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100g Pack Size. Group: Biochemicals. Formula: C5H5N5O. CAS No. 73-40-5. Prepack ID : 52634391-100g. Molecular Weight : 151.13.
Guanine (2-Amino-6-hydroxypurine)
25g Pack Size. Group: Biochemicals. Formula: C5H5N5O. CAS No. 73-40-5. Prepack ID : 52634391-25g. Molecular Weight : 151.13.
Guanine hydrochloride
25g Pack Size. Group: Biochemicals. Formula: C5H5N5O · HCl. CAS No. 635-39-2. Prepack ID : 11311745-25g. Molecular Weight : 187.59.
9-(b-D-Xylofuranosyl)guanine
9-(β-D-Xylofuranosyl)guanine, a renowned biomedicine product, is widely recognized for its efficaciousness in combating viral infections, particularly those induced by herpes viruses. Functioning as an antiviral agent, this compound effectively hinders the proliferation of viral DNA, thereby mitigating viral burden and alleviating symptoms related to herpes virus infections. Group: Pharmaceutical. Alternative Names: 6H-Purin-6-one, 1,9-dihydro-2-amino-9-beta-D-xylofuranosyl-; 2-Amino-9-(β-D-xylofuranosyl)-1,9-dihydro-6H-purin-6-one; 2-Amino-9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2-Amino-1,9-dihydro-9-β-D-xylofuranosyl-6H-purin-6-one; Guanine, 9-β-D-xylofuranosyl-; 9-β-D-Xylofuranosylguanine; NSC 115607. CAS No. 27462-39-1. Pack Sizes: 100 mg. Product ID: B1370-146000. Molecular formula: C10H13N5O5. Mole weight: 283.24. Custom synthesis is available. Send your inquiries for more information.
N2-Isobutyryl-O6-(4-pivaloyloxybenzyl)-7'-OH-N-trityl-morpholino guanine is a potent compound commonly used in biomedicine. It functions as an effective inhibitor for certain diseases by targeting specific enzymes involved in their progression. Group: Pharmaceutical. CAS No. 2072145-52-7. Pack Sizes: 10 mg. Product ID: B1370-340029. Molecular formula: C45H48N6O6. Mole weight: 768.9. Custom synthesis is available. Send your inquiries for more information.
An impurity of Famciclovir, a guanine analogue antiviral drug used for the treatment of various herpesvirus infections. Group: Pharmaceutical. CAS No. 174155-69-2. Pack Sizes: 10 mg. Product ID: B1370-244938. Molecular formula: C15H21N5O4. Mole weight: 335.36. Custom synthesis is available. Send your inquiries for more information.
An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Group: Pharmaceutical. Alternative Names: AC1NANKY; 2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl benzoate; 6H-Purin-6-one, 2-amino-9-[[2-(benzoyloxy)ethoxy]methyl]-1,9-dihydro-; SCHEMBL8660736; 9-(benzoyloxyethoxymethyl)guanine. CAS No. 59277-91-7. Pack Sizes: 50 mg. Product ID: B0093-007231. Molecular formula: C15H15N5O4. Mole weight: 329.316. Custom synthesis is available. Send your inquiries for more information.
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2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine
It is the impurity C of Clofarabine and is also an anticancer agent. Group: Pharmaceutical. Alternative Names: 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)guanine; 2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine; 2'-deoxy-2'-fluoro-arabino-guanosine; 2'-FANA-Gr; 2-Amino-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-1H-purin-6(9H)-one; 2-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one; 2'-Fluoro-Arabinoguanosine; NUK-2. CAS No. 103884-98-6. Pack Sizes: 250 mg. Product ID: B2706-081123. Molecular formula: C10H12FN5O4. Mole weight: 285.23. Custom synthesis is available. Send your inquiries for more information.
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2'-O,4'-C-Methyleneguanosine
2'-O,4'-C-Methyleneguanosine, a modified nucleoside molecule, has demonstrated effective outcomes in the domain of antiviral therapeutics, exemplifying excellent potential as a therapeutic agent for hepatitis C and West Nile virus infections. Substantiated by its unique mechanism of action- hindering viral RNA polymerase, a critical enzyme necessary for viral replication, it is deemed a highly potent approach for viral inhibition. Furthermore, this particular compound presents an enticing opportunity for its application as an antitumor agent, drawing interest from scientific communities. Group: Pharmaceutical. Alternative Names: LNA-G; 2-amino-9-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-1H-purin-6-one; 1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)guanine; 2-Amino-9-[2,5-anhydro-4-(hydroxymethyl)-α-L-lyxofuranosyl]-1,9-dihydro-6H-purin-6-one. CAS No. 207131-16-6. Pack Sizes: 100 mg. Product ID: B2706-038100. Molecular formula: C11H13N5O5. Mole weight: 295.25. Custom synthesis is available. Send your inquiries for more information.
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4'-Thioguanosine
4'-Thioguanosine, a highly regarded compound, plays a pivotal role in the research of diverse conditions, encompassing viral infections, autoimmune disorders and specific cancer forms. Employing a unique mechanism, 4'-Thioguanosine disrupts viral replication processes while concurrently regulating immune responses, culminating in a notable reduction in viral load and corresponding inflammation levels. Group: Pharmaceutical. Alternative Names: 4'-O-Thiaguanosine; Guanosine, 4'-thio-; 9-(4-Thio-beta-D-ribofuranosyl)guanine; 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-1H-purin-6-one. CAS No. 74249-68-6. Pack Sizes: 100 mg. Product ID: B1370-340259. Molecular formula: C10H13N5O4S. Mole weight: 299.31. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-2'-Fluoro-N2-isobutyryl-2'-Deoxy-guanosine 3'-CE phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It features a 5'-dimethoxytrityl (DMT) protecting group at the 5'-hydroxyl position, a 2'-fluoro modification to enhance stability and binding affinity, an N2-isobutyryl group protecting the exocyclic amine of the guanine base, and a cyanoethyl (CE) group on the 3'-phosphoramidite. These modifications make it suitable for synthesizing oligonucleotides with improved resistance to enzymatic degradation and enhanced hybridization properties, which are crucial for applications in research, diagnostics, and therapeutics. Group: Pharmaceutical. Alternative Names: 2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine 3'-CE phosphoramidite; 2'-F-iBu-G-CEP; 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)?-Guanosine 3'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]; DMT-2'Fluoro-dG(iBu) Phosphoramidite; 2'-F-dG(iBu) 3'-CE phosphoramidite; DMT-2'-F-dG(iBu)-CE Phosphoramidite; 2'-F-dG(iBu)-CE Phosphoramidite; 2'-Fluoro-N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine-3'-CE-Phosphoramidite. CAS No. 144089-97-4. Pack Sizes: 5 g. Product ID: B2706-291975. Molecular formula: C44H53FN7O8P. Mole weight: 857.91. Custom synthesis is available. Send your inquiries for more information.
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5'-O-DMT-N2-isobutyrylguanosine
5'-O-DMT-N2-isobutyrylguanosine is a biomedicine product commonly used in the field of nucleic acid research. This compound is a modified form of guanosine and is often utilized as a substrate to study various enzymatic reactions related to DNA and RNA synthesis. It plays a crucial role in investigating the functions of guanine derivatives, offering insights into potential therapeutic approaches for diseases involving nucleic acid metabolism. Group: Pharmaceutical. Alternative Names: 5'-DMT-ibu-rG; N2-iso-Butyryl-5'-O-(4,4'-dimethoxytrityl)guanosine; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-guanosine; N-[9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide; 5'-O-DMT-ibu-rG; 5'-DMT Guanosine (n-ibu). CAS No. 81246-83-5. Pack Sizes: 25 g. Product ID: B1370-340277. Molecular formula: C35H37N5O8. Mole weight: 655.7. Custom synthesis is available. Send your inquiries for more information.
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Acyclovir
Aciclovir is a synthetic nucleoside analogue active against herpesviruses. It is primarily used for the treatment of herpes simplex virus infections, chickenpox and shingles. Group: Pharmaceutical. Alternative Names: Valaciclovir Impurity B; Valaciclovir hydrochloride EP Impurity B; Valaciclovir hydrochloride hydrate EP Impurity B; Valaciclovir EP Impurity B; 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one; 2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one; 2-Amino-9-(2-hydroxy-ethoxymethyl)-1,9-dihydro-purin-6-one; 2-Amino-9-(2-hydroxy-ethoxymethyl)-3,9-dihydro-purin-6-one; 2-Amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one; 2-Amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one; 2-Amino-9-[(2-hydroxyethoxy)methyl]-9H-purin-6-ol; 9-(2-Hydroxyethoxymethyl)guanine; Acicloftal; Aciclovir; Acivir; ACV; Acyclo V; Acycloguanosine; Avirase; Axiluowei; Cargosil; Gerpevir; Herpevir; Lovir; Novirus; NSC 645011; Poviral; Rouz-Aciclovir; Vicclox; Vipral; Virax; Virless; Virorax; Virovir; Wellcome 248U; Zirax; Zovirax; Zyclir. CAS No. 59277-89-3. Pack Sizes: 25 g. Product ID: BBF-04163. Molecular formula: C8H11N5O3. Mole weight: 225.2. Custom synthesis is available. Send your inquiries for more information.
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Acyclovir-5'-triphosphate
Acyclovir-5'-triphosphate is a derivative of Acyclovir, an agent resistant to herpesvirus DNA polymerase. Uses: Acyclovir-5'-triphosphate is a derivative of acyclovir. Group: Pharmaceutical. Alternative Names: Acyclovir triphosphate; AcycloGTP; Acycloguanosine triphosphate; Aciclovir-triphosphate; 9-(2-Hydroxyethoxymethyl)guanine triphosphate; Aciclvir-triphosphate; Triphosphoric acid, P-(2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl) ester. CAS No. 66341-18-2. Pack Sizes: 100 μL. Product ID: B1370-272642. Molecular formula: C8H14N5O12P3. Mole weight: 465.14. Custom synthesis is available. Send your inquiries for more information.
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Acyclovir triphosphate (triethylammonium salt form)
An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Group: Pharmaceutical. Alternative Names: 9-(2-Hydroxyethoxymethyl)guanine triphosphate triethylammonium; ACGTP (triethylammonium salt form). CAS No. 186367-53-3. Pack Sizes: 1 mg. Product ID: B0093-007251. Molecular formula: C8H14N5O12P3.C6H15N. Mole weight: 465.147 (free acid). Custom synthesis is available. Send your inquiries for more information.
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BI-3406
BI-3406 is a potent and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1). SOS1 is the guanine nucleotide exchange factor (GEF) and activator of RAS, and mutants of RAS are major oncogenes and occur in many human cancers. Inhibition of SOS1 in a mutant KRAS cell line can suppress tumor growth. Group: Pharmaceutical. Alternative Names: BI 3406; BI3406. CAS No. 2230836-55-0. Pack Sizes: 5 mg. Product ID: B2693-363125. Molecular formula: C23H25F3N4O3. Mole weight: 462.5. Custom synthesis is available. Send your inquiries for more information.
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Cyclophosphamide monohydrate
Cyclophosphamide monohydrate is a nitrogen mustard alkylating agent, which attaches the alkyl group to the guanine base of DNA. It is used to treat cancers and autoimmune diseases. Group: Pharmaceutical. Alternative Names: Cyclophosphamide hydrate; Cytoxan; Endoxon. CAS No. 6055-19-2. Pack Sizes: 25 g. Product ID: B0046-464089. Molecular formula: C7H15Cl2N2O2P·H2O. Mole weight: 279.1. Custom synthesis is available. Send your inquiries for more information.
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Ganciclovir EP Impurity C
Ganciclovir EP Impurity C is an Impurity of Ganciclovir. It is a sugar modified acyclic analogue of guanosine. It has potential to exhibit virucidal activity. Group: Pharmaceutical. Alternative Names: 2'-Monodehydroxy-2'-chloro Ganciclovir; 9-[[2-Chloro-1-(hydroxymethyl)ethoxy]methyl]guanine; 2-Amino-9-[[2-chloro-1-(hydroxymethyl)ethoxy]methyl]-1,9-dihydro-6H-purin-6-one. CAS No. 108436-36-8. Pack Sizes: 10 mg. Product ID: B2694-471961. Molecular formula: C9H12ClN5O3. Mole weight: 273.68. Custom synthesis is available. Send your inquiries for more information.
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Golgicide A
Golgicide A is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1. Golgicide A inhibited HSV-1 entry via beta-galactosidase reporter assay and impaired incoming virus transport to the nuclear periphery. Group: Pharmaceutical. Alternative Names: GCA; (3aR,9bS)-rel-6,8-Difluoro-3a,4,5,9b-tetrahydro-4-(3-pyridinyl)-3H-cyclopenta[c]quinoline; 3H-Cyclopenta[c]quinoline, 6,8-difluoro-3a,4,5,9b-tetrahydro-4-(3-pyridinyl)-, (3aR,9bS)-. CAS No. 1139889-93-2. Pack Sizes: 100 mg. Product ID: B1370-261662. Molecular formula: C17H14F2N2. Mole weight: 284.3. Custom synthesis is available. Send your inquiries for more information.
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Guanosine 3',5'-cyclic monophosphate
Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'-and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. 3',5'-cyclic GMP is a 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine. It has a role as a plant metabolite, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a guanyl ribonucleotide and a 3',5'-cyclic purine nucleotide. It is a conjugate acid of a 3',5'-cyclic GMP(1-). Group: Pharmaceutical. Alternative Names: 3:5-CGMP; D-Guanosine 3',5'-cyclic monophosphate; 3',5'-cyclic GMP; 2-Amino-6-oxo-6,9-dihydro-1H-purine 3-oxide; guanine-3-N-oxide; 2-Amino-1,7-dihydro-6H-purin-6-one 3-oxide; Cyclic guanosine monophosphate. CAS No. 7665-99-8. Pack Sizes: 250 mg. Product ID: B1370-013547. Molecular formula: C10H12N5O7P. Mole weight: 345.21. Custom synthesis is available. Send your inquiries for more information.
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Lanreotide
Laromustine is a sulfonyl hydrazine prodrug with antineoplastic activity. Laromustine releases the DNA chloroethylating agent 90CE after entering the blood stream; 90CE chloroethylates alkylates the 06 position of guanine, resulting in DNA crosslinking, strand breaks, chromosomal aberrations, and disruption of DNA synthesis. Intracellular metabolism of this agent also releases methyl isocyanate which inhibits 06-alkyl-guanine transferase, an enzyme involved with DNA repair. Group: Pharmaceutical. Alternative Names: Angiopeptin; Autogel; BIM 23014; DC 13-116; Dermopeptin; Ipstyl; L-Autogel; Lanreotide Autogel; Somatulin; Somatulin-Autogel; Somatuline Depot; L-Threoninamide, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2→7)-disulfide; H-D-2Nal-Cys(1)-Tyr-D-Trp-Lys-Val-Cys(1)-Thr-NH2; 3-(2-naphthyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide (2->7)-disulfide. CAS No. 108736-35-2. Pack Sizes: 25 mg. Product ID: BAT-010202. Molecular formula: C54H69N11O10S2. Mole weight: 1096.33. Custom synthesis is available. Send your inquiries for more information.
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L-Guanosine
L-Guanosine is a remarkable nucleoside widely utilized in exploring intricate neurological disorders, including Alzheimer's disease and dementia. Furthermore, L-Guanosine's pivotal role in RNA synthesis has propelled its prominence in the realm of antiviral drug development, specifically in the context of studying pernicious RNA viruses, such as hepatitis C. Group: Pharmaceutical. Alternative Names: Beta-L-ribo Guanosine; 9-(b-L-Ribofuranosyl)guanine; L-rG; 2-amino-9-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-β-L-ribofuranosyl-; 2-Amino-9-(β-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one; 2-Amino-1,9-dihydro-9-β-L-ribofuranosyl-6H-purin-6-one. CAS No. 26578-09-6. Pack Sizes: 10 mg. Product ID: B2706-014745. Molecular formula: C10H13N5O5. Mole weight: 283.24. Custom synthesis is available. Send your inquiries for more information.
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Lomeguatrib
Lomeguatrib, also known as PaTrin-2, is a potent Inhibitor of O6-Alkylguanine-DNA-Alkyltransferase. Lomeguatrib is also a nontoxic low-molecular weight pseudosubstrate that has the ability to inactivate MGMT. Lomeguatrib can be used with temozolomide (TMZ) for GBM treatment. Group: Pharmaceutical. Alternative Names: PaTrin 2; PaTrin2; PaTrin-2; Lomeguatrib; Patrin. O6-(4-bromothenyl)guanine; 6-(4-Bromothenyloxy)-7H-purin-2-amine. CAS No. 192441-08-0. Pack Sizes: 100 mg. Product ID: B0084-086622. Molecular formula: C10H8BrN5OS. Mole weight: 326.172. Custom synthesis is available. Send your inquiries for more information.
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Treosulfan
Treosulfan is the prodrug of a bifunctional sulfonate alkylating agent with myeloablative, immunosuppresive, and antineoplastic activities. Under physiological conditions, treosulfan converts nonenzymatically to L-diepoxybutane via a monoepoxide intermediate. The monoepoxide intermediate and L-diepoxybutane alkylate DNA at guanine residues and produce DNA interstrand crosslinks, resulting in DNA fragmentation and apoptosis. In escalated doses, this agent also exhbits myeloablative and immunosuppressive activities. Group: Pharmaceutical. Alternative Names: NSC 39069; NSC39069; NSC-39069; Treosulfan; (2S,3S)-2,3-Dihydroxybutane-1,4-diyl dimethanesulfonate. CAS No. 299-75-2. Pack Sizes: 25 mg. Product ID: B2693-065470. Molecular formula: C6H14O8S2. Mole weight: 278.29. Custom synthesis is available. Send your inquiries for more information.
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O-[(Guanin-7-yl)methyl] Acyclovir
An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Group: Pharmaceutical. Alternative Names: 2-amino-7-((2-((2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)ethoxy)methyl)-1,7-dihydro-6H-purin-6-one. CAS No. 1797832-75-7. Pack Sizes: 5 mg. Product ID: B0093-466139. Molecular formula: C14H16N10O4. Mole weight: 388.35. Custom synthesis is available. Send your inquiries for more information.
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