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| Product | Description | |
|---|---|---|
| Exherin | Exherin, also known as ADH-1, is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitively binds to and blocks N-cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis. N-cadherin, a cell- surface transmembrane glycoprotein of the cadherin superfamily of proteins involved in calcium-mediated cell-cell adhesion and signaling mechanisms; may be upregulated in some aggressive tumors and the endothelial cells and pericytes of some tumor blood vessels. Group: Pharmaceutical. Alternative Names: NSC729477; ADH-1; NSC7 29477; ADH 1; NSC-729477; ADH1. CAS No. 229971-81-7. Pack Sizes: 10 mg. Product ID: BAT-010745. Molecular formula: C22H34N8O6S2. Mole weight: 570.69. Custom synthesis is available. Send your inquiries for more information. |  London |
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