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| Product | Description | |
|---|---|---|
| 17β-Dihydro Equilin | The 17β-metabolite of Equilin. Equilin is one of the estrogens present in the mixture of estrogens isolated from horse urine and marketed as Premarin. Group: Pharmaceutical. Alternative Names: (17β)-Estra-1,3,5(10),7-tetraene-3,17-diol; Estra-1,3,5(10),7-tetraene-3,17β-diol; 7-Dehydroestradiol. CAS No. 3563-27-7. Pack Sizes: 10 mg. Product ID: B0851-305731. Molecular formula: C18H22O2. Mole weight: 270.37. Custom synthesis is available. Send your inquiries for more information. |  London |
| 3-O-Methyl-Estrone | A derivative of Estrone. Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol. Group: Pharmaceutical. Alternative Names: 3-Methoxy-1,3,5(10)-estratrien-17-one. CAS No. 1624-62-0. Pack Sizes: 1mg;1g;10g. Product ID: NP3084. Molecular formula: C19H24O2. Mole weight: 284.4. Custom synthesis is available. Send your inquiries for more information. | London |
| 6-Ketoestradiol | A derivative of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Group: Pharmaceutical. Alternative Names: 6-Oxoestradiol; 6-Keto 17β-Estradiol; (17β)-3,17-Dihydroxyestra-1,3,5(10)-trien-6-one; 3,17β-Dihydroxyestra-1,3,5(10)-trien-6-one; 1,3,5(10)-Estratrien-3,17β-diol-6-one; Estradiol Related Compound C. CAS No. 571-92-6. Pack Sizes: 10 g. Product ID: B1370-375346. Molecular formula: C18H22O3. Mole weight: 286.37. Custom synthesis is available. Send your inquiries for more information. | London |
| 6-Keto Fulvestrant | 6-Keto Fulvestrant is an impurity of Fulvestrant, an estrogen receptor antagonist used as a medication indicated for the treatment of hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Group: Pharmaceutical. Alternative Names: 6-Keto-Fulvestrant; (7a,17ss)-7-[9-[4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]-3,17ss-dihydroxyestra-1,3,5(10)-trien-6-one. Pack Sizes: 10 mg. Product ID: B2694-471908. Molecular formula: C32H45F5O4S. Mole weight: 620.77. Custom synthesis is available. Send your inquiries for more information. | London |
| 8-Prenylnaringenin | 8-Prenylnaringenin is a flavonoid derivative isolated from the herbs of Humulus lupulus. Uses: Estrogenic activity. Group: Pharmaceutical. Alternative Names: (2S)- 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one. CAS No. 53846-50-7. Pack Sizes: 50 mg. Product ID: NP2088. Molecular formula: C20H20O5. Mole weight: 340.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Abiraterone Related Compound 4 (Prasterone Acetate Triflate) | An impurity of Abiraterone, a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. Group: Pharmaceutical. Alternative Names: Abiraterone Impurity 4, Prasterone Acetate Triflate. CAS No. 115375-60-5. Pack Sizes: 1mg;1g;10g. Product ID: 115375-60-5. Molecular formula: C22H29F3O5S. Mole weight: 462.53. Custom synthesis is available. Send your inquiries for more information. | London |
| Afimoxifene | Afimoxifene (4-hydroxytamoxifen) is a selective estrogen receptor modulator which is the active metabolite of tamoxifen. Afimoxifene is a transdermal gel formulation and is being developed by Ascend Therapeutics, Inc. under the trademark TamoGel. Afimoxifene has completed a phase II clinical trial for the treatment of cyclical mastalgia. Uses: Estrogen antagonists. Group: Pharmaceutical. Alternative Names: (E/Z)-4-Hydroxytamoxifen; 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; TamoGel; Phenol, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-. CAS No. 68392-35-8. Pack Sizes: 100 mg. Product ID: B1370-351000. Molecular formula: C26H29NO2. Mole weight: 387.51. Custom synthesis is available. Send your inquiries for more information. | London |
| AMI-1 | AMI-1 is a cell-permeable inhibitor which inhibits protein arginine N-methyltransferase (PRMT) activity with IC50 of 8.81 μM for PRMT1 and IC50 of 3.04 μM for Hmt1p in vitro. MI-1 does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site and exhibits minimal effects on both SET (Sub39H1, Suv39H2, SET7) and non-SET (DOT1) lysine N-methyltransferases. Furthermore, AMI-1 prevents in vivo arginine methylation of cellular proteins and can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements, thus operating as a brake on certain hormone actions. Group: Pharmaceutical. Alternative Names: 7,7'-(Carbonyldiimino)bis[4-hydroxy-2-naphthalenesulfonic acid] disodium salt; 5,5'-Dihydroxy-2,2'-dinaphthylcarbamide-7,7'-disulfonic acid disodium salt; 6,6'-Ureylenebis(1-naphthol-3-sulfonic acid) disodium salt; 7,7'-Ureylenebis(4-hydroxy-2-naphthalenesulfonic acid) disodium salt; Carbonyl J disodium salt; I Acid Urea disodium salt; N,N'-Bis(5-hydroxy-7-sulfo-2-naphthyl)urea disodium salt; N,N'-Bis(7-sulfo-5-hydroxy-2-naphthyl)urea disodium salt; N,N'-Bis[1-hydroxy-3-sulfonaphthyl(6)]urea disodium salt; N,N'-Bis[1-oxy-3-sulfonaphthyl(6)]urea disodium salt; AMI-1 sodium salt; AMI 1; AMI1; J Acid Urea disodium salt. CAS No. 20324-87-2. Pack Sizes: 50 mg. Product ID: B2693-087022. Molecular formula: C21H14N2Na2O9S2. Mole weight: 548.45. Custom synthesis is available. Send your inquiries for | London |
| ARV-471 | ARV-471, an oral estrogen receptor PROTAC protein degrader for the treatment of breast cancer, is an heterobifunctional molecule that promotes the interaction between estrogen receptor alpha and intracellular E3 ligase complexes. It leads to ubiquitylation and subsequent degradation of estrogen receptors through the proteasome. In ER positive breast cancer cell lines, it has a strong ability to degrade ER with a half-maximal degradation concentration (DC50) of ~2 nM. Group: Pharmaceutical. Alternative Names: ARV471; ARV 471; (S)-3-(5-(4-((1-(4-((1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenyl)piperidin-4-yl)methyl)piperazin-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione; 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[4-[[1-[4-[(1R,2S)-1,2,3,4-tetrahydro-6-hydroxy-2-phenyl-1-naphthalenyl]phenyl]-4-piperidinyl]methyl]-1-piperazinyl]-2H-isoindol-2-yl]-, (3S)-; Vepdegestrant; (3S)-3-[1,3-Dihydro-1-oxo-5-[4-[[1-[4-[(1R,2S)-1,2,3,4-tetrahydro-6-hydroxy-2-phenyl-1-naphthalenyl]phenyl]-4-piperidinyl]methyl]-1-piperazinyl]-2H-isoindol-2-yl]-2,6-piperidinedione. CAS No. 2229711-68-4. Pack Sizes: 5 mg. Product ID: B1370-380753. Molecular formula: C45H49N5O4. Mole weight: 723.9. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD9496 | AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist. AZD9496 can induce ERα degradation in breast cancer cell lines at picomolar concentrations. Group: Pharmaceutical. Alternative Names: (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic acid; AZD9496; AZD-9496; AZD 9496. CAS No. 1639042-08-2. Pack Sizes: 25 mg. Product ID: B0084-470890. Molecular formula: C25H25F3N2O2. Mole weight: 442.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Bakuchiol | Bakuchiol is a phytoestrogen isolated from the seeds of Psoralea corylifolia L with anti-tumor, antioxidant, and antibacterial effects. Bakuchiol has a retinol-like effect on skin gene expression and properties. Bakuchiol inhibits DNA polymerase and UDP-glucuronosyltransferase 2B7 (IC50 = 41 μM). Bakuchiol has hypoglycemic, hypolipidemic, anti-inflammatory, anti-wrinkle, soothing and liver protective, anticancer, antidepressant, and estrogen-like effects. Uses: Antioxidant. Group: Pharmaceutical. Alternative Names: Drupanol; Chiba; NSC-671195; NSC671195; NSC 671195; UP-256; UP256; UP 256; W1975; W 1975; W-1975; 4-[(1E,3S)-3-Ethenyl-3,7-dimethyl-1,6-octadien-1-yl]phenol; Phenol, 4-(3-ethenyl-3,7-dimethyl-1,6-octadienyl)-, [S-(E)]-; Phenol, 4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadienyl]-; (+)-Bakuchiol; (S)-(+)-Bakuchiol; (S)-Bakuchiol; Bakutrol; Neuvachiol; Sytenol A. CAS No. 10309-37-2. Pack Sizes: 100 mg. Product ID: NP4619. Molecular formula: C18H24O. Mole weight: 256.38. Custom synthesis is available. Send your inquiries for more information. | London |
| Bavachin | Bavachin, a natural phytoestrogen found in the fruits of Psoralea corylifolia L, potentially protects cartilage from inflammation-mediated damage in joints of osteoarthritis patients through decreasing IL-1β-induced activation of IKK-IκBα-NF-κB signaling pathway. Bavachin also exhibits the activities of antioxidant, antimutagenic and weak phytoestrogen by binding and activating the estrogen receptor. Group: Pharmaceutical. Alternative Names: 4H-1-benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten -1-yl)-;7-Hydroxy-2-(4-hydroxyphenyl)-6-(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-chromen -4-one. CAS No. 19879-32-4. Pack Sizes: 50 mg. Product ID: NP1866. Molecular formula: C20H20O4. Mole weight: 324.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Bazedoxifene acetate | Bazedoxifene acetate, also called as TSE424 or WAY-140424, is a selective nonsteroidal estrogen receptor modulator (SERM) with antiosteoporotic activity (ERα: IC50= 26 nM; ERβ= 99 nM). Uses: Bone density conservation agents. Group: Pharmaceutical. Alternative Names: TSE 424; TSE-424; TSE424; WAY-140424; WAY 140424; WAY140424. CAS No. 198481-33-3. Pack Sizes: 1 g. Product ID: B2693-206133. Molecular formula: C32H38N2O5. Mole weight: 530.66. Custom synthesis is available. Send your inquiries for more information. | London |
| (-)-Catechin gallate | (-)-Catechin gallate, a minor polyphenolic constituent in green tea, is used to study its cytotoxicity. It enhances Fe(2+)-induced, lipid peroxidation. It also inhibits aromatase activity, an enzyme that converts androgens to estrogen and is thought to play a role in the etiology of breast cancer. Uses: (-)-catechin gallate has been found to be probably effective in restraining tyrosine phosphorylation caused by vegf and have potential activity in the study of breast cancer. Group: Pharmaceutical. Alternative Names: (-)-CG; (-)-Catechin gallate; (2S,3R)-2-(3,4-Dihydroxyphenyl)-3-(3,4,5-trihydroxybenzoyloxy)-3,4-dihydro-2H-1-benzopyran-5,7-diol; 3,4,5-Trihydroxybenzoic acid [[(2S)-2β-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran]-3α-yl] ester. CAS No. 130405-40-2. Pack Sizes: 25 mg. Product ID: B2703-464825. Molecular formula: C22H18O10. Mole weight: 442.37. Custom synthesis is available. Send your inquiries for more information. | London |
| Clomesone | Clomesone is a chloroethylating agent that induces the formation of cross-links between DNA strands in some cell lines and has shown antitumor activity in some animal models. It is a drug commonly used to treat female infertility and works by blocking the action of estrogen in the brain. It has been shown to be effective in inducing ovulation in women with polycystic ovary syndrome and other infertility conditions. Group: Pharmaceutical. Alternative Names: Methanesulfonic acid, 1-(methylsulfonyl)-, 2-chloroethyl ester; 2-Chloroethyl 1-(methylsulfonyl)methanesulfonate; Methanesulfonic acid, (methylsulfonyl)-, 2-chloroethyl ester; 2-Chloroethyl methanesulfonylmethanesulfonate; Chlorethyl SOSO; NSC 338947. CAS No. 88343-72-0. Pack Sizes: 1mg;1g;10g. Product ID: 88343-72-0. Molecular formula: C4H9ClO5S2. Mole weight: 236.7. Custom synthesis is available. Send your inquiries for more information. | London |
| Clomifene citrate | Clomifene Citrate is a selective estrogen receptor modulator used in the treatment of ovulation induction. It is used to treat breast cancer for its antineoplastic activity. Uses: The treatment of breast cancer. Group: Pharmaceutical. Alternative Names: NSC 35770; NSC35770; NSC-35770; CLOMIPHENE CITRATE; Zuclomiphene citrate; Clomivid; Clomphid. CAS No. 50-41-9. Pack Sizes: 50 g. Product ID: B0084-300308. Molecular formula: C26H28ClNO.C6H8O7. Mole weight: 598.08. Custom synthesis is available. Send your inquiries for more information. | London |
| Dydrogesterone | Dydrogesterone is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus. Uses: Progestational hormones, synthetic. Group: Pharmaceutical. Alternative Names: NSC 92336; NSC92336; NSC-92336. CAS No. 152-62-5. Pack Sizes: 1 g. Product ID: B0084-059548. Molecular formula: C21H28O2. Mole weight: 312.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Elacestrant | Elacestrant, also referred to RAD1901, is a selective and orally available estrogen receptor (ERR) degrader (IC50= 48 and 870 nM for ERα and ERβ, respectively) and selective estrogen receptor modulator (SERM). Group: Pharmaceutical. Alternative Names: RAD1901; RAD-1901; RAD 1901. CAS No. 722533-56-4. Pack Sizes: 100 mg. Product ID: B1370-007281. Molecular formula: C30H38N2O2. Mole weight: 458.65. Custom synthesis is available. Send your inquiries for more information. | London |
| Estradiol heptanoate | A derivative of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Uses: Estrogens. Group: Pharmaceutical. Alternative Names: Estra-1,3,5(10)-triene-3,17-diol (17β)-17-heptanoate; Estradiol-17-enanthate; 3-Hydroxyestra-1,3,5(10)-trien-17β-yl Ester Heptanoic Acid; 17-Heptanoate Estradiol. CAS No. 4956-37-0. Pack Sizes: 1mg;1g;10g. Product ID: NP3301. Molecular formula: C25H36O3. Mole weight: 384.55. Custom synthesis is available. Send your inquiries for more information. | London |
| Estradiol valerate | Estradiol valerate is a synthetic ester, specifically the 17-pentanoyl ester, of the natural estrogen, 17β-estradiol. It was introduced in the 1950s, and along with estradiol benzoate and estradiol cypionate, has since become one of the most widely used esters of estradiol. Group: Pharmaceutical. Alternative Names: Altadiol; Deladiol; Delestrogen; Estraval; Progynova; Valergen; oestradiol valerate. CAS No. 979-32-8. Pack Sizes: 1mg;1g;10g. Product ID: NP3300. Molecular formula: C23H32O3. Mole weight: 356.506. Custom synthesis is available. Send your inquiries for more information. | London |
| Estriol | Estriol is a metabolite of 17β-estradiol with much lower biological activity. It is the primary estrogen found in the urine. Large quantities of estriol and estrone are produced by the placenta during pregnancy. These are also the primary estrogens produced by adipose tissue in men and in post-menopausal women. Group: Pharmaceutical. Alternative Names: 16α-hydroxy-17β-estradiol; 1,3,5(10)-Estratriene-3,16α, 17β-triol; E3; Oestriol; Ovestin; Estratriol; Ovestrion. CAS No. 50-27-1. Pack Sizes: 20 g. Product ID: B0084-093184. Molecular formula: C18H24O3. Mole weight: 288.387. Custom synthesis is available. Send your inquiries for more information. | London |
| Estrone | Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol. Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver. Serum concentrations of estrone in premenopausal women fluctuate according to the menstral cycle and becomes the most predominant estrogen in postmenopausal women. The binding affinities of estrone to the estrogen receptors α and β are approximately 60% and 37% relative to estradiol. Group: Pharmaceutical. Alternative Names: 3-Hydroxyestra-1,3,5(10)-trien-17-one; (+)-Estrone; 1,3,5(10)-Estratrien-3-ol-17-one; 3-Hydroxy-17-keto-estra-1,3,5-triene; Aquacrine; Crinovaryl; Cristallovar; Crystogen; WAY 164397; Wynestron. CAS No. 53-16-7. Pack Sizes: 50 g. Product ID: NP6101. Molecular formula: C18H22O2. Mole weight: 270.372. Custom synthesis is available. Send your inquiries for more information. | London |
| Ethynyl estradiol | Ethinyl Estradiol is a derivative of 17β-estradiol (E2), the major endogenous estrogen in humans. EE2 is an orally bioactive estrogen used in many formulations of combined oral contraceptive pills and is one of the most commonly used medications for this purpose. Uses: Component of oral contraceptive pills. Group: Pharmaceutical. Alternative Names: Ethynyl estradiol; Ethynylestradiol; ETHINYLESTRADIOL; Ethinyloestradiol. CAS No. 57-63-6. Pack Sizes: 10 g. Product ID: NP3296. Molecular formula: C20H24O2. Mole weight: 296.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Ethynylestradiol Impurity E | An impurity of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Group: Pharmaceutical. Alternative Names: 6-alpha-Hydroxy Ethynylestradiol. CAS No. 27521-34-2. Pack Sizes: 50 mg. Product ID: B0871-231743. Molecular formula: C20H24O3. Mole weight: 312.41. Custom synthesis is available. Send your inquiries for more information. | London |
| (E/Z)-Endoxifen | One of the impurities of Tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Group: Pharmaceutical. Alternative Names: 4-Hydroxy-N-Desmethyl Tamoxifen; N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture); 4-[1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol. CAS No. 110025-28-0. Pack Sizes: 10 mg. Product ID: B2694-257357. Molecular formula: C25H27NO2. Mole weight: 373.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Formononetin | Formononetin is a phytoestrogen from the root of Astragalus membranaceus and an O-methylated isoflavone. It displays a wide variety of biological activityes, including decreasing expression of pro-imflammatory cytokines, inducing apoptosis in prostate cancer cells, lowering systolic blood pressure and inhibiting attachment and motility of Giardia. Uses: Estrogenic; antigiardial; sialidase inhibitor. Group: Pharmaceutical. Alternative Names: Formononetol, Biochanin B; Formononetol Formononetin; NSC 93360; NSC93360; NSC-93360. CAS No. 485-72-3. Pack Sizes: 5 g. Product ID: BBF-03884. Molecular formula: C16H12O4. Mole weight: 268.26. Custom synthesis is available. Send your inquiries for more information. | London |
| Fulvestrant Beta-Isomer | Fulvestrant Beta-Isomer, a drug utilized in the management of metastatic breast cancer associated with hormone receptor positivity, acts as a selective estrogen receptor down-regulator that impedes breast cancer cell growth by binding to and disintegrating estrogen receptors. Its modus operandi is to lower the expression of estrogen receptors. Group: Pharmaceutical. Alternative Names: (7β,17β)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol; Fulvestrant EP Impurity A; 7β-fulvestrant; 7beta-fulvestrant; Fulvestrant β-isomer. CAS No. 407577-53-1. Pack Sizes: 2.5 mg. Product ID: B1370-471901. Molecular formula: C32H47F5O3S. Mole weight: 606.79. Custom synthesis is available. Send your inquiries for more information. | London |
| Fulvestrant EP Impurity D | Fulvestrant EP Impurity D is an impurity of Fulvestrant, which is an estrogen receptor antagonist used as a medication indicated for the treatment of hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Group: Pharmaceutical. Alternative Names: 7,7'-Nonane-1,9-diylbis[estra-1,3,5(10)-triene-3,17β-diol]; Fulvestrant Sterol Dimer (Mixture of Diastereomers). CAS No. 2483797-59-5. Pack Sizes: 10 mg. Product ID: B1370-455513. Molecular formula: C45H64O4. Mole weight: 668.99. Custom synthesis is available. Send your inquiries for more information. | London |
| Fulvestrant Extended | Fulvestrant Extended is an impurity of Fulvestrant, an estrogen receptor antagonist used as a medication indicated for the treatment of hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Group: Pharmaceutical. Alternative Names: (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9-((9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol. Pack Sizes: 10 mg. Product ID: B2694-471906. Molecular formula: C41H65F5O4S. Mole weight: 781.09. Custom synthesis is available. Send your inquiries for more information. | London |
| Genistin | Genistin is the major isoflavonoid found in soybeans and soy products. Studies in the 1970s suggested that 99% of the isoflavonoid compounds in soy products are present as their glucosides. Genistin acts as a selective estrogen receptor modulator (SERM) and exhibits antioxidant activity and anticarcinogenic property. Uses: Antioxidant, anticarcinogenic. Group: Pharmaceutical. Alternative Names: 7-(b-D-Glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 4,5,7-Trihydroxyisoflavone 7-b-D-glucoside; Genistein-7-O-beta-D-glucopyranoside. CAS No. 529-59-9. Pack Sizes: 500 mg. Product ID: NP1903. Molecular formula: C21H20O10. Mole weight: 432.38. Custom synthesis is available. Send your inquiries for more information. | London |
| Imlunestrant | Imlunestrant, an orally active selective estrogen receptor degrader (SERD) with potential antineoplastic activity, can be used in the ER+, HER2-advanced breast cancer research. Group: Pharmaceutical. Alternative Names: LY-3484356; (R)-5-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)phenyl)-8-(trifluoromethyl)-5H-chromeno[4,3-c]quinolin-2-ol; 5H-(1)Benzopyrano(4,3-c)quinolin-2-ol, 5-(4-(2-(3-(fluoromethyl)-1-azetidinyl)ethoxy)phenyl)-8-(trifluoromethyl)-, (5R)-. CAS No. 2408840-26-4. Pack Sizes: 5 mg. Product ID: B1370-059787. Molecular formula: C29H24F4N2O3. Mole weight: 524.51. Custom synthesis is available. Send your inquiries for more information. | London |
| Isotaxiresinol | Isotaxiresinol is a natural lignan found in the branch of Taxus wallichiana. Isotaxiresinol is useful for the treatment of postmenopausal osteoporosis, especially for prevention of bone fracture induced by estrogen deficiency. Uses: Anti-cancer; anti-osteoporosis. Group: Pharmaceutical. Alternative Names: Methyl 3-bromo-2-thiophenecarboxylate. CAS No. 26194-57-0. Pack Sizes: 1 mg. Product ID: NP3924. Molecular formula: C19H22O6. Mole weight: 346.38. Custom synthesis is available. Send your inquiries for more information. | London |
| Kazinol U | Kazinol U is one estrogenic found in Broussonetia kazinoki. Kazinoki may be useful in the treatment of menopausal symptoms and may have therapeutic value in delaying pancreatic β-cell destruction in type 1 diabetes. Group: Pharmaceutical. Alternative Names: 4-[(2R)-3,4-Dihydro-7-hydroxy-2H-1-benzopyran-2-yl]-3-(3-methyl-2-buten-1-yl)-1,2-benzenediol. CAS No. 1238116-48-7. Pack Sizes: 1 mg. Product ID: NP2369. Molecular formula: C20H22O4. Mole weight: 326.39. Custom synthesis is available. Send your inquiries for more information. | London |
| Lasofoxifene | Lasofoxifene (INN) (proposed tradename Fablyn) is a non-steroidal selective estrogen receptor modulator (SERM) which is under development by Pfizer for the prevention and treatment of osteoporosis and for the treatment of vaginal atrophy, and the result of an exclusive research collaboration with Ligand Pharmaceuticals (LGND). In September 2005, Pfizer received a non-approvable letter from the U.S. Food and Drug Administration regarding lasofoxifene ( Oporia), a selective estrogen receptor modulator for the prevention of osteoporosis. Lasofoxifene was approved in the EU under the Fablyn by the EMEA in March 2009. Lasofoxifene is a desmethyl dihydro analog of nafoxidine. Group: Pharmaceutical. Alternative Names: CP 336156; CP336156; CP-336156; CP 336,156; CP336,156; CP-33,6156; Fably; Oporia. CAS No. 180916-16-9. Pack Sizes: 100 mg. Product ID: B2693-465309. Molecular formula: C28H31NO2. Mole weight: 413.561. Custom synthesis is available. Send your inquiries for more information. | London |
| Lasofoxifene tartrate | Lasofoxifene tartrate is the tartrate salt form of Lasofoxifene. Lasofoxifene is a third-generation selective estrogen receptor modulators (SERMs). Group: Pharmaceutical. Alternative Names: CP-336156; CP 336156; CP336156; (2R,3R)-2,3-dihydroxybutanedioic acid;(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol; LASOFOXIFENE HCL;(5R,6S)-5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol (2S,3S)-2,3-dihydrox. CAS No. 190791-29-8. Pack Sizes: 100 mg. Product ID: B0084-086542. Molecular formula: C28H31NO2.C4H6O6. Mole weight: 563.65. Custom synthesis is available. Send your inquiries for more information. | London |
| Liquiritigenin | Liquiritigenin is a natural flavonoid compound found in the root of Glycyrrhiza uralensis Fisch. Liquiritigenin exhibits anti-inflammatory, antihyperlipidemic and antiallergic activities. Liquiritigenin is an estrogenic compound which acts as an agonist s. Group: Pharmaceutical. Alternative Names: 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-, (2S)-; (2S)-2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-, (S)-; Flavanone, 4',7-dihydroxy-; (-)-(2S)-7,4'-Dihydroxyflavanone; (-)-(S)-4',7-Dihydroxyflavanone; (-)-Liquiritigenin; (2S)-Liquiritigenin; 4',7-Dihydroxyflavanone; 7,4'-Dihydroxyflavanone; Menerba. CAS No. 578-86-9. Pack Sizes: 20 mg. Product ID: NP2519. Molecular formula: C15H12O4. Mole weight: 256.25. Custom synthesis is available. Send your inquiries for more information. | London |
| Nafoxidine HCl | Nafoxidine HCl is the hydrochloride salt of nafoxidine. Nafoxidine, structurally related to Tamoxifen, is a non-steroidal partial estrogen antagonist. Group: Pharmaceutical. Alternative Names: 1-[2-[4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]ethyl]pyrrolidine;hydrochloride; NAFOXIDINEHYDROCHLORIDE; NafoxidineHCl; 1847-63-8; U11100A. CAS No. 1847-63-8. Pack Sizes: 1 g. Product ID: B0084-294307. Molecular formula: C29H32CINO2. Mole weight: 462.03. Custom synthesis is available. Send your inquiries for more information. | London |
| (±)-Naringenin | Naringenin is an estrogen receptor binding inhibitor produced by Streptomyces graminofaciens BA 14348. Uses: Anti-ulcer agents. Group: Pharmaceutical. Alternative Names: 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; (R,S)-Naringenin; (RS)-Naringenin; (±)-5,7,4'-Trihydroxyflavanone; 4',5,7-Trihydroxyflavanone; 5,7,4'-Trihydroxyflavanone; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chroman-4-one; 5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one; ST 057236; TCI-CA 03. CAS No. 67604-48-2. Pack Sizes: 100 g. Product ID: BBF-03516. Molecular formula: C15H12O5. Mole weight: 272.25. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Enzalutamide | N-desmethyl Enzalutamide is a major metabolite of Enzalutamide. Enzalutamide is an androgen-receptor (AR) antagonist (IC50 = 36 nM) in LNCaP cells that inhibits the transcriptional activity of a mutant AR protein. Enzalutamide resists against induction of prostate-specific antigen (PSA) and transmembrane serine protease 2 (TMPRSS2). N-desmethyl Enzalutamide can be used for the treatment of disorders involving androgen, estrogen and progesterone receptors. Uses: The treatment of disorders involving androgen, estrogen and progesterone receptors. Group: Pharmaceutical. Alternative Names: N-desmethylenzalutamide; 1242137-16-1; 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzamide; 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluorobenzamide; Enzalutamide metabolite. CAS No. 1242137-16-1. Pack Sizes: 20 mg. Product ID: B0084-474425. Molecular formula: C20H14F4N4O2S. Mole weight: 450.412. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyltamoxifen | N-Desmethyltamoxifen is a metabolite of tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Group: Pharmaceutical. Alternative Names: Desmethyltamoxifen; Tamoxifen EP Impurity F; 2-[4-[(Z)-1,2-Diphenylbut-1-en-1-yl]phenoxy]-N-methylethan-1-amine; N-Demethyltamoxifen; Demethyltamoxifen; 2-[4-[(1Z)-1,2-Diphenyl-1-butenyl]phenoxy]-N-methylethanamine; (2-(4-((1Z)-1,2-Diphenylbut-1-en-1-yl)phenoxy)ethyl)(methyl)amine; 2-[4-[(1Z)-1,2-Diphenyl-1-buten-1-yl]phenoxy]-N-methylethanamine; (Z)-2-[p-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethylamine; Tamoxifen Citrate EP Impurity F; Tamoxifen Citrate Impurity F; Tamoxifen Impurity F. CAS No. 31750-48-8. Pack Sizes: 1 g. Product ID: B1370-107540. Molecular formula: C25H27NO. Mole weight: 357.49. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Tamoxifen HCl | One of the impurities of Tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Group: Pharmaceutical. Alternative Names: (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethanamine Hydrochloride; N-Demethyltamoxifen Hydrochloride; N-Desmethyl Tamoxifen Hydrochloride. CAS No. 15917-65-4. Pack Sizes: 100 mg. Product ID: B1370-260466. Molecular formula: C25H27NO.HCl. Mole weight: 393.96. Custom synthesis is available. Send your inquiries for more information. Categories: N-DesmethylTamoxifen HCl. | London |
| Nestoron | Nestorone is a steroidal progestin of the 19-norprogesterone group which is used as a hormonal contraceptive in several South American countries. It is a potent progesterone receptor agonist with no androgenic, estrogenic, or glucocorticoid-like activities. It has been used as a female contraceptive and may be useful as a male contraceptive too recently. It does not bind to the estrogen receptor either, but it has some affinity for the glucocorticoid receptor. It appears to act as an agonist, but it does not appear to produce any glucocorticoid side effects unless used at high doses. It has been shown to have neurogenic and neuroprotective activity. It holds back proinflammatory mediators and neuropathology in the wobbler mouse model of motoneuron degeneration. It protected against hippocampus abnormalities and improved functional outcomes of EAE mice, which suggests its potential value. It lacks affinity for the androgen receptor, thus does not produce any androgenic or anabolic effects. Uses: Nestorone is used as a hormonal contraceptive in several south american countries. it has been used as a female contraceptive and may be useful as a male contraceptive too recently. it lacks affinity for the androgen receptor, thus does not produce any androgenic or anabolic effects. Group: Pharmaceutical. Alternative Names: ST-1435; ST1435; ST1435; Elcometrine; Nestorone; segesterone acetate; 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,2 | London |
| Paeoniflorin | Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin has antiandrogenic properties. Paeoniflorin inhibits the production of testosterone and promotes the activity of aromatase-the enzyme that converts testosterone into estrogen. Uses: Antiandrogenic properties. Group: Pharmaceutical. Alternative Names: 9[(Benzoyioxy)methyl]-1-(b-D-glucopyranosyloxy)-4,8-epoxy-6-methyl-7-oxaticyclo[4,3,0,0]nonane. CAS No. 23180-57-6. Pack Sizes: 500 mg. Product ID: NP4515. Molecular formula: C23H28O11. Mole weight: 480.46. Custom synthesis is available. Send your inquiries for more information. | London |
| PHTPP | PHTPP, a pyrazolo[1,5-α]pyrimidine-based ligand, is a selective estrogen ERβ receptor antagonist that displays 36-fold selectivity over ERα. This compound has been used to selectively target ERβ in the study of the opposing effects of hormone therapy on tumors expressing either ER subtype. Group: Pharmaceutical. Alternative Names: 4-[2-Phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]phenol. CAS No. 805239-56-9. Pack Sizes: 20 mg. Product ID: B0084-129603. Molecular formula: C20H11F6N3O. Mole weight: 423.31. Custom synthesis is available. Send your inquiries for more information. | London |
| Relugolix | Relugolix, also known as TAK-385, is a luteinizing hormone-releasing hormone (LH-RH) receptor antagonist administered orally. By preventing LH-RH from binding with the LH-RH receptor in the anterior pituitary gland and suppressing the secretion of luteinizing hormone (LH) and follicle stimulation hormone (FSH) from the anterior pituitary gland, TAK-385 controls the effect of LH and FSH on the ovary, reduces the level of estrogen in blood, which is known to be associated with the development of endometriosis and uterine fibroids, and is expected to improve the symptoms of these disorders. Uses: Androgen antagonists. Group: Pharmaceutical. Alternative Names: TAK-385; N-[4-[1-[(2,6-Difluorophenyl)methyl]-5-[(dimethylamino)methyl]-1,2,3,4-tetrahydro-3-(6-methoxy-3-pyridazinyl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-N'-methoxyurea; Orgovyx; RVT 601; 1-{4-[1-(2,6-difluorobenzyl)-5-dimethylaminomethyl-3-(6-methoxypyridazin-3-yl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl]phenyl}-3-methoxyurea. CAS No. 737789-87-6. Pack Sizes: 10 mg. Product ID: B0084-462794. Molecular formula: C29H27F2N7O5S. Mole weight: 623.63. Custom synthesis is available. Send your inquiries for more information. | London |
| (R)-Equol | Equol is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzein by human intestinal microflora. Group: Pharmaceutical. Alternative Names: (+)-Equol; Isoequol; (3R)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol. CAS No. 221054-79-1. Pack Sizes: 100 mg. Product ID: B1370-162728. Molecular formula: C15H14O3. Mole weight: 242.27. Custom synthesis is available. Send your inquiries for more information. | London |
| S-Deoxo Fulvestrant | S-Deoxo Fulvestrant is a derivative of Fulvestrant, an estrogen receptor antagonist used as a medication indicated for the treatment of hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Group: Pharmaceutical. Alternative Names: (7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)thio]nonyl]-estra-1,3,5(10)-triene-3,17-diol. CAS No. 153004-31-0. Pack Sizes: 1 g. Product ID: B2694-084722. Molecular formula: C32H47F5O2S. Mole weight: 590.77. Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-Equol | Equol, a metabolite of soybeans, is an important isoflavone in humans. It specifically binds to 5α-DHT, and is a high affinity estrogen receptor β ligand with a Ki of 0.73 nM. Uses: Phytoestrogens. Group: Pharmaceutical. Alternative Names: (-)-(S)-Equol; (-)-Equol; (3S)-Equol; (S)-Equol; AUS 131; (S)-3-(4-Hydroxyphenyl)chroman-7-ol; (S)-3,4-Dihydro-3-(4-Hydroxyphenyl)-2H-1-benzopyran-7-ol; (S)-(-)-4',7-Isoflavandiol; 4',7-Dihydroxyisoflavan. CAS No. 531-95-3. Pack Sizes: 100 mg. Product ID: B1370-070697. Molecular formula: C15H14O3. Mole weight: 242.27. Custom synthesis is available. Send your inquiries for more information. | London |
| Silybin A | Silymarin, isolated from the herb of Silybum marianum (L.) Gaertn, is an antioxidant or free radical scavenger. Silymarin and Prunella vulgaris improve antioxidant status in blood and liver, and positively affect plasma lipoprotein profile in an experimental model of dietary induced hypertriglyceridemia. Both in vitro and animal research suggest that Silymarin has hepatoprotective (antihepatotoxic) properties that protect liver cells against toxins. Silymarin has also demonstrated in vitro anti-cancer effects against human prostate adenocarcinoma cells, estrogen-dependent human breast carcinoma cells, human ectocervical carcinoma cells, human colon cancer cells, and both small and nonsmall human lung carcinoma cells. Silymarin treatment in type II diabetic patients for 4 months has a beneficial effect on improving the glycemic profile. Treatment with silymarin may reduce the lipoperoxidation of cell membranes and insulin resistance, significantly decreasing endogenous insulin overproduction and the need for exogenous insulin administration. Silybin is a natural compound also can be used in cosmetics material. Uses: Protective agents. Group: Pharmaceutical. Alternative Names: Silybin; 4H-1-Benzopyran-4-one, 2-[(2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-; (2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodio | London |
| Tamoxifen-[d5] | One of the labelled form of Tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Group: Pharmaceutical. Alternative Names: (Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-1,2-diphenyl-1-butene-3,3,4,4,4-d5; (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine-d5; Z-Tamoxifen-d5. CAS No. 157698-32-3. Pack Sizes: 10 mg. Product ID: BLP-013960. Molecular formula: C26H24D5NO. Mole weight: 376.56. Custom synthesis is available. Send your inquiries for more information. | London |
| trans-Clomiphene Citrate | Enclomiphene citrateis a non-steroidal estrogen receptor antagonist. It can be used for secondary hypogonadism in overweight men wishing to restore normal testicular function. Uses: Restore testicular function. Group: Pharmaceutical. Alternative Names: 2-[4-[(1E)-2-Chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethylethanamine 2-Hydroxy-1,2,3-propanetricarboxylate; (E)-Clomiphene Citrate; Clomiphene B Citrate; Enclomid; Enclomiphene Citrate; trans-Clomiphene Citrate; 15690-57-0 (free). CAS No. 7599-79-3. Pack Sizes: 2.5 mg. Product ID: B0084-476606. Molecular formula: C32H36ClNO8. Mole weight: 598.08. Custom synthesis is available. Send your inquiries for more information. | London |
| (Z)-4-Hydroxytamoxifen | (Z)-4-Hydroxytamoxifen is a metabolite of Tamoxifen and acts as an estrogen receptor antagonist. It exhibits more than 100-fold affinity over Tamoxifen. (Z)-4-Hydroxytamoxifen also activates intein-linked inactive Cas9, reducing off-target CRISPR-mediated gene editing. Group: Pharmaceutical. Alternative Names: Phenol, 4-[(1Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-; 4-[(1Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol; Phenol, 4-[(1Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]-; Phenol, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]-, (Z)-; (Z)-4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenylbut-1-en-1-yl]phenol; 4-[(1Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; 4-Hydroxy-(Z)-tamoxifen; 4-Hydroxytamoxifen; Hydroxytamoxifen; ICI 79280; trans-4-Hydroxytamoxifen; trans-Hydroxytamoxifen. CAS No. 68047-06-3. Pack Sizes: 100 mg. Product ID: B1370-096842. Molecular formula: C26H29NO2. Mole weight: 387.51. Custom synthesis is available. Send your inquiries for more information. | London |
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