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| Product | Description | |
|---|---|---|
| Acetanilide-[d6] | Acetanilide-[d6] is the labelled analogue of Acetanilide, which is an impurity of Acetaminophen. Uses: N-d readily exchanges in protic solvents. Group: Pharmaceutical. CAS No. 141801-46-9. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-010667. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Benzamil | Benzamil is a Na+/Ca2+ exchanger (NCX) inhibitor and epithelial sodium channel (ENaC) blocker. Benzamil has been developed as a promising treatment for cystic fibrosis. Group: Pharmaceutical. CAS No. 2898-76-2. Pack Sizes: 50 mg. Product ID: B2693-070965. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BI-3406 | BI-3406 is a potent and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1). SOS1 is the guanine nucleotide exchange factor (GEF) and activator of RAS, and mutants of RAS are major oncogenes and occur in many human cancers. Inhibition of SOS1 in a mutant KRAS cell line can suppress tumor growth. Group: Pharmaceutical. CAS No. 2230836-55-0. Pack Sizes: 5 mg. Product ID: B2693-363125. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Calcium polystyrene sulfonate | Calcium polystyrene sulfonate is an ion exchange resin used primarily in hyperkalemia caused by acute and chronic renal dysfunction. Group: Pharmaceutical. CAS No. 37286-92-3. Pack Sizes: 5 g. Product ID: B2699-019837. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CHAPS | CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins. It is often used as a detergent in the solubilization and purification of membrane proteins for several advantageous reasons. It is also useful in ion exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. Uses: Used as a non-denaturing biological detergent; chaps is a zwitterionic detergent used in the laboratory to solubilize biological macromolecules such as proteins. it is used as a non-denaturing solvent in the process of protein purification and is especially useful in purifying membrane proteins, which are often sparingly soluble or insoluble in aqueous solution due to their native hydrophobicity. Group: Pharmaceutical. CAS No. 75621-03-3. Pack Sizes: 50 g. Product ID: B1370-300063. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Demineralised Water | Demineralised water is a very pure type of water that doesn't contain mineral salts or impurities such as chloride or sodium. It's made by passing non-pure water through an ion exchange resin bed. Also known as demin water, demineralised water has a wide range of applications. Thanks to its high purity, the substance is often used as an ingredient in pharmaceutical products and as a testing medium in laboratories. Uses: Battery water, laboratory solvent. Group: General Chemicals. Alternative Names: Demineralized Water, Demin Water. CAS No. 7732-18-5. Pack Sizes: 5L, 25L, 1000L, 25000 Litres Bulk. | Chemicals.co.uk |
| EIPA | EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Uses: Epithelial sodium channel blockers. Group: Pharmaceutical. CAS No. 1154-25-2. Pack Sizes: 50 mg. Product ID: B2693-047130. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| EIPA hydrochloride | EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Group: Pharmaceutical. CAS No. 1345839-28-2. Pack Sizes: 250 mg. Product ID: B2693-334168. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| KB-R7943 mesylate | KB-R7943 is a potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 μM). Group: Pharmaceutical. CAS No. 182004-65-5. Pack Sizes: 100 mg. Product ID: B1370-207121. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| NITRIC ACID 67% | A inorganic compound with the formula HNO3. It is a highly corrosive mineral acid. The compound is colourless, but older samples tend to be yellow cast due to decomposition into oxides of nitrogen. Most commercially available nitric acid has a concentration of 68% in water. When the solution contains more than 86% HNO3, it is referred to as fuming nitric acid. Depending on the amount of nitrogen dioxide present, fuming nitric acid is further characterized as red fuming nitric acid at concentrations above 86%, or white fuming nitric acid at concentrations above 95%. Uses: Intermediate for chemical syntheses.Intermediate in manufacture of inorganic and organicchemicals incl. fertilizers.Formulation of mixtures (fertilizer, metal surfacetreatment product, cleaning product, detergent andmaintenance product).Processing aid in industry, including laboratoryapplications, such as pH regulator, neutralisationagent, oxidising agent.Reactive agent in inorganic and organic synthesis.Regeneration of ion exchange resins.pH control.Laboratory agent.Surface treatment product. In cleaning products. CAS No. 7697-37-2. |  |
| NITRIC ACID 99% (CONCENTRATED) | A inorganic compound with the formula HNO3. It is a highly corrosive mineral acid. The compound is colourless, but older samples tend to be yellow cast due to decomposition into oxides of nitrogen. Most commercially available nitric acid has a concentration of 68% in water. When the solution contains more than 86% HNO3, it is referred to as fuming nitric acid. Depending on the amount of nitrogen dioxide present, fuming nitric acid is further characterized as red fuming nitric acid at concentrations above 86%, or white fuming nitric acid at concentrations above 95%. Uses: Intermediate for chemical syntheses.Intermediate in manufacture of inorganic and organic chemicals incl. fertilizers.Formulation of mixtures (fertilizer, metal surface treatment product, cleaning product, detergentand maintenance product).Processing aid in industry, including laboratory applications, such as pH regulator, neutralisationagent, oxidising agent.Reactive agent in inorganic and organic synthesis.Regeneration of ion exchange resins.pH control.Laboratory agent.Surface treatment product.In cleaning products. CAS No. 007-004-00-1. | |
| Tenapanor | This active molecular is an sodium-proton exchanger NHE3 inhibitor under the development of Ardelyx. This antiporter protein plays a really important role in sodium handling in the gastrointestinal tract and kidney and it regulates the levels of sodium absorbed and secreted by the body. Therefore, tenapanor can be useful in the treatment of chronic kidney disease and hypertension because both of them are exacerbated by excess sodium in the diet. In Oct 2016, Phase-III clinical trials in Hyperphosphataemia (in patients with end-stage renal disease) in USA was on going. Uses: Hyperphosphataemia. Group: Pharmaceutical. CAS No. 1234423-95-0. Pack Sizes: 25 mg. Product ID: B0084-475197. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tenapanor HCl | Tenapanor, also known as AZD-1722 and RDX 5791, is a first-in-class, small-molecule inhibitor of the gastrointestinal sodium/hydrogen exchanger NHE3. Tenapanor possesses an excellent preclinical safety profile and, as of now, there are no serious concerns about its side effects. Tenapanor acts in the gastrointestinal tract to reduce the absorption of sodium and phosphate, with minimal systemic drug exposure. Group: Pharmaceutical. CAS No. 1234365-97-9. Pack Sizes: 50 mg. Product ID: B2693-007851. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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