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| Product | Description | |
|---|---|---|
| A 32390A | A 32390A is an antibiotic produced by Pyrenochaeta sp. (NRRL-5786). It has anti-gram-positive bacteria and fungi activity. It also inhibits the activity of dopamine tetra-hydroxylase, can reduce the level of norepinephrine in the heart and adrenal glands, and has a hypotensive effect on hypertensive rats. Group: Pharmaceutical. CAS No. 61241-59-6. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-03140. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Calcifediol monohydrate | Calcifediol monohydrate is a prehormone that is produced in the liver by hydroxylation of vitamin D3 (cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase. It can be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation. Uses: Bone density conservation agents. Group: Pharmaceutical. CAS No. 63283-36-3. Pack Sizes: 100 mg. Product ID: B2694-073954. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| DMOG | DMOG is an antagonist of α-ketoglutarate cofactor and inhibitor for HIF prolyl hydroxylase. Group: Pharmaceutical. CAS No. 89464-63-1. Pack Sizes: 1 g. Product ID: B1370-140847. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| FG-2216 | FG-2216, also known as YM311, is an orally bioavailable HIF-prolyl hydroxylase inhibitor. FG-2216 induced significant and reversible Epo induction in vivo. Group: Pharmaceutical. CAS No. 223387-75-5. Pack Sizes: 100 mg. Product ID: B1370-470907. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| IOX2 | IOX2 is a specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM. Group: Pharmaceutical. CAS No. 931398-72-0. Pack Sizes: 100 mg. Product ID: B2693-462381. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| L-α-Methyltyrosine | L-α-Methyltyrosine is a tyrosine hydroxylase inhibitor. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. It reduces the elevated levels of catecholamines associated with pheochromocytoma, thus preventing hypertension. It significantly inhibits COX-2 activity and has anti-inflammatory and anti-ulcer effects. Uses: L-α-methyltyrosine is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. Group: Pharmaceutical. CAS No. 672-87-7. Pack Sizes: 5 g. Product ID: BAT-008124. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Meldonium dihydrate | Mildronate is a potent γ-butyrobetaine hydroxylase inhibitor, with a half maximal inhibitory concentration (IC50) value of 62 μM. Uses: Adjuvants, immunologic. Group: Pharmaceutical. CAS No. 86426-17-7. Pack Sizes: 500 mg. Product ID: B0084-099416. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Nepicastat HCl | Nepicastat hydrochloride (SYN117, RS-25560-197) is an inhibitor of dopamine beta-hydroxylase that catalyzes the conversion of dopamine to norepinephrine. Nepicastat hydrochloride shows the selective and concentration-dependent inhibition effects on bovine and human dopamine-beta-hydroxylase activity in vitro. In vivo, Nepicastat hydrochloride increases dopamine content and dopamine/noradrenaline ratio in a dose-dependent manner. Nepicastat hydrochloride also produces the similar effects on noradrenaline, dopamine and dopamine/noradrenaline ratio in tissues and plasma of beagle dogs. Nepicastat is currently in Phase II clinical trials in patients with Posttraumatic Stress Disorder. Uses: Nepicastat is currently in phase ii clinical trials in patients with posttraumatic stress disorder. Group: Pharmaceutical. CAS No. 170151-24-3. Pack Sizes: 50 mg. Product ID: B0084-453616. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ro 61-8048 | Potent and competitive kynurenine 3-hydroxylase inhibitor (IC50 = 37 nM). Shows antidystonic, anticonvulsant and neuroprotective effects in vivo. Blood-brain barrier permeable. Orally active. Group: Pharmaceutical. CAS No. 199666-03-0. Pack Sizes: 50 mg. Product ID: B0084-272333. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sapropterin dihydrochloride | Sapropterin is a naturally occurring cofactor for phenylalanine hydroxylase. Under the trade name Kuvan, sapropterin dihydrochloride is approved for the treatment of hyperphenylalaninaemia and tetrahydrobiopterin deficiency. Group: Pharmaceutical. CAS No. 69056-38-8. Pack Sizes: 500 mg. Product ID: B0046-097081. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Telotristat Etiprate | Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. Uses: Combination therapy of somatostatin analogue (ssa) and telotristat ethyl. Group: Pharmaceutical. CAS No. 1137608-69-5. Pack Sizes: 10 mg. Product ID: B0084-286447. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tetrahydropiperine | Tetrahydropiperine is a piperine alkaloid originally isolated from P. longum. It acts as an agonist of transient receptor potential vanilloid type 1 (TRPV1). It inhibits the cytochrome P450 (CYP) isoform CYP1A1/arylhydrocarbon hydroxylase (AHH) and 7-methoxycoumarin O-demethylase (MOCD) activity in rat liver microsomes. Group: Pharmaceutical. CAS No. 23434-88-0. Pack Sizes: 100 mg. Product ID: B2703-059108. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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