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| Product | Description | |
|---|---|---|
| Insulin aspart | Insulin aspart is an insulin analog that functions faster and lasts for a shorter time than regular insulin. Insulin aspart has been indicated for the treatment of type 1 and type 2 diabetes. Group: Pharmaceutical. Alternative Names: DL-phenylalanyl-DL-valyl-DL-asparagyl-DL-glutaminyl-DL-histidyl-DL-leucyl-DL-cysteinyl-glycyl-DL-seryl-DL-histidyl-DL-leucyl-DL-valyl-DL-alpha-glutamyl-DL-alanyl-DL-leucyl-DL-tyrosyl-DL-leucyl-DL-valyl-DL-cysteinyl-glycyl-DL-alpha-glutamyl-DL-arginyl-glycyl-DL-phenylalanyl-DL-phenylalanyl-DL-tyrosyl-DL-threonyl-DL-alpha-aspartyl-DL-lysyl-DL-threonine (7->7'),(19->20')-bis(disulfide) compound with glycyl-DL-isoleucyl-DL-valyl-DL-alpha-glutamyl-DL-glutaminyl-DL-cysteinyl-DL-cysteinyl-DL-threonyl-DL-seryl-DL-isoleucyl-DL-cysteinyl-DL-seryl-DL-leucyl-DL-tyrosyl-DL-glutaminyl-DL-leucyl-DL-alpha-glutamyl-DL-asparagyl-DL-tyrosyl-DL-cysteinyl-DL-asparagine (6'->11')-disulfide; H-DL-Phe-DL-Val-DL-Asn-DL-Gln-DL-His-DL-Leu-DL-Cys(1)-Gly-DL-Ser-DL-His-DL-Leu-DL-Val-DL-Glu-DL-Ala-DL-Leu-DL-Tyr-DL-Leu-DL-Val-DL-Cys(2)-Gly-DL-Glu-DL-Arg-Gly-DL-Phe-DL-Phe-DL-Tyr-DL-xiThr-DL-Asp-DL-Lys-DL-xiThr-OH.H-Gly-DL-xiIle-DL-Val-DL-Glu-DL-Gln-DL-Cys(3)-DL-Cys(1)-DL-xiThr-DL-Ser-DL-xiIle-DL-Cys(3)-DL-Ser-DL-Leu-DL-Tyr-DL-Gln-DL-Leu-DL-Glu-DL-Asn-DL-Tyr-DL-Cys(2)-DL-Asn-OH. CAS No. 116094-23-6. Pack Sizes: 25 mg. Product ID: BAT-016096. Molecular formula: C256H381N65O79S6. Mole weight: 5825.53. Custom synthesis is availab |  London |
| 2,2-dimethyldodecanoic Acid | 2,2-Dimethyldodecanoic acid, an intriguing biochemical, has emerged as a promising therapeutic candidate for the treatment of neurological disorders and diabetes. As a modulator of the mitochondrial membrane, this compound has garnered attention for its ability to enhance insulin sensitivity and glucose tolerance in experimental subjects, showcasing its therapeutic potential in metabolic disorders. Furthermore, preclinical investigations have yielded encouraging results, highlighting its potential to serve as a potent anxiolytic and antidepressant agent, rendering it a prime target for future research. Group: Pharmaceutical. Alternative Names: 2,2-dimethyllauric acid. CAS No. 2874-73-9. Pack Sizes: 10 g. Product ID: B1370-204330. Molecular formula: C14H28O2. Mole weight: 228.37. Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Aminophenyl a-D-mannopyranoside 6-phosphate | 4-Aminophenyl a-D-mannopyranoside 6-phosphate is a chemical compound used in the synthesis of phosphoinositide. This product is also used in the study of phosphatidylinositol (PI) signaling pathways, and has been shown to inhibit phospholipase C activity. Additionally, it has been found to be involved in the regulation of insulin secretion. Group: Pharmaceutical. Alternative Names: 4-Aminophenyl 6-phospho-alpha-mannopyranoside; 4-Aminophenyl 6-phospho-alpha-D-mannopyranoside. CAS No. 74160-60-4. Pack Sizes: 100 mg. Product ID: B1370-000873. Molecular formula: C12H18NO9P. Mole weight: 351.25. Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Hydroxyisoleucine | 4-Hydroxyisoleucine, which comes from the seeds of Trigonella foenum-graecum L, could inhibit palmitate-induced, ROS-associated inflammation and restored insulin sensitivity through regulating IRS-1 function. It acts to improve insulin resistance by promoting mitochondrial biogenesis in high fructose diet fed STZ induced diabetic rats. Besides, 4-Hydroxyisoleucine could remarkably improve high glucose-induced IR in 3T3-L1 adipocytes. Meanwhile, 4-HIL could inhibit the secretion of TNF-alpha. Group: Pharmaceutical. Alternative Names: 4-HYDROXY-L-ISOLEUCINE; (2S,3R)-2-aMino-4-hydroxy-3-Methylpentanoic acid. CAS No. 781658-23-9. Pack Sizes: 100 mg. Product ID: B0005-347850. Molecular formula: C6H13NO3. Mole weight: 147.17. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-[(2,4-Dichlorophenyl)methylidene]-1,3-thiazolidine-2,4-dione | 5-[(2,4-Dichlorophenyl)methylidene]-1,3-thiazolidine-2,4-dione is a potential PPAR agonist with antibacterial, antidiabetic and antioxidant activities. The esteemed 5-[(2,4-Dichlorophenyl)methylidene]-1,3-thiazolidine-2,4-dione is a highly efficacious agent utilized in the management of type 2 diabetes mellitus. By enhancing insulin secretion and suppressing hepatic glucose output, it diligently lowers blood glucose concentrations, thereby promoting normoglycemia. Its demonstrated efficacy and mechanism of action render it an alluring therapeutic option for those with the aforementioned condition. Group: Pharmaceutical. Alternative Names: NSC 31150; Antimicrobial agent-33. CAS No. 51244-45-2. Pack Sizes: 50 mg. Product ID: B0001-284765. Molecular formula: C10H5Cl2NO2S. Mole weight: 274.115. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-[(2-Hydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione | 5-[(2-Hydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione, a chemical compound with potential therapeutic applications in diabetes and related metabolic disorders, exhibits insulin sensitizing properties that are aimed at lowering high-blood glucose levels and enhancing insulin sensitivity. Remarkably, this compound also has antioxidant and anti-inflammatory functions, which manifest its suitability in treating ailments associated with inflammation and oxidative stress. Therefore, it stands a good chance as a candidate for the treatment of various diseases with such pathological features. Group: Pharmaceutical. Alternative Names: 2,4-Thiazolidinedione, 5-[(2-hydroxyphenyl)methylene]-. CAS No. 6325-94-6. Pack Sizes: 50 mg. Product ID: B0001-284762. Molecular formula: C10H7NO3S. Mole weight: 221.23. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-[(3,4-Dimethoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione | 5-[(3,4-Dimethoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione, a small molecule guanidine compound, exerts hypoglycemic effects in treating diabetes mellitus. The compound's hypoglycemic action is attributed to its capacity to augment insulin sensitivity as well as the uptake of glucose within cellular organelles. Group: Pharmaceutical. Alternative Names: 5-(3,4-dimethoxybenzylidene)-1,3-thiazolidine-2,4-dione. CAS No. 6325-95-7. Pack Sizes: 50 mg. Product ID: B0001-284770. Molecular formula: C12H11NO4S. Mole weight: 265.283. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-[(4-Hydroxy-3-methoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione | The compound 5-[(4-Hydroxy-3-methoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione finds applications in the biomedical domain as an antidiabetic medication. Its potential as an activator of the peroxisome proliferator-activated receptor gamma (PPARγ) has been acknowledged, presenting a promising approach towards the regulation of glucose metabolism and insulin sensitivity within the body. With demonstrated efficacy in the management of type 2 diabetes mellitus and associated complications, this synthetic compound presents a potential solution to this chronic condition. Group: Pharmaceutical. Alternative Names: Kinome_3045. CAS No. 24044-50-6. Pack Sizes: 50 mg. Product ID: B0001-284767. Molecular formula: C11H9NO4S. Mole weight: 251.256. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-[Methylidene]thiazolidine-2,4-dione | 5-[Methylidene]thiazolidine-2,4-dione, a thiazolidinedione derivative, exhibits remarkable pharmaceutical potential in tackling diabetes via targeting the PPAR-γ protein responsible for maintaining glucose homeostasis. The efficacious drug candidate has demonstrated promising outcomes in ameliorating insulin resistance and alleviating hyperglycemia in diverse diabetes animal models, thus rendering it a potential therapeutic agent for diabetes management. Group: Pharmaceutical. Alternative Names: 5-(2-nitrobenzylidene)-1,3-thiazolidine-2,4-dione. CAS No. 36140-65-5. Pack Sizes: 50 mg. Product ID: B0001-284769. Molecular formula: C10H6N2O4S. Mole weight: 250.228. Custom synthesis is available. Send your inquiries for more information. | London |
| A66 | Inhibition of p110α alone by A66 treatment is sufficient to block insulin signalling to Akt/PKB in certain cell lines that harbor H1047R mutations in PIK3CA and have high levels of p110α and class-Ia PI3K activity. Group: Pharmaceutical. Alternative Names: A66; A-66; A 66. CAS No. 1166227-08-2. Pack Sizes: 1mg;1g;10g. Product ID: 1166227-08-2. Molecular formula: C17H23N5O2S2. Mole weight: 393.53. Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl-Lys5-octreotide Acetate | Acetyl-Lys5-octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Group: Pharmaceutical. Alternative Names: Lys(Ac)-Octreotide Acetate; D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl(acetyl)-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7). Pack Sizes: 10 mg. Product ID: B1370-458987. Molecular formula: C51H68N10O11S2.xC2H4O2. Mole weight: 1061.28 (free base). Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl-Phe1-octreotide Acetate | Acetyl-Phe1-octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Group: Pharmaceutical. Alternative Names: L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanylD-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-, acetate (salt) (9CI); Ac-D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); N-Acetyl-Phe-Octreotide Acetate. CAS No. 83795-62-4. Pack Sizes: 10 mg. Product ID: B1370-458988. Molecular formula: C51H68N10O11S2.xC2H4O2. Mole weight: 1061.28 (free base). Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Octreotide | Ac-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Group: Pharmaceutical. Alternative Names: Ac-DPhe-Cys-Phe-DTrp-Lys-Thr-Cys-Thr-ol(Cys2&Cys7 bridge); N2.1-Acetyloctreotide; Ac-D-Phe-c(Cys-Phe-D-Trp-Lys-Thr-Cys)-Thr-ol; Octreotide EP Impurity I; Ac-D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); N-Acetyl-Phe-Octreotide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl. CAS No. 83795-61-3. Pack Sizes: 1mg;1g;10g. Product ID: BAT-014620. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28. Custom synthesis is available. Send your inquiries for more information. | London |
| Amylin (human) | Amylin, islet Amyloid Polypeptide (IAPP), is a 37-residue peptide hormone secreted by pancreatic β-cells. It inhibits insulin-stimulated glucose uptake, delays gastric emptying and promotes satiety. It has glucose lowering effects in vivo. It is also used to study the mechanisms of amyloid deposition and its role in molecular misfolding processes expecially in conditions such as diabetes type II. Group: Pharmaceutical. Alternative Names: L-Tyrosinamide, L-lysyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-seryl-L-asparaginyl-L-asparaginyl-L-phenylalanylglycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-seryl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-asparaginyl-L-threonyl-, cycl. CAS No. 122384-88-7. Pack Sizes: 1 mg. Product ID: BAT-006084. Molecular formula: C165H261N51O55S2. Mole weight: 3903.33. Custom synthesis is available. Send your inquiries for more information. | London |
| Azoramide | Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It is a dual-function endoplasmic reticulum (ER) modulator in vitro. It improves endoplasmic reticulum (ER) protein-folding ability and stimulates the expression of ER chaperones to protect cells against ER stress in multiple systems. It regulates ER folding and secretion capacity without inducing ER stress. It might have the protective effects of enhancing chaperone expression and reducing protein synthesis without inducing cytotoxicity and apoptosis. It showed potent antidiabetic activity in two independent mouse models of obesity by protecting pancreatic β cell function against ER stress and improving insulin sensitivity in vivo. It improves glucose homeostasis in mice with genetic obesity and diet-induced obesity. Group: Pharmaceutical. Alternative Names: N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]butanamide. CAS No. 932986-18-0. Pack Sizes: 100 mg. Product ID: B1370-474920. Molecular formula: C15H17ClN2OS. Mole weight: 308.82. Custom synthesis is available. Send your inquiries for more information. | London |
| β-Nicotinamide Mononucleotide | β-Nicotinamide mononucleotide, a major product of extracellular NAMPT reaction, could ameliorate glucose intolerance and also increase hepatic insulin sensitivity and sorts of gene expression involved in inflammatory response, oxidative stress and so on. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-, inner salt; 3-Carbamoyl-1-β-D-ribofuranosylpyridinium hydroxide, 5'-phosphate, inner salt; Pyridinium, 3-carbamoyl-1-β-D-ribofuranosyl-, hydroxide, 5'-(dihydrogen phosphate), inner salt; Nicotinamide mononucleotide; Nicotinamide ribonucleoside 5'-phosphate; Nicotinamide ribonucleotide; Nicotinamide ribotide; NMN; NMN (mononucleotide); β-D-NMN; β-NMN. CAS No. 1094-61-7. Pack Sizes: 5 g. Product ID: B0084-245647. Molecular formula: C11H15N2O8P. Mole weight: 334.22. Custom synthesis is available. Send your inquiries for more information. | London |
| Bi-linderone | Bi-linderone is a natural miscellaneou found in the roots of Lindera aggregata( Sims) Kosterm, it shows significant activity against glucosamine-induced insulin resistance in HepG2 cells at a concentration of 1 microg/mL. Group: Pharmaceutical. CAS No. 1227375-09-8. Pack Sizes: 1 mg. Product ID: NP4323. Molecular formula: C34H32O10. Mole weight: 600.6. Custom synthesis is available. Send your inquiries for more information. | London |
| BMS-536924 | BMS-536924 is a potent small molecule inhibitor of IGF-IR, which shows antitumor activity in multiple tumor models, including sarcoma. Group: Pharmaceutical. Alternative Names: BMS536924; BMS 536924; Insulin-like Growth Factor-1 Receptor Inhibitor; (S)-4-((2-(3-chlorophenyl)-2-hydroxyethyl)amino)-3-(4-methyl-6-morpholino-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one. CAS No. 468740-43-4. Pack Sizes: 50 mg. Product ID: B1370-142616. Molecular formula: C25H26ClN5O3. Mole weight: 479.96. Custom synthesis is available. Send your inquiries for more information. | London |
| Bruceine E | Bruceine E is extracted from the seeds of Brucea javanica (L.) Merr. It could reduce blood glucose concentration remarkably and may be used as an insulin secretagogue. Group: Pharmaceutical. Alternative Names: 13,20-Epoxy-1β,2α,11β,12α,14,15β-hexahydroxypicras-3-en-16-one; 20-Deoxybruceine F; 2-O-Demethylbruceine M; 5H-3,11c-beta-(Epoxymethano)phenanthro(10,1-bc)pyran-5-one, 1,2,3,3a,4,6a-beta,7,7a-alpha,10,11,11a,11b-alpha-dodecahydro-1-beta,2-alpha,3a-beta,4-beta,10-alpha,11-beta-hexahydroxy-3-alpha,8,11a-beta-trimethyl-, (+)-; Picras-3-en-16-one, 13,20-epoxy-1,2,11,12,14,15-hexahydroxy-, (1beta,2alpha,11beta,12alpha,15beta)-. CAS No. 21586-90-3. Pack Sizes: 1 mg. Product ID: NP1578. Molecular formula: C20H28O9. Mole weight: 412.43. Custom synthesis is available. Send your inquiries for more information. | London |
| Chrysin-7-O-glucuronide | Chrysin-7-O-glucuronide, a flavone compound derived from plants, has garnered attention for its therapeutic potential against cancer and diabetes. Prior investigations have demonstrated its ability to modulate the apoptotic pathways in cancer cells, leading to growth inhibition and reduced tumor progression. Furthermore, chrysin-7-O-glucuronide exhibits promising attributes as a glucose regulator, as evidenced by its capacity to enhance insulin sensitivity and support proper glucose metabolism. These findings collectively suggest chrysin-7-O-glucuronide as a worthy candidate for further exploration in the development of cancer and diabetes treatment. Group: Pharmaceutical. Alternative Names: Chrysin-7-glucoronide; Chrysin-7-O-Beta-D-glucoronide; Chrysin-7-O-β-D-glucoronide; Chrysin 7-O-beta-D-glucopyranuronoside. CAS No. 35775-49-6. Pack Sizes: 5 mg. Product ID: B2703-001241. Molecular formula: C21H18O10. Mole weight: 430.36. Custom synthesis is available. Send your inquiries for more information. | London |
| Cosmosiin | Cosmosiin also called Apigenin 7-O-glucoside, is a natural flavonoid found in the flowers of Cosmos bipinnatus. Cosmosiin exhibits the activities of anti-HIV, anti-proliferative and antioxidant, the compound may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 translocation. Uses: Anti-proliferative; antioxidant; anti-hiv. Group: Pharmaceutical. Alternative Names: Apigenin 7-O-glucoside. CAS No. 578-74-5. Pack Sizes: 20 mg. Product ID: NP1892. Molecular formula: C21H20O10. Mole weight: 432.39. Custom synthesis is available. Send your inquiries for more information. | London |
| CP-640186 | CP-640186 is a potent inhibitor of mammalian ACCs and can reduce body weight and improve insulin sensitivity in test animals. It has recently been shown to be a potent inhibitor of isoforms of mammalian ACCs. Most importantly, CP-640186 can reduce body fat mass and body weight, and improve insulin sensitivity, validating ACCs as targets for antiobesity and antidiabetes drugs. Group: Pharmaceutical. Alternative Names: CP-640186; CP 640186; CP640186. CAS No. 591778-68-6. Pack Sizes: 100 mg. Product ID: B2693-459321. Molecular formula: C30H35N3O3. Mole weight: 485.62. Custom synthesis is available. Send your inquiries for more information. | London |
| (Cys(S)²)-Octreotide trifluoroacetate salt | Trisulfide Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Group: Pharmaceutical. Alternative Names: H-D-Phe-Cys(S)-Phe-D-Trp-Lys-Thr-Cys-L-threoninol trifluoroacetate salt (Trisulfide bond); Trisulfide Octreotide trifluoroacetate salt. Pack Sizes: 10 mg. Product ID: B1370-449815. Custom synthesis is available. Send your inquiries for more information. | London |
| D-allo-Thr(6)-Octreotide | D-allo-Thr(6)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Group: Pharmaceutical. Alternative Names: DPhe-Cys-Phe-DTrp-Lys-DaThr-Cys-Thr-ol(Cys2&Cys7 bridge); [6-D-allothreonine]octreotide; DPhe-CF-DTrp-K-DaThr-C-Thr-ol(Cys2&Cys7 bridge); Octreotide EP Impurity A; (D-Phe)-Cys-Phe-(D-Trp)-Lys-(Dallo-Thr)-Cys-Thr-Ol (Disulfide bond Cys2/Cys7); D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-allo-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); D-Phe-Cys-Phe-D-Trp-Lys-D-allo-Thr-Cys-Thr-ol (Disulfide Bridge between Cys2-Cys7); Octreotide impurity A; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-allo-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide. CAS No. 1546983-12-3. Pack Sizes: 1mg;1g;10g. Product ID: BAT-017067. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25. Custom synthesis is available. Send your inquiries for more information. | London |
| D-allo-Thr(6)-Octreotide trifluoroacetate salt | D-allo-Thr(6)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B1370-449814. Custom synthesis is available. Send your inquiries for more information. | London |
| DCPIB | DCPIB is a potent and selective volume-sensitive anion channel (VSAC) blocker, swell in various cardiovascular tissues (IC50 = 4.1 μM in CPAE cells). It inhibits glucose-stimulated insulin in intact β-cells, and reverses cell swelling-induced action potential duration shortening in atrial myocytes and inhibits astroglial swelling in vitro. Group: Pharmaceutical. Alternative Names: 4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]butanoic acid. CAS No. 82749-70-0. Pack Sizes: 50 mg. Product ID: B2693-034500. Molecular formula: C22H28Cl2O4. Mole weight: 427.37. Custom synthesis is available. Send your inquiries for more information. | London |
| D-Cys(2)-Octreotide trifluoroacetate salt | D-Cys(2)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Group: Pharmaceutical. Alternative Names: H-D-Phe-D-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol trifluoroacetate salt (Disulfide bridge: Cys2-Cys7); Octreotide EP Impurity G trifluoroacetate salt. Pack Sizes: 10 mg. Product ID: B1370-449817. Custom synthesis is available. Send your inquiries for more information. | London |
| D-Cys(7)-Octreotide | D-Cys(7)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Group: Pharmaceutical. Alternative Names: DPhe-Cys-Phe-DTrp-Lys-Thr-DCys-Thr-ol(Cys2&Cys7 bridge); [7-D-cysteine]octreotide; Octreotide EP Impurity B; [D-Cys7]-Octreotide; D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-D-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-D-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); D-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; DPhe-CF-DTrp-KT-DCys-Thr-ol(Cys2&Cys7 bridge). CAS No. 1211530-36-7. Pack Sizes: 10 mg. Product ID: B1370-425645. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25. Custom synthesis is available. Send your inquiries for more information. | London |
| Des-Threoninol-Octreotide | Des-Threoninol-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Group: Pharmaceutical. Alternative Names: DPhe-Cys-Phe-DTrp-Lys-Thr-Cys(Cys2&Cys7 bridge); [Des-Thr-ol] Octreotide; Des-Thr-ol Octreotide; [Des-Thr-ol8] Octreotide; DPhe-CF-DTrp-KTC(Cys2&Cys7 bridge); D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystine (Disulfide Bridge between Cys2-Cys7); Octreotide impurity-11; H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-OH (Disulfide bridge: Cys2-Cys7); L-Cysteine, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-, cyclic (2→7)-disulfide; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteine cyclic (2→7)-disulfide. CAS No. 160841-00-9. Pack Sizes: 1mg;1g;10g. Product ID: BAT-014382. Molecular formula: C45H57N9O9S2. Mole weight: 932.13. Custom synthesis is available. Send your inquiries for more information. | London |
| Dihydroberberine | Dihydroberberine, isolated from the tubers of Corydalis decumbens (Thunb.) Pers, was identified that displayed improved in vivo efficacy in terms of counteracting increased adiposity, tissue triglyceride accumulation, and insulin resistance in high-fat-fed rodents. It is also a potential therapeutic reagent for type 2 diabetes treatment. Uses: Anti-tumor. Group: Pharmaceutical. Alternative Names: 5,8-Dihydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine; 9,10-Dimethoxy-2,3-(methylenedioxy)-13,13a-didehydroberbine; Dihydroumbellatine; 9,10-DiMethoxy-6,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinoline; Dihydroumbellatine. CAS No. 483-15-8. Pack Sizes: 10 mg. Product ID: B2703-465605. Molecular formula: C20H19NO4. Mole weight: 337.36. Custom synthesis is available. Send your inquiries for more information. | London |
| D-Thr(6)-Octreotide Acetate | D-Thr(6)-0ctreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Group: Pharmaceutical. Alternative Names: L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-,cyclic (2→7)-disulfide, [R-(R*,R*)]-, acetate (salt) (9CI). CAS No. 87759-90-8. Pack Sizes: 10 mg. Product ID: B1370-449813. Molecular formula: C49H66N10O10S2.xC2H4O2. Custom synthesis is available. Send your inquiries for more information. | London |
| Ehp-inhibitor-1 | Ehp-inhibitor-1 is an Eph family tyrosine kinase inhibitor targeting Eph receptors. Study indicated that inhibition of Eph receptors results in an increase in glucose-stimulated insulin secretion from mouse and human pancreatic islets. Group: Pharmaceutical. Alternative Names: 6-(3-methoxyphenyl)-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine. CAS No. 861249-59-4. Pack Sizes: 50 mg. Product ID: B0084-284759. Molecular formula: C18H15N5O. Mole weight: 317.352. Custom synthesis is available. Send your inquiries for more information. | London |
| Ehp-inhibitor-2 | Ehp-inhibitor-2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors. Study indicated that inhibition of Eph receptors results in an increase in glucose-stimulated insulin secretion from mouse and human pancreatic islets. Group: Pharmaceutical. Alternative Names: 3-(7-amino-3-(pyridin-3-yl)pyrazolo[1,5-a]pyrimidin-6-yl)phenol. CAS No. 861249-77-6. Pack Sizes: 50 mg. Product ID: B0084-284760. Molecular formula: C17H13N5O. Mole weight: 303.325. Custom synthesis is available. Send your inquiries for more information. | London |
| Elafibranor | Elafibranor is a dual PPARα/δ agonist. Elafibranor increases plasma HDL and expression of Acox1, a PPARα target gene, and decreases plasma triglycerides and total cholesterol in the liver of ApoE2-KI wild-type mice. Elafibranor is identified as a drug candidate for the treatment of cardiometabolic diseases such as diabetes, insulin resistance, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD). Group: Pharmaceutical. Alternative Names: Propanoic acid, 2-[2,6-dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methyl-; 2-[2,6-Dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropanoic acid; (E)-1-[4-(Methylthio)phenyl]-3-[3,5-dimethyl-4-[(carboxydimethylmethyl)oxy]phenyl]prop-2-en-1-one; GFT 505; GFT-505; GFT505. CAS No. 923978-27-2. Pack Sizes: 250 mg. Product ID: B0084-074234. Molecular formula: C22H24O4S. Mole weight: 384.49. Custom synthesis is available. Send your inquiries for more information. | London |
| Eriodictyol | Eriodictyol is a natural flavonoid found in the fruits of Citrus sinensis (L.) Osbeck. Eriodictyol exhibits activities of antidiabetic, anti-inflammatory and antioxidant. Eriodictyol can increases glucose uptake and improves insulin resistance. Group: Pharmaceutical. Alternative Names: (S)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4-benzopyrone; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one; 3',4',5,7-tetrahydroxyflavanone; 4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-. CAS No. 552-58-9. Pack Sizes: 10 mg. Product ID: NP2540. Molecular formula: C15H12O6. Mole weight: 288.25. Custom synthesis is available. Send your inquiries for more information. | London |
| Exenatide acetate | Exenatide acetate is a potent peptide agonist of the glucagon-like peptide 1 (GLP-1) receptor with Ki value of 136 pM. It is a 39 amino acid peptide, which increases intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors. It was first isolated from the venom of H. horridum and consequently synthesized. It stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways via a GLP-1 receptor-dependent mechanism. It also stimulates glucose-induced insulin secretion in isolated rat islets and proinsulin expression in mouse insulinoma βTC-1 cells. It protects hippocampal neurons against glutamate-induced apoptosis, suggesting utility in neurodegenerative diseases. It also has anxiolytic and anti-depressant effects and induces satiety. It is an incretin mimetic approved for type 2 diabetes mellitus treatment. It also has neurotrophic/protective activity in cellular and animal models of stroke, Alzheimer's and Parkinson's diseases. Group: Pharmaceutical. Alternative Names: L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L | London |
| Exendin 3 (9-39) | Exendin (9-39) is a specific and competitive glucagon-like peptide-1receptor antagonist (Kd = 1.7 nM at cloned human GLP-1 receptors). Exendin (9-39) inhibits insulin release and cAMP production caused by GLP-1 (7-36), exendin-3, and exendin-4. Group: Pharmaceutical. Alternative Names: Exendin 9-39; Exendin 9 39; H-DL-Asp-DL-Leu-DL-Ser-DL-Lys-DL-Gln-DL-Met-DL-Glu-DL-Glu-DL-Glu-DL-Ala-DL-Val-DL-Arg-DL-Leu-DL-Phe-DL-xiIle-DL-Glu-DL-Trp-DL-Leu-DL-Lys-DL-Asn-Gly-Gly-DL-Pro-DL-Ser-DL-Ser-Gly-DL-Ala-DL-Pro-DL-Pro-DL-Pro-DL-Ser-NH2; DL-alpha-aspartyl-DL-leucyl-DL-seryl-DL-lysyl-DL-glutaminyl-DL-methionyl-DL-alpha-glutamyl-DL-alpha-glutamyl-DL-alpha-glutamyl-DL-alanyl-DL-valyl-DL-arginyl-DL-leucyl-DL-phenylalanyl-DL-isoleucyl-DL-alpha-glutamyl-DL-tryptophyl-DL-leucyl-DL-lysyl-DL-asparagyl-glycyl-glycyl-DL-prolyl-DL-seryl-DL-seryl-glycyl-DL-alanyl-DL-prolyl-DL-prolyl-DL-prolyl-DL-serinamide. CAS No. 133514-43-9. Pack Sizes: 1 mg. Product ID: BAT-006203. Molecular formula: C149H234N40O47S. Mole weight: 3369.76. Custom synthesis is available. Send your inquiries for more information. | London |
| FOXO4-DRI | FOXO4-DRI is a peptide acting as a specific FOXO4 blocker. It has been demonstrated to alleviate age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice.FOXO4-DRI is a peptide acting as a specific FOXO4 blocker. It has been demonstrated to alleviate age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice. FOXO4-DRI is a standard FOXO4 protein that is synthesized to prevent normal FOXO4 from binding to p53, thereby eliminating senescent cells and improving organ function and the ''biological age'' of young tissues. FOXO4-DRI affects a variety of cellular processes, including insulin signaling, cell cycle regulation, and oxidative stress signaling pathways, it is a cell-penetrative peptide, meaning it can enter cells from the inside and perform its role, and it has been shown in animal studies to selectively induce apoptosis in senescence cells, potentially reversing some of the effects of aging. Group: Pharmaceutical. Alternative Names: FOXO 4-DRI; Anti-aging peptide FOXO4-DRI; H-D-Leu-D-Thr-D-Leu-D-Arg-D-Lys-D-Glu-D-Pro-D-Ala-D-Ser-D-Glu-D-Ile-D-Ala-D-Gln-D-Ser-D-Ile-D-Leu-D-Glu-D-Ala-D-Tyr-D-Ser-D-Gln-D-Asn-D-Gly-D-Trp-D-Ala-D-Asn-D-Arg-D-Arg-D-Ser-D-Gly-D-Gly-D-Lys-D-Arg-D-Pro-D-Pro-D-Pro-D-Arg-D-Arg-D-Arg-D-Gln-D-Arg-D-Arg-D-Lys-D-Lys-D-Arg-D-Gly-OH; Forkhead box O transcription factor 4-D-Retro-Inverso; Proxofim; D-Retro Inv. CAS No. 2460055 | London |
| Genistein | Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM. Genistein is developed to be an antitumor agent. Genistein has antioxidant effect, it can be used in cosmetics material. It is a plant polyphenol that can inhibit tyrosinase, block melanin synthesis, reduce skin pigment intensity, absorb UV, prevent photoaging, reduce sun damage and age spot formation, and whiten and lighten spots. It also has the anti-glycation and antibacterial effect, can effectively improve skin tone and skin texture, prevent the generation of age spots, remove red bloodlines, and improve skin blood microcirculation. Uses: Antitumor agent. Group: Pharmaceutical. Alternative Names: 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Baichanin A; Bonistein; 4',5,7-Trihydroxyisoflavone; GeniVida; Genisteol; NSC 36586; Prunetol; Sophoricol; Differenol A. CAS No. 446-72-0. Pack Sizes: 5 g. Product ID: BBF-01840. Molecular formula: C15H10O5. Mole weight: 270.24. Custom synthesis is available. Send your inquiries for more information. | London |
| GIP (human) | GIP (human) is a potent insulinotropic hormone synthesized by duodenal K-cells. It inhibits gastric acid secretion and stimulates pancreatic insulin release in response to glucose. Group: Pharmaceutical. Alternative Names: Gastric Inhibitory Polypeptide human; Gastric Inhibitory Polypeptide (human); Gastric Inhibitory Peptide (GIP), human; Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln. CAS No. 100040-31-1. Pack Sizes: 1 mg. Product ID: BAT-006165. Molecular formula: C226H338N60O66S. Mole weight: 4983.58. Custom synthesis is available. Send your inquiries for more information. | London |
| Gliclazide EP Impurity B | An impurity of Gliclazide. Gliclazide is a second-generation sulfonylurea oral antidiabetic medication primarily used to treat type 2 diabetes by stimulating insulin secretion from pancreatic beta cells and reducing hepatic glucose production. Group: Pharmaceutical. Alternative Names: N-Nitroso gliclazide impurity B; Gliclazide Impurity B; 2-Nitroso-octahydrocyclopenta[c]pyrrole; Octahydro-2-nitrosocyclopenta[c]pyrrole; N-Nitroso-3-azabicyclo[3.3.0]octane; 3-Nitroso-3-azabicyclo[3.3.0]octane; N-Nitroso Gliclazide EP Impurity B. CAS No. 54786-86-6. Pack Sizes: 100 mg. Product ID: B1370-440025. Molecular formula: C7H12N2O. Mole weight: 140.19. Custom synthesis is available. Send your inquiries for more information. | London |
| Glimepiride | Glimepiride is a medium to long-acting sulfonylurea antidiabetic drug. It acts by stimulating the insulin release from pancreatic β-cells and decreases glucose output from the liver. Group: Pharmaceutical. Alternative Names: Amaryl; Glimepirid; Amarel; HOE 490; 1-[[p-[2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea. CAS No. 93479-97-1. Pack Sizes: 10 g. Product ID: NP3448. Molecular formula: C24H34N4O5S. Mole weight: 490.62. Custom synthesis is available. Send your inquiries for more information. | London |
| GLP-1(7-36) amide | GLP-1(7-36) amide is a glucose-dependent insulinotropic peptide displaying high affinity for GLP-1 receptors expressed in rat insulinoma-derived RINm5F cells (Kd = 204 pM). GLP-1 (7-36) amide exhibits antiapoptotic effects in hippocampal neurons and reduces food intake in fasted rats following central administration. Group: Pharmaceutical. Alternative Names: GLP-1; GLP-1 (7-36) amide; Insulinotropin. CAS No. 107444-51-9. Pack Sizes: 1 mg. Product ID: BAT-006200. Molecular formula: C149H226N40O45. Mole weight: 3297.67. Custom synthesis is available. Send your inquiries for more information. | London |
| GLP-1(7-37) | GLP-1 (7-37) is an insulinotropic peptide generated from the precursor peptide GLP-1 (1-37). It is a potent stimulator of insulin secretion at concentrations as low as 5 X 10(-11) M and has no effect on insulin secretion even at concentrations as high as 5 X 10(-7) M. It participates in the physiological regulation of insulin secretion. Uses: Glp-1 (7-37) acetate participates in the physiological regulation of insulin secretion. Group: Pharmaceutical. Alternative Names: Proglucagon (78-108) (human, bovine, guinea pig, mouse, rat); Insulinotropin (human, bovine, guinea pig, mouse, rat); Glucagon-Like Peptide 1 (7-37) (human, bovine, guinea pig, mouse, rat); Preproglucagon (98-128) (human, bovine, guinea pig, mouse, rat); GLP-1 (7-37) human; Glucagon-like Peptide-1 (7-37); H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH; L-histidyl-L-alanyl-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-glycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysyl-glycyl-L-arginyl-glycine. CAS No. 106612-94-6. Pack Sizes: 1 mg. Product ID: BAT-006116. Molecular formula: C151H228N40O47. Mole weight: 3355.67. Custom synthesis is available. Send your inquiries for more information. | London |
| GLP-1 TFA | GLP-1 is a potent insulin secretagogue that has multiple synergetic effects on the glucose-dependent insulin secretion pathways of the beta-cell. Group: Pharmaceutical. Alternative Names: GLP-1 trifluoroacetate salt; Glucagon-like peptide 1 trifluoroacetate salt; H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2.TFA. Pack Sizes: 25 mg. Product ID: BAT-016125. Custom synthesis is available. Send your inquiries for more information. | London |
| Glucagon-like peptide 1 (1-37), human | Glucagon-like peptide 1 (1-37) is a pancreatic hormone synthesized by post-translational processing of proglucagon. It decreases plasma glucose level in high-fat-fed mice when administered at 25 nmol/kg. Glucagon-like peptide 1 (1-37) exhibits no effect on food intake in rats and does not enhance pancreatic insulin secretion. However it induces insulin expression in intestinal epithelial cells, which can restore glucose homeostasis when implanted into diabetic mice. Group: Pharmaceutical. Alternative Names: HuGLP-1; GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat); Preproglucagon (92-128) (human, bovine, guinea pig, mouse, rat); H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH; L-histidyl-L-alpha-aspartyl-L-alpha-glutamyl-L-phenylalanyl-L-alpha-glutamyl-L-arginyl-L-histidyl-L-alanyl-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-glycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysyl-glycyl-L-arginyl-glycine. CAS No. 87805-34-3. Pack Sizes: 5 mg. Product ID: BAT-010492. Molecular formula: C186H275N51O59. Mole weight: 4169.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Guanosine 3',5'-cyclic monophosphate | Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'-and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. 3',5'-cyclic GMP is a 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine. It has a role as a plant metabolite, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a guanyl ribonucleotide and a 3',5'-cyclic purine nucleotide. It is a conjugate acid of a 3',5'-cyclic GMP(1-). Group: Pharmaceutical. Alternative Names: 3:5-CGMP; D-Guanosine 3',5'-cyclic monophosphate; 3',5'-cyclic GMP; 2-Amino-6-oxo-6,9-dihydro-1H-purine 3-oxide; guanine-3-N-oxide; 2-Amino-1,7-dihydro-6H-purin-6-one 3-oxide; Cyclic guanosine monophosphate. CAS No. 7665-99-8. Pack Sizes: 250 mg. Product ID: B1370-013547. Molecular formula: C10H12N5O7P. Mole weight: 345.21. Custom synthesis is available. Send your inquiries for more information. | London |
| GW9508 | GW9508 is a potent and selective agonist for FFA1 (GPR40) with pEC50 of 7.32, 100-fold selective against GPR120, and stimulates insulin secretion in a glucose-sensitive manner. GW9508 is commonly used in the treatment of type 2 diabetes. Group: Pharmaceutical. Alternative Names: GW9508; GW-9508; GW 9508; 3-(4-((3-Phenoxybenzyl)amino)phenyl)propanoic acid. CAS No. 885101-89-3. Pack Sizes: 100 mg. Product ID: B0084-272136. Molecular formula: C22H21NO3. Mole weight: 347.414. Custom synthesis is available. Send your inquiries for more information. | London |
| Homoplantaginin | Homoplantaginin is a flavonoid glycoside found in Scoparia dulcis. Homoplantaginin ameliorates endothelial insulin resistance by inhibiting inflammation and modulating cell signalling via the IKKβ/IRS-1/pAkt/peNOS pathway, suggesting it may be used for the prevention and treatment of endothelial dysfunction associated with insulin resistance. Group: Pharmaceutical. Alternative Names: 5-hydroxy-2-(4-hydroxyphenyl)-6-methoxy-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside. CAS No. 17680-84-1. Pack Sizes: 25 mg. Product ID: B2703-465489. Molecular formula: C22H22O11. Mole weight: 462.4. Custom synthesis is available. Send your inquiries for more information. | London |
| IGF-1 LR3 | IGF-1 LR3 is a lengthened analogue of human insulin-like growth factor 1 (IGF-1). Group: Pharmaceutical. Alternative Names: Long R3-IGF-1; IGF-1 Long R3; Long arginine 3-IGF-1. CAS No. 946870-92-4. Pack Sizes: 5 mg. Product ID: BAT-006251. Molecular formula: C400H625N111O115S9. Mole weight: 9117.6. Custom synthesis is available. Send your inquiries for more information. | London |
| IXA4 | IXA4 is a highly selective and non-toxic IRE1/XBP1s activator, which activates the IRE1/XBP1s signaling, regardless of the global activation of the unfolded protein response (UPR) or other stress-responsive signaling pathways, such as heat shock response or oxidative stress response. IXA4 reduces APP secretion by activating IRE1. IXA4 therapy improves systemic glucose metabolism and hepatic insulin action through IRE1-dependent liver transcriptomic remodeling, thereby reducing glucose production and steatosis. IXA4-stimulated IRE1 activation also enhances pancreatic function. Group: Pharmaceutical. Alternative Names: N-(1-(2-(methyl(2-(p-tolyloxy)ethyl)amino)-2-oxoethyl)-1H-pyrazol-4-yl)-3-phenoxypropanamide; 1H-Pyrazole-1-acetamide, N-methyl-N-[2-(4-methylphenoxy)ethyl]-4-[(1-oxo-3-phenoxypropyl)amino]-. CAS No. 1185329-96-7. Pack Sizes: 100 mg. Product ID: B1370-382267. Molecular formula: C24H28N4O4. Mole weight: 436.5. Custom synthesis is available. Send your inquiries for more information. | London |
| KIRA6 | KIRA6 allosterically inhibits IRE1α RNase kinase activity in vivo and promotes cell survival under ER stress. Systemically, KIRA6 preserves pancreatic β cells, increases insulin, and reduces hyperglycemia in Akita diabetic mice. Group: Pharmaceutical. Alternative Names: KIRA6; KIRA-6; KIRA 6; 1-[4-(8-amino-3-tert-butylimidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl]-3-[3-(trifluoromethyl)phenyl]urea; 1-(4-(8-amino-3-(tert-butyl)imidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl)-3-(3-(trifluoromethyl)phenyl)urea; KIRA analog, 2. CAS No. 1589527-65-0. Pack Sizes: 20 mg. Product ID: B0084-007192. Molecular formula: C28H25F3N6O. Mole weight: 518.53. Custom synthesis is available. Send your inquiries for more information. | London |
| Linderaspirone A | Linderaspirone A, that is extracted from the roots of Lindera aggregata( Sims) Kosterm, showed significant activity against glucosamine-induced insulin resistance. Group: Pharmaceutical. Alternative Names: (8R,16R)-rel-2,3,6,11,12,14-Hexamethoxy-8,16-diphenyldispiro[4.3.4.3]hexadeca-2,6,11,14-tetraene-1,4,10,13-tetrone. CAS No. 1235126-46-1. Pack Sizes: 1 mg. Product ID: NP4320. Molecular formula: C34H32O10. Mole weight: 600.6. Custom synthesis is available. Send your inquiries for more information. | London |
| Liraglutide-[d4] | Liraglutide-[d4] is the labelled analogue of Liraglutide. Liraglutide activates AMP-activated protein kinase thus enhancing insulin sensitivity, is the long-acting analogue of glucagon-like peptide-1 (GLP-1) receptor which could protect b-cells from apoptosis under conditions associated with the development of type 1 and type 2 diabetes. Group: Pharmaceutical. Alternative Names: L-Histidyl-L-alanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginyl-glycine-d4; Liraglutide D4. Pack Sizes: 10 mg. Product ID: BLP-004354. Molecular formula: C172H261D4N43O51. Mole weight: 3755.23. Custom synthesis is available. Send your inquiries for more information. | London |
| L-Phe(1)-Octreotide trifluoroacetate salt | L-Phe(1)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Group: Pharmaceutical. Alternative Names: H-L-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol trifluoroacetate salt (Disulfide bridge: Cys2-Cys7). Pack Sizes: 10 mg. Product ID: B1370-449818. Custom synthesis is available. Send your inquiries for more information. | London |
| L-Threoninol(Ac)-8-Octreotide | L-Threoninol(Ac)-8-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Group: Pharmaceutical. Alternative Names: DPhe-Cys-Phe-DTrp-Lys-Thr-Cys-Thr-ol-Ac(Cys2&Cys7 bridge); DPhe-CF-DTrp-KTC-Thr-ol-Ac(Cys2&Cys7 bridge); O1.8-Acetyloctreotide; Octreotide EP Impurity F; D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L(Acetyl)-threoninol (Disulfide Bridge between Cys2-Cys7); Octreotide Impurity F; H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Ac-Thr-ol (Disulfide bridge: Cys2-Cys7); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[1-[(acetyloxy)methyl]-2-hydroxypropyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-; O-Acetyl Octreotide; [O1(AC)]8-Octreotide; (L-Threoninol(Ac)8)-Octreotide. CAS No. 133304-81-1. Pack Sizes: 1mg;1g;10g. Product ID: BAT-014748. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28. Custom synthesis is available. Send your inquiries for more information. | London |
| L-Threoninol(Ac)-8-Octreotide trifluoroacetate salt | Threoninol(Ac)-8-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Group: Pharmaceutical. Alternative Names: H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Ac-Thr-ol trifluoroacetate salt (Disulfide bridge: Cys2-Cys7); O-Acetyl Octreotide trifluoroacetate salt. Pack Sizes: 10 mg. Product ID: B1370-449816. Custom synthesis is available. Send your inquiries for more information. | London |
| Lys(Ac)-Octreotide | Lys(Ac)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Uses: Radiopharmaceuticals. Group: Pharmaceutical. Alternative Names: DPhe-Cys-Phe-DTrp-Lys(Ac)-Thr-Cys-Thr-ol(Cys2&Cys7 bridge); N6.5-Acetyloctreotide; D-Phe-c(Cys-Phe-D-Trp-Lys(Ac)-Thr-Cys)-Thr-ol; Lys(Ac) 5 Octreotide; D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl(acetyl)-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-N6-acetyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-N6-acetyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2→7)-disulfide; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-N6-acetyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-; Octreotide EP Impurity H; Octreotide Impurity H; Acetyl-Lys5-octreotide; D-Phenylalanyl-L-hemicystyl-L-phenylalanyl-D-tryptophyl-(N-acetyl)-L-lysyl-L-threonyl-L-hemicystyl-L-threoninol cyclic (2→7)-disulfide. CAS No. 173606-11-6. Pack Sizes: 1mg;1g;10g. Product ID: BAT-014750. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28. Custom synthes | London |
| Mazdutide acetate | Mazdutide acetate is a long-acting glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist. Mazdutide acetate stimulates insulin secretion from mouse pancreatic islets, and can be used in studies of obesity and type 2 diabetes (T2D). Group: Pharmaceutical. Alternative Names: OXM-3 acetate; LY-3305677 acetate; IBI-362 acetate. Pack Sizes: 10 mg. Product ID: B1370-449766. Custom synthesis is available. Send your inquiries for more information. | London |
| MBX-2982 | MBX-2982 is a potential first-in-class treatment for type 2 diabetes that targets G protein-coupled receptor 119 (GPR119), a receptor that interacts with bioactive lipids known to stimulate glucose-dependent insulin secretion. Preclinical data indicate that MBX-2982 is a potent selective orally-active GPR119 agonist that functions through a unique dual mechanism of action. First, it acts directly on the beta cell to increase insulin secretion. In addition, MBX-2982 stimulates release of the incretin GLP-1 from the gut. This dual action is unique and may offer improved glucose homeostasis over existing diabetes therapies, with potential for weight loss and improved islet health. Group: Pharmaceutical. Alternative Names: Pyrimidine, MBX-2982; MBX 2982; MBX2982; SAR-260093; SAR260093; SAR 260093; 5-ethyl-2-(4-(4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)-2-thiazolyl)-1-piperidinyl)-; 4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)-2-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yl)thiazole; B5TRY67L51. CAS No. 1037792-44-1. Pack Sizes: 20 mg. Product ID: B0084-456604. Molecular formula: C22H24N8OS. Mole weight: 448.549. Custom synthesis is available. Send your inquiries for more information. | London |
| Mca-(Ala7,Lys(Dnp)9)-Bradykinin trifluoroacetate salt | Mca-(Ala7,Lys(Dnp)9)-Bradykinin is a very sensitive internally quenched fluorescent substrate for endothelin-converting enzyme-1 (ECE-1), a membrane-bound zinc metallopeptidase related to neprilysin in amino acid sequence. It is used as a substrate for insulin-degrading enzymes (IDE) and ACE2. Group: Pharmaceutical. Alternative Names: Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH trifluoroacetate salt. Pack Sizes: 10 mg. Product ID: B1370-099097. Molecular formula: C68H82F3N15O21. Mole weight: 1502.48. Custom synthesis is available. Send your inquiries for more information. | London |
| MGF | Mechano growth factor (MGF) is a spliced variant of insulin-like growth factor 1 (IGF-1). IGF-1 is found in various tissues in the body including liver and muscle. Group: Pharmaceutical. Alternative Names: MGF E-domain; IGF-1 EC; Mechano Growth Factor. Pack Sizes: 5 mg. Product ID: BAT-006153. Molecular formula: C121H199N40O40. Mole weight: 2868.19. Custom synthesis is available. Send your inquiries for more information. | London |
| Mogroside V | Mogroside V is extracted from the fruit of Siraitia grosvenorii Swingle. It is 300 times sweeter than cane sugar and low in calories. It had a significant effect on insulin secretion and confirmed that the natural sweetener LHK could be beneficial for use by diabetic populations. Studies have found that mogrosides V have strong sweetness and functional effects. Group: Pharmaceutical. Alternative Names: Momordica Extract; (24R)-3β-[6-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyloxy]-24-[2-O,6-O-bis(β-D-glucopyranosyl)-β-D-glucopyranosyloxy]cucurbit-5-ene-11α,25-diol; (3β,9β,10α,11α,24R)-3-[(6-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]-11,25-dihydroxy-9-methyl-19-norlanost-5-en-24-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→6)]-β-D-glucopyranoside; Esgoside. CAS No. 88901-36-4. Pack Sizes: 20 mg. Product ID: NP7008. Molecular formula: C60H102O29. Mole weight: 1287.43. Custom synthesis is available. Send your inquiries for more information. | London |
| MSDC-0160 | MSDC-0160 reduces resistance in the insulin/IGF-1 signaling pathway and restores IGF-1-induced Akt and GSK-3 phosphorylation. Group: Pharmaceutical. Alternative Names: Mitoglitazone; CAY10415; 5-[[4-[2-(5-Ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-2,4-thiazolidinedione; Pioglitazone Ketone; 5-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione; 5-{4-[2-(5-ethylpyridin-2-yl)-2-oxoethoxy]benzyl}-1,3-thiazolidine-2,4-dione. CAS No. 146062-49-9. Pack Sizes: 25 mg. Product ID: B0084-311834. Molecular formula: C19H18N2O4S. Mole weight: 370.42. Custom synthesis is available. Send your inquiries for more information. | London |
| MSDC-0602 | MSDC-0602 is an insulin sensitizer that has the potential to treat diabetes and other inflammatory diseases. It exhibits low affinity for binding and activation of PPARγ. Group: Pharmaceutical. Alternative Names: MSDC-0602; MSDC0602; MSDC 0602; 5-{4-[2-(3-Methoxyphenyl)-2-oxoethoxy]benzyl}-1,3-thiazolidine-2,4-dione; 2,4-Thiazolidinedione, 5-[[4-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl]methyl]-. CAS No. 1133819-87-0. Pack Sizes: 50 mg. Product ID: B0084-284775. Molecular formula: C19H17NO5S. Mole weight: 371.407. Custom synthesis is available. Send your inquiries for more information. | London |
| Octreotide | Octreotide is an inhibitor of growth hormone, glucagon and insulin. It is also an agonist for sst2, sst3 and sst5 somatostatin receptors, hormone-secreting tumors. Uses: The treatment of hormone-secreting tumors, etc. Group: Pharmaceutical. Alternative Names: SMS 201-995; Phe-Cys-Phe-Trp-Lys-Thr-Cys-Thr (Disulfide bridge: Cys2-Cys7); H-D-Phe-Cys(1)-Phe-D-Trp-Lys-Thr-Cys(1)-Thr-ol; D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol (2->7)-disulfide; Sandostatin; Longastatin; [R-(R*,R*)]-D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxy-methyl)propyl]-cysteinamide cyclic(2->7)-disulfide; Samilstin; SMS 201-995. CAS No. 83150-76-9. Pack Sizes: 5 mg. Product ID: BAT-010572. Molecular formula: C49H66N10O10S2. Mole weight: 1019.24. Custom synthesis is available. Send your inquiries for more information. | London |
| Octreotide Acetate | Octreotide acetate is a long-acting octapeptide with pharmacologic actions similars to the natural hormone somatostatin. It is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone. It was approved as an injectable depot formulation used for acromegaly, gigantism, thyrotropinoma, diarrhea and flushing episodes associated with carcinoid syndrome, and diarrhea in patients with vasoactive intestinal peptide-secreting tumors. It is a gastric antisecretory agent andcould inhibit the secretion of insulin and glucagon. It reduces production of IGF-1 and IGF-2 by the liver by modulation of growth-hormone secretion from the pituitary gland. It decreased the urinary excretion of uric acid as well as the plasma concentrations of glucagon and insulin. It decreased the urinary excretion of sodium and chloride without significiant influence on creatinine clearance, while the concentrations of lactic acid, pyruvic acid in blood, and cyclic AMP in plasma were not changed. It was first synthesized in 1979 by the chemist Wilfried Bauer and was developed by Novartis Pharmaceuticals. Uses: Antineoplastic agents, hormonal. Group: Pharmaceutical. Alternative Names: L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, acetate (1:x); H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol.xCH3CO2H (Disulfide B | London |
| PEG-MGF | PEG-MGF is a polyethylene glycol structure attached to a larger mechano growth factor molecule. It is a derived form of the IGF-1 (insulin-like growth factor-1), which stimulates myoblasts division and allows for muscle fibers to fuse and mature. Group: Pharmaceutical. Alternative Names: Pegylated MGF, PEG IGF-1 Ec. Pack Sizes: 10 mg. Product ID: BAT-006258. Molecular formula: C121H200N42O39. Mole weight: 2948.15. Custom synthesis is available. Send your inquiries for more information. | London |
| Peptide YY (3-36) | Peptide YY (3-36) is a Y2/Y5 Neuropeptide Y receptor agonist (IC50= 0.11 nM for inhibition of 125I-PYY binding to Y2 receptor). Human peptide YY (PYY) has roles in energy homeostasis, food ingestion, gut motility and insulin secretion. Group: Pharmaceutical. Alternative Names: Peptide YY (PYY) (3-36), human; H-Ala-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Ser-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2; L-alanyl-L-lysyl-L-prolyl-L-alpha-glutamyl-L-alanyl-L-prolyl-glycyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alanyl-L-seryl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-leucyl-L-seryl-L-arginyl-L-tyrosyl-L-tyrosyl-L-alanyl-L-seryl-L-leucyl-L-arginyl-L-histidyl-L-tyrosyl-L-leucyl-L-asparagyl-L-leucyl-L-valyl-L-threonyl-L-arginyl-L-glutaminyl-L-arginyl-L-tyrosinamide; PYY (3-36) (canine, mouse, porcine, rat). CAS No. 126339-09-1. Pack Sizes: 5 mg. Product ID: BAT-006172. Molecular formula: C176H272N52O54. Mole weight: 3980.42. Custom synthesis is available. Send your inquiries for more information. | London |
| PF-5190457 | PF-5190457 is a selective Growth hormone secretagogue receptor inverse agonist and it can increase insulin secretion in glucose-stimulated human islets. No recent reports of development were reported for phase-I development in Type-2-diabetes-mellitus. Uses: Type 2 diabetes mellitus. Group: Pharmaceutical. Alternative Names: PF-5190457; PF 5190457; PF5190457; PF-05190457; PF05190457; PF 05190457; (R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethan-1-one. CAS No. 1334782-79-4. Pack Sizes: 500 mg. Product ID: B2693-475313. Molecular formula: C29H32N6OS. Mole weight: 512.67. Custom synthesis is available. Send your inquiries for more information. | London |
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