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| Product | Description | |
|---|---|---|
| Evofosfamide | Evofosfamide is a hypoxia-activated prodrug consisting of a 2-nitroimidazole phosphoramidate conjugate with potential antineoplastic activity. The 2-nitroimidazole moiety of hypoxia-activated prodrug TH-302 acts as a hypoxic trigger, releasing the DNA-alkylating dibromo isophosphoramide mustard moiety within hypoxic regions of tumors. Normoxic tissues may be spared due to the hypoxia-specific activity of this agent, potentially reducing systemic toxicity. Group: Pharmaceutical. Alternative Names: TH-302; TH 302; TH302; 2-bromo-N-[(2-bromoethylamino)-[(3-methyl-2-nitroimidazol-4-yl)methoxy]phosphoryl]ethanamine. CAS No. 918633-87-1. Pack Sizes: 50 mg. Product ID: B0084-460516. Molecular formula: C9H16Br2N5O4P. Mole weight: 449.04. Custom synthesis is available. Send your inquiries for more information. |  London |
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