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| Product | Description | |
|---|---|---|
| Fasudil hydrochloride | Fasudil HCl, a 5-isoquinolinesulfonamide derivative, is a highly selective Rho-associated protein kinase inhibitor that might have a rate in romoting the recovery of neurological function, reducing clinical symptoms and the morbidity. Uses: Fasudil hcl, a 5-isoquinolinesulfonamide derivative, is a highly selective rho-associated protein kinase inhibitor that might have a rate in romoting the recovery of neurological function, reducing clinical symptoms and the morbidity. Group: Pharmaceutical. CAS No. 105628-07-7. Pack Sizes: 1 g. Product ID: B2693-053715. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Fasudil Impurities | Fasudil Impurities, integral in pharmaceutical research, aid in analyzing and optimizing Fasudil synthesis. This evaluation is pivotal, as Fasudil is a renowned Rho-kinase inhibitor employed in treating cerebral vasospasm and pulmonary hypertension. Their study ensures drug purity and effectiveness, enhancing therapeutic strategies against these cardiovascular disorders. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Hydroxyfasudil Hydrochloride | Hydroxyfasudil Hydrochloride, an active metabolite of Fasudil, preferentially inhibits Rho-kinase and plays a central role in the pathogenesis of coronary artery spasm. It is reported to inhibit neutrophil migration and exhibit potent vasodilatory effects in vivo. Group: Pharmaceutical. CAS No. 155558-32-0. Pack Sizes: 200 mg. Product ID: B0084-261912. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| RKI-1447 | RKI-1447 is a potent Rho-associated kinase (ROCK) inhibitor with IC50 values of 14.5 and 6.2 nM for ROCK1 and ROCK2 respectively. It exhibits significant anti-invasive and antitumor activity in breast cancer. In combination with fasudil, it was shown to induce differentiation of mESCs and hESCs to endoderm via ROCK inhibition. Group: Pharmaceutical. CAS No. 1342278-01-6. Pack Sizes: 25 mg. Product ID: B0084-462699. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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