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| Product | Description | |
|---|---|---|
| GNE-8525 | This active molecular is a selective pan-TRK inhibitor. GNE-8525 shows potent antiproliferation activity (IC50 = 0.003 μM) and it shows in vivo antitumor efficacy in tumor xenograft model derived from the KM12 cell line. TRKA are believed to be the key oncogenic driver in many tumors including glioblastoma, melanoma and so on. Uses: Antitumor. Group: Pharmaceutical. Alternative Names: GNF-8625; GNF 8625; GNF8625. (R)-1-(6-(6-(2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazin-3-yl)-[2,4'-bipyridin]-2'-yl)piperidin-4-ol. CAS No. 1196546-33-4. Pack Sizes: 50 mg. Product ID: B0084-475140. Molecular formula: C31H30FN7O. Mole weight: 535.63. Custom synthesis is available. Send your inquiries for more information. |  London |
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