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Glutathione (GSH) is an endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione may decrease the concentrations of inflammatory cytokines (IL-6, IL-18), and neutrophils in lung tissue, increase the level of serum Ca2+, and be useful for the treatment of ANP. Glutathione can be used not only as medicine but also as a base material for functional foods. It is widely used in functional foods for delaying aging, enhancing immunity, and anti-tumor. Glutathione is the main ingredient in ''whitening needle'' injections, and it is also the main ingredient in many beauty products on the market. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 70-18-8. Pack Sizes: 100 g. Product ID: BAT-010793. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Glutathione EP Impurity C
Oxiglutatione is a stabilized formulation of disodium glutathione disulfide (GSSG; oxidized glutathione) and cisplatin (1000:1) with potential chemoprotective and immunomodulating activities. Mimicking endogenous GSSG, Oxiglutatione acts as a competitive substrate for gamma-glutamyl-transpeptidase (GGT), which may result in the S-glutathionylation of proteins, predominantly actin, a redox stress on endoplasmic reticulum (ER), and ER stress-induced apoptosis. S-glutathionylation may be stimulated by reactive oxygen species (ROS) liberated by an oxiglutatione-induced increase in GGT activity. Oxiglutatione may also induce phosphorylation of proteins such as ERK and p38, two kinases that play critical regulatory roles in cell proliferation and apoptosis. The cisplatin component of this agent does not provide an effective therapeutic concentration of cisplatin in vivo. Group: Pharmaceutical. CAS No. 27025-41-8. Pack Sizes: 25 g. Product ID: B0084-064728. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Glutathione EP Impurity D
Glutathione EP Impurity D is a substrate used for the biosynthesis of L-glutathione by glutathione synthetase. It is used to study the active sites and kinetics of glutathione synthestase(s). It is also used in biological studies for the detection of thiols. Group: Pharmaceutical. CAS No. 636-58-8. Pack Sizes: 1 g. Product ID: BAT-015930. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Glutathione Impurities
Glutathione Impurities, integral to biomedical endeavors, serve as reference standards in quality control during drug formulation and production. Their pivotal role ensures therapeutic agents' purity and safety against oxidative stress-related ailments, such as Parkinson's and Alzheimer's, while also fostering progress in detoxification science and antioxidant intervention strategies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Glutathione reduced
25g Pack Size. Group: Analytical Reagents, Bioactive Small Molecules, Biochemicals, Flavours and Fragrance Materials. Formula: C10H17N3O6S. CAS No. 70-18-8. Prepack ID : 14457031-25g. Molecular Weight : 307.32.
Glutathione reduced
5g Pack Size. Group: Analytical Reagents, Bioactive Small Molecules, Biochemicals, Flavours and Fragrance Materials. Formula: C10H17N3O6S. CAS No. 70-18-8. Prepack ID : 14457031-5g. Molecular Weight : 307.32.
Glutathione reduced (Food Grade)
25g Pack Size. Group: Amino Acids, Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials, Organics. Formula: C H N O S. CAS No. 70-18-8. Prepack ID : 90022825-25g. Molecular Weight : 307.32.
Glutathione reduced (Food Grade)
5g Pack Size. Group: Amino Acids, Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials, Organics. Formula: C H N O S. CAS No. 70-18-8. Prepack ID : 90022825-5g. Molecular Weight : 307.32.
Glutathione reduced (Pharma Grade)
5g Pack Size. Group: Peptide Reagents, Research Organics & Inorganics. Formula: C10H17N3O6S. CAS No. 70-18-8. Prepack ID : 90028965-5g. Molecular Weight : 307.32.
Glutathionesulfonic acid
Glutathionesulfonic acid is a metabolite of glutathione. Group: Pharmaceutical. CAS No. 3773-7-7. Pack Sizes: 100 mg. Product ID: BAT-010743. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Glutathione USP
Glutathione USP. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 70-18-8. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications.
Cenik Chemicals
L-Glutathione oxidised
25g Pack Size. Group: Biochemicals. Formula: C20H32N6O12S2. CAS No. 27025-41-8. Prepack ID : 37908488-25g. Molecular Weight : 612.63.
L-Glutathione oxidised
5g Pack Size. Group: Biochemicals. Formula: C20H32N6O12S2. CAS No. 27025-41-8. Prepack ID : 37908488-5g. Molecular Weight : 612.63.
L-Glutathione oxidized disodium salt
100mg Pack Size. Group: Biochemicals, Peptide Reagents. Formula: C20H30N6Na2O12S2. CAS No. 103239-24-3. Prepack ID : 10224193-100mg. Molecular Weight : 656.59.
S-acetylglutathione
S-acetylglutathione is a glutathione derivative that has been shown to inhibit the replication of herpes simplex virus 1 (HSV-1) in human foreskin fibroblasts when used at concentrations of 5 and 10 mM. Group: Pharmaceutical. CAS No. 3054-47-5. Pack Sizes: 100 g. Product ID: B2693-397431. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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(1S,3R)-RSL3
(1S,3R)-RSL3 is a glutathione peroxidase 4 (GPX4) inhibitor with EC50 of 10 μM in cellular assay. It binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis. Group: Pharmaceutical. CAS No. 1219810-16-8. Pack Sizes: 100 mg. Product ID: B0084-474402. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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ADT-OH
ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. ADT is a putative neuroprotectant and antioxidant that increases glutathione levels in cultured astroglial cells. ADT-OH was shown to reduce tPA-enhanced Akt activation and VEGF expression in brain microvascular endothelial cells. Group: Pharmaceutical. CAS No. 18274-81-2. Pack Sizes: 50 mg. Product ID: B0084-284826. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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CORM-3
CORM-3 is a water-soluble carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity. It attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels. Group: Pharmaceutical. CAS No. 475473-26-8. Pack Sizes: 50 mg. Product ID: B0084-463459. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Ebselen
Ebselen, also known as SPI-1005, is an organoselenium compound with potential anti-oxidant, anti-inflammatory and cytoprotective activity. Upon oral administration of SPI-1005, this agent mimics the activity of glutathione peroxidase (GPx) and can utilize glutathione to reduce other unstable molecules, thus preventing the formation of reactive oxygen species (ROS) and reducing oxidative stress on the cell. In the cochlea, this agent may prevent drug-induced injury to the auditory hair cells thereby preventing hearing loss. GPx is the main antioxidant enzyme in the cochlea and protects the inner ear from loud sounds and biochemical damage. In addition, ebselen is able to inhibit the activity of many enzymes involved in inflammation. Group: Pharmaceutical. CAS No. 60940-34-3. Pack Sizes: 1 g. Product ID: B2693-072972. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Eriocitrin
Eriocitrin is a powerful antioxidative flavonoid in lemon with lipid-lowering effects in a rat model of high-fat diet. It might play an important role in the control of the change in glutathione redox status in rat liver during exercise. These findings showed that Eriocitrin was effective in the prevention of oxidative damages caused by acute exercise-induced oxidative stress. Eriocitrin was suggested to be metabolized by intestinal bacteria, and then eriodictyol and 3,4-dihydroxyhydrocinnamic of its metabolite were absorbed. Following administration of Eriocitrin, plasma exhibited an elevated resistance effect to lipid peroxidation. Eriocitrin metabolites functioning as antioxidant agents are discussed. Uses: Antioxidant. Group: Pharmaceutical. CAS No. 13463-28-0. Pack Sizes: 25 mg. Product ID: B2703-465065. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Ezatiostat
Ezatiostat is a glutathione analog that acts as an inhibitor of glutathione S-transferase (GST) P1-1. TLK117, the active form of ezatiostat, inhibits GSTP1-1, resulting in phosphorylation of JNK, restoring JNK-mediated cellular proliferation and differentiation signaling pathways. Group: Pharmaceutical. CAS No. 168682-53-9. Pack Sizes: 25 mg. Product ID: BAT-010079. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Ginsenoside Rd2
Ginsenoside Rd2 is a composition of roots of Panax ginseng. Ginsenoside Rd is a primary constituent of the ginseng rhizome and the administration of ginsenoside Rd significantly increased the reduced GSHPx and glutathione reductase activity. Group: Pharmaceutical. CAS No. 83480-64-2. Pack Sizes: 10 mg. Product ID: B0005-479871. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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LCS3
LCS3 is a reversible inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50 of 3.3 μM and 3.8 μM, respectively. Group: Pharmaceutical. CAS No. 109844-92-0. Pack Sizes: 50 mg. Product ID: B1370-185021. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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N-Acetyl-L-cysteine
N-Acetyl-L-cysteine is an antioxidant and precursor to glutathione. It has potential anticancer activity against tumor cell growth. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 616-91-1. Pack Sizes: 250 g. Product ID: BAT-008075. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Pimonidazole
Pimonidazole, also known as Ro 03-8799 and PD 126675, is a nitroimidazole drug with hypoxic selectivity and radiosensitizing property. Pimonidazole is reduced in hypoxic environments as in tumor cells, thereby it can be used as an hypoxia marker. In hypoxic cells, reduced pimonidazole binds to -SH-containing molecules such as glutathione and proteins, and the resulting complexes accumulated in tissues, thereby sensitizing cells to be more susceptible for radiation treatment. Group: Pharmaceutical. CAS No. 70132-50-2. Pack Sizes: 100 mg. Product ID: B1370-181685. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Protein hydrolyzates, yeast
Protein hydrolyzates, yeast is a hydrolyzed product of yeast cells, which is obtained by autolysis or hydrolysis with additional enzymes. Hydrolyzed yeast products contain a large number of amino acids, small peptides, rich B vitamins, glutathione and nucleotide substances. It is mainly used as an antioxidant in cosmetics and skin care products, controlling oil and resisting fat overflow. Group: Pharmaceutical. CAS No. 100684-36-4. Pack Sizes: 1 g. Product ID: B0001-052866. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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RTA-408
RTA-408 is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity. Upon administration, RTA 408 activates the cytoprotective transcription factor Nrf2. In turn, Nrf2 translocates to the nucleus, dimerizes with a small Maf protein (sMaf), and binds to the antioxidant response element (ARE). This induces the expression of a number of cytoprotective genes, including NAD(P)H quinone oxidoreductase 1 (NQO1), sulfiredoxin 1 (Srxn1), heme oxygenase-1 (HO1, HMOX1), superoxide dismutase 1 (SOD1), gamma-glutamylcysteine synthetase (gamma-GCS), thioredoxin reductase-1 (TXNRD1), glutathione S-transferase (GST), glutamate-cysteine ligase catalytic subunit (Gclc) and glutamate-cysteine ligase regulatory subunit (Gclm), and increases the synthesis of the antioxidant glutathione (GSH). Nrf2, a leucine zipper transcription factor, plays a key role in the maintenance of redox balance and cytoprotection against oxidative stress. Group: Pharmaceutical. CAS No. 1474034-05-3. Pack Sizes: 20 mg. Product ID: B0084-462776. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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S107
S107 is a type 1 ryanodine receptor (RyR1) stabilizer that binds RyR1 and enhances the binding affinity of calstabin-1. S107 increased FKBP12 binding to RyR1 in SR vesicles in the presence of reduced glutathione and the NO-donor NOC12, with no effect in the presence of oxidized glutathione. Group: Pharmaceutical. CAS No. 927871-76-9. Pack Sizes: 50 mg. Product ID: B0084-007820. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Sedanolide
Sedanolide is a natural phthalide compound originally isolated from seed oil of the Umbelliferae family, including celery. It is an inducer of glutathione S-transferase and inhibitor of chemically induced carcinogenesis. Group: Pharmaceutical. CAS No. 6415-59-4. Pack Sizes: 10 mg. Product ID: B1370-130717. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Sulforaphane
Sulforaphaneis a naturally-occurring phytochemical belonging to the class of isothiocyanates. As the aglycone metabolite of glucosinolate glucoraphanin (sulforaphane glucosinolate), sulforaphane acts as an antioxidant and potent stimulator of endogenous detoxifying enzymes. This agent displays anticarcinogenic properties due to its ability to induce phase II detoxification enzymes, such as glutathione S-transferase and quinone reductase, thereby providing protection against certain carcinogens and toxic, reactive oxygen species. Broccoli sprouts contain large amounts of sulforaphane, which is also found in other cruciferous vegetables including cabbage and kale. Uses: Anti-inflammatory/antitumor. Group: Pharmaceutical. CAS No. 4478-93-7. Pack Sizes: 1 g. Product ID: NP4355. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Taraxerone
Taraxerone is isolated from the herb of Taraxacum mongolicum Hand. Mazz. It can prevent catalase and superoxide dismutase, and reduce glutathione concentration. Group: Pharmaceutical. CAS No. 514-07-8. Pack Sizes: 20 mg. Product ID: NP6262. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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