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ALK5 inhibitor II was identified as a cell permeable, selective inhibitor of the TGF-β type 1 activin like kinase receptor ALK5 (ALK5 autophosphorylation, IC50s = 4 nM, TGF-β cellular assay, IC50s = 18 nM, ALK5 binding in HepG2 cells, IC50s = 23 nM). This compound has been used to induce stem cell pluripotency by replacing the reprogramming transcription factor Sox2 via inhibition of the TGF-β signaling pathway and induction of Nanog transcription. This product is a hydrochloride form. Group: Pharmaceutical. CAS No. 446859-33-2. Pack Sizes: 50 mg. Product ID: B0084-068993. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Cathepsin S inhibitor
Cathepsin S is expressed in antigen-presenting cells and plays a role in invariant chain processing and major histocompatibility complex class II (MHCII) antigen presentation leading to CD4+ T-cell activation. An oral Cathepsin S inhibitor that blocks MHCII antigen presentation could result in a T-cell-selective immunosuppressant agent with improved safety over the current standard of care for the treatment of rheumatoid arthritis, psoriasis, multiple sclerosis and other autoimmune-based inflammatory diseases. Group: Pharmaceutical. CAS No. 1373215-15-6. Pack Sizes: 10 mg. Product ID: B0084-463202. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Corrosion Inhibitor
Newport have an equivalent to market leading speciality corrosion inhibitors. After more than 5 years in development and production trials, we are commercially marketing this product to specific clients.
England, Surrey
CTLA-4 inhibitor
CTLA-4 inhibitor is an inhibitor of CTLA-4, an immune checkpoint negatively regulating T cell function. CTLA-4 is thought to regulate T-cell proliferation early in an immune response, primarily in lymph nodes. Group: Pharmaceutical. CAS No. 635324-72-0. Pack Sizes: 10 mg. Product ID: B0084-284810. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Deep Blue Pro - Multifunctional 200g Chlorine Tablets 10 kg Long lasting stabilised clarifier algae inhibitor
These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; chlorine tablets. Grades: A+. Pack Size: 10 kg. Product ID: 0666186536179. MPN: DBPMFTAB2005-1X10kg. Brand: Deep Blue Pro. Categories: Pool Chemicals.
Lincolnshire, Wiltshire, Online
Deep Blue Pro - Multifunctional 200g Chlorine Tablets 1 kg Long lasting stabilised clarifier algae inhibitor
These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; chlorine tablets. Grades: A+. Pack Size: 1 kg. Product ID: 0666186536186. MPN: DBPMFTAB2005-1X1kg. Brand: Deep Blue Pro. Categories: Pool Chemicals.
Lincolnshire, Wiltshire, Online
Deep Blue Pro - Multifunctional 200g Chlorine Tablets 25 kg Long lasting stabilised clarifier algae inhibitor
These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; chlorine tablets. Grades: A+. Pack Size: 25 kg. Product ID: 0666186535660. MPN: DBPMFTAB2005-1X25kg. Brand: Deep Blue Pro. Categories: Pool Chemicals.
Lincolnshire, Wiltshire, Online
Deep Blue Pro - Multifunctional 200g Chlorine Tablets 2 kg Long lasting stabilised clarifier algae inhibitor
These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; chlorine tablets. Grades: A+. Pack Size: 2 kg. Product ID: 0666186536209. MPN: DBPMFTAB2005-1X2kg. Brand: Deep Blue Pro. Categories: Pool Chemicals.
Lincolnshire, Wiltshire, Online
Deep Blue Pro - Multifunctional 200g Chlorine Tablets 5 kg Long lasting stabilised clarifier algae inhibitor
These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; chlorine tablets. Grades: A+. Pack Size: 5 kg. Product ID: 0666186535677. MPN: DBPMFTAB2005-1X5kg. Brand: Deep Blue Pro. Categories: Pool Chemicals.
Lincolnshire, Wiltshire, Online
Deep Blue Pro - Multifunctional 200g Chlorine Tablets x100 20kg Long lasting stabilised clarifier algae inhibitor
These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. These will be sent in multiples of smaller tubs, from 1Kg to 10Kg tubs. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; chlorine tablets. Grades: A+. Pack Size: 20 kg. Product ID: 0666186536193. MPN: DBPMFTAB2005-1X20kg. Brand: Deep Blue Pro. Categories: Pool Chemicals.
Lincolnshire, Wiltshire, Online
Deep Blue Pro - Multifunctional Mini 20g Chlorine Tablets 1kg Long lasting stabilised clarifier algae inhibitor
These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 1 kg. Product ID: 0666186536223. MPN: DBPMFTAB2025-1X1kg. Brand: Deep Blue Pro. Categories: Pool Chemicals.
Lincolnshire, Wiltshire, Online
Deep Blue Pro - Multifunctional Mini 20g Chlorine Tablets 2kg Long lasting stabilised clarifier algae inhibitor
These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 2 kg. Product ID: 0666186536254. MPN: DBPMFTAB2025-1X2kg. Brand: Deep Blue Pro. Categories: Pool Chemicals.
Lincolnshire, Wiltshire, Online
Deep Blue Pro - Multifunctional Mini 20g Chlorine Tablets 3kg Long lasting stabilised clarifier algae inhibitor
These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 3 kg. Product ID: 0666186536261. MPN: DBPMFTAB2025-1X3kg. Brand: Deep Blue Pro. Categories: Pool Chemicals.
Lincolnshire, Wiltshire, Online
Deep Blue Pro - Multifunctional Mini 20g hot tub Chlorine Tablets 2.5kg spa hottub Long lasting stabilised clarifier algae inhibitor
These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 2.5 kg. Product ID: 0666186536230. MPN: DBPMFTAB2025-1X2.5kg. Brand: Deep Blue Pro. Categories: Pool Chemicals.
Lincolnshire, Wiltshire, Online
Deep Blue Pro - Multifunctional Mini 20g hot tub Chlorine Tablets 25kg spa hottub Long lasting stabilised clarifier algae inhibitor
These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 25 kg. Product ID: 0666186535684. MPN: DBPMFTAB2025-1X25kg. Brand: Deep Blue Pro. Categories: Pool Chemicals.
Lincolnshire, Wiltshire, Online
Deep Blue Pro - Multifunctional Mini 20g hot tub Chlorine Tablets 5kg spa hottub Long lasting stabilised clarifier algae inhibitor
These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 5 kg. Product ID: 0666186535691. MPN: DBPMFTAB2025-1X5kg. Brand: Deep Blue Pro. Categories: Pool Chemicals.
Lincolnshire, Wiltshire, Online
Deep Blue Pro - Multifunctional Mini 20g Hot tub Chlorine Tablets x1000 20kg spa hottub Long lasting stabilised clarifier algae inhibitor
These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. These will be sent in multiples of smaller tubs, from 1Kg to 10Kg tubs. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 20 kg. Product ID: 0666186536247. MPN: DBPMFTAB2025-1X20kg. Brand: Deep Blue Pro. Categories: Pool Chemicals.
Lincolnshire, Wiltshire, Online
Deep Blue Pro - Multifunctional Mini hot tub 20g Chlorine Tablets 10kg spa hottub Long lasting stabilised clarifier algae inhibitor
These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 10 kg. Product ID: 0666186536216. MPN: DBPMFTAB2025-1X10kg. Brand: Deep Blue Pro. Categories: Pool Chemicals.
Lincolnshire, Wiltshire, Online
Ehp-inhibitor-1
Ehp-inhibitor-1 is an Eph family tyrosine kinase inhibitor targeting Eph receptors. Study indicated that inhibition of Eph receptors results in an increase in glucose-stimulated insulin secretion from mouse and human pancreatic islets. Group: Pharmaceutical. CAS No. 861249-59-4. Pack Sizes: 50 mg. Product ID: B0084-284759. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ehp-inhibitor-2
Ehp-inhibitor-2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors. Study indicated that inhibition of Eph receptors results in an increase in glucose-stimulated insulin secretion from mouse and human pancreatic islets. Group: Pharmaceutical. CAS No. 861249-77-6. Pack Sizes: 50 mg. Product ID: B0084-284760. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
γ-Secretase Inhibitor I
An inhibitor of gamma-secretase. Group: Pharmaceutical. CAS No. 133407-83-7. Pack Sizes: 100 mg. Product ID: B1370-014023. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
hsa-miR-146a-5p Inhibitor
hsa-miR-146a-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. hsa-miR-146a-5p inhibitors have full-length nucleotide 2'-methoxy modification. They strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Group: Pharmaceutical. Pack Sizes: 5 nmol. Product ID: B1370-449809. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
IRAK-1-4 Inhibitor I
IRAK-1-4 Inhibitor I is a novel benzimidazole that is a potent inhibitor of interleukin-1 receptor-associated kinases 1-4 (IRAK 1-4). Group: Pharmaceutical. CAS No. 509093-47-4. Pack Sizes: 25 mg. Product ID: B2693-302024. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Kallikrein Inhibitor
Kallikrein Inhibitor, a synthetic peptide, is a serine protease inhibitor that inhibits kallikrein and plasmin, and can attenuate breast cancer cell invasion. Group: Pharmaceutical. CAS No. 97145-43-2. Pack Sizes: 10 mg. Product ID: BAT-006188. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
KDM5-inhibitor
KDM5-inhibitor is an analog of CPI-455, a selective KDM5 inhibitor. CPI-455 increases levels of H3K4 trimethylation (H3K4me3) and decreases the number of DTPs in multiple cancer cell lines treated with standard chemotherapy or targeted agents. It reduces survival of drug-tolerant cancer cells. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B0084-284866. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
LKB1/AAK1 dual inhibitor
LKB1/AAK1 dual inhibitor is an effective inhibitor against multi-kinase especially Pim-1 kinase, which has been newly found to be highly expressed in sorts of isolated human cancer cells. Kd: 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1. Group: Pharmaceutical. CAS No. 1093222-27-5. Pack Sizes: 50 mg. Product ID: B2693-456919. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Mutant EGFR inhibitor
Mutant EGFR inhibitor is a potent and selective mutant EGFR inhibitor extracted from patent WO 2013014448 A1. It inhibits EGFRL858R, EGFRExon 19 deletionand EGFRT790M. Group: Pharmaceutical. CAS No. 1421373-62-7. Pack Sizes: 5 mg. Product ID: B0084-463231. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
NFAT Inhibitor
A selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Group: Pharmaceutical. CAS No. 249537-73-3. Pack Sizes: 5 mg. Product ID: BAT-006191. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
PKC-Theta Inhibitor
PKC-theta inhibitor is a selective PKC-theta inhibitor with IC50 of 12 nM. Group: Pharmaceutical. CAS No. 736048-65-0. Pack Sizes: 5 mg. Product ID: B2693-373030. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Protein Kinase Inhibitors 1
Protein Kinase Inhibitors 1 is a HIPK2 inhibitor with IC50 of 74 nM and Kd of 9.5 nM. Group: Pharmaceutical. CAS No. 1365986-44-2. Pack Sizes: 20 mg. Product ID: B0084-284772. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Smad3 Inhibitor, SIS3
Smad3 Inhibitor, SIS 3 is an inhibitor of SMAD3, which is a receptor-regulated intracellular protein that functions downstream of TGF-β as well as activin receptors and mediates their signaling. It plays an important role in cell proliferation, apoptosis, differentiation and formation of extracellular matrix. It is a cell-permeable pyrrolopyridine compound that selectively inhibits TGF-β1-dependent Smad3 phosphorylation and Smad3-mediated cellular signaling. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts. Group: Pharmaceutical. CAS No. 1009104-85-1. Pack Sizes: 25 mg. Product ID: B0084-310534. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
T.cruzi Inhibitor
T.cruzi Inhibitor is a novel inhibitor of Trypanosoma cruzi. Group: Pharmaceutical. CAS No. 1350920-22-7. Pack Sizes: 25 mg. Product ID: B0084-284804. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Trypsin Inhibitor (soybean)
Trypsin Inhibitor (soybean) is a peptide inhibitor of serine proteases that reduces trypsin, as well as plasma kallikrein, thrombin, plasmin, and other serine proteases. Group: Pharmaceutical. CAS No. 9035-81-8. Pack Sizes: 10 g. Product ID: B2693-194378. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Wnt Inhibitor IWP-2
IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM. Uses: Differentiation. Group: Pharmaceutical. CAS No. 686770-61-6. Pack Sizes: 50 mg. Product ID: B0084-272158. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
YAP-TEAD Inhibitor 1
YAP-TEAD Inhibitor 1 is a potent inhibitor of YAP-TEAD interaction with IC50 value of 25 nM. Group: Pharmaceutical. CAS No. 1659305-78-8. Pack Sizes: 2.5 mg. Product ID: BAT-006146. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
(±)-10-Hydroxycamptothecin
(±)-10-Hydroxycamptothecin is an alkaloid derived from the seed or root bark of the deciduous plant Camptotheca acuminata. It has selective inhibitory effect on the phosphorylation of histone H1 and H3, but less effect on other histones. It exhibits anticancer and antiangiogenic activities. It can be used in cosmetics material. Group: Pharmaceutical. CAS No. 64439-81-2. Pack Sizes: 1 g. Product ID: B2703-051417. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
Donepezil impurity. Uses: 4-[(2,3-dihydro-5,6-dimethoxy-1-oxo-1h-inden-2-yl)methyl]-1,1-bis(phenylmethyl)piperidinium is an isotope labelled impurity in the synthesis of donepezil (d531750), an inhibitor of acetylcholinesterase. Group: Pharmaceutical. CAS No. 844694-85-5. Pack Sizes: 100 mg. Product ID: B0794-470368. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor in the class of oral antidiabetic drugs. Group: Pharmaceutical. CAS No. 1353254-15-5. Pack Sizes: 100 mg. Product ID: B1370-425896. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
11-oxo-mogroside V
11-oxo-mogroside V is extracted from the fruits of Siraitia grosvenorii Swingle. It exhibited a remarkable inhibitory effect on *OH-induced DNA damage. Group: Pharmaceutical. CAS No. 126105-11-1. Pack Sizes: 20 mg. Product ID: B0005-465746. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
1,4-Bis(4-nitrophenyl)piperazine
An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Group: Pharmaceutical. CAS No. 16264-05-4. Pack Sizes: 100 mg. Product ID: B1476-166965. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
1-(4-chlorophenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide is an impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Group: Pharmaceutical. CAS No. 2029205-64-7. Pack Sizes: 5 mg. Product ID: B1370-377545. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
1,4-Dihydro-1-(5-methoxy-1H-benzimidazol-2-yl)-3,5-dimethyl-4-oxo-2-pyridinecarboxylic Acid Ammonium Salt
1,4-Dihydro-1-(5-methoxy-1H-benzimidazol-2-yl)-3,5-dimethyl-4-oxo-2-pyridinecarboxylic Acid Ammonium Salt is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Group: Pharmaceutical. CAS No. 2227107-89-1. Pack Sizes: 5 mg. Product ID: B2694-352395. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
1,4 Napthoquinone
1,4 Napthoquinone, CAS 130-15-4, Coatings Inhibitors, Inhibitors and Accelerators. Formerly Lansdowne Chemicals
1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy)phos-phino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]uracil, a potent agent for the treatment of human immunodeficiency virus (HIV) infections, functions as a viral replication inhibitor by suppressing the reverse transcriptase enzyme. Its intricate molecular structure reflects the sophisticated nature of modern pharmaceuticals, which require cutting-edge research and development to ultimately undo the feats of viruses and other elusive adversaries. Group: Pharmaceutical. CAS No. 2361324-80-1. Pack Sizes: 100 mg. Product ID: B2706-341886. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
16-Dehydropregnenolone acetate
16-Dehydropregnenolone acetate is an impurity of Abiraterone, which is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. CAS No. 979-02-2. Pack Sizes: 25 g. Product ID: NP6241. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
16-Hydroxycleroda-3,13-dien-15,16-olide
16-Hydroxycleroda-3,13-dien-15,16-olide is extracted from the unripe fruits of Polyalthia longifolia var. pendula. It is used as a candidate for autophagy inducers which can cause cell death in an alternative or supplement medicine for cancer therapy. It displays promising NO inhibitory activity at 10 ug/mL and shows anti-inflammatory activity. It induces apoptosis in CML K562 cells and regulates the expression of histone-modifying enzymes PRC2 complex. Group: Pharmaceutical. CAS No. 141979-19-3. Pack Sizes: 1 mg. Product ID: NP1411. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
Picraline is a natural alkaloid found in the herbs of Rauvolfia verticillata. Picraline shows potent SGLT inhibitory activity. Group: Pharmaceutical. CAS No. 2671-32-1. Pack Sizes: 1 mg. Product ID: NP0482. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
1-Bromo-4-nitrobenzene-[d4]
1-Bromo-4-nitrobenzene-[d4] - a deuterated analogue of 1-Bromo-4-nitrobenzene, a prominent organic compound studied for its CYP1A2 metabolism inhibitory potential in medicinal science. Its ubiquitous usage in pharmacokinetic studies of 1-Bromo-4-nitrobenzene-integrated drugs implicates its significance. It serves as an ideal candidate for studying the influence of deuterium substitution on drug pharmacokinetics and metabolism. Group: Pharmaceutical. CAS No. 350820-19-8. Pack Sizes: 25 mg. Product ID: BLP-010238. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
1-epi-Edoxaban
An impurity of Edoxaban, an oral anticoagulant drug and a direct factor Xa inhibitor. Group: Pharmaceutical. CAS No. 500572-10-1. Pack Sizes: 1 mg. Product ID: B2694-338760. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
1-Ethyl-2-methylpyridinium bromide
1-Ethyl-2-methylpyridinium bromide is a reagent used in the preparation and studies of MKT-077, which is an inhibitor of heat shock protein 70 as an anticancer agent. Group: Pharmaceutical. CAS No. 32353-50-7. Pack Sizes: 25 g. Product ID: BB077788. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
1-NA-PP1
1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. Group: Pharmaceutical. CAS No. 221243-82-9. Pack Sizes: 25 mg. Product ID: B2693-102805. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
((1R,3R)-3-Amino-cyclopentyl)-carbamic Acid tert-Butyl Ester is used in the preparation of quinoline-3-carboxoamides as H-PGDS inhibitors as well as novel triazolo-pyrrolopyridines as Janus kinase 1 inhibitors. Group: Pharmaceutical. CAS No. 1009075-44-8. Pack Sizes: 1 g. Product ID: BB074488. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
(1R, 3R, 4R)- Entecavir
An isomer of Entecavir. Entecavir is a reverse transcriptase inhibitor. It prevents the hepatitis B virus from multiplying and reduces the amount of virus in the body. Group: Pharmaceutical. CAS No. 1367369-76-3. Pack Sizes: 1 mg. Product ID: B0249-471009. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
(1R, 3S, 4R)-ent-Entecavir
An isomer of Entecavir. Entecavir is a reverse transcriptase inhibitor. It prevents the hepatitis B virus from multiplying and reduces the amount of virus in the body. Group: Pharmaceutical. CAS No. 188399-46-4. Pack Sizes: 5 mg. Product ID: B0249-471013. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
1R-Dapagliflozin
1R-Dapagliflozin is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Group: Pharmaceutical. CAS No. 1373321-04-0. Pack Sizes: 1 mg. Product ID: B2694-352557. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
(1S,3R)-RSL3
(1S,3R)-RSL3 is a glutathione peroxidase 4 (GPX4) inhibitor with EC50 of 10 μM in cellular assay. It binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis. Group: Pharmaceutical. CAS No. 1219810-16-8. Pack Sizes: 100 mg. Product ID: B0084-474402. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
21-Episerratenediol
21-Episerratenediol is a natural triterpenoid found in the herbs of Lycopodium serratum, it exhibited a remarkable inhibitory effect on skin tumor promotion in an in vivo two-stage mouse skin carcinogenesis test using 7,12-dimethylbenz[a]anthracene as an initiator and TPA as a promoter which indicates that 21-episerratenediol might has the activity of anti-cancer. Uses: Anti-cancer; anti-tumor. Group: Pharmaceutical. CAS No. 1449-06-5. Pack Sizes: 1 mg. Product ID: NP6511. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
2,3,4,6-Tetra-O-acetyl-a-D-mannopyranose
2,3,4,6-Tetra-O-acetyl-a-D-mannopyranose is a key intermediary in the biomedical industry used in the synthesis of antiviral drugs. It contributes to the research and development of potent inhibitors for diseases such as HIV and influenza. Group: Pharmaceutical. CAS No. 22860-22-6. Pack Sizes: 5 g. Product ID: B1370-225349. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor in the class of oral antidiabetic drugs. Group: Pharmaceutical. CAS No. 2089611-85-6. Pack Sizes: 100 mg. Product ID: B1370-425895. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Group: Pharmaceutical. CAS No. 885126-34-1. Pack Sizes: 100 mg. Product ID: B2694-467100. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Group: Pharmaceutical. CAS No. 171273-35-1. Pack Sizes: 100 mg. Product ID: B0464-284943. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Group: Pharmaceutical. CAS No. 154127-41-0. Pack Sizes: 100 mg. Product ID: NP3243. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
2,3-trimethylene-4-quinazolone
Deoxyvasicinone can be found in the herbs of Galium aparine L. The Deoxyvasicinone derivatives could be considered as promising lead molecules for the development of more potent inhibitors of NEDD8-activating enzyme. Group: Pharmaceutical. CAS No. 530-53-0. Pack Sizes: 1 mg. Product ID: NP0366. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
2,4,6-trichloro-N-phenylaniline
A Diclofenac impurity which is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively. Group: Pharmaceutical. CAS No. 15362-44-4. Pack Sizes: 10 mg. Product ID: B1370-379610. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
2,5-Dioxopyrrolidin-1-yl 3-(tritylthio)propanoate
2,5-Dioxopyrrolidin-1-yl 3-(tritylthio)propanoate, a multifaceted chemical compound, plays a pivotal role in drug synthesis, specifically in the development of angiotensin converting enzyme inhibitors. In addition to its significance in this domain, it functions as a valuable building block in drug development for maladies such as hypertension, heart failure, and diabetes. Its diverse utilization and multifarious potential thereby make it a crucial focus of drug research. Group: Pharmaceutical. CAS No. 129431-12-5. Pack Sizes: 1 g. Product ID: B0001-286444. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
2,5 Di- Tertiary- Butylhydroquinone
2,5 Di- Tertiary- Butylhydroquinone, CAS 88-58-4, Coatings Inhibitors, Inhibitors and Accelerators. Formerly Lansdowne Chemicals
25-hydroxycholesterol is an inhibitor of human immunodeficiency virus replication in vitro. It induces apoptosis in human monocytic cell lines as well as in CEM cells associated with negative regulation of c-Myc. Group: Pharmaceutical. CAS No. 2140-46-7. Pack Sizes: 200 mg. Product ID: B2693-000027. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
2,9-Dibromo-1,10-Phenanthroline
2,9-Dibromo-1,10-Phenanthroline, a heterocyclic aromatic compound comprising two fused six-membered rings, is an indispensable element in the field of biomedical research due to its unique properties. With its proficient nature, this compound provides a remarkable breakthrough in detecting and quantifying a wide range of metal ions. Its chelating activity along with its potential inhibitory effect towards metal-dependent enzymes makes it a valuable tool for a diverse range of laboratory applications. Further, with its exceptional medicinal properties, it plays a pivotal role in developing drugs to combat complex and multifactorial diseases such as cancer and Alzheimer's, highlighting the remarkable impact of this compound in the biomedical field. Group: Pharmaceutical. CAS No. 39069-02-8. Pack Sizes: 5 g. Product ID: B2699-179946. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
2-Amino-2'-fluorobenzophenone
An intermediate in the synthesis of Pitavastatin, a HMG-CoA reductase inhibitor that lowers LDL cholesterol and triglycerides and increase HDL cholesterol in your blood. Group: Pharmaceutical. CAS No. 1581-13-1. Pack Sizes: 1 g. Product ID: B2694-010195. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
2-Aminoethylphosphonic acid
2-Aminoethylphosphonic acid is a biogenic substance and an endogenous metabolite. It also acts as a reagent in the synthesis of phosphonoxins, a new class of anti-microbial agent that also functions as an inhibitor of Giardia trophozoite growth. Group: Pharmaceutical. CAS No. 2041-14-7. Pack Sizes: 5 g. Product ID: B1370-308145. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
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