suppliers UK

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Product
Irinotecan-[d10] Hydrochloride Irinotecan-[d10] Hydrochloride is the labelled analogue of Irinotecan, which is a DNA topoisomerase inhibitor. Group: Pharmaceutical. CAS No. 718612-62-5. Pack Sizes: 10 mg. Product ID: BLP-012397. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Irinotecan EP Impurity A An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Group: Pharmaceutical. CAS No. 103816-16-6. Pack Sizes: 5 mg. Product ID: B1370-473338. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Irinotecan EP Impurity B 10-Hydroxycamptothecin inhibits the growth of BT-20 and MDA-231 cell with IC50 of 34.3 nM and 7.27 nM, respectively, more potently than camptothecin (CPT) with IC50 of >500 nM. 10-Hydroxycamptothecin is also an impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Uses: Anti-cancer. Group: Pharmaceutical. CAS No. 19685-09-7. Pack Sizes: 5 g. Product ID: B2703-086753. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Irinotecan EP Impurity E (SN-38) An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. It inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. Uses: The treatment of colorectal cancer. Group: Pharmaceutical. CAS No. 86639-52-3. Pack Sizes: 1 g. Product ID: BADC-01393. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Irinotecan EP Impurity G An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Group: Pharmaceutical. CAS No. 947687-01-6. Pack Sizes: 2.5 mg. Product ID: B2694-468001. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Irinotecan Hydrochloride Trihydrate The hydrochloride salt of Irinotecan. Irinotecan is a prodrug that can be activated to 7-ethyl-10-hydroxy-camptothecin (SN-38) by the carboxylesterase-converting enzyme. SN-38 inhibits topoisomerase I to suppress DNA replication and promote cell death. Group: Pharmaceutical. CAS No. 136572-09-3. Pack Sizes: 1 g. Product ID: B0084-057943. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Irinotecan Impurities Irinotecan Impurities function as essential elements within the pharmaceutical landscape, primarily tasked with evaluating the purity and stability of Irinotecan, a crucial anticancer agent for colorectal and additional malignancies. These impurities enable thorough quality assurance, safeguarding therapeutic effectiveness and safety by pinpointing and measuring prospective degradative byproducts. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
(S)-4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione (S)-4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione is a key intermediate for the synthesis of irinotecan and camptothecin analogues. It is also an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Pharmaceutical. CAS No. 110351-94-5. Pack Sizes: 10 g. Product ID: BBF-05888. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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