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foretinib Potent inhibitor of MET, VEGFR2, Ron and AXL (IC50 values are 0.4, 0.9, 3 and 11 nM, respectively). Also potently inhibits Tie-2, Flt-1, Flt-3, Flt-4, KIT, PDGFRalpha and PDGFRbeta. Inhibits migration and invasion of B16F10 melanoma cells in vitro. Suppresses B16F10 tumor growth and metastasis in mice. Group: Pharmaceutical. Alternative Names: XL880; XL 880; XL-880; GSK1363089; GSK 1363089; GSK-1363089; GSK089; EXEL2880; Foretinib. CAS No. 849217-64-7. Pack Sizes: 250 mg. Product ID: B2693-152657. Molecular formula: C34H34F2N4O6. Mole weight: 632.665. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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