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| Product | Description | |
|---|---|---|
| 3'-O-Methylguanosine | 3'-O-Methylguanosine is an endogenous methylated nucleoside found in human fluids. Methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls. DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. When chemical bonds to DNA, it becomes damaged and proper and complete replication cannot occur to make the normal intended cell. A DNA adduct is an abnormal piece of DNA covalently-bonded to a cancer-causing chemical. This has shown to be the start of a cancerous cell, or carcinogenesis. DNA adducts in scientific experiments are used as bio-markers and as such are themselves measured to reflect quantitatively, for comparison, the amount of cancer in the subject. Group: Pharmaceutical. CAS No. 10300-27-3. Pack Sizes: 50 mg. Product ID: B2706-306475. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| α-CGRP (human) TFA | α-CGRP (human) is an endogenous calcitonin gene-related peptide receptor (CGRP) agonist. Group: Pharmaceutical. Pack Sizes: 50 mg. Product ID: BAT-016129. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Byakangelicin | Byakangelicin is an effective inhibitor of sex hormones and affects the catabolism of endogenous hormones. It directly affects the cytochrome P450 isoform (CY) P3A4 in human hepatocytes. It is an inhibitor of aldose reductase used in the treatment of diabetic cataracts. Byakangelicin is a natural coumarin compound found in Murraya koenigii, Triphasia trifoliata, and other organisms. Group: Pharmaceutical. CAS No. 482-25-7. Pack Sizes: 10 mg. Product ID: NP1139. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ethynyl estradiol | Ethinyl Estradiol is a derivative of 17β-estradiol (E2), the major endogenous estrogen in humans. EE2 is an orally bioactive estrogen used in many formulations of combined oral contraceptive pills and is one of the most commonly used medications for this purpose. Uses: Component of oral contraceptive pills. Group: Pharmaceutical. CAS No. 57-63-6. Pack Sizes: 10 g. Product ID: NP3296. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gastrin I (human) | Gastrin I (human) is an endogenous peptide produced by stomach and it acts as a selective CCK2 receptor agonist. Gastrin I stimulates gastric acid secretion in vivo, and increases levels of cytosolic calcium in isolated rabbit stomach parietal cells (EC50 = 11 nM). Group: Pharmaceutical. CAS No. 10047-33-3. Pack Sizes: 2.5 mg. Product ID: BAT-006092. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| [Leu15]-Gastrin I (human) | A derivative of Gastrin I (human), an endogenous peptide produced by stomach and it acts as a selective CCK2 receptor agonist. Group: Pharmaceutical. CAS No. 39024-57-2. Pack Sizes: 5 mg. Product ID: BAT-006204. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Netupitant | Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively binds to and blocks the human substance P/NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in the prevention of chemotherapy-induced nausea and vomiting (CINV). SP is found in neurons of vagal afferent fibers innervating the brain-stem nucleus tractus solitarii and the area postrema, which contains the chemoreceptor trigger zone (CTZ), and may be elevated in response to chemotherapy. The NK-receptor is a G-protein receptor coupled to the inositol phosphate signal-transduction pathway and is found in both the nucleus tractus solitarii and the area postrema. On 10/10 2014 FDA approved netupitant for the treatment of nausea and vomiting in patients undergoing cancer chemotherapy. Group: Pharmaceutical. CAS No. 290297-26-6. Pack Sizes: 50 mg. Product ID: B2693-465324. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Neuropeptide Y (human, rat) | Neuropeptide Y (human, rat) is a widely distributed endogenous neuropeptide involved in the control of food intake, sexual behavior and blood pressure. NPY has also been shown to interact with the immune system, promoting gastrointestinal inflammation, as well as exhibiting an antimicrobial effect against several gut bacteria. Group: Pharmaceutical. CAS No. 90880-35-6. Pack Sizes: 5 mg. Product ID: BAT-010562. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PHM-27 (human) | PHM-27 (human) is an endogenous peptide analog of human prepro-VIP and potent agonist for the human calcitonin receptor. Group: Pharmaceutical. CAS No. 87403-73-4. Pack Sizes: 1 mg. Product ID: BAT-006086. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Progesterone | Progesterone is a natural steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Uses: Endogenous progesterone receptor (pr) agonist. Group: Pharmaceutical. CAS No. 57-83-0. Pack Sizes: 100 g. Product ID: B0084-474244. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Progesterone 6-Oxo Impurity | An impurity of Progesterone. Progesterone is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Progesterone is also a crucial metabolic intermediate in the production of other endogenous steroids, including the sex hormones and the corticosteroids, and plays an important role in brain function as a neurosteroid. Group: Pharmaceutical. CAS No. 2243-8-5. Pack Sizes: 1 g. Product ID: B2694-175130. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Progesterone EP Impurity B | A metabolite of Progesterone.Progesterone is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Progesterone is also a crucial metabolic intermediate in the production of other endogenous steroids, including the sex hormones and the corticosteroids, and plays an important role in brain function as a neurosteroid. Uses: Progestins. Group: Pharmaceutical. CAS No. 145-14-2. Pack Sizes: 5 mg. Product ID: NP6066. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Progesterone EP Impurity C | An impurity of Progesterone.Progesterone is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Progesterone is also a crucial metabolic intermediate in the production of other endogenous steroids, including the sex hormones and the corticosteroids, and plays an important role in brain function as a neurosteroid. Group: Pharmaceutical. CAS No. 145-15-3. Pack Sizes: 10 mg. Product ID: B2694-166567. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Progesterone EP Impurity D | An impurity of Progesterone.Progesterone is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Progesterone is also a crucial metabolic intermediate in the production of other endogenous steroids, including the sex hormones and the corticosteroids, and plays an important role in brain function as a neurosteroid. Group: Pharmaceutical. CAS No. 5035-9-6. Pack Sizes: 100 mg. Product ID: B1756-483367. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Progesterone EP Impurity G | An impurity of Progesterone.Progesterone is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Progesterone is also a crucial metabolic intermediate in the production of other endogenous steroids, including the sex hormones and the corticosteroids, and plays an important role in brain function as a neurosteroid. Group: Pharmaceutical. CAS No. 2257421-79-5. Pack Sizes: 1 mg. Product ID: B2694-483378. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PTC-209 | PTC-209 is a potent BMI-1 inhibitor with potential anticancer activity. PTC-209 inhibits endogenous BMI-1 expression in human colorectal HCT116 and human fibrosarcoma HT1080 tumor cells. Group: Pharmaceutical. CAS No. 315704-66-6. Pack Sizes: 25 mg. Product ID: B0084-462442. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| [Pyr1]-Apelin-13 | [Pyr1]-Apelin-13 is the highly potent pyroglutamylated form of apelin-13, which is an endogenous ligand of the G protein-coupled APJ receptor with EC50 value of 0.37 nM. It is the major apelin form in human plasma and heart, which the N-terminal glutamine residue is cyclized to pyroglutamic acid. It exhibits higher APJ agonist potency than Apelin-13. It has antipyretic and vasoconstrictor effects in vitro and in vivo. It is widely used for studying APJ-mediated cellular and physiological functions both in cultures and in animals in vivo. It is reactive toward human, rat, bovine and murine species. Group: Pharmaceutical. CAS No. 217082-60-5. Pack Sizes: 2.5 mg. Product ID: BAT-006078. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Silybin A | Silymarin, isolated from the herb of Silybum marianum (L.) Gaertn, is an antioxidant or free radical scavenger. Silymarin and Prunella vulgaris improve antioxidant status in blood and liver, and positively affect plasma lipoprotein profile in an experimental model of dietary induced hypertriglyceridemia. Both in vitro and animal research suggest that Silymarin has hepatoprotective (antihepatotoxic) properties that protect liver cells against toxins. Silymarin has also demonstrated in vitro anti-cancer effects against human prostate adenocarcinoma cells, estrogen-dependent human breast carcinoma cells, human ectocervical carcinoma cells, human colon cancer cells, and both small and nonsmall human lung carcinoma cells. Silymarin treatment in type II diabetic patients for 4 months has a beneficial effect on improving the glycemic profile. Treatment with silymarin may reduce the lipoperoxidation of cell membranes and insulin resistance, significantly decreasing endogenous insulin overproduction and the need for exogenous insulin administration. Silybin is a natural compound also can be used in cosmetics material. Uses: Protective agents. Group: Pharmaceutical. CAS No. 22888-70-6. Pack Sizes: 100 g. Product ID: NP1920. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Neuropeptide AF (93-110), Human TFA salt | Neuropeptide AF, an endogenous anti-opioid peptide involved in pain modulation and endocrine functions, may also regulate metabolism via stimulation of β-adrenoceptor expression in adipocytes. Group: Pharmaceutical. Pack Sizes: 1 mg. Product ID: BAT-016479. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PACAP (1-27), human, ovine, rat | Pituitary adenylate cyclase activating polypeptide (PACAP 1-27) is an endogenous neuropeptide showing considerable homology with vasoactive intestinal peptide (VIP). It is a potent PACAP receptor agonist. Group: Pharmaceutical. CAS No. 127317-03-7. Pack Sizes: 1 mg. Product ID: BAT-006206. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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