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| Product | Description | |
|---|---|---|
| 3-Tert-Butyldimethylsilyl-2-propyn-1-ol | 3-Tert-Butyldimethylsilyl-2-propyn-1-ol, a widely used chemical compound in organic synthesis, serves as a safeguarding agent for alcohols, impeding undesired chemical reactions. It displays versatility in various applications ranging from stable protecting group synthesis to the development of potent drugs such as Atazanavir, a prominent HIV protease inhibitor. The compound's multifunctional competence and adaptability make it an indispensable component of organic synthesis. Group: Pharmaceutical. CAS No. 120789-51-7. Pack Sizes: 1 g. Product ID: B2699-232842. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Acetylpepstatin | Acetylpepstatin is an aspartyl protease inhibitor that is effective against HIV-1 and HIV-2 protease. Group: Pharmaceutical. CAS No. 28575-34-0. Pack Sizes: 10 mg. Product ID: BAT-010206. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl-pepstatin | Acetyl-pepstatin is a potent classical inhibitor of aspartic proteases (PRs) with XMRV PR and HIV-1 PR Ki values of 712 nM and 13 nM. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl Pepstatin | Acetyl Pepstatin is a high affinity HIV-1 protease inhibitor and aspartic protease inhibitor. It inhibits HIV-1 protease with Ki value of 20 nM at pH 4.7 and HIV-2 protease with Ki value of 5 nM at pH 4.7. It is used as an antiviral agent. Group: Pharmaceutical. CAS No. 11076-29-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-010271. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2 | Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2 is an HIV-1 protease inhibitor whose sequence is derived from the cleavage site of the viral gag-pol poly-protein. Electron density studies have shown that this inhibitor binds to the active site of the HIV-1 protease. Group: Pharmaceutical. CAS No. 128657-47-6. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015166. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Atazanavir | Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir. Group: Pharmaceutical. CAS No. 198904-31-3. Pack Sizes: 1 g. Product ID: B0084-062263. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bevirimat | Bevirimat, also known as MPC-4326 and PA-457, is an anti-HIV drug derived from a betulinic acid-like compound, first isolated from Syzygium claviflorum, a Chinese herb. It is believed to inhibit HIV by a novel mechanism, so-called maturation inhibition. Like protease inhibitors, bevirimat and other maturation inhibitors interfere with protease processing of newly translated HIV polyprotein precursor, called gag. Bevirimat prevents this viral replication by specifically inhibiting cleavage of the capsid protein (CA) from the SP1 spacer protein. Group: Pharmaceutical. CAS No. 174022-42-5. Pack Sizes: 5 mg. Product ID: B0084-244897. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Darunavir | Darunavir is a second generation protease inhibitor that targets the HIV-1 protease. It demonstrates extremely potent activity against the infectivity and replication of various strains of HIV-1, including several that are resistant to first generation protease inhibitors (IC50s = 3-30 nM). Darunavir has been reported to inhibit both cell-free diffusion and cell-to-cell spread of HIV-1 with IC50 values of 2.5 and 2.8 nM, respectively. Uses: Hiv protease inhibitors. Group: Pharmaceutical. CAS No. 206361-99-1. Pack Sizes: 50 mg. Product ID: B0084-062615. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Darunavir Ethanolate | Darunavir Ethanolate is a nonpeptidic HIV protease inhibitor, used to treat HIV infection. Uses: Hiv protease inhibitors. Group: Pharmaceutical. CAS No. 635728-49-3. Pack Sizes: 1 g. Product ID: B0084-459375. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Escin Ia | Escin Ia is a triterpenoid saponin isolated from A. chinensis. It was shown to inhibit HIV-1 protease with IC50 value of 35 μM. Group: Pharmaceutical. CAS No. 123748-68-5. Pack Sizes: 10 mg. Product ID: NP7065. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| γ-Mangostin | gamma-Mangostin isolated from the fruit of Garcinia cambogia is an HIV protease inhibitor. gamma-Mangostin is cytotoxic to HL-60, SMMC-7721, A549, MCF-7, and SW480 cancer cells and BEAS-2B non-cancerous pulmonary epithelial cells in vitro (IC50s = 7.39, 6.57, 10.07, 5.33, 8.4, and 7.43 μM, respectively). Uses: Hiv protease inhibitor. Group: Pharmaceutical. CAS No. 31271-07-5. Pack Sizes: 25 mg. Product ID: BBF-04088. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ganoderiol F | Lansiumarin C is a natural coumarin found in the branches of Clausena lansium. and found to induce senescence of cancer cell lines, it induces growth arrest of cancer cell lines HepG2, Huh7 and K562; activation of the mitogen-activated protein kinase EKR and up-regulation of cyclin-dependent kinase inhibitor p16 were found in early stages of Ganoderiol F treatment and were presumed to cause cell-cycle arrest and trigger premature senescence of HepG2 cells; suggests that the growth-arrest and senescence induction capability on cancer cells suggest anticancer potential of Ganoderiol F. It could be developed further as both anti-HIV and antimalaria.In Compared to plasmepsin I, ganoderiol-F is higher towards HIV-1 protease. Uses: Anti-inflammatory; anti-hiv. Group: Pharmaceutical. CAS No. 114567-47-4. Pack Sizes: 1 mg. Product ID: NP6829. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JE-2147 | JE-2147 is a dipeptide HIV protease inhibitor (PI) that is effective against a wide spectrum of HIV-1, HIV-2, simian immunodeficiency virus, and various clinical HIV-1 strains in vitro. Group: Pharmaceutical. CAS No. 186538-00-1. Pack Sizes: 10 mg. Product ID: B2693-008706. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lopinavir | An antiretroviral medication acts as a protease inhibitor. It is a co-formulation with a sub-therapeutic dose of ritonavir, as a component of combination therapy to treat HIV/AIDS. Group: Pharmaceutical. CAS No. 192725-17-0. Pack Sizes: 1 g. Product ID: B0084-086623. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Nelfinavir Impurities | Nelfinavir Impurities are crucial analytical tools in the biomedical industry for ensuring the quality and safety of Nelfinavir, an antiretroviral protease inhibitor used in treating HIV-1 infections. These impurities aid in developing purification processes and conducting rigorous stability studies, thereby enhancing therapeutic efficacy and patient safety. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Pepstatin A | Pepstatin A is a potent aspartic protease inhibitor, and also inhibits HIV replication.It is a hexa-peptide containing the unusual amino acid statine (Sta, (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid), having the sequence Isovaleryl-Val-Val-Sta-Ala-Sta (Iva-Val-Val-Sta-Ala-Sta). Uses: Protease inhibitors. Group: Pharmaceutical. CAS No. 26305-03-3. Pack Sizes: 500 mg. Product ID: BAT-010775. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ritonavir | Ritonavir is an HIV protease inhibitor. It is often used in a low dose with another protease inhibitor lopinavir. Ritonavir was approved for COVID-19 treatment in combination with Nirmatrelvir. Group: Pharmaceutical. CAS No. 155213-67-5. Pack Sizes: 1 g. Product ID: NP2679. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ritonavir Impurities | Ritonavir Impurities, essential constituents in pharmaceutical realms, play a critical role in quality assurance and antiretroviral research. Their presence aids in discerning drug stability, efficiency, and safety parameters. As a protease inhibitor pivotal in HIV-1 management, ritonavir's impurities are indispensable for refining its formulation strategies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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