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| Product | Description | |
|---|---|---|
| Indoline-2-carboxylic acid | Indoline-2-carboxylic acid. CAS No. 78348-24-0. Product ID: C-04315. |  CARBONE SCIENTIFIC UK |
| Indoline-3-carboxylic acid | Indoline-3-carboxylic acid. CAS No. 39891-70-8. Product ID: C-04318. | CARBONE SCIENTIFIC UK |
| 1-Amino-2-methyl indoline hydrochloride | 1-Amino-2-methyl indoline hydrochloride. CAS No. 102789-79-7. Product ID: C-35101. | CARBONE SCIENTIFIC UK |
| 4-(2'-Bromoethyl)-3-chloro-1,3-dihydro-2-indoline-2-one | An intermediate of Ropinirole. Ropinirole acts as a D2, D3, and D4 dopamine receptor agonist with highest affinity for D2. It is weakly active at the 5-HT2, and α2 receptors and is said to have virtually no affinity for the 5-HT1, GABA, mAChRs, α1, and β-adrenoreceptors. Group: Pharmaceutical. Alternative Names: 4-(2-Bromoethyl)-3-chloro-1,3-dihydro-2H-indolin-2-one. CAS No. 120427-95-4. Pack Sizes: 100 mg. Product ID: B2694-055636. Molecular formula: C10H9BrClNO. Mole weight: 274.54. Custom synthesis is available. Send your inquiries for more information. |  London |
| DL-Indoline-2-carboxylic acid | 5g Pack Size. Group: Building Blocks. Formula: C9H9NO2. CAS No. 16851-56-2. Prepack ID : 19574131-5g. Molecular Weight : 163.18. |  |
| R)-(+)-Indoline-2-carboxylic acid | 5g Pack Size. Group: Building Blocks, Chiral Compounds, Indoles, Organics. Formula: C9H9NO2. CAS No. 98167-06-7. Prepack ID : 56971128-5g. Molecular Weight : 163.17. | |
| (S)-Indoline-2-carboxylic acid | (S)-Indoline-2-carboxylic acid. CAS No. 79815-20-6. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  Cenik Chemicals |
| S)-(-)-Indoline-2-carboxylic acid | 5g Pack Size. Group: Biochemicals, Building Blocks, Chiral Compounds, Ligands, Organics. Formula: C9H9NO2. CAS No. 79815-20-6. Prepack ID : 27353427-5g. Molecular Weight : 163.17. | |
| 3-(5-(2-aminopropyl)-7-cyanoindolin-1-yl)propyl benzoate (2R,3R)-2,3-dihydroxysuccinate | 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate is an intermediate of Silodosin, which is an α1-adrenergic receptor antagonist used for the treatment of benign prostatic hyperplasia. Group: Pharmaceutical. Alternative Names: 5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-7-carbonitrile-1H-indole (2R,3R)-2,3-dihydroxybutanedioate (1:1); (R)-5-(2-Aminopropyl)-1-(3-benzyloxypropyl)indoline-7-carbonitrile tartaric acid; (R)-3-(5-(2-Aminopropyl)-7-cyanoindolin-1-yl)propyl benzoate (2R,3R)-2,3-dihydroxysuccinate; 1H-Indole-7-carbonitrile, 5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-, (2R,3R)-2,3-dihydroxybutanedioate (1:1). CAS No. 239463-85-5. Pack Sizes: 1mg;1g;10g. Product ID: NP3475. Molecular formula: C22H25N3O2.C4H6O6. Mole weight: 513.54. Custom synthesis is available. Send your inquiries for more information. | London |
| Diclofenac EP Impurity E | Diclofenac EP Impurity E is an impurity of Diclofenac, which is a non-selective COX inhibitor used as a non-steroidal anti-inflammatory drug (NSAID). Group: Pharmaceutical. Alternative Names: Diclofenac sodium EP impurity E; Diclofenac potassium EP impurity E; 1,3-dihydro-2H-indol-2-one; 2H-Indol-2-one, 1,3-dihydro-; 1,3-Dihydro-2H-indol-2-one; 2-Indolinone; Oxindole; 2,3-Dihydro-1H-indol-2-one; 2-Indolone; 2-Oxindole; 2-Oxo-2,3-dihydroindole; 2-Oxoindole; 2-Oxoindoline; Indol-2(3H)-one; Indoline-2-one; NSC 274863; Oxindol. CAS No. 59-48-3. Pack Sizes: 1mg;1g;10g. Product ID: NP0047. Molecular formula: C8H7NO. Mole weight: 133.15. Custom synthesis is available. Send your inquiries for more information. | London |
| Isorhynchophylline | Rhynchophylline and isorhynchophylline act as noncompetitive antagonists of the NMDA receptor and that this property may contribute to the neuroprotective and anticonvulsant activity of the Uncaira species plant extracts. Rhynchophylline and isorhynchophylline have a non-competitive antagonistic effect on the NMDA-type ionotropic glutamate receptors, the present results suggest that these alkaloids exert their protective action against ischemia-induced neuronal damage by preventing NMDA, muscarinic M1, and 5-HT2 receptors-mediated neurotoxicity during ischemia. Group: Pharmaceutical. Alternative Names: methyl (E)-2-((3S,6'R,7'S,8a'S)-6'-ethyl-2-oxo-2',3',6',7',8',8a'-hexahydro-5'H-spiro[indoline-3,1'-indolizin]-7'-yl)-3-methoxyacrylate; Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethyl-1,2,2',3',6',7',8',8'a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,1'S,6'R,7'S,8'aS)-; 7-Isorhyncophylline; Corynoxan-16-carboxylic acid, 16,17-didehydro-17-methoxy-2-oxo-, methyl ester, (16E,20α)-; (+)-Isorhynchophylline; Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethyl-1,2,2',3',6',7',8',8'a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, [1'S-[1'α,6'α,7'β(E),8'aα]]-. CAS No. 6859-1-4. Pack Sizes: 50 mg. Product ID: NP0065. Molecular formula: C22H28N2O4. Mole weight: 384.47. Custom synthesis is available. Send your inquiries for more information | London |
| Nintedanib Impurity 6 (Intedanib Impurity 6) | BIBF 1202 is the major in-vivo metabolite of BIBF 1120, which is an oral triple angiokinase inhibitor targeting VEGFR, PDGFR, FGFR. It is a related compound of Intedanib, which is an indolinone derivative that inhibits angiokinase and an antitumor agent. It is a novel treatment modality in oncology through blockade of the vascular endothelial growth factor (VEGF) signaling pathway thus inhibition of tumor angiogenesis. Uses: Bibf 1202 is a novel treatment modality in oncology through blockade of the vascular endothelial growth factor (vegf) signaling pathway thus inhibition of tumor angiogenesis. Group: Pharmaceutical. Alternative Names: BIBF-1202; BIBF 1202; BIBF1202. (3Z)-2,3-Dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid;(Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1 -yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic acid;Nintedanib Impurity 5. CAS No. 894783-71-2. Pack Sizes: 50 mg. Product ID: B0084-474893. Molecular formula: C30H31N5O4. Mole weight: 525.6. Custom synthesis is available. Send your inquiries for more information. | London |
| Silodosin S-Isomer | An isomer of Silodosin, which is used in the treatment of the symptoms of an enlarged prostate (benign prostatic hyperplasia; BPH) in men. Group: Pharmaceutical. Alternative Names: Silodosin (S)-Isomer; (S)-Silodosin; 1-(3-Hydroxypropyl)-5-[(2S)-({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino)propyl]indoline-7-carboxamide; (S)-1-(3-Hydroxypropyl)-5-(2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)amino)propyl)indoline-7-carboxamide. CAS No. 2182279-45-2. Pack Sizes: 50 mg. Product ID: B2694-343858. Molecular formula: C25H32F3N3O4. Mole weight: 495.53. Custom synthesis is available. Send your inquiries for more information. | London |
| SU 4942 | SU 4942 is a modulator of tyrosine kinase signal transduction, targeting VEGF and ECGF. Group: Pharmaceutical. Alternative Names: SU 4942; SU-4942; SU4942. 3-(4-Bromobenzylidene)indoline-2-one. CAS No. 76086-99-2. Pack Sizes: 50 mg. Product ID: B0084-284846. Molecular formula: C15H10BrNO. Mole weight: 300.155. Custom synthesis is available. Send your inquiries for more information. | London |
| Trandolapril | Trandolapril is an angiotensin converting enzyme (ACE) inhibitor. It has a longer biological half-life and a high degree of lipophilicity than others. It is used to treat high blood pressure. It acts by competitive inhibition of ACE, which is a key enzyme in the renin-angiotensin system and plays an important role in regulating blood pressure. lt inhibits atherosclerosis1 and decreases the occurrence of atrial fibrillation2. It is marketed by Abbott Laboratories under the brand name Mavik. It has been listed. Uses: Trandolapril is used to treat high blood pressure. Group: Pharmaceutical. Alternative Names: RU 44570; (2S,3aR,7aS)-1-[(S)-N-[(S)-1-Carboxy-3-phenylpropyl] alanyl] hexahydro-2-indolinecarboxylic acid 1-ethyl ester. CAS No. 87679-37-6. Pack Sizes: 500 mg. Product ID: BAT-010063. Molecular formula: C24H34N2O5. Mole weight: 430.53. Custom synthesis is available. Send your inquiries for more information. | London |
| 1-(2,6-Dichlorophenyl)-2-indolinone | 1-(2,6-Dichlorophenyl)-2-indolinone. CAS No. 15362-40-0. | CARBONE SCIENTIFIC UK |
| 3-Acetonyl-3-hydroxyoxindole | 3-Hydroxy-3-acetonyloxindole is isolated from the herbs of Marsdenia tinctoria. Group: Pharmaceutical. Alternative Names: 33417-17-3;3-Hydroxy-3-acetonyloxindole;3-Hydroxy-3-(2-oxopropyl)-1,3-dihydro-2H-indol-2-one;3-Hydroxy-3-acetonyl-2-oxindole;3-hydroxy-3-(2-oxopropyl)-1H-indol-2-one;NSC 174507;1,3-Dihydro-3-hydroxy-3-(2-oxopropyl)-2H-indol-2-one;3-hydroxy-3-(2-oxopropyl)indolin-2-one;2-Indolinone,3-acetonyl-3-hydroxy-;3-Hydroxy-3-(2-oxo-propyl)-1,3-dihydro-indol-2-one;NSC659193;2H-INDOL-2-ONE, 1,3-DIHYDRO-3-HYDROXY-3-(2-OXOPROPYL)-;BRN 0182807;CBDivE_001774;3-acetonyl-3-hydroxyoxindole;4-21-00-06476 (Beilstein Handbook Reference);MLS000711569;CHEMBL1708591;SCHEMBL25435983;3-hydroxy-3-(2-oxopropyl)-2,3-dihydro-1H-indol-2-one;CBMTTXBZZZABGG-UHFFFAOYSA-N;DTXSID201036242;HMS2744D12;3-acetonyl-3-hydroxy-indolin-2-one;NSC174507;STK151695;STK846313;2-Indolinone, 3-acetonyl-3-hydroxy-;AKOS000274677;AKOS005626803;AKOS016038202;FS-8726;NSC-174507;NSC-659193;SDCCGMLS-0065646.P001;NCGC00245492-01;DA-48953;SMR000281336;1-(2,3-Dihydroxy-3H-indol-3-yl)acetone;CS-0017690;EN300-235764;1-(2,3-dihydroxy-3H-indol-3-yl)propan-2-one;2,3-Dihydroindole-3-ol-2-one, 3-acetomethyl-;SR-01000492393;SR-01000492393-1;Z56757977;F0896-0199;F1918-0060. CAS No. 33417-17-3. Pack Sizes: 1 mg. Product ID: NP0475. Molecular formula: C11H11NO3. Mole weight: 205.21. Custom synthesis is available. Send your inquiries for more information. | London |
| CID-25014542 | CID-25014542 is a Raf kinase inhibitor. Group: Pharmaceutical. Alternative Names: CID-25014542; CID25014542; CID 25014542. 5-Chloro-3-(3,5-dibromo-4-hydroxybenzylidene)indolin-2-one; (3Z)-5-chloro-3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-1H-indol-2-one. CAS No. 220904-99-4. Pack Sizes: 10 mg. Product ID: B0084-284809. Molecular formula: C15H8Br2ClNO2. Mole weight: 429.492. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK 2606414 | GSK 2606414 is a potent and selective PERK inhibitor that suppresses PERK activation in cells and inhibits the growth of a human tumor xenograft in mice. Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) is activated in response to a variety of endoplasmic reticulum stresses implicated in numerous disease states. Evidence that PERK is implicated in tumorigenesis and cancer cell survival stimulated our search for small-molecule inhibitors. Group: Pharmaceutical. Alternative Names: GSK2606414; GSK-2606414; GSK 2606414; GSK PERK Inhibitor. 1-(5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone. CAS No. 1337531-36-8. Pack Sizes: 100 mg. Product ID: B0084-462365. Molecular formula: C24H20F3N5O. Mole weight: 451.453. Custom synthesis is available. Send your inquiries for more information. | London |
| MAZ51 | MAZ51 is an indolinone that blocks the ligand-induced autophosphorylation of VEGFR-3 by VEGF-C. It was shown to inhibit proliferation and induce apoptosis of tumor cell lines. Group: Pharmaceutical. Alternative Names: (E)-3-((4-(dimethylamino)naphthalen-1-yl)methylene)indolin-2-one; 3-(4-Dimethylaminonaphthalen-1-ylmethylene)-1,3-dihydroindol-2-one; EX-A1914. CAS No. 163655-37-6. Pack Sizes: 100 mg. Product ID: B2693-195922. Molecular formula: C21H18N2O. Mole weight: 314.4. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Despropyl Ropinirole HCl | An impurity of Ropinirole. Ropinirole acts as a D2, D3, and D4 dopamine receptor agonist with highest affinity for D2. It is weakly active at the 5-HT2, and α2 receptors and is said to have virtually no affinity for the 5-HT1, GABA, mAChRs, α1, and β-adrenoreceptors. Group: Pharmaceutical. Alternative Names: 4-(2-(propylamino)ethyl)indolin-2-one hydrochloride. CAS No. 173990-76-6. Pack Sizes: 10 mg. Product ID: B2694-479262. Molecular formula: C13H18N2O.HCl. Mole weight: 254.76. Custom synthesis is available. Send your inquiries for more information. | London |
| Orantinib | Orantinib is a multiple receptor tyrosine kinase inhibitor with IC50s of 2.1 μM, 8 nM and 1.2 μM for VEGF-R1, PDGF-Rβ and FGF-R1, respectively. It has greatest potency against PDGFR autophosphorylation. Group: Pharmaceutical. Alternative Names: 3-(2,4-dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic Acid; 3-[2,4-Dimethyl-5-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propionic Acid; 3-[4-(2-Carboxyethyl)-3,5-dimethylpyrrol-2-methylidenyl]-2-indolinone; 5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid; NSC 702827; SU 6668; TSU-68. CAS No. 252916-29-3. Pack Sizes: 100 mg. Product ID: B0084-409435. Molecular formula: C18H18N2O3. Mole weight: 310.35. Custom synthesis is available. Send your inquiries for more information. | London |
| Oxindole (2-Indolinone) | 25g Pack Size. Group: Building Blocks, Indoles, Research Organics & Inorganics. Formula: C8H7NO. CAS No. 59-48-3. Prepack ID : 15523262-25g. Molecular Weight : 133.15. | |
| SU 4312 | SU 4312 is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 = 0.8 and 19.4 μM, respectively) wirth selectivity over EGFR and c-Src tyrosine kinases. Group: Pharmaceutical. Alternative Names: SU4312; SU-4312; 3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one; 2H-Indol-2-one, 3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro-; 2-Indolinone, 3-[p-(dimethylamino)benzylidene]-; 3-(4-Dimethylaminobenzylidenyl)-2-indolinone; 3-[[4-(Dimethylamino)phenyl]methylidene]-2,3-dihydro-1H-indol-2-one; DMBI; NSC 86429. CAS No. 5812-7-7. Pack Sizes: 50 mg. Product ID: B0084-357203. Molecular formula: C17H16N2O. Mole weight: 264.33. Custom synthesis is available. Send your inquiries for more information. | London |
| SU 5205 | SU5205 is a VEGFR2 inhibitor. Group: Pharmaceutical. Alternative Names: 3-(4-fluorobenzylidene)indolin-2-one; SU 5205; SU-5205; SU5205. CAS No. 3476-86-6. Pack Sizes: 50 mg. Product ID: B0084-284844. Molecular formula: C15H10FNO. Mole weight: 239.249. Custom synthesis is available. Send your inquiries for more information. | London |
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