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| Product | Description | |
|---|---|---|
| ALK5 Inhibitor II hydrochloride | ALK5 inhibitor II was identified as a cell permeable, selective inhibitor of the TGF-β type 1 activin like kinase receptor ALK5 (ALK5 autophosphorylation, IC50s = 4 nM, TGF-β cellular assay, IC50s = 18 nM, ALK5 binding in HepG2 cells, IC50s = 23 nM). This compound has been used to induce stem cell pluripotency by replacing the reprogramming transcription factor Sox2 via inhibition of the TGF-β signaling pathway and induction of Nanog transcription. This product is a hydrochloride form. Group: Pharmaceutical. Alternative Names: E 616452; RepSox; SJN 2511. CAS No. 446859-33-2. Pack Sizes: 50 mg. Product ID: B0084-068993. Molecular formula: C17H13N5·HCl. Mole weight: 323.8. Custom synthesis is available. Send your inquiries for more information. |  London |
| Cathepsin S inhibitor | Cathepsin S is expressed in antigen-presenting cells and plays a role in invariant chain processing and major histocompatibility complex class II (MHCII) antigen presentation leading to CD4+ T-cell activation. An oral Cathepsin S inhibitor that blocks MHCII antigen presentation could result in a T-cell-selective immunosuppressant agent with improved safety over the current standard of care for the treatment of rheumatoid arthritis, psoriasis, multiple sclerosis and other autoimmune-based inflammatory diseases. Group: Pharmaceutical. Alternative Names: LY3000328; LY-3000328; LY 3000328. Cathepsin S inhibitor. CAS No. 1373215-15-6. Pack Sizes: 10 mg. Product ID: B0084-463202. Molecular formula: C25H29FN4O5. Mole weight: 484.52. Custom synthesis is available. Send your inquiries for more information. | London |
| Corrosion Inhibitor | Newport have an equivalent to market leading speciality corrosion inhibitors. After more than 5 years in development and production trials, we are commercially marketing this product to specific clients. |  England, Surrey |
| CTLA-4 inhibitor | CTLA-4 inhibitor is an inhibitor of CTLA-4, an immune checkpoint negatively regulating T cell function. CTLA-4 is thought to regulate T-cell proliferation early in an immune response, primarily in lymph nodes. Group: Pharmaceutical. Alternative Names: MDK24720; MDK 24720; MDK-24720; CTLA-4 inhibitor. 2-(4-Fluorophenyl)-6-methyl-4-(3-(trifluoromethyl)phenyl)-1,2-dihydrodipyrazolo[3,4-b:3',4'-d]pyridin-3(6H)-one; EX-A913. CAS No. 635324-72-0. Pack Sizes: 10 mg. Product ID: B0084-284810. Molecular formula: C21H13F4N5O. Mole weight: 427.363. Custom synthesis is available. Send your inquiries for more information. | London |
| Deep Blue Pro - Multifunctional 200g Chlorine Tablets 10 kg Long lasting stabilised clarifier algae inhibitor | These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; chlorine tablets. Grades: A+. Pack Size: 10 kg. Product ID: 0666186536179. MPN: DBPMFTAB2005-1X10kg. Brand: Deep Blue Pro. Categories: Pool Chemicals. |  Lincolnshire, Wiltshire, Online |
| Deep Blue Pro - Multifunctional 200g Chlorine Tablets 1 kg Long lasting stabilised clarifier algae inhibitor | These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; chlorine tablets. Grades: A+. Pack Size: 1 kg. Product ID: 0666186536186. MPN: DBPMFTAB2005-1X1kg. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro - Multifunctional 200g Chlorine Tablets 25 kg Long lasting stabilised clarifier algae inhibitor | These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; chlorine tablets. Grades: A+. Pack Size: 25 kg. Product ID: 0666186535660. MPN: DBPMFTAB2005-1X25kg. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro - Multifunctional 200g Chlorine Tablets 2 kg Long lasting stabilised clarifier algae inhibitor | These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; chlorine tablets. Grades: A+. Pack Size: 2 kg. Product ID: 0666186536209. MPN: DBPMFTAB2005-1X2kg. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro - Multifunctional 200g Chlorine Tablets 5 kg Long lasting stabilised clarifier algae inhibitor | These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; chlorine tablets. Grades: A+. Pack Size: 5 kg. Product ID: 0666186535677. MPN: DBPMFTAB2005-1X5kg. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro - Multifunctional 200g Chlorine Tablets x100 20kg Long lasting stabilised clarifier algae inhibitor | These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. These will be sent in multiples of smaller tubs, from 1Kg to 10Kg tubs. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; chlorine tablets. Grades: A+. Pack Size: 20 kg. Product ID: 0666186536193. MPN: DBPMFTAB2005-1X20kg. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro - Multifunctional Mini 20g Chlorine Tablets 1kg Long lasting stabilised clarifier algae inhibitor | These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 1 kg. Product ID: 0666186536223. MPN: DBPMFTAB2025-1X1kg. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro - Multifunctional Mini 20g Chlorine Tablets 2kg Long lasting stabilised clarifier algae inhibitor | These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 2 kg. Product ID: 0666186536254. MPN: DBPMFTAB2025-1X2kg. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro - Multifunctional Mini 20g Chlorine Tablets 3kg Long lasting stabilised clarifier algae inhibitor | These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 3 kg. Product ID: 0666186536261. MPN: DBPMFTAB2025-1X3kg. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro - Multifunctional Mini 20g hot tub Chlorine Tablets 2.5kg spa hottub Long lasting stabilised clarifier algae inhibitor | These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 2.5 kg. Product ID: 0666186536230. MPN: DBPMFTAB2025-1X2.5kg. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro - Multifunctional Mini 20g hot tub Chlorine Tablets 25kg spa hottub Long lasting stabilised clarifier algae inhibitor | These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 25 kg. Product ID: 0666186535684. MPN: DBPMFTAB2025-1X25kg. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro - Multifunctional Mini 20g hot tub Chlorine Tablets 5kg spa hottub Long lasting stabilised clarifier algae inhibitor | These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 5 kg. Product ID: 0666186535691. MPN: DBPMFTAB2025-1X5kg. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro - Multifunctional Mini 20g Hot tub Chlorine Tablets x1000 20kg spa hottub Long lasting stabilised clarifier algae inhibitor | These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. These will be sent in multiples of smaller tubs, from 1Kg to 10Kg tubs. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 20 kg. Product ID: 0666186536247. MPN: DBPMFTAB2025-1X20kg. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro - Multifunctional Mini hot tub 20g Chlorine Tablets 10kg spa hottub Long lasting stabilised clarifier algae inhibitor | These multifunctional chlorine tablets are an enhanced tablet containing stabilised chlorine, a clarifier and an algaecide. This is a great solution for keeping your pool or hot tub sparkling clear without the need for separate care products. They are great for ensuring hot tub and swimming pool water is safe and bacteria free. The stabiliser helps minimise chlorine loss to sunlight. The clarifier will keep your water clear and prevent it going cloudy. The algaecide helps prevent algae growth and stops your pool going green. With these ingredients combined these multifunctional tablets help provide the best experience for bathers with minimal maintenance effort. They are slow release and will last around 3 4 days depending on the water flowing over them. They can be used in floating dispensers, chemical feeds and skimmer baskets. Apply regularly to achieve the recommended free chlorine level of 3-5 mg/l (ppm) for hot tubs or 1-3 mg/l (ppm) for swimming pools. These tablets are slow r . Uses: Swimming pools, hot tubs. Chlorine best for pools; chlorine best for tubs; hot tub chlorine tablets. Grades: A+. Pack Size: 10 kg. Product ID: 0666186536216. MPN: DBPMFTAB2025-1X10kg. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Ehp-inhibitor-1 | Ehp-inhibitor-1 is an Eph family tyrosine kinase inhibitor targeting Eph receptors. Study indicated that inhibition of Eph receptors results in an increase in glucose-stimulated insulin secretion from mouse and human pancreatic islets. Group: Pharmaceutical. Alternative Names: 6-(3-methoxyphenyl)-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine. CAS No. 861249-59-4. Pack Sizes: 50 mg. Product ID: B0084-284759. Molecular formula: C18H15N5O. Mole weight: 317.352. Custom synthesis is available. Send your inquiries for more information. | London |
| Ehp-inhibitor-2 | Ehp-inhibitor-2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors. Study indicated that inhibition of Eph receptors results in an increase in glucose-stimulated insulin secretion from mouse and human pancreatic islets. Group: Pharmaceutical. Alternative Names: 3-(7-amino-3-(pyridin-3-yl)pyrazolo[1,5-a]pyrimidin-6-yl)phenol. CAS No. 861249-77-6. Pack Sizes: 50 mg. Product ID: B0084-284760. Molecular formula: C17H13N5O. Mole weight: 303.325. Custom synthesis is available. Send your inquiries for more information. | London |
| γ-Secretase Inhibitor I | An inhibitor of gamma-secretase. Group: Pharmaceutical. Alternative Names: Cbz-leucinyl-leucinyl-norleucinal; Z-Leu-Leu-Nle-CHO; gamma-Secretase Inhibitor I; N-benzoxycarbonyl-L-leucyl-L-leucyl-L-norleucinal. CAS No. 133407-83-7. Pack Sizes: 100 mg. Product ID: B1370-014023. Molecular formula: C26H41N3O5. Mole weight: 475.62. Custom synthesis is available. Send your inquiries for more information. | London |
| hsa-miR-146a-5p Inhibitor | hsa-miR-146a-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. hsa-miR-146a-5p inhibitors have full-length nucleotide 2'-methoxy modification. They strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Group: Pharmaceutical. Pack Sizes: 5 nmol. Product ID: B1370-449809. Mole weight: 6592.37. Custom synthesis is available. Send your inquiries for more information. | London |
| IRAK-1-4 Inhibitor I | IRAK-1-4 Inhibitor I is a novel benzimidazole that is a potent inhibitor of interleukin-1 receptor-associated kinases 1-4 (IRAK 1-4). Group: Pharmaceutical. Alternative Names: Benzamide, N-[1-[2-(4-morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitro-. CAS No. 509093-47-4. Pack Sizes: 25 mg. Product ID: B2693-302024. Molecular formula: C20H21N5O4. Mole weight: 395.41. Custom synthesis is available. Send your inquiries for more information. | London |
| Kallikrein Inhibitor | Kallikrein Inhibitor, a synthetic peptide, is a serine protease inhibitor that inhibits kallikrein and plasmin, and can attenuate breast cancer cell invasion. Group: Pharmaceutical. Alternative Names: KKI 5; KKI-5; KKI5; Ac-Pro-phe-arg-ser-val-gln-NH2; (S)-2-((3S,6S,9S,12S)-1-((S)-1-acetylpyrrolidin-2-yl)-3-benzyl-6-(3-guanidinopropyl)-9-(hydroxymethyl)-12-isopropyl-1,4,7,10-tetraoxo-2,5,8,11-tetraazatridecan-13-amido)pentanediamide; N-acetyl-L-prolyl-L-phenylalanyl-L-arginyl-L-seryl-L-valyl-L-glutaminamide. CAS No. 97145-43-2. Pack Sizes: 10 mg. Product ID: BAT-006188. Molecular formula: C35H55N11O9. Mole weight: 773.88. Custom synthesis is available. Send your inquiries for more information. | London |
| KDM5-inhibitor | KDM5-inhibitor is an analog of CPI-455, a selective KDM5 inhibitor. CPI-455 increases levels of H3K4 trimethylation (H3K4me3) and decreases the number of DTPs in multiple cancer cell lines treated with standard chemotherapy or targeted agents. It reduces survival of drug-tolerant cancer cells. Group: Pharmaceutical. Alternative Names: KDM5 inhibitor; 7-oxo-5-phenyl-6-propyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile. Pack Sizes: 10 mg. Product ID: B0084-284866. Molecular formula: C16H14N4O. Mole weight: 278.315. Custom synthesis is available. Send your inquiries for more information. | London |
| LKB1/AAK1 dual inhibitor | LKB1/AAK1 dual inhibitor is an effective inhibitor against multi-kinase especially Pim-1 kinase, which has been newly found to be highly expressed in sorts of isolated human cancer cells. Kd: 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1. Group: Pharmaceutical. Alternative Names: LKB1/AAK1 dual inhibitor; MDK-2275; MDK 2275; MDK2275; Pim1/AKK1-IN-1; N-[5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-3-pyridinecarboxamide; Pim1 AKK1-IN-1. CAS No. 1093222-27-5. Pack Sizes: 50 mg. Product ID: B2693-456919. Molecular formula: C20H13N5O. Mole weight: 339.35. Custom synthesis is available. Send your inquiries for more information. | London |
| MMP-2/MMP-9 Inhibitor I | MMP-2/MMP-9 inhibitor I is a potent inhibitor of matrix metalloproteinase MMP-2/MMP-9 with IC50 values of 310 and 240 nM, respectively. It blocks MMP-2/MMP-9-dependent invasion, tumor growth, and metastasis in both cell culture and mouse tumor models. Group: Pharmaceutical. Alternative Names: Gelatinase A; N-([1,1'-biphenyl]-4-ylsulfonyl)-D-phenylalanine. CAS No. 193807-58-8. Pack Sizes: 100 mg. Product ID: B1370-291169. Molecular formula: C21H19NO4S. Mole weight: 381.44. Custom synthesis is available. Send your inquiries for more information. | London |
| Mutant EGFR inhibitor | Mutant EGFR inhibitor is a potent and selective mutant EGFR inhibitor extracted from patent WO 2013014448 A1. It inhibits EGFRL858R, EGFRExon 19 deletionand EGFRT790M. Group: Pharmaceutical. Alternative Names: MDK3627; MDK 3627; MDK-3627; Mutant EGFR inhibitor. CAS No. 1421373-62-7. Pack Sizes: 5 mg. Product ID: B0084-463231. Molecular formula: C27H30ClN7O2. Mole weight: 520.03. Custom synthesis is available. Send your inquiries for more information. | London |
| NFAT Inhibitor | A selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Group: Pharmaceutical. Alternative Names: H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-OH; L-methionyl-L-alanyl-glycyl-L-prolyl-L-histidyl-L-prolyl-L-valyl-L-isoleucyl-L-valyl-L-isoleucyl-L-threonyl-glycyl-L-prolyl-L-histidyl-L-alpha-glutamyl-L-glutamic acid. CAS No. 249537-73-3. Pack Sizes: 5 mg. Product ID: BAT-006191. Molecular formula: C75H118N20O22S. Mole weight: 1683.93. Custom synthesis is available. Send your inquiries for more information. | London |
| PKC-Theta Inhibitor | PKC-theta inhibitor is a selective PKC-theta inhibitor with IC50 of 12 nM. Group: Pharmaceutical. Alternative Names: CHEMBL248183; N4-((4-(Aminomethyl)Cyclohexyl)Methyl)-5-Nitro-N2-(2-(Trifluoromethoxy)Benzyl)Pyrimidine-2,4-Diamine; VC-8650; SCHEMBL3953579. CAS No. 736048-65-0. Pack Sizes: 5 mg. Product ID: B2693-373030. Molecular formula: C20H25F3N6O3. Mole weight: 454.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Protein Kinase Inhibitors 1 | Protein Kinase Inhibitors 1 is a HIPK2 inhibitor with IC50 of 74 nM and Kd of 9.5 nM. Group: Pharmaceutical. Alternative Names: 2,4-Thiazolidinedione, 5-[[1,2-dihydro-2-oxo-6'-(1-piperazinyl)[3,3'-bipyridin]-5-yl]methylene]-; 5-((2-oxo-6'-(piperazin-1-yl)-1,2-dihydro-[3,3'-bipyridin]-5-yl)methylene)thiazolidine-2,4-dione; 5-[[1,2-Dihydro-2-oxo-6'-(1-piperazinyl)[3,3'-bipyridin]-5-yl]methylene]-2,4-thiazolidinedione. CAS No. 1365986-44-2. Pack Sizes: 20 mg. Product ID: B0084-284772. Molecular formula: C18H17N5O3S. Mole weight: 383.43. Custom synthesis is available. Send your inquiries for more information. | London |
| Smad3 Inhibitor, SIS3 | Smad3 Inhibitor, SIS 3 is an inhibitor of SMAD3, which is a receptor-regulated intracellular protein that functions downstream of TGF-β as well as activin receptors and mediates their signaling. It plays an important role in cell proliferation, apoptosis, differentiation and formation of extracellular matrix. It is a cell-permeable pyrrolopyridine compound that selectively inhibits TGF-β1-dependent Smad3 phosphorylation and Smad3-mediated cellular signaling. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts. Group: Pharmaceutical. Alternative Names: 1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one. CAS No. 1009104-85-1. Pack Sizes: 25 mg. Product ID: B0084-310534. Molecular formula: C28H27N3O3. Mole weight: 453.542. Custom synthesis is available. Send your inquiries for more information. | London |
| T.cruzi Inhibitor | T.cruzi Inhibitor is a novel inhibitor of Trypanosoma cruzi. Group: Pharmaceutical. Alternative Names: N-Benzyl-N-methyl-1-(4-(trifluoromethyl)benzyl)piperidine-3-carboxamide. CAS No. 1350920-22-7. Pack Sizes: 25 mg. Product ID: B0084-284804. Molecular formula: C22H25F3N2O. Mole weight: 390.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Trypsin Inhibitor (soybean) | Trypsin Inhibitor (soybean) is a peptide inhibitor of serine proteases that reduces trypsin, as well as plasma kallikrein, thrombin, plasmin, and other serine proteases. Group: Pharmaceutical. Alternative Names: Kunitz Trypsin Inhibitor; MR 20; SBTI. CAS No. 9035-81-8. Pack Sizes: 10 g. Product ID: B2693-194378. Custom synthesis is available. Send your inquiries for more information. | London |
| Wnt Inhibitor IWP-2 | IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM. Uses: Differentiation. Group: Pharmaceutical. Alternative Names: IWP 2, IWP-2, IWP2. CAS No. 686770-61-6. Pack Sizes: 50 mg. Product ID: B0084-272158. Molecular formula: C22H18N4O2S3. Mole weight: 466.592. Custom synthesis is available. Send your inquiries for more information. | London |
| YAP-TEAD Inhibitor 1 | YAP-TEAD Inhibitor 1 is a potent inhibitor of YAP-TEAD interaction with IC50 value of 25 nM. Group: Pharmaceutical. Alternative Names: YAP-TEAD-IN-1; YAP-TEAD (Peptide 17). CAS No. 1659305-78-8. Pack Sizes: 2.5 mg. Product ID: BAT-006146. Molecular formula: C93H144ClN23O21S2. Mole weight: 2019.86. Custom synthesis is available. Send your inquiries for more information. | London |
| 10-[(2S)-2-Aminobutanoic acid]cyclosporin A | Cyclosporin Impurity 5 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Group: Pharmaceutical. Alternative Names: Ciclosporin Impurity F; 1,11-Anhydro[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-(2S)-2-aminobutanoyl-N-methyl-L-leucine]; [Abu10]ciclosporin A; Cyclosporin Impurity 5; Cyclosporin A, 10-[(2S)-2-aminobutanoic acid]-; [Abu5]cyclosporin; cyclo[Abu-Sar-N(Me)Leu-Abu-N(Me)Leu-Ala-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)]; cyclo[(N-(((2S)-2-aminobutyryl)-sarcosyl-N-methyl-L-leucyl)-(2S)-2-aminobutyryl)-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-N-methyl-(4R)-4-[(E)-but-2-enyl]-4-methyl-L-threonyl]; (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-21,30-Diethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3-isopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone; Ciclosporin EP Impurity F; [Abu10]cyclosporine A; Cyclosporine Abu-5 Impurity. CAS No. 437611-17-1. Pack Sizes: 1mg;1g;10g. Product ID: BBF-05761. Molecular formula: C61H109N11O12. Mole weight: 1188.58. Custom synthesis is avai | London |
| (±)-10-Hydroxycamptothecin | (±)-10-Hydroxycamptothecin is an alkaloid derived from the seed or root bark of the deciduous plant Camptotheca acuminata. It has selective inhibitory effect on the phosphorylation of histone H1 and H3, but less effect on other histones. It exhibits anticancer and antiangiogenic activities. It can be used in cosmetics material. Group: Pharmaceutical. Alternative Names: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-, (±)-; (+/-)-10-Hydroxycamptothecin; 4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione. CAS No. 64439-81-2. Pack Sizes: 1 g. Product ID: B2703-051417. Molecular formula: C20H16N2O5. Mole weight: 364.35. Custom synthesis is available. Send your inquiries for more information. | London |
| 1,11b-Dedihydrotetrabenazine | 1,11b-Dedihydrotetrabenazine is a product of photolytic degradation of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Group: Pharmaceutical. Alternative Names: Tetrabenazine Dehydro Impurity; 3-Isobutyl-9,10-dimethoxy-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one; 3,4,6,7-Tetrahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one. CAS No. 100322-43-8. Pack Sizes: 100 mg. Product ID: B1370-039615. Molecular formula: C19H25NO3. Mole weight: 315.41. Custom synthesis is available. Send your inquiries for more information. | London |
| 1,1-Dibenzyl-4-[(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl]-1-piperidinium Bromide | Donepezil impurity. Uses: 4-[(2,3-dihydro-5,6-dimethoxy-1-oxo-1h-inden-2-yl)methyl]-1,1-bis(phenylmethyl)piperidinium is an isotope labelled impurity in the synthesis of donepezil (d531750), an inhibitor of acetylcholinesterase. Group: Pharmaceutical. Alternative Names: 2-[[1,1-bis(phenylmethyl)-4-piperidin-1-iumyl]methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;bromide; 2-[(1,1-dibenzylpiperidin-1-ium-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;bromide. CAS No. 844694-85-5. Pack Sizes: 100 mg. Product ID: B0794-470368. Molecular formula: C31H36BrNO3. Mole weight: 550.53. Custom synthesis is available. Send your inquiries for more information. | London |
| 1,1-Dimethylethyl N-[(3R)-1-[(2-cyanophenyl)methyl]-3-piperidinyl]carbamate | An impurity of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor in the class of oral antidiabetic drugs. Group: Pharmaceutical. Alternative Names: Carbamic acid, N-[(3R)-1-[(2-cyanophenyl)methyl]-3-piperidinyl]-, 1,1-dimethylethyl ester. CAS No. 1353254-15-5. Pack Sizes: 100 mg. Product ID: B1370-425896. Molecular formula: C18H25N3O2. Mole weight: 315.41. Custom synthesis is available. Send your inquiries for more information. | London |
| 11-oxo-mogroside V | 11-oxo-mogroside V is extracted from the fruits of Siraitia grosvenorii Swingle. It exhibited a remarkable inhibitory effect on *OH-induced DNA damage. Group: Pharmaceutical. Alternative Names: (24R)-3β-[6-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyloxy]-24-[2-O,6-O-bis(β-D-glucopyranosyl)-β-D-glucopyranosyloxy]-25-hydroxycucurbit-5-en-11-one; 11-Oxomogroside V; (3beta,9beta,10alpha,24R)-24-[(O-beta-D-Glucopyranosyl-(1-2)-O-[beta-D-glucopyranosyl-(1-6)]-beta-D-glucopyranosyl)oxy]-3-[(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-25-hydroxy-9-methyl-19-norlanost-5-en-11-one; 11-O-Mogroside V. CAS No. 126105-11-1. Pack Sizes: 20 mg. Product ID: B0005-465746. Molecular formula: C60H100O29. Mole weight: 1285.4. Custom synthesis is available. Send your inquiries for more information. | London |
| 1-[2-[(2-Methylphenyl)thio]phenyl]piperazine hydrobromide | One of the impurities of Vortioxetine, which is a 5-HT receptor inhibitor as well as a serotonin transporter. Vortioxetine has been found to be an atypical antidepressant. Group: Pharmaceutical. Alternative Names: Vortioxetine Impurity 1 HBr salt; Piperazine, 1-[2-[(2-methylphenyl)thio]phenyl]-, hydrobromide (1:1). CAS No. 1293343-91-5. Pack Sizes: 10 mg. Product ID: B1370-449711. Molecular formula: C17H21BrN2S. Mole weight: 365.33. Custom synthesis is available. Send your inquiries for more information. | London |
| 1-(2-(o-tolylthio)phenyl)piperazine hydrochloride | One of the impurities of Vortioxetine, which is a 5-HT receptor inhibitor as well as a serotonin transporter. Vortioxetine has been found to be an atypical antidepressant. Group: Pharmaceutical. Alternative Names: Vortioxetine Impurity 1 HCl salt; 1-[2-(2-Methylphenylsulfanyl)phenyl]piperazine hydrochloride; Piperazine, 1-[2-[(2-methylphenyl)thio]phenyl]-, hydrochloride (1:1). CAS No. 1293342-91-2. Pack Sizes: 10 mg. Product ID: B1370-099172. Molecular formula: C17H21ClN2S. Mole weight: 320.88. Custom synthesis is available. Send your inquiries for more information. | London |
| 13-O-Desmethyl Tacrolimus | 13-O-Desmethyl Tacrolimus is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Group: Pharmaceutical. Alternative Names: (3S,4R,5S,8R,9E,12S,14S,15S,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26-Hexadecahydro-5,16,19-trihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14-methoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-16,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone. CAS No. 139958-51-3. Pack Sizes: 5 mg. Product ID: B1370-386089. Molecular formula: C43H67NO12. Mole weight: 789.99. Custom synthesis is available. Send your inquiries for more information. | London |
| 1-(4-(5-methyl-2-oxopiperidin-1-yl)phenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one | An impurity of Apixaban, which is a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Group: Pharmaceutical. Alternative Names: Apixaban Impurity 33; 2(1H)-Pyridinone, 5,6-dihydro-1-[4-(5-methyl-2-oxo-1-piperidinyl)phenyl]-3-(4-morpholinyl)-. CAS No. 1686149-78-9. Pack Sizes: 50 mg. Product ID: B1370-455515. Molecular formula: C21H27N3O3. Mole weight: 369.47. Custom synthesis is available. Send your inquiries for more information. | London |
| 1,4-Bis(4-nitrophenyl)piperazine | An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Group: Pharmaceutical. Alternative Names: 1,4-Bis(4-nitrophenyl)piperazine; 16264-05-4; Piperazine, 1,4-bis(4-nitrophenyl)-EINECS 240-371-8UNII-P6TE7B2EYY. CAS No. 16264-05-4. Pack Sizes: 100 mg. Product ID: B1476-166965. Molecular formula: C16H16N4O4. Mole weight: 328.328. Custom synthesis is available. Send your inquiries for more information. | London |
| 1-(4-chlorophenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 1-(4-chlorophenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide is an impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Group: Pharmaceutical. Alternative Names: Apixaban Chloro Impurity; 1-(4-Chlorophenyl)-4,5,6,7-tetrahydro-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide. CAS No. 2029205-64-7. Pack Sizes: 5 mg. Product ID: B1370-377545. Molecular formula: C24H22ClN5O3. Mole weight: 463.92. Custom synthesis is available. Send your inquiries for more information. | London |
| 1,4-Dihydro-1-(5-methoxy-1H-benzimidazol-2-yl)-3,5-dimethyl-4-oxo-2-pyridinecarboxylic Acid Ammonium Salt | 1,4-Dihydro-1-(5-methoxy-1H-benzimidazol-2-yl)-3,5-dimethyl-4-oxo-2-pyridinecarboxylic Acid Ammonium Salt is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Group: Pharmaceutical. Alternative Names: OMP-A Ammonium Salt. CAS No. 2227107-89-1. Pack Sizes: 5 mg. Product ID: B2694-352395. Molecular formula: C16H18N4O4. Mole weight: 330.34. Custom synthesis is available. Send your inquiries for more information. | London |
| 1,4 Napthoquinone | 1,4 Napthoquinone, CAS 130-15-4, Coatings Inhibitors, Inhibitors and Accelerators. Formerly Lansdowne Chemicals | OQEMA England, Oxfordshire |
| 1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy)phos-phino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]uracil | 1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy)phos-phino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]uracil, a potent agent for the treatment of human immunodeficiency virus (HIV) infections, functions as a viral replication inhibitor by suppressing the reverse transcriptase enzyme. Its intricate molecular structure reflects the sophisticated nature of modern pharmaceuticals, which require cutting-edge research and development to ultimately undo the feats of viruses and other elusive adversaries. Group: Pharmaceutical. Alternative Names: 2,4(1H,3H)-Pyrimidinedione, 1-[(5E)-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]-. CAS No. 2361324-80-1. Pack Sizes: 100 mg. Product ID: B2706-341886. Molecular formula: C24H40N4O9P2. Mole weight: 590.54. Custom synthesis is available. Send your inquiries for more information. | London |
| 16-Dehydropregnenolone acetate | 16-Dehydropregnenolone acetate is an impurity of Abiraterone, which is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Group: Pharmaceutical. Alternative Names: Dehydropregnenolone acetate; 16,17-Didehydropregnenolone acetate. CAS No. 979-02-2. Pack Sizes: 25 g. Product ID: NP6241. Molecular formula: C23H32O3. Mole weight: 356.51. Custom synthesis is available. Send your inquiries for more information. | London |
| 16-Hydroxycleroda-3,13-dien-15,16-olide | 16-Hydroxycleroda-3,13-dien-15,16-olide is extracted from the unripe fruits of Polyalthia longifolia var. pendula. It is used as a candidate for autophagy inducers which can cause cell death in an alternative or supplement medicine for cancer therapy. It displays promising NO inhibitory activity at 10 ug/mL and shows anti-inflammatory activity. It induces apoptosis in CML K562 cells and regulates the expression of histone-modifying enzymes PRC2 complex. Group: Pharmaceutical. Alternative Names: 5-Hydroxy-4-[2-[[(1S)-1,2,3,4,4a,7,8,8abeta-octahydro-1alpha,2alpha,4aalpha,5-tetramethylnaphthalen]-1-yl]ethyl]furan-2(5H)-one. CAS No. 141979-19-3. Pack Sizes: 1 mg. Product ID: NP1411. Molecular formula: C20H30O3. Mole weight: 318.45. Custom synthesis is available. Send your inquiries for more information. | London |
| (16R)-17-(Acetoxy)-2α,5α-epoxy-1,2-dihydroakuammilan-16-carboxylic acid methyl ester | Picraline is a natural alkaloid found in the herbs of Rauvolfia verticillata. Picraline shows potent SGLT inhibitory activity. Group: Pharmaceutical. Alternative Names: (16R)-17-(Acetoxy)-2α,5α-epoxy-1,2-dihydroakuammilan-16-carboxylic acid methyl ester. CAS No. 2671-32-1. Pack Sizes: 1 mg. Product ID: NP0482. Molecular formula: C23H26N2O5. Mole weight: 410.5. Custom synthesis is available. Send your inquiries for more information. | London |
| 1-benzyl-4-ethoxybenzene | 1-benzyl-4-ethoxybenzene is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Group: Pharmaceutical. Alternative Names: Benzene,1-ethoxy-4-(phenylmethyl)-; 1-benzyl-4-ethoxy-benzene. CAS No. 35672-52-7. Pack Sizes: 100 mg. Product ID: B1370-377700. Molecular formula: C15H16O. Mole weight: 212.29. Custom synthesis is available. Send your inquiries for more information. | London |
| 1-Bromo-4-nitrobenzene-[d4] | 1-Bromo-4-nitrobenzene-[d4] - a deuterated analogue of 1-Bromo-4-nitrobenzene, a prominent organic compound studied for its CYP1A2 metabolism inhibitory potential in medicinal science. Its ubiquitous usage in pharmacokinetic studies of 1-Bromo-4-nitrobenzene-integrated drugs implicates its significance. It serves as an ideal candidate for studying the influence of deuterium substitution on drug pharmacokinetics and metabolism. Group: Pharmaceutical. Alternative Names: 4-Bromonitrobenzene-d4; 4-Nitrobromobenzene-d4; 4-Nitrophenyl Bromide-d4; NSC 3526-d4. CAS No. 350820-19-8. Pack Sizes: 25 mg. Product ID: BLP-010238. Molecular formula: C6D4BrNO2. Mole weight: 206.03. Custom synthesis is available. Send your inquiries for more information. | London |
| 1-chloro-2-(2-ethoxybenzyl)-4-iodobenzene | 1-chloro-2-(2-ethoxybenzyl)-4-iodobenzene is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Group: Pharmaceutical. CAS No. 2305949-36-2. Pack Sizes: 10 mg. Product ID: B1370-377692. Molecular formula: C15H14ClIO. Mole weight: 372.63. Custom synthesis is available. Send your inquiries for more information. | London |
| 1-epi-Edoxaban | An impurity of Edoxaban, an oral anticoagulant drug and a direct factor Xa inhibitor. Group: Pharmaceutical. Alternative Names: (1R)-Edoxaban. CAS No. 500572-10-1. Pack Sizes: 1 mg. Product ID: B2694-338760. Molecular formula: C24H30ClN7O4S. Mole weight: 548.06. Custom synthesis is available. Send your inquiries for more information. | London |
| 1-Ethyl-2-methylpyridinium bromide | 1-Ethyl-2-methylpyridinium bromide is a reagent used in the preparation and studies of MKT-077, which is an inhibitor of heat shock protein 70 as an anticancer agent. Group: Pharmaceutical. Alternative Names: Pyridinium, 1-ethyl-2-methyl-, bromide; N-ethyl-2-methylpyridinium bromide. CAS No. 32353-50-7. Pack Sizes: 25 g. Product ID: BB077788. Molecular formula: C8H12BrN. Mole weight: 202.09. Custom synthesis is available. Send your inquiries for more information. | London |
| 1-NA-PP1 | 1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. Group: Pharmaceutical. Alternative Names: 1-(Tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1-Naphthyl PP1. CAS No. 221243-82-9. Pack Sizes: 25 mg. Product ID: B2693-102805. Molecular formula: C19H19N5. Mole weight: 317.39. Custom synthesis is available. Send your inquiries for more information. | London |
| (1R,2S,5S)-2-Amino Edoxaban | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Group: Pharmaceutical. Alternative Names: Des((2-((5-chloro-2-pyridyl)amino)-2-oxo-acetyl))edoxaban; Edoxaban-M2. CAS No. 480450-71-3. Pack Sizes: 10 mg. Product ID: B1370-377831. Molecular formula: C17H27N5O2S. Mole weight: 365.5. Custom synthesis is available. Send your inquiries for more information. | London |
| ((1R,3R)-3-Amino-cyclopentyl)-carbamic Acid tert-Butyl Ester | ((1R,3R)-3-Amino-cyclopentyl)-carbamic Acid tert-Butyl Ester is used in the preparation of quinoline-3-carboxoamides as H-PGDS inhibitors as well as novel triazolo-pyrrolopyridines as Janus kinase 1 inhibitors. Group: Pharmaceutical. Alternative Names: tert-Butyl ((1R,3R)-3-aminocyclopentyl)carbamate; tert-butyl n-[(1r,3r)-3-aminocyclopentyl]carbamate; tert-Butyl rac-[(1R,3R)-3-aminocyclopentyl] carbamate; tert-Butyl ((1R,3R)-rel-3-aminocyclopentyl)carbamate; tert-Butyl N-[trans-3-aminocyclopentyl]carbamate; tert-Butyl [trans-3-aminocyclopentyl]carbamate. CAS No. 1009075-44-8. Pack Sizes: 1 g. Product ID: BB074488. Molecular formula: C10H20N2O2. Mole weight: 200.28. Custom synthesis is available. Send your inquiries for more information. | London |
| (1R, 3R, 4R)- Entecavir | An isomer of Entecavir. Entecavir is a reverse transcriptase inhibitor. It prevents the hepatitis B virus from multiplying and reduces the amount of virus in the body. Group: Pharmaceutical. Alternative Names: (1R,3R,4R)-Entecavir ; 2-Amino-9-[(1R,3R,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylidene cyclopentyl]-6,9-dihydro-3H-purin-6-one. CAS No. 1367369-76-3. Pack Sizes: 1 mg. Product ID: B0249-471009. Molecular formula: C12H15N5O3. Mole weight: 277.29. Custom synthesis is available. Send your inquiries for more information. | London |
| (1R, 3S, 4R)-ent-Entecavir | An isomer of Entecavir. Entecavir is a reverse transcriptase inhibitor. It prevents the hepatitis B virus from multiplying and reduces the amount of virus in the body. Group: Pharmaceutical. Alternative Names: 2-Amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-Purin-6-one. CAS No. 188399-46-4. Pack Sizes: 5 mg. Product ID: B0249-471013. Molecular formula: C12H15N5O3. Mole weight: 277.29. Custom synthesis is available. Send your inquiries for more information. | London |
| 1R-Dapagliflozin | 1R-Dapagliflozin is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Group: Pharmaceutical. Alternative Names: Dapagliflozin alfa-Isomer; (2R,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 1373321-04-0. Pack Sizes: 1 mg. Product ID: B2694-352557. Molecular formula: C21H25ClO6. Mole weight: 408.87. Custom synthesis is available. Send your inquiries for more information. | London |
| (1S,2S,5S)-7-Oxo-6-(phenylmethoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide | An impurity of Avibactam, which is a non-β lactam β-lactamase inhibitor that inactivates some β-lactamases. Group: Pharmaceutical. Alternative Names: Avibactam Impurity 27; (1S,2S,5S)-6-(Benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide. CAS No. 2064219-16-3. Pack Sizes: 25 mg. Product ID: B1370-059012. Molecular formula: C14H17N3O3. Mole weight: 275.3. Custom synthesis is available. Send your inquiries for more information. | London |
| (1S,3R)-RSL3 | (1S,3R)-RSL3 is a glutathione peroxidase 4 (GPX4) inhibitor with EC50 of 10 μM in cellular assay. It binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis. Group: Pharmaceutical. Alternative Names: RSL3; RSL3 (1S,3R-); 1S,3R-RSL3. CAS No. 1219810-16-8. Pack Sizes: 100 mg. Product ID: B0084-474402. Molecular formula: C23H21ClN2O5. Mole weight: 440.9. Custom synthesis is available. Send your inquiries for more information. | London |
| 21-Episerratenediol | 21-Episerratenediol is a natural triterpenoid found in the herbs of Lycopodium serratum, it exhibited a remarkable inhibitory effect on skin tumor promotion in an in vivo two-stage mouse skin carcinogenesis test using 7,12-dimethylbenz[a]anthracene as an initiator and TPA as a promoter which indicates that 21-episerratenediol might has the activity of anti-cancer. Uses: Anti-cancer; anti-tumor. Group: Pharmaceutical. Alternative Names: C(14a)-Homo-27-norgammacer-14-ene-3β,21β-diol. CAS No. 1449-06-5. Pack Sizes: 1 mg. Product ID: NP6511. Molecular formula: C30H50O2. Mole weight: 442.7. Custom synthesis is available. Send your inquiries for more information. | London |
| 2,3,4,6-Tetra-O-acetyl-a-D-mannopyranose | 2,3,4,6-Tetra-O-acetyl-a-D-mannopyranose is a key intermediary in the biomedical industry used in the synthesis of antiviral drugs. It contributes to the research and development of potent inhibitors for diseases such as HIV and influenza. Group: Pharmaceutical. Alternative Names: 2-O,3-O,4-O,6-O-Tetraacetyl-α-D-mannopyranose; α-D-Mannopyranose 2,3,4,6-tetraacetate; 2,3,4,6-O-Tetraacetyl-alpha-D-mannose; (2R,3R,4S,5S,6S)-2-(Acetoxymethyl)-6-hydroxytetrahydro-2H-pyran-3,4,5-triyl triacetate. CAS No. 22860-22-6. Pack Sizes: 5 g. Product ID: B1370-225349. Molecular formula: C14H20O10. Mole weight: 348.3. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-[[3,4-Dihydro-3-methyl-2,4-dioxo-6-[(3R)-3-piperidinylamino]-1(2H)-pyrimidinyl]methyl]benzonitrile | An impurity of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor in the class of oral antidiabetic drugs. Group: Pharmaceutical. Alternative Names: Benzonitrile, 2-[[3,4-dihydro-3-methyl-2,4-dioxo-6-[(3R)-3-piperidinylamino]-1(2H)-pyrimidinyl]methyl]-. CAS No. 2089611-85-6. Pack Sizes: 100 mg. Product ID: B1370-425895. Molecular formula: C18H21N5O2. Mole weight: 339.39. Custom synthesis is available. Send your inquiries for more information. | London |
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