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| Product | Description | |
|---|---|---|
| Fludarabine phosphate | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C10H13FN5O7P. CAS No. 75607-67-9. Prepack ID : 56054450-1g. Molecular Weight : 365.21. |  |
| PRT062607 monohydrochloride | PRT062607, also known as PRT2607, P505-15, and BIIB057, is a novel, highly selective, and orally bioavailable small molecule SYK inhibitor (SYK IC(50) = 1 nM) with anti-SYK activity that is at least 80-fold greater than its affinity for other kinases. PRT062607 successfully inhibited SYK-mediated B-cell receptor signaling and decreased cell viability in NHL and CLL. Oral dosing in mice prevented BCR-mediated splenomegaly and significantly inhibited NHL tumor growth in a xenograft model. In addition, combination treatment of primary CLL cells with PRT062607 plus fludarabine produced synergistic enhancement of activity at nanomolar concentrations. PRT062607 may be a therapeutic agent for B-cell malignancies. A dose finding study in healthy volunteers has been completed. Group: Pharmaceutical. Alternative Names: 5-Pyrimidinecarboxamide, 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-, hydrochloride (1:1); PRT2607 HCl; PRT-2607 HCl; PRT 2607 HCl; RPRT062607 HCl; PRT-062607 HCl; PRT 062607 HCl; P505-15 HCl; BIIB057 HCl; BIIB 057 HCl; 2-[[(1R,2S)-2-Aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-5-pyrimidinecarboxamide hydrochloride. CAS No. 1370261-97-4. Pack Sizes: 10 mg. Product ID: B2693-457962. Molecular formula: C19H23N9O.HCl. Mole weight: 429.91. Custom synthesis is available. Send your inquiries for more information. |  London |
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