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2-Bromo-1-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)ethanone, a promising small molecule inhibitor, holds tremendous potential for use in biomedical research towards terminal selectivity of enzymes or pathologies. Nevertheless, the paucity of available information concerning this compound hampers its functional applications in diverse biological contexts. Group: Pharmaceutical. Alternative Names: Ethanone, 2-bromo-1-[3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl]-; 2-Bromo-1-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)ethan-1-one. CAS No. 1056050-24-8. Pack Sizes: 500 mg. Product ID: B2699-128594. Molecular formula: C12H10BrFN2O. Mole weight: 297.12. Custom synthesis is available. Send your inquiries for more information.
An impurity of safinamide, which is a selective monoamine oxidase B inhibitor reducing degradation of dopamine. Group: Pharmaceutical. Alternative Names: Safinamide Impurity 4; (R)-N2-{4-[(3-fluorobenzyl)oxy]benzyl}alaninamide. CAS No. 174756-44-6. Pack Sizes: 1 mg. Product ID: B1605-458661. Molecular formula: C17H19FN2O2. Mole weight: 302.349. Custom synthesis is available. Send your inquiries for more information.
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4-(2-Fluoro-4-nitrophenyl)morpholine
4-(2-Fluoro-4-nitrophenyl)morpholine. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 2689-39-6. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. Categories: 2 4-(2-fluoro-4-nitro-phenyl)-morpholine.
6-(Benzyloxy)-4-(3-chloro-4-fluorophenylamino)-7-methoxy-quinazoline (CAS# 913819-12-2 ) is a useful research chemical. Group: Pharmaceutical. Alternative Names: N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(phenylmethoxy)-4-quinazolinamine. CAS No. 913819-12-2. Pack Sizes: 1 g. Product ID: B2699-100471. Molecular formula: C22H17ClFN3O2. Mole weight: 409.84. Custom synthesis is available. Send your inquiries for more information.
A useful composition for treating or preventing dry eye disorders. Group: Pharmaceutical. Alternative Names: JAK-IN-10; 916741-98-5; 5-[[5-fluoro-4-(4-prop-2-ynoxyanilino)pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide; SCHEMBL1275642HY-U00277. CAS No. 916741-98-5. Pack Sizes: 1mg;1g;10g. Product ID: 916741-98-5. Molecular formula: C20H18FN5O3S. Mole weight: 427.45. Custom synthesis is available. Send your inquiries for more information.
A metabolite of Aprepitant. Group: Pharmaceutical. Alternative Names: Monobenzyl Fosaprepitant. CAS No. 889852-02-2. Pack Sizes: 1mg;1g;10g. Product ID: NP3713. Molecular formula: C30H28F7N4O6P. Mole weight: 704.54. Custom synthesis is available. Send your inquiries for more information.
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Bis(4-fluorophenyl)phenylphosphine oxide
Catalyst for hydroformylation reactions Used for preparation of chlorine-tolerant polymers for desalination Crosslinking agent in preparation of polymer electrolyte membranes for fuel cell applications. Group: Pharmaceutical. Alternative Names: Bis(4-fluorophenyl)phenylphosphineoxide. CAS No. 54300-32-2. Pack Sizes: 5 g. Product ID: B2699-026488. Molecular formula: C18H13F2OP. Mole weight: 314.27. Custom synthesis is available. Send your inquiries for more information.
6-Iodo-N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]quinazolin-4-amine is a chemical compound employed in the synthesis of novel anticancer agents that selectively modulate pivotal signaling cascades crucial for malignant cell growth and viability, exhibiting notable efficacy against diverse malignancies such as lung carcinoma and breast adenocarcinoma. Group: Pharmaceutical. CAS No. 231278-20-9. Pack Sizes: 1mg;1g;10g. Product ID: NP3186. Molecular formula: C21H14ClFIN3O. Mole weight: 505.71. Custom synthesis is available. Send your inquiries for more information.
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(1R,2R,3R)-Aprepitant
An isomer of Aprepitant, a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. Group: Pharmaceutical. Alternative Names: (R,R,R)-Aprepitant; USP Aprepitant Related Compound A; Aprepitant Related Compound A; Aprepitant USP Related Compound A; Aprepitant R,R,R-Diastereomer; 3-[[(2R,3R)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholino]methyl]-1H-1,2,4-triazol-5(4H)-one; 5-[[(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Aprepitant USP RC A (R,R,R-Diasteromer). CAS No. 1148113-53-4. Pack Sizes: 50 mg. Product ID: B2694-466699. Molecular formula: C23H21F7N4O3. Mole weight: 534.44. Custom synthesis is available. Send your inquiries for more information.
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(1R,2S,3R)-Aprepitant
An isomer of Aprepitant, a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. Group: Pharmaceutical. Alternative Names: 5-(((2S,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-3(2H)-one. CAS No. 1185502-97-9. Pack Sizes: 50 mg. Product ID: B2694-466697. Molecular formula: C23H21F7N4O3. Mole weight: 534.44. Custom synthesis is available. Send your inquiries for more information.
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(1R,2S,3S)-Aprepitant
An isomer of Aprepitant, a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. Group: Pharmaceutical. Alternative Names: 5-(((2S,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-3(2H)-one. CAS No. 172822-28-5. Pack Sizes: 50 mg. Product ID: B2694-466702. Molecular formula: C23H21F7N4O3. Mole weight: 534.44. Custom synthesis is available. Send your inquiries for more information.
London
(1S,2R,3R)-Aprepitant
An isomer of Aprepitant, a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. Group: Pharmaceutical. Alternative Names: 5-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-3(2H)-one. CAS No. 1242175-34-3. Pack Sizes: 50 mg. Product ID: B2694-466696. Molecular formula: C23H21F7N4O3. Mole weight: 534.44. Custom synthesis is available. Send your inquiries for more information.
London
(1S,2S,3S)-Aprepitant
An isomer of Aprepitant, a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. Group: Pharmaceutical. Alternative Names: 5-(((2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-3(2H)-one. CAS No. 1242175-40-1. Pack Sizes: 100 mg. Product ID: B2694-466704. Molecular formula: C23H21F7N4O3. Mole weight: 534.44. Custom synthesis is available. Send your inquiries for more information.
London
2-Amino-2'-fluorobenzophenone
An intermediate in the synthesis of Pitavastatin, a HMG-CoA reductase inhibitor that lowers LDL cholesterol and triglycerides and increase HDL cholesterol in your blood. Group: Pharmaceutical. Alternative Names: 2-Amino-2'-fluoro-benzophenone; (2-Amino-phenyl)-(2-fluoro-phenyl)-methanone. CAS No. 1581-13-1. Pack Sizes: 1 g. Product ID: B2694-010195. Molecular formula: C13H10FNO. Mole weight: 215.22. Custom synthesis is available. Send your inquiries for more information.
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2-Amino-4'-fluorobenzophenone
2-Amino-4'-fluorobenzophenone is an intermediate in the preparation of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Uses: An intermediate in the preparation of the anticholesteremic pitavastatin. Group: Pharmaceutical. Alternative Names: 2-Aminophenyl 4-Fluorophenyl Ketone; o-(p-Fluorobenzoyl)aniline; (2-Amino-4'-fluoro-phenyl)-phenyl-methanone; 2-Amino-4'-fluorobenzophenone. CAS No. 3800-6-4. Pack Sizes: 1mg;1g;10g. Product ID: NP3451. Molecular formula: C13H10FNO. Mole weight: 215.22. Custom synthesis is available. Send your inquiries for more information.
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2-Flurbiprofen
Flurizan, also called Tarenflurbil, is a nonsteroidal anti-inflammatory drug which inhibits γ-secretase activity leading to preventing the formation of the amyloid β peptide (Aβ42) from amyloid β precursor protein (APP). Uses: (r)-2-flurbiprofen is the r-isomer of flurbiprofen (f598700), an anti-inflammatory used as an analgesic. Group: Pharmaceutical. Alternative Names: (2R)-2-(3-fluoro-4-phenylphenyl)propanoic acid. CAS No. 51543-40-9. Pack Sizes: 1mg;1g;10g. Product ID: NP3244. Molecular formula: C15H13FO2. Mole weight: 244.26. Custom synthesis is available. Send your inquiries for more information.
London
3-Fluoro-4-morpholinoaniline
3-Fluoro-4-morpholinoaniline. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 93246-53-8. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. Categories: 93 3-fluoro-4-morpholin-4-yl-phenylamine.
Cenik Chemicals
(3R)-Atorvastatin Cyclic Calcuim Salt (Isopropyl) Impurity
An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Group: Pharmaceutical. Alternative Names: Atorvastatin Cyclic Calcium Salt (Isopropyl) Impurity; (3R)-4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H-pyrrolo[2,1-b][1,3]oxazin-2-yl}-3-hydroxybutanoic acid calcium salt; Atorvastatin Cyclic Isopropyl Impurity; Atorvastatin Cyclic 6-Hydroxy Impurity. Pack Sizes: 2.5 mg. Product ID: B1370-448092. Molecular formula: C66H68CaF2N4O14. Mole weight: 1219.36. Custom synthesis is available. Send your inquiries for more information.
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(3'S,3R,4S)-Desfluoro Ezetimibe
An stereoisomer of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L9) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-phenylpropyl]-2-azetidinone. CAS No. 190595-66-5. Pack Sizes: 10 mg. Product ID: B2694-471389. Molecular formula: C24H22FNO3. Mole weight: 391.45. Custom synthesis is available. Send your inquiries for more information.
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(3S,5S)-Atorvastatin Acetonide tert-Butyl Ester
(3S,5S)-Atorvastatin Acetonide tert-Butyl Ester is a pharmaceutical compound employed in managing hyperlipidemia and cardiovascular disorders. It is a modified form of atorvastatin, acting as a potent HMG-CoA reductase inhibitor to mitigate cholesterol biosynthesis within hepatic cells. This medication plays a pivotal role in ameliorating lipid profiles and averting atherosclerosis progression. Uses: An intermediate for the preparation of (3s,5s)-atorvastatin. Group: Pharmaceutical. Alternative Names: (4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. CAS No. 472967-95-6. Pack Sizes: 25 mg. Product ID: B2692-117415. Molecular formula: C40H47FN2O5. Mole weight: 654.81. Custom synthesis is available. Send your inquiries for more information.
London
4-Fluoro-3-(morpholin-4-yl)aniline
An impurity of Linezolid, an antibiotic against Gram-positive bacteria. Group: Pharmaceutical. Alternative Names: 4-fluoro-3-(morpholin-4-yl)aniline; 1175797-88-2; 4-fluoro-3-morpholin-4-ylaniline; SCHEMBL520787; BEZHNTGNWHZZPE-UHFFFAOYSA-N; AXB79788; AKOS022258274; 4-Fluoro-3-morpholin-4-yl-phenylamine; CS-0245733; EN300-310122; Z1255400162. CAS No. 1175797-88-2. Pack Sizes: 100 mg. Product ID: B0073-284950. Molecular formula: C10H13FN2O. Mole weight: 196.225. Custom synthesis is available. Send your inquiries for more information.
London
5-Methyl-2'-Fluoro-U Phosphoramidite
5-Methyl-2'-Fluoro-U Phosphoramidite, a pivotal compound with paramount significance in the domain of biomedicine, assumes the role of a fundamental constituent within the intricate framework of synthesized nucleic acids. Its exceptional utility lies in its indispensable contribution to the progressive advancement of antisense oligonucleotide development. Notably, this phosphoramidite possesses an intrinsic capacity to effectively combat a myriad of ailments encompassing viral infections and genetic disorders, by selectively targeting specified genes or RNA sequences. Group: Pharmaceutical. Alternative Names: 5-Me-5'-O-DMT-2'-fluoro-2'-Deoxyuridine 3'-CE phosphoramidite; 2'-F T amidite; 2'-Fluoro-dT Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-5-methyluridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 2'-Fluoro-5MeU-3'-phosphoramidite; DMTr-2'-F-dT-3'-CE-Phosphoramidite; DMT-5-Me-2'-F-dU-CE-Phosphoramidite. CAS No. 182700-06-7. Pack Sizes: 5 g. Product ID: B1370-288524. Molecular formula: C40H48FN4O8P. Mole weight: 762.82. Custom synthesis is available. Send your inquiries for more information.
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a modified phosphoramidite designed for use in the synthesis of stable and efficient RNA and DNA oligonucleotides. Its protective groups and modifications enhance the stability of the resulting nucleic acids and facilitate their incorporation into nucleic acid chains during solid-phase synthesis. This compound is crucial in the production of antisense oligonucleotides, siRNA, probes, and primers, providing enhanced resistance to enzymatic degradation and improved performance in various applications. Group: Pharmaceutical. Alternative Names: 2'-F-dU Phosphoramidite; DMT-2'Fluoro-dU Phosphoramidite; 5'-O-Dimethoxytrityl-2'-fluoro-2'-deoxyuridine 3'-CE phosphoramidite; 2'-Deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-fluorouridine 3-CE phosphoramidite; DMT-2'-Fluoro-dU amidite; 2'-Fluoro-2'-deoxy Uridine CED Phosphoramidite; 2'-Deoxy-5'-O-DMT-2'-fluorouridine 3-CE phosphoramidite; 5'-O-DMT-2'-F-dU 3'-CE phosphoramidite. CAS No. 146954-75-8. Pack Sizes: 5 g. Product ID: B2706-084339. Molecular formula: C39H46FN4O8P. Mole weight: 748.78. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-2'-Fluoro-N2-isobutyryl-2'-Deoxy-guanosine 3'-CE phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It features a 5'-dimethoxytrityl (DMT) protecting group at the 5'-hydroxyl position, a 2'-fluoro modification to enhance stability and binding affinity, an N2-isobutyryl group protecting the exocyclic amine of the guanine base, and a cyanoethyl (CE) group on the 3'-phosphoramidite. These modifications make it suitable for synthesizing oligonucleotides with improved resistance to enzymatic degradation and enhanced hybridization properties, which are crucial for applications in research, diagnostics, and therapeutics. Group: Pharmaceutical. Alternative Names: 2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine 3'-CE phosphoramidite; 2'-F-iBu-G-CEP; 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)?-Guanosine 3'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]; DMT-2'Fluoro-dG(iBu) Phosphoramidite; 2'-F-dG(iBu) 3'-CE phosphoramidite; DMT-2'-F-dG(iBu)-CE Phosphoramidite; 2'-F-dG(iBu)-CE Phosphoramidite; 2'-Fluoro-N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine-3'-CE-Phosphoramidite. CAS No. 144089-97-4. Pack Sizes: 5 g. Product ID: B2706-291975. Molecular formula: C44H53FN7O8P. Mole weight: 857.91. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-5-Fluoro-2'-deoxyuridine-3'-CE Phosphoramidite is a highly potent reagent for the synthesis of 5-fluorouracil (5-FU) containing oligonucleotides, with potential applications in the treatment of cancer. By boosting the selectivity and efficacy of 5-FU, a well-established chemotherapy drug for different forms of cancer, this compound constitutes a promising avenue to enhance the therapeutic options available to patients. Group: Pharmaceutical. Alternative Names: 5-F-dU Phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-uridine 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; FdU-amidite; NSC-729744. CAS No. 142246-63-7. Pack Sizes: 250 mg. Product ID: B2706-049657. Molecular formula: C39H46FN4O8P. Mole weight: 748.78. Custom synthesis is available. Send your inquiries for more information.
London
5'-O-DMT-N4-benzoyl-2'-fluoro-2'-deoxycytidine
5'-O-DMT-N4-benzoyl-2'-fluoro-2'-deoxycytidine boasts a promising pharmacological arsenal to combat a range of viral infections. With virucidal efficacy that targets the DNA replication machinery of several virus strains, the drug holds considerable therapeutic potential for cases of hepatitis B and C, as well as herpes and shingles. Furthermore, its anti-neoplastic properties make it a noteworthy exploratory tool for certain types of cancer treatment. Group: Pharmaceutical. Alternative Names: 5'-O-(4,4'-dimethoxytrityl)-N4-benzoyl-2'-fluoro-2'-deoxycytidine; N4-Bz-DMT-2'-F-dC; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-D-cytidine; N4-Benzoyl-5'-O-DMT-2'-fluoro-2'-deoxycytidine; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine; 5'-O-DMTr-2'-F-dC(Bz); 5'-DMT-2'-F-Bz-dC; 5'-O-(4,4'-dimethoxytrityl)-N6-Benzoyl-2'-fluoro-2'-deoxyadenosine; N-{1-{5-O-[bis-(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-D-arabinofuranosyl}-1,2-dihydro-2-oxo-4-pyrimidinyl}-benzamide; N-benzoyl-5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-deoxy-2'-fluoro-Cytidine; 5'-O-DMT-N4-Bz-2'-F-dC. CAS No. 146954-77-0. Pack Sizes: 5 g. Product ID: B1370-376765. Molecular formula: C37H34FN3O7. Mole weight: 651.68. Custom synthesis is available. Send your inquiries for more information.
London
6-FAM-DMT-phosphoramidite
6-FAM-DMT Phosphoramidite is a phosphoramidite derivative used to introduce 6-carboxyfluorescein (6-FAM) into oligonucleotides during solid-phase synthesis. It includes a 6-FAM fluorophore and a dimethoxytrityl (DMT) protecting group, which facilitates efficient incorporation and subsequent deprotection during synthesis. This reagent enables the production of fluorescently labeled oligonucleotides for applications such as fluorescence-based detection, quantitative PCR (qPCR), and fluorescence resonance energy transfer (FRET) assays. Group: Pharmaceutical. Alternative Names: 6-Fluorescein Phosphoramidite; 2-Dimethoxytrityloxymethyl-6-(3',6'-dipivaloylfluorescein-6-yl-carboxamido)-hexyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-6-Fluorescein phosphoramidite (with DMT); Propanoic acid, 2,2-dimethyl-, 6-[7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl ester; DMT-6-FAM phosphoramidite. CAS No. 316121-60-5. Pack Sizes: 250 mg. Product ID: B1370-070723. Molecular formula: C68H78N3O13P. Mole weight: 1176.33. Custom synthesis is available. Send your inquiries for more information.
London
A1B1 hydrochloride
A1B1 hydrochloride is a potent and orally-available chemokine CCR1 antagonist. Group: Pharmaceutical. Alternative Names: N-[5-chloro-2-[(E)-3-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-3-oxoprop-1-enyl]phenyl]acetamide hydrochloride. Pack Sizes: 1mg;1g;10g. Molecular formula: C23H25ClFN3O2.HCl. Mole weight: 466.38. Custom synthesis is available. Send your inquiries for more information.
London
A-395
A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions, and can effectively inhibit the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM. Group: Pharmaceutical. Alternative Names: 3-Pyrrolidinamine, 1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-[4-[4-(methylsulfonyl)-1-piperazinyl]phenyl]-, (3R,4S)-; (3R,4S)-1-(7-Fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-{4-[4-(methylsulfonyl)-1-piperazinyl]phenyl}-3-pyrrolidinamine. CAS No. 2089148-72-9. Pack Sizes: 1mg;1g;10g. Product ID: 2089148-72-9. Molecular formula: C26H35FN4O2S. Mole weight: 486.65. Custom synthesis is available. Send your inquiries for more information.
London
ABBV-744
ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2, BRD3 and BRD4. It is developed for treating AML and cancers. Group: Pharmaceutical. Alternative Names: N-ethyl-4-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide. CAS No. 2138861-99-9. Pack Sizes: 1mg;1g;10g. Product ID: 2138861-99-9. Molecular formula: C28H30FN3O4. Mole weight: 491.55. Custom synthesis is available. Send your inquiries for more information.
London
Afatinib Impurity 52
Afatinib Impurity 52 is an impurity of Afatinib, a drug used to treat non-small cell lung cancer (NSCLC). Group: Pharmaceutical. Alternative Names: (S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate; Diethyl {[4-(3-Chloro-4-Fluoro-Phenylamino)-7-((S)-Tetrahydrofuran-3-Yloxy)-Quinazolin-6-Ylcarbamoyl]-Methyl}-Phosphonate. CAS No. 618061-76-0. Pack Sizes: 100 mg. Product ID: B2699-424124. Molecular formula: C24H27ClFN4O6P. Mole weight: 552.92. Custom synthesis is available. Send your inquiries for more information.
London
Aprepitant
Aprepitant is a specific NK-1R antagonist, used as an antiemetic agent. Group: Pharmaceutical. Alternative Names: 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Emend; L 754030; MK 0869; MK 869; ONO 7436. CAS No. 170729-80-3. Pack Sizes: 1 g. Product ID: B2692-461949. Molecular formula: C23H21F7N4O3. Mole weight: 534.43. Custom synthesis is available. Send your inquiries for more information.
London
ARQ-087
ARQ-087, also known as Derazantinib, is an oral fibroblast growth factor receptor (FGFR) inhibitor with antitumor property. FGFR plays a role in the regulation of key cellular behaviors including proliferation, cell differentiation and so on. FGFR dysregulation is considered as a driver in multiple cancers. ARQ 087 binds to FGFR and effectively inhibits the activation of FGFR thus can suppress tumorigenesis and tumor growth. Group: Pharmaceutical. Alternative Names: ARQ 087; ARQ087; ARQ-087; Derazantinib; (6R)-6-(2-fluorophenyl)-N-[3-[2-(2-methoxyethylamino)ethyl]phenyl]-5,6-dihydrobenzo[h]quinazolin-2-amine. CAS No. 1234356-69-4. Pack Sizes: 5 mg. Product ID: B0084-008116. Molecular formula: C29H29FN4O. Mole weight: 468.576. Custom synthesis is available. Send your inquiries for more information.
An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Group: Pharmaceutical. Alternative Names: (2E)-2,3-Dehydroxy Atorvastatin calcium; (2E,5S)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-5-hydroxy-2-heptenoic Acid calcium salt. Pack Sizes: 2 mg. Product ID: B2694-466961. Molecular formula: C66H64F2N4O8Ca. Mole weight: 1119.33. Custom synthesis is available. Send your inquiries for more information.
London
Atorvastatin calcium trihydrate
Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. Uses: An inhibitor of hmg-coa reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. Group: Pharmaceutical. Alternative Names: CI-981; CI 981; CI981; calcium bis{(3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate} trihydrate. CAS No. 344423-98-9. Pack Sizes: 10 g. Product ID: B1370-241758. Molecular formula: C66H74CaF2N4O13. Mole weight: 1209.4. Custom synthesis is available. Send your inquiries for more information.
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Atorvastatin Cyclic Isopropyl Impurity
Atorvastatin Cyclic Isopropyl Impurity is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Group: Pharmaceutical. Alternative Names: 4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H-pyrrolo[2,1-b][1,3]oxazin-2-yl}-3-. hydroxybutanoic acid; Atorvastatin epoxy pyrrolooxazin 6-hydroxy analog; Atorvastatin FXA Impurity; 3H-Oxireno[3,4]pyrrolo[2,1-b][1,3]oxazine-3-butanoic acid, 7-(4-fluorophenyl)hexahydro-β,7-dihydroxy-1b-(1-methylethyl)-7a-phenyl-1a-[(phenylamino)carbonyl]-; 7-(4-Fluorophenyl)hexahydro-β,7-dihydroxy-1b-(1-methylethyl)-7a-phenyl-1a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3]oxazine-3-butanoic acid. CAS No. 873950-17-5. Pack Sizes: 10 mg. Product ID: B1370-148308. Molecular formula: C33H35FN2O7. Mole weight: 590.65. Custom synthesis is available. Send your inquiries for more information.
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Atorvastatin Cyclic Sodium Salt (Isopropyl) Impurity
An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Group: Pharmaceutical. Alternative Names: 4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H -pyrrolo[2,1-b][1,3]oxazin-2-yl}-3-hydroxybutanoic acid sodium salt; Atorvastatin Cyclic Isopropyl Impurity; Atorvastatin Epoxy Pyrrolooxazin 6-Hydroxy Analog (USP); Atorvastatin Cyclic 6-Hydroxy Impurity. CAS No. 1316291-19-6. Pack Sizes: 2.5 mg. Product ID: B1370-008834. Molecular formula: C33H34FN2NaO7. Mole weight: 612.62. Custom synthesis is available. Send your inquiries for more information.
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Atorvastatin Ethyl Ester
Atorvastatin Ethyl Ester is the impurity of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Group: Pharmaceutical. Alternative Names: (3R,5R)-Ethyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, ethyl ester, (βR,δR)-; Ethyl (βR,δR)-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoate; Ethyl (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate. CAS No. 1146977-93-6. Pack Sizes: 25 mg. Product ID: B2694-466959. Molecular formula: C35H39FN2O5. Mole weight: 586.71. Custom synthesis is available. Send your inquiries for more information.
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Atorvastatin Lactam Sodium Salt Impurity
Atorvastatin Lactam Sodium Salt Impurity is a photodegradation product of Atorvastatin. It is a cyclic impurity of Atorvastatin. Group: Pharmaceutical. Alternative Names: 1H-Pyrrole-1-heptanoic acid, 5-(4-fluorophenyl)-2,3-dihydro-β,δ-dihydroxy-3-(1-methylethyl)-2-oxo-4-phenyl-3-[(phenylamino)carbonyl]-, sodium salt (1:1), (βR,δR,3R)-; 1H-Pyrrole-1-heptanoic acid, 5-(4-fluorophenyl)-2,3-dihydro-β,δ-dihydroxy-3-(1-methylethyl)-2-oxo-4-phenyl-3-[(phenylamino)carbonyl]-, monosodium salt, [3R-[1(βR*,δR*),3R*]]-; Atorvastatin Lactam Sodium Salt Impurity (3R-isomer); sodium (3R,5R)-7-((R)-5-(4-fluorophenyl)-3-isopropyl-2-oxo-4-phenyl-3-(phenylcarbamoyl)-2,3-dihydro-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate. CAS No. 148217-40-7. Pack Sizes: 5 mg. Product ID: B2694-466956. Molecular formula: C33H34FN2O6Na. Mole weight: 596.62. Custom synthesis is available. Send your inquiries for more information.
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Atorvastatin Methyl Ester
Atorvastatin Methyl Ester is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Group: Pharmaceutical. Alternative Names: (βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Methyl Ester; (3R,5R)-Methyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbaMoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, methyl ester, (βR,δR)-; Methyl (βR,δR)-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoate. CAS No. 345891-62-5. Pack Sizes: 50 mg. Product ID: B0190-466944. Molecular formula: C34H37FN2O5. Mole weight: 572.68. Custom synthesis is available. Send your inquiries for more information.
Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide is a prominent compound in the research of dyslipidemia and associated cardiovascular disorders. Its efficacious mechanism of action lies in its tremendous capacity to inhibit HMG-CoA reductase, a pivotal enzyme profoundly engaged in the intricate process of cholesterol biosynthesis. Uses: Atorvastatin (a791750) impurity. Group: Pharmaceutical. Alternative Names: (3R,5R)-7-[[(3R,5R)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-heptanoic Acid Calcium Salt. CAS No. 1105067-87-5. Pack Sizes: 10 mg. Product ID: B0190-258830. Molecular formula: C40H48FN3O8?0.5Ca. Mole weight: 736.86. Custom synthesis is available. Send your inquiries for more information.
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Atorvastatin USP Related Compound B calcium salt
Atorvastatin USP Related Compound B is an impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Group: Pharmaceutical. Alternative Names: USP Atorvastatin Related Compound B; Calcium (3S,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate (1:2); Atorvastatin 3S,5R Isomer; (3S,5R)-7-[3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid, calcium salt; (βS,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt (2:1), (βS,δR)-; Atorvastatin Related Compound B; (3S,5R)-Atorvastatin Calcium Salt. CAS No. 887196-25-0. Pack Sizes: 10 mg. Product ID: B2694-168853. Molecular formula: C66H68CaF2N4O10. Mole weight: 1155.34. Custom synthesis is available. Send your inquiries for more information.
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Atorvastatin USP Related Compound C
Atorvastatin USP Related Compound C is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Group: Pharmaceutical. Alternative Names: USP Atorvastatin Related Compound C; Calcium (3R,5R)-7-[2,3-Bis(4-fluorophenyl)-5-isopropyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate (1:2); Atorvastatin Difluoro impurity; (3R,5R)-7-[3-(phenylcarbamoyl)-4,5-bis(4-fluorophenyl)-2-isopropyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid, calcium salt; (βR,δR)-2,3-Bis(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt; 1H-Pyrrole-1-heptanoic acid, 2,3-bis(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-, calcium salt (2:1), (βR,δR)-; Atorvastatin Related Compound C; Difluoro Atorvastatin Calcium Salt. CAS No. 693793-53-2. Pack Sizes: 20 mg. Product ID: B2694-168854. Molecular formula: C66H66CaF4N4O10. Mole weight: 1191.32. Custom synthesis is available. Send your inquiries for more information.
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Atorvastatin USP Related Compound E
Atorvastatin USP Related Compound E is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Group: Pharmaceutical. Alternative Names: USP Atorvastatin Related Compound E; Calcium (3S,5S)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate (1:2); Atorvastatin 3S,5S Enantiomer; (3S,5S)-7-[3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid, calcium salt; Atorvastatin Related Compound E; (3S,5S)-Atorvastatin Calcium Salt; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt (2:1), (βS,δS)-. CAS No. 1105067-88-6. Pack Sizes: 5 mg. Product ID: B0190-466957. Molecular formula: C66H68CaF2N4O10. Mole weight: 1155.38. Custom synthesis is available. Send your inquiries for more information.
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Avagacestat
BMS-708163 is a potent and orally bioavailable inhibitor of γ-secretase that more potently inhibits the cleavage of APP (IC50 = 0.30 nM) to Aβ40 than signaling through Notch (IC50s = 58 nM). Uses: Gamma secretase inhibitors and modulators. Group: Pharmaceutical. Alternative Names: Avagacestat; BMS 708163; (2R)-2-[(4-chlorophenyl)sulfonyl-[[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide. CAS No. 1146699-66-2. Pack Sizes: 50 mg. Product ID: B0084-286394. Molecular formula: C20H17ClF4N4O4S. Mole weight: 520.89. Custom synthesis is available. Send your inquiries for more information.
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AZD9496
AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist. AZD9496 can induce ERα degradation in breast cancer cell lines at picomolar concentrations. Group: Pharmaceutical. Alternative Names: (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic acid; AZD9496; AZD-9496; AZD 9496. CAS No. 1639042-08-2. Pack Sizes: 25 mg. Product ID: B0084-470890. Molecular formula: C25H25F3N2O2. Mole weight: 442.48. Custom synthesis is available. Send your inquiries for more information.
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Broflanilide
Broflanilide, a GABA antagonist, is an insecticide that has high larvicidal activity against Spodoptera litura and is effective against pests with resistance to cyclodienes and fipronil. Group: Pharmaceutical. Alternative Names: N-[2-Bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl]-2-fluoro-3-(N-methylbenzamido)benzamide; 3-(Benzoylmethylamino)-N-[2-bromo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]-2-fluorobenzamide; 2-Fluoro-3-(N-methylbenzamido)-N-[2-bromo-4-(heptafluoroisopropyl)-6-(trifluoromethyl)phenyl]benzamide; 6'-Bromo-α,α,α,2-tetrafluoro-3-(N-methylbenzamido)-4'-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]benz-o-toluidide. CAS No. 1207727-04-5. Pack Sizes: 50 mg. Product ID: B1370-071090. Molecular formula: C25H14BrF11N2O2. Mole weight: 663.28. Custom synthesis is available. Send your inquiries for more information.
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Canagliflozin-[d4]
Canagliflozin D4 is a labelled Canagliflozin. Canagliflozin is a medication used for the treatment of type 2 diabetes. Group: Pharmaceutical. Alternative Names: (2S,3R,4R,5S,6R)-2-[3-({5-[4-fluoro(2,3,5,6-D4)phenyl]thiophen-2-yl}methyl)-4-methylphenyl]-6-(hydroxymethyl)oxane-3,4,5-triol. CAS No. 1997338-61-0. Pack Sizes: 5 mg. Product ID: BLP-011203. Molecular formula: C24H21D4FO5S. Mole weight: 448.54. Custom synthesis is available. Send your inquiries for more information.
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Cebranopadol
Cebranopadol is a novel first-in-class compound with potent agonist activity on opioid receptor like-1(ORL-1) and the well established mu opioid receptor. It showed antinociceptive and antihypertensive effects in a variety of different animal models of pain, suggesting its potential use for the treatment of chronic pain states. Group: Pharmaceutical. Alternative Names: GRT6005; GRT 6005; GRT-6005; 6-fluoro-N,N-dimethyl-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine. CAS No. 863513-91-1. Pack Sizes: 10 mg. Product ID: B0084-474871. Molecular formula: C24H27FN2O. Mole weight: 378.491. Custom synthesis is available. Send your inquiries for more information.
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CNX-2006
CNX-2006 is a potent and mutant-selective EGFR inhibitor with excellent in vitro activity in cells with activating EGFR mutations, as well as in cells harbouring the T790M mutation. CNX-2006 is the prototype for CO-1686, which is currently in a Phase I clinical trial for the treatment of EGFR-mutant lung cancer. Group: Pharmaceutical. Alternative Names: CNX2006; CNX 2006; N-[3-[[2-[4-[[1-(2-fluoroethyl)azetidin-3-yl]amino]-2-methoxyanilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide. CAS No. 1375465-09-0. Pack Sizes: 10 mg. Product ID: B0084-462328. Molecular formula: C26H27F4N7O2. Mole weight: 545.543. Custom synthesis is available. Send your inquiries for more information.
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CTLA-4 inhibitor
CTLA-4 inhibitor is an inhibitor of CTLA-4, an immune checkpoint negatively regulating T cell function. CTLA-4 is thought to regulate T-cell proliferation early in an immune response, primarily in lymph nodes. Group: Pharmaceutical. Alternative Names: MDK24720; MDK 24720; MDK-24720; CTLA-4 inhibitor. 2-(4-Fluorophenyl)-6-methyl-4-(3-(trifluoromethyl)phenyl)-1,2-dihydrodipyrazolo[3,4-b:3',4'-d]pyridin-3(6H)-one; EX-A913. CAS No. 635324-72-0. Pack Sizes: 10 mg. Product ID: B0084-284810. Molecular formula: C21H13F4N5O. Mole weight: 427.363. Custom synthesis is available. Send your inquiries for more information.
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D18024
D-18024 is a Phthalazinonderivat antiallergic and antihistaminic activity. Group: Pharmaceutical. Alternative Names: 4-[(4-fluorophenyl)methyl]-2-[1-(2-phenylethyl)azepan-4-yl]phthalazin-1-one;hydrochloride; D-18024; D18024; D 18024. CAS No. 110406-33-2. Pack Sizes: 1mg;1g;10g. Product ID: 110406-33-2. Molecular formula: C29H31ClFN3O. Mole weight: 492.03. Custom synthesis is available. Send your inquiries for more information.
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Deruxtecan
Deruxtecan analog is a drug-linker conjugate for antibody-drug conjugate (ADC). Deruxtecan, a topoisomerase I inhibitor, is an exatecan derivative (DX-8951 derivative) with a cleavable pepetide linker and a maleimide group. The maleimide group in Deruxtecan can react with antibody to form antibody-drug conguates (ADC) such as Trastuzumab deruxtecan (DS-8201a), which is a HER2-targeting antibody-drug conjugate. DS-8201a significantly suppressed tumor growth in an immunocompetent mouse model with human HER2-expressing CT26.WT (CT26.WThHER2) cells. DS-8201a is currently in clinical trials. Group: Pharmaceutical. Alternative Names: Deruxtecan Analog; Deruxtecan, Trastuzumab deruxtecan; DS-8201a; DS8201a; DS 8201a; Exatecan derivative; DX-8951 derivative; DX 8951; DX8951; N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycylglycyl-L-phenylalanyl-N-[(2-{[(1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl]amino}-2-oxoethoxy)methyl]glycinamide. CAS No. 1599440-13-7. Pack Sizes: 5 mg. Product ID: BBF-05879. Molecular formula: C52H56FN9O13. Mole weight: 1034.05. Custom synthesis is available. Send your inquiries for more information.
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Desacetyl-N,O-descarbonyl Linezolid
Desacetyl-N,O-descarbonyl Linezolid is an impurity of Linezolid, an oxazolidinone antimicrobial that inhibits bacterial mRNA translation. Group: Pharmaceutical. Alternative Names: (2S)-1-Amino-3-[[3-fluoro-4-(4-morpholinyl)phenyl]amino]-2-propanol. CAS No. 333753-72-3. Pack Sizes: 250 mg. Product ID: B0073-472428. Molecular formula: C13H20FN3O2. Mole weight: 269.32. Custom synthesis is available. Send your inquiries for more information.
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Desfluoro Ezetimibe
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. Alternative Names: Ezetimibe Desfluoroaniline analog; (3R,4S)-3-[(S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one; (3R,4S)-3-[(3S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenyl-2-azetidinone; 1-Desfluoro Ezetimibe; Ezetimibe Desfluoro Analog. CAS No. 302781-98-2. Pack Sizes: 10 mg. Product ID: B0026-462100. Molecular formula: C24H22FNO3. Mole weight: 391.45. Custom synthesis is available. Send your inquiries for more information.
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Elagolix sodium
Elagolix is a selective gonadotropin-releasing hormone receptor (GnRHR) antagonist with KD of 54 pM. It is in phase III clinical trials for the treatment of endometriosis and uterine leiomyoma. Elagolix was also under investigation for the treatment of prostate cancer and benign prostatic hyperplasia, but development for these indications was ultimately not pursued. Uses: Endometriosis; uterine leiomyoma. Group: Pharmaceutical. Alternative Names: Sodium (R)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate; NBI56418; NBI-56418; NBI 56418. CAS No. 832720-36-2. Pack Sizes: 25 mg. Product ID: B0084-354739. Molecular formula: C32H29F5N3NaO5. Mole weight: 653.58. Custom synthesis is available. Send your inquiries for more information.
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Encorafenib
Encorafenib, also known as LGX-818, is an orally available Raf kinase inhibitor with potential antineoplastic activity. LGX818 specifically inhibits Raf kinase, a serine/threonine enzyme in the RAF/mitogen-activated protein kinase kinase (MEK)/extracellular signal-related kinase (ERK) signaling pathway. By inhibiting the activation of the RAF/MEK/ERK signaling pathway, the administration of LGX818 may result in a decrease in proliferation of tumor cells. The Raf mutation BRAF V600E is frequently upregulated in a variety of human tumors and results in the constitutive activation of the RAF/MEK/ERK signaling pathway that regulates cellular proliferation and survival. Group: Pharmaceutical. Alternative Names: LGX818; LGX-818; LGX 818; Methyl N-[(2S)-1-[[4-[3-[5-chloro-2-fluoro-3-(methanesulfonamido)phenyl]-1-propan-2-ylpyrazol-4-yl]pyrimidin-2-yl]amino]propan-2-yl]carbamate. CAS No. 1269440-17-6. Pack Sizes: 150 mg. Product ID: B0084-462563. Molecular formula: C22H27ClFN7O4S. Mole weight: 540.011. Custom synthesis is available. Send your inquiries for more information.
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Enzalutamide
Enzalutamide is an androgen-receptor (AR) antagonist with IC50 of 36 nM. It inhibits the activity of prostate cancer cell Ars, which over expressed in prostate cancer. Uses: Potential antineoplastic agent. Group: Pharmaceutical. Alternative Names: MDV3100; MDV 3100; MDV-3100; 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide; Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methyl-; 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide; S-Enzalutamide; Xtandi. CAS No. 915087-33-1. Pack Sizes: 500 mg. Product ID: B0084-155497. Molecular formula: C21H16F4N4O2S. Mole weight: 464.44. Custom synthesis is available. Send your inquiries for more information.
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Enzalutamide-[d6]
Enzalutamide-[d6] is a deuterium labelled form of Enzalutamide. Enzalutamide is a nonsteroidal antiandrogen medication which is used in the treatment of prostate cancer. Group: Pharmaceutical. Alternative Names: 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide-d6; Enzalutamide D6. CAS No. 1443331-94-9. Pack Sizes: 5 mg. Product ID: BLP-005318. Molecular formula: C21H10D6F4N4O2S. Mole weight: 470.47. Custom synthesis is available. Send your inquiries for more information.
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Ezetimibe Deprotected Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L13) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. Alternative Names: (S)-3-((2R,5S)-5-(4-fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one. CAS No. 1185883-40-2. Pack Sizes: 20 mg. Product ID: B1370-175318. Molecular formula: C33H30F2N2O5. Mole weight: 572.61. Custom synthesis is available. Send your inquiries for more information.
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Ezetimibe Impurity 9
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L43) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. Alternative Names: (S)-3-((2R,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one; 3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl(amino)]][4-[trimethylsilyl]-oxy]phenyl]methyl]-1-oxo-5-[(trimethylsily)-oxy]pentyl]-4-phenyl-(4S)-2-oxazolidinone. CAS No. 272778-12-8. Pack Sizes: 25 g. Product ID: B2694-089119. Molecular formula: C39H46F2N2O5Si2. Mole weight: 716.98. Custom synthesis is available. Send your inquiries for more information.
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FDI 6
FDI 6 is an inhibitor of the Forkhead box protein M1 transcription factor (FOXM1) (IC50 value 22.5 μM) that suppresses FOXM1 binding to DNA. FDI6 displaces ?FOXM1 from genomic targets in MCF-7 breast cancer cells, and downregulates concomitant transcription. Group: Pharmaceutical. Alternative Names: FDI-6; FDI 6; FDI6; NCGC00099374; NCGC-00099374; NCGC 00099374; 3-amino-6-thiophen-2-yl-4-trifluoromethyl-thieno[2,3-b]pyridine-2-carboxylic acid (4-fluoro-phenyl)-amide; 3-amino-N-(4-fluorophenyl)-6-(2-thienyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; 3-amino-N-(4-fluorophenyl)-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; AC1NPA9B. CAS No. 313380-27-7. Pack Sizes: 50 mg. Product ID: B0084-054874. Molecular formula: C19H11F4N3OS2. Mole weight: 437.43. Custom synthesis is available. Send your inquiries for more information.
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Flurbiprofen
Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) belonging to the propionic acid class. It exerts analgesic, anti-inflammatory, and antipyretic effects by reversibly inhibiting cyclooxygenase (COX) enzymes, thereby reducing prostaglandin synthesis. Clinically, it is used to manage pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and postoperative discomfort. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. Alternative Names: 2-Fluoro-α-methyl[1,1'-biphenyl]-4-acetic acid; (±)-Flurbiprofen; 2-(2-Fluoro-1,1'-biphenyl-4-yl)propanoic acid; 2-(2-Fluoro-4-biphenyl)propionic acid; 2-(2-Fluoro-4-biphenylyl)propanoic acid; 2-(2-Fluoro-4-biphenylyl)propionic acid; 2-Fluoro-α-methyl-4-biphenylacetic acid; 2-Fluoro-α-methyl-4-diphenylacetic acid; 3-Fluoro-4-phenylhydratropic acid; Adfeed; Ansaid; Antadys; BTS 18322; Cebutid; dl-2-(2-Fluoro-4-biphenylyl)propionic acid; dl-Flurbiprofen; Flugalin; Flurbifen; Fluribiprofen; Fluroben; Flurofen; FP 70; FP-A; Froben; rac-Flurbiprofen; Racemic flurbiprofen; Stayban; Synalgo; U 27182; Urbifen; Zepolas. CAS No. 5104-49-4. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04023. Molecular formula: C15H13FO2. Mole weight: 244.26. Custom synthesis is available. Send your inquiries for more information.
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Flurbiprofen Sodium
Flurbiprofen Sodium is a nonsteroidal anti-inflammatory drug (NSAID) derived from propionic acid. It functions as a potent inhibitor of cyclooxygenase (COX) enzymes, thereby reducing the production of prostaglandins, which are mediators of pain, inflammation, and fever. Group: Pharmaceutical. Alternative Names: [1,1'-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, sodium salt (1:1); 2-(2-Fluorobiphenyl-4-yl)propionic acid sodium salt; 2-Fluoro-α-methyl-4-diphenylacetic acid sodium salt; Flurbiprofen sodium salt; Ocufen; Ocuflur; Sodium 3-fluoro-4-phenylhydratropate; Sodium flurbiprofen. CAS No. 56767-76-1. Pack Sizes: 5 g. Product ID: BBF-03906. Molecular formula: C15H12FNaO2. Mole weight: 266.24. Custom synthesis is available. Send your inquiries for more information.
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Fosaprepitant-[d4] Dimeglumine
Fosaprepitant-[d4] Dimeglumine is a labelled form of Fosaprepitant Dimeglumine, which has been found to be a selective neurokinin-1 (NK-1) receptor antagonist. Group: Pharmaceutical. Alternative Names: [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl-d4)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol; Fosaprepitant D4 Dimeglumine; MK-0517-d4; L785298-d4. Pack Sizes: 25 mg. Product ID: BLP-005503. Molecular formula: C37H52D4F7N6O16P. Mole weight: 1008.86. Custom synthesis is available. Send your inquiries for more information.
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GNF 5837
GNF 5837 is a potent and selective pan-Trk inhibitor that blocks tumor gowth in a mouse xenograft model derived from RIE cells expressing both TRKA and NGF. GNF 5837 displays antiproliferative effects in cellular Ba/F3 assays with IC50 values of 7, 9 and 11 nM for cells expressing Tel-TrkC, Tel-TrkB and Tel-TrkA respectively. Group: Pharmaceutical. Alternative Names: GNF5837; GNF-5837; GNF 5837. 1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-methyl-3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]urea. CAS No. 1033769-28-6. Pack Sizes: 50 mg. Product ID: B0084-462361. Molecular formula: C28H21F4N5O2. Mole weight: 535.503. Custom synthesis is available. Send your inquiries for more information.
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Imlunestrant
Imlunestrant, an orally active selective estrogen receptor degrader (SERD) with potential antineoplastic activity, can be used in the ER+, HER2-advanced breast cancer research. Group: Pharmaceutical. Alternative Names: LY-3484356; (R)-5-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)phenyl)-8-(trifluoromethyl)-5H-chromeno[4,3-c]quinolin-2-ol; 5H-(1)Benzopyrano(4,3-c)quinolin-2-ol, 5-(4-(2-(3-(fluoromethyl)-1-azetidinyl)ethoxy)phenyl)-8-(trifluoromethyl)-, (5R)-. CAS No. 2408840-26-4. Pack Sizes: 5 mg. Product ID: B1370-059787. Molecular formula: C29H24F4N2O3. Mole weight: 524.51. Custom synthesis is available. Send your inquiries for more information.
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Lapatinib-[13C,d7]
Lapatinib-[13C,d7] is the labelled analogue of Lapatinib, a reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. It can be used for the treatment of breast cancer and other solid tumours. Group: Pharmaceutical. Alternative Names: Lapatinib-13C,D7; Lapatinib Ditosylate-13C,d7; Tykerb-13C,d7; GW 572016-13C,d7; Tyverb-13C,d7; N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-[5-({[2-(13C,D3)methanesulfonyl(D4)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine. CAS No. 1210608-87-9. Pack Sizes: 1 mg. Product ID: BLP-011601. Molecular formula: C28[13C]H19D7ClFN4O4S. Mole weight: 589.09. Custom synthesis is available. Send your inquiries for more information.
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