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Inositol Impurities, pivotal in the realm of therapeutic research, significantly influence the development of interventions for mood disorders and metabolic diseases. These impurities facilitate the comprehension of drug stability and efficacy, especially in psychiatric and diabetic medications, thereby bolstering the essential framework for pharmacological advancements. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
D-(+)-chiro-Inositol
1g Pack Size. Group: Biochemicals, Building Blocks, Carbohydrates. Formula: C6H12O6. CAS No. 643-12-9. Prepack ID : 26002642-1g. Molecular Weight : 180.16.
L-alpha-Phosphatidyl inositol
1g Pack Size. Group: Biochemicals. CAS No. 97281-52-2. Prepack ID : 86215300-1g.
Myo-Inositol
Myo-Inositol. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 87-89-8. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications.
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Angiotensin A
Angiotensin A is a potent endogenous vasoconstrictor octapeptide. It is a derivative of angiotensin II (Ang II) that differs from Ang II in having alanine instead of aspartic acid as the first amino acid. It shows similar affinity for AT1 and AT2 receptors as angiotensin II with Ki values of 1.6 and 2.3 nM in vitro. It causes pressor and renal vasoconstrictor effects in rodents by the AT1 receptor. It is inhibited by Candesartan but not by AT2 receptor ligands in vivo. It also increases inositol phosphate accumulation with a similar potency to Ang II with EC50 value of 6.7 nM. Group: Pharmaceutical. CAS No. 51833-76-2. Pack Sizes: 10 mg. Product ID: BAT-015367. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Atosiban
Atosiban, a nonapeptide, desamino-oxytocin analogue, is a competitive inhibitor of the hormones oxytocin and vasopressinv. It inhibits the oxytocin-mediated release of inositol trisphosphate from the myometrial cell membrane. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. It antagonises uterine contractions and induces uterine quiescence in human pre-term labour at the recommended dosage. It was developed by Ferring Pharmaceuticals in Sweden. It is licensed in proprietary and generic forms for the delay of imminent pre-term birth in pregnant adult women. Uses: Atosiban is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Group: Pharmaceutical. CAS No. 90779-69-4. Pack Sizes: 10 mg. Product ID: BAT-010038. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
MKC-3946
MKC-3946 is a potent inhibitor of inositol-requiring enzyme 1α (IRE1α). It inhibits XBP1 mRNA splicing and exhibits cytotoxicity against AML cells. MKC-3946 leads to modest growth inhibition in MM cells but has no effect on normal mononuclear cells in vitro. Group: Pharmaceutical. CAS No. 1093119-54-0. Pack Sizes: 300 mg. Product ID: B0084-054003. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Netupitant
Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively binds to and blocks the human substance P/NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in the prevention of chemotherapy-induced nausea and vomiting (CINV). SP is found in neurons of vagal afferent fibers innervating the brain-stem nucleus tractus solitarii and the area postrema, which contains the chemoreceptor trigger zone (CTZ), and may be elevated in response to chemotherapy. The NK-receptor is a G-protein receptor coupled to the inositol phosphate signal-transduction pathway and is found in both the nucleus tractus solitarii and the area postrema. On 10/10 2014 FDA approved netupitant for the treatment of nausea and vomiting in patients undergoing cancer chemotherapy. Group: Pharmaceutical. CAS No. 290297-26-6. Pack Sizes: 50 mg. Product ID: B2693-465324. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
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