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| Product | Description | |
|---|---|---|
| GSK-923295 | GSK-923295 is a novel antimitotic inhibitor of centromere-associated protein E (CENP-E) with potential anticancer activity. GSK-923295 demonstrated significant antitumor activity against solid tumor models, inducing CRs in Ewing sarcoma, rhabdoid, and rhabdomyosarcoma xenografts. Clinical study showed that GSK-923295 had dose-proportional pharmacokinetics and a low number of grade 3 or 4 adverse events. The observed incidence of myelosuppression and neuropathy was low. Further investigations may provide a more complete understanding of the potential for GSK-923295 as an antiproliferative agent. Group: Pharmaceutical. Alternative Names: GSK923295; GSK 923295; GSK-923295; GSK-923295A; GSK923295A; GSK 923295A. CAS No. 1088965-37-0. Pack Sizes: 100 mg. Product ID: B1370-456847. Molecular formula: C32H38ClN5O4. Mole weight: 592.14. Custom synthesis is available. Send your inquiries for more information. |  London |
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