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| Product | Description | |
|---|---|---|
| Fludarabine Impurities | Fludarabine Impurities, subtle yet significant chemical entities, arise during the synthesis and refinement of Fludarabine, a vital chemotherapeutic used against chronic lymphocytic leukemia and low-grade non-Hodgkin's lymphoma. In-depth comprehension and meticulous regulation of these impurities are paramount in the biomedical field, ensuring optimal drug performance and safeguarding patient health. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Fludarabine phosphate | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C10H13FN5O7P. CAS No. 75607-67-9. Prepack ID : 56054450-1g. Molecular Weight : 365.21. |  |
| PRT062607 monohydrochloride | PRT062607, also known as PRT2607, P505-15, and BIIB057, is a novel, highly selective, and orally bioavailable small molecule SYK inhibitor (SYK IC(50) = 1 nM) with anti-SYK activity that is at least 80-fold greater than its affinity for other kinases. PRT062607 successfully inhibited SYK-mediated B-cell receptor signaling and decreased cell viability in NHL and CLL. Oral dosing in mice prevented BCR-mediated splenomegaly and significantly inhibited NHL tumor growth in a xenograft model. In addition, combination treatment of primary CLL cells with PRT062607 plus fludarabine produced synergistic enhancement of activity at nanomolar concentrations. PRT062607 may be a therapeutic agent for B-cell malignancies. A dose finding study in healthy volunteers has been completed. Group: Pharmaceutical. CAS No. 1370261-97-4. Pack Sizes: 10 mg. Product ID: B2693-457962. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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