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| Product | Description | |
|---|---|---|
| Monoethylene Glycol | Monarch Chemicals Ltd are a leading UK supplier of glycol products including Monoethylene Glycol and inhibited variations for closed circuit systems. Visit our website for more information. Uses: Closed circuit systems, Manufacturing, Antifreeze. Group: Glycols. Alternative Names: MEG. Pack Sizes: Poly, Drum, IBC and Bulk Tanker. |  United Kingdom |
| ISRIB | ISRIB is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Group: Pharmaceutical. CAS No. 1597403-47-8. Pack Sizes: 250 mg. Product ID: BAT-010737. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| ISRIB (mix-Isomer) | ISRIB (mix-Isomer), is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Group: Pharmaceutical. CAS No. 548470-11-7. Pack Sizes: 25 mg. Product ID: BAT-010736. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lumasiran | Lumasiran is a siRNA product that reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1). Group: Pharmaceutical. CAS No. 1834610-13-7. Pack Sizes: 5 mg. Product ID: B1370-072716. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PFK15 | PFK15 is a potent and selective inhibitor of 6-phosphofructo-2-kinase (PFKFB3) with IC50 of 207 nM. Overexpression of the PFKFB3 enzyme leads to high glycolytic metabolism, which is required for cancer cells to survive in the harsh tumor microenvironment. Group: Pharmaceutical. CAS No. 4382-63-2. Pack Sizes: 250 mg. Product ID: B2693-463353. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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