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| Product | Description | |
|---|---|---|
| Fibroblast Growth Factor-Basic | Fibroblast Growth Factor-Basic is a growth factor encoded by the FGF2 gene. It is found in basement membranes and sub-endothelial extracellular matrix. FGF2 specifically binds to fibroblast growth factor receptor (FGFR) proteins. Group: Pharmaceutical. Alternative Names: hBFGF; FGF-Basic; Basic fibroblast growth factor; bFGF. CAS No. 106096-93-9. Pack Sizes: 1 mg. Product ID: B0084-358404. Custom synthesis is available. Send your inquiries for more information. |  London |
| ABT-510 | ABT-510 is a synthetic peptide that mimics the anti-angiogenic activity of the endogenous protein thrombospondin-1 (TSP-1). ABT-510 inhibits the actions of several pro-angiogenic growth factors important to tumor neovascularization; these pro-angiogenic growth factors include vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF)), hepatocyte growth factor (HGF), and interleukin 8 (IL-8). Group: Pharmaceutical. Alternative Names: ABT-510; ABT 510; ABT510. CAS No. 251579-55-2. Pack Sizes: 100 mg. Product ID: B2693-462640. Molecular formula: C46H83N13O11. Mole weight: 994.25. Custom synthesis is available. Send your inquiries for more information. | London |
| α-Tocotrienol | α-Tocotrienol is a form of vitamin E, a class of eight fat-soluble compounds. It was shown to induce apoptosis and inhibit proliferation, and down-regulate the fibroblast growth factor receptor-1 (FGFR1). Uses: Antioxidants. Group: Pharmaceutical. Alternative Names: (2R)-2,5,7,8-tetramethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl]-3,4-dihydrochromen-6-ol. CAS No. 58864-81-6. Pack Sizes: 25 mg. Product ID: B0005-190073. Molecular formula: C29H44O2. Mole weight: 424.7. Custom synthesis is available. Send your inquiries for more information. | London |
| ARQ-087 | ARQ-087, also known as Derazantinib, is an oral fibroblast growth factor receptor (FGFR) inhibitor with antitumor property. FGFR plays a role in the regulation of key cellular behaviors including proliferation, cell differentiation and so on. FGFR dysregulation is considered as a driver in multiple cancers. ARQ 087 binds to FGFR and effectively inhibits the activation of FGFR thus can suppress tumorigenesis and tumor growth. Group: Pharmaceutical. Alternative Names: ARQ 087; ARQ087; ARQ-087; Derazantinib; (6R)-6-(2-fluorophenyl)-N-[3-[2-(2-methoxyethylamino)ethyl]phenyl]-5,6-dihydrobenzo[h]quinazolin-2-amine. CAS No. 1234356-69-4. Pack Sizes: 5 mg. Product ID: B0084-008116. Molecular formula: C29H29FN4O. Mole weight: 468.576. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-4547 | AZD4547 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. AZD4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and, so, the inhibition of tumor cell proliferation and tumor cell death. Group: Pharmaceutical. Alternative Names: AZD-4547; AZD 4547; AZD4547; N-{3-[2-(3,5-Dimethoxyphenyl)ethyl]-1h-Pyrazol-5-Yl}-4-[(3r,5s)-3,5-Dimethylpiperazin-1-Yl]benzamide. CAS No. 1035270-39-3. Pack Sizes: 100 mg. Product ID: B0084-456576. Molecular formula: C26H33N5O3. Mole weight: 463.582. Custom synthesis is available. Send your inquiries for more information. | London |
| BGJ-398 | BGJ398, also known as NVP-BGJ398, is a pan FGFR kinase inhibitor, and is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. BGJ398 selectively binds to and inhibits the activities of FGFRs, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Group: Pharmaceutical. Alternative Names: 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea; NVPBGJ398; NVPBGJ 398; NVPBGJ-398; BGJ398; BGJ-398; BG J398; Infigratinib. CAS No. 872511-34-7. Pack Sizes: 100 mg. Product ID: B2693-453477. Molecular formula: C26H31Cl2N7O3. Mole weight: 560.48. Custom synthesis is available. Send your inquiries for more information. | London |
| BLU-554 | BLU-554 is a potent and selective inhibitor of fibroblast growth factor receptor 4 (FGFR4) (IC50 = 5 nM), which is promisingly to be used for the treatment of hepatocellular carcinoma and cholangiocarcinoma. Group: Pharmaceutical. Alternative Names: BLU-554; BLU 554; BLU554, Fisogatinib; SCHEMBL16668287; EX-A841; MFCD30496704; N-[(3S,4S)-3-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino]oxan-4-yl]prop-2-enamide; BLU554. CAS No. 1707289-21-1. Pack Sizes: 10 mg. Product ID: B0084-008122. Molecular formula: C24H24Cl2N4O4. Mole weight: 503.38. Custom synthesis is available. Send your inquiries for more information. | London |
| D-γ-Tocotrienol | γ-Tocotrienol is a form of vitamin E, a class of eight fat-soluble compounds. It was shown to induce apoptosis and inhibit proliferation, and down-regulate the fibroblast growth factor receptor-1 (FGFR1). Group: Pharmaceutical. Alternative Names: [R-(E,E)]-3,4-Dihydro-2,7,8-trimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol; (2R)-3,4-dihydro-2,7,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-2H-1-benzopyran-6-ol; 2,7,8-trimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-6-chromanol; (2R)-3,4-Dihydro-2,7,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrien-1-yl]-2H-1-benzopyran-6-ol; (R)-γ-Tocotrienol; 7,8-Dimethyltocotrienol; Plastochromanol 3; γ-Tocotrienol. CAS No. 14101-61-2. Pack Sizes: 50 mg. Product ID: B0005-078430. Molecular formula: C28H42O2. Mole weight: 410.63. Custom synthesis is available. Send your inquiries for more information. | London |
| Dimethyl 3,3'-(((((2,2'-(piperazine-1,4-diyl)bis(acetyl))bis(methylazanediyl))bis(4,1-phenylene))bis(azanediyl))bis(phenylmethanylylidene))(3Z,3'E)-bis(2-oxoindoline-6-carboxylate) | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Group: Pharmaceutical. Alternative Names: Nintedanib Impurity 50. CAS No. 2410284-90-9. Pack Sizes: 1 mg. Product ID: B2694-478193. Molecular formula: C56H52N8O8. Mole weight: 965.08. Custom synthesis is available. Send your inquiries for more information. | London |
| Erdafitinib | Erdafitinib, also known as JNJ-42756493, is a potent and selective orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. Group: Pharmaceutical. Alternative Names: JNJ-42756493; JNJ 42756493; JNJ42756493; Erdafitinib. CAS No. 1346242-81-6. Pack Sizes: 250 mg. Product ID: B0084-470835. Molecular formula: C25H30N6O2. Mole weight: 446.55. Custom synthesis is available. Send your inquiries for more information. | London |
| FGF-401 | FGF-401 is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4) (IC50 = 1.9 nM) developed for the treatment of solid tumor. Group: Pharmaceutical. Alternative Names: FGF401; FGF-401; FGF 401; roblitinib; N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide. CAS No. 1708971-55-4. Pack Sizes: 10 mg. Product ID: B0084-007362. Molecular formula: C25H30N8O4. Mole weight: 506.56. Custom synthesis is available. Send your inquiries for more information. | London |
| Futibatinib | Futibatinib is an orally bioavailable, selective and irreversible inhibitor of fibroblast growth factor receptors (FGFRs), displaying antineoplastic activity. It inhibits FGFR-mediated signal transduction and tumor cell proliferation. Group: Pharmaceutical. Alternative Names: 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1-pyrazolo[3,4-d]pyrimidinyl]-1-pyrrolidinyl]-2-propen-1-one; 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one. CAS No. 1448169-71-8. Pack Sizes: 250 mg. Product ID: B2693-292398. Molecular formula: C22H22N6O3. Mole weight: 418.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Kerantinocyte Growth Factor | Recombinant Human KGF is an 18.9 kDa protein containing 163 amino residues. Group: Pharmaceutical. Alternative Names: Recombinant Human KGF; rhKGF; Fibroblastgrowth factor 7; KGF; hFGF-7;HBGF-7. CAS No. 148348-15-6. Pack Sizes: 50 mg. Product ID: B1370-167006. Mole weight: 18.9 kDa. Custom synthesis is available. Send your inquiries for more information. | London |
| Methyl 1-Acetyl-2-oxoindoline-6-carboxylate | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Group: Pharmaceutical. Alternative Names: 1-acetyl-2-oxo-3H-indole-6-carboxylic acid methyl ester; methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate. CAS No. 676326-36-6. Pack Sizes: 100 mg. Product ID: B1421-184191. Molecular formula: C12H11NO4. Mole weight: 233.22. Custom synthesis is available. Send your inquiries for more information. | London |
| Nintedanib Impurity D | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Group: Pharmaceutical. Alternative Names: (3Z)?-2,?3-Dihydro-3-[[[4-(methylamino)?phenyl]?amino]?phenylmethylene]?-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester. CAS No. 1987887-92-2. Pack Sizes: 100 mg. Product ID: B1421-478184. Molecular formula: C24H21N3O3. Mole weight: 399.45. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Methyl-2-(4-methyl-1-piperazinyl)-N-(4-nitrophenyl)acetamide | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Group: Pharmaceutical. Alternative Names: N-methyl-2-(4-methyl-1-piperazinyl)-N-(4-nitrophenyl)acetamide; N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide. CAS No. 1139453-98-7. Pack Sizes: 100 mg. Product ID: B1421-258623. Molecular formula: C14H20N4O3. Mole weight: 292.33. Custom synthesis is available. Send your inquiries for more information. | London |
| N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Group: Pharmaceutical. Alternative Names: N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide; 1038972-16-5; CS-0011633; N-Methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide (Nintedanib Impurity). CAS No. 1038972-16-5. Pack Sizes: 100 mg. Product ID: B1421-284921. Molecular formula: C13H18N4O3. Mole weight: 278.31. Custom synthesis is available. Send your inquiries for more information. | London |
| N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide hydrochloride | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Group: Pharmaceutical. CAS No. 2037385-84-3. Pack Sizes: 100 mg. Product ID: B1421-284922. Molecular formula: C13H19ClN4O3. Mole weight: 314.77. Custom synthesis is available. Send your inquiries for more information. | London |
| NVP-BGJ398 phosphate | Potent and selective inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinases 1, 2, 3 and 4 (with IC50 values of 0.9, 1.4, 1.0 and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4 respectively); it showed siginificant antitumor activity in RT112 bladder cancer xenografts models overexpressing wild-type FGFR3. Group: Pharmaceutical. Alternative Names: Infigratinib phosphate; BGJ-398 phosphate; NVP-BGJ398 phosphate; NVPBGJ398 phosphate. CAS No. 1310746-10-1. Pack Sizes: 50 mg. Product ID: B2693-463171. Molecular formula: C26H34Cl2N7O7P. Mole weight: 658.47. Custom synthesis is available. Send your inquiries for more information. | London |
| Pemigatinib | Pemigatinib is an inhibitor of fibroblast growth factor receptor types 1, 2, and 3 (FGFR1/2/3). Under the brand name Pemazyre, it is used as a medication for the treatment of adults with previously treated, unresectable locally advanced or metastatic cholangiocarcinoma. Group: Pharmaceutical. Alternative Names: INCB054828. CAS No. 1513857-77-6. Pack Sizes: 100 mg. Product ID: B2693-006403. Molecular formula: C24H27F2N5O4. Mole weight: 487.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Rogaratinib | Rogaratinib is a pan inhibitor of human fibroblast growth factor receptors (FGFRs). It reduced proliferation in FGFR-addicted cancer cell lines of various cancer types including lung, breast, colon and bladder cancer. Group: Pharmaceutical. Alternative Names: BAY-1163877; BAY 1163877; BAY1163877. CAS No. 1443530-05-9. Pack Sizes: 25 mg. Product ID: B2693-004563. Molecular formula: C23H26N6O3S. Mole weight: 466.6. Custom synthesis is available. Send your inquiries for more information. | London |
| SU5402 | SU5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor. Group: Pharmaceutical. Alternative Names: SU-5402; SU 5402. CAS No. 215543-92-3. Pack Sizes: 100 mg. Product ID: B2693-087527. Molecular formula: C17H16N2O3. Mole weight: 296.32054. Custom synthesis is available. Send your inquiries for more information. | London |
| SUN11602 | SUN11602 is a novel aniline compound, which mimics the neuroprotective mechanisms of basic fibroblast growth factor. In primary cultures of rat cerebrocortical neurons, SUN11602 and bFGF prevented glutamate-induced neuronal death. Group: Pharmaceutical. Alternative Names: SUN11602; SUN-11602; SUN 11602. 4-[[4-[[2-(4-amino-2,3,5,6-tetramethylanilino)acetyl]-methylamino]piperidin-1-yl]methyl]benzamide. CAS No. 704869-38-5. Pack Sizes: 100 mg. Product ID: B0084-462595. Molecular formula: C26H37N5O2. Mole weight: 451.615. Custom synthesis is available. Send your inquiries for more information. | London |
| Vosoritide | Vosoritide is a medicine used to treat achondroplasia. Vosoritide works by binding to a receptor (target) called natriuretic peptide receptor type B (NPR-B), which reduces the activity of fibroblast growth factor receptor 3 (FGFR3). Uses: Vosoritide, a synthetic analog of the human growth hormone receptor antagonist bmp-7, has emerged as a promising candidate in drug development, particularly in the area of ??rare genetic diseases characterized by impaired skeletal growth and development. achondroplasia is the most common form of disproportionate dwarfism and is characterized by abnormal skeletal growth and development, especially. Group: Pharmaceutical. Alternative Names: Voxzogo; BMN-111. CAS No. 1480724-61-5. Pack Sizes: 50 mg. Product ID: BAT-009108. Molecular formula: C176H290N56O51S3. Mole weight: 4103. Custom synthesis is available. Send your inquiries for more information. | London |
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