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| Product | Description | |
|---|---|---|
| 1,1-Dibenzyl-4-[(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl]-1-piperidinium Bromide | Donepezil impurity. Uses: 4-[(2,3-dihydro-5,6-dimethoxy-1-oxo-1h-inden-2-yl)methyl]-1,1-bis(phenylmethyl)piperidinium is an isotope labelled impurity in the synthesis of donepezil (d531750), an inhibitor of acetylcholinesterase. Group: Pharmaceutical. CAS No. 844694-85-5. Pack Sizes: 100 mg. Product ID: B0794-470368. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 1-Methylpyridin-1-ium-2-carboxamide | 1-Methylpyridin-1-ium-2-carboxamide is an impurity of Pralidoxime Chloride, a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Group: Pharmaceutical. CAS No. 45750-74-1. Pack Sizes: 100 mg. Product ID: B0157-284893. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 1-methylpyridin-1-ium-2-carboxamide chloride | An impurity of Pralidoxime Chloride. Pralidoxime Chloride is a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Group: Pharmaceutical. CAS No. 21032-31-5. Pack Sizes: 5 mg. Product ID: B2694-338837. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 1-methylpyridin-1-ium-2-carboxamide iodide | An impurity of Pralidoxime Chloride. Pralidoxime Chloride is a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Group: Pharmaceutical. CAS No. 3861-69-6. Pack Sizes: 5 mg. Product ID: B2694-338836. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 1-methylpyridin-1-ium-2-carboxylic acid | 1-methylpyridin-1-ium-2-carboxylic acid is an impurity of Pralidoxime Chloride, a drug that binds to organophosphate-inactivated acetylcholinesterase and is used for the treatment of organophosphate poisoning. Group: Pharmaceutical. CAS No. 3697-38-9. Pack Sizes: 100 mg. Product ID: B0157-131635. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 3-Hydroxy Donepezil | 3-Hydroxy Donepezil is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Group: Pharmaceutical. CAS No. 2097683-67-3. Pack Sizes: 50 mg. Product ID: B1370-342805. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 6R,12S-Tadalafil | One of the impurities of Tadalafil, which is an inhibitor of phosphodiesterase 5 and could be used in the treatmen of erectile dysfunction. Group: Pharmaceutical. CAS No. 171596-27-3. Pack Sizes: 25 mg. Product ID: B2694-263981. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 6S,12R-Tadalafil | One of the impurities of Tadalafil, which is an inhibitor of phosphodiesterase 5 and could be used in the treatment of erectile dysfunction. Group: Pharmaceutical. CAS No. 171596-28-4. Pack Sizes: 10 mg. Product ID: B2694-263982. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 6S,12S-Tadalafil | One of the impurities of Tadalafil, which is an inhibitor of phosphodiesterase 5 and could be used in the treatmen of erectile dysfunction. Group: Pharmaceutical. CAS No. 629652-72-8. Pack Sizes: 25 mg. Product ID: B2694-263979. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AcetaMide,N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl) | 3-Acetylaminophthalic Anhydride is used in the synthesis of Apremilast, a potent phosphodiesterase 4 and tumor necrosis Factor-α inhibitor used in the treatment of psoriatic arthritis. Also a reagent in the preparation of Tillivalline. Group: Pharmaceutical. CAS No. 6296-53-3. Pack Sizes: 1mg; 1g; 10g. Product ID: 6296-53-3. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acotiamide | Acotiamide is a potent and seletive inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Group: Pharmaceutical. CAS No. 185106-16-5. Pack Sizes: 100 mg. Product ID: B0084-284892. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acotiamide-[d4] | Labelled Acotiamide. Acotiamide is a potent and selective inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003215. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acotiamide-[d6] | Labelled Acotiamide. Acotiamide is a potent and selective inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003216. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Amrinone | Amrinone is a selective cAMP phosphodiesterase (PDE-3) inhibitor with positive inotropic and vasodilatory activity. It is a simple, non-glycoside cardiotonic agent. It provides protection against ischemia-reperfusion injury in kidney, liver, and heart. It has the ability to stimulate calcium ion influx into the cardiac cell. It is used in the treatment of congestive heart failure. It increases cardiac contractility as a vasodilator. It acts by inhibiting the breakdown of both cAMP and cGMP by the phosphodiesterase (PDE3) enzyme. It is a drug that may improve the prognosis in patients with congestive heart failure. It has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). It was developed by Sanofi and has been listed. Uses: Amrinone is a simple, non-glycoside cardiotonic agent. it provides protection against ischemia-reperfusion injury in kidney, liver, and heart. it is used in the treatment of congestive heart failure. it increases cardiac contractility as a vasodilator. Group: Pharmaceutical. CAS No. 60719-84-8. Pack Sizes: 2.5 g. Product ID: B0084-072903. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Apremilast | Apremilast is an orally available small molecule inhibitor of phosphodiesterase 4 (PDE4). Apremilast specifically inhibits PDE4 and inhibits spontaneous production of TNF-alpha from human rheumatoid synovial cells. Uses: Anti-inflammatory agents, non-steroidal; phosphodiesterase inhibitors. Group: Pharmaceutical. CAS No. 608141-41-9. Pack Sizes: 5 g. Product ID: B0084-459333. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (+/-)-Apremilast | (+/-)-Apremilast is the racemic form of Apremilast, an orally available small molecule inhibitor of phosphodiesterase 4 (PDE4). Group: Pharmaceutical. CAS No. 253168-86-4. Pack Sizes: 100 mg. Product ID: B2694-006563. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Caffeine Impurity F | Paraxanthine is a metabolite of caffeine, and also acts as an inhibitor of phosphodiesterase 9 (PDE9) and an antagonist of adenosine receptors A1 and A2 (Kis = 35 and 22 μM, respectively in equine forebrain tissues). Group: Pharmaceutical. CAS No. 611-59-6. Pack Sizes: 200 mg. Product ID: B0084-129330. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Clenbuterol Impurity E | Clenbuterol Impurity E is an impurity of Clenbuterol and is used as a reagent in the synthesis of pyrazolopyridine derivatives as inhibitors of phosphodiesterase-4 (PDE-IV) and production of tumor necrosis factor-α (TNF-α). Group: Pharmaceutical. CAS No. 37148-47-3. Pack Sizes: 1 g. Product ID: B2694-469119. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CMP-Neu5,9Ac2 | CMP-Neu5,9Ac2 serves as a direct substrate of the NeuA O-acetyl esterase in vitro. Group: Pharmaceutical. CAS No. 1045785-97-4. Pack Sizes: 5 mg. Product ID: B1370-303996. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Corynoline | Corynoline, which is found in the tubers of Corydalis ambigua, is an acetylcholinesterase inhibitor. Uses: Sedative/anti-leptospira. Group: Pharmaceutical. CAS No. 18797-79-0. Pack Sizes: 25 mg. Product ID: NP0588. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Corynoxidine | Corynoxidine is an antibacterial alkaloid isolated from the roots of Stephania epigaea. Corynoxidine also acts as a dose-dependent acetylcholinesterase inhibitor. Group: Pharmaceutical. CAS No. 57906-85-1. Pack Sizes: 1 mg. Product ID: NP0804. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Demecarium bromide | Demecarium is a parasympathomimetic that acts as an acetylcholinesterase inhibitor. It is one of several topical (applied directly to the affected area) medications used to reduce elevated intraocular pressure (IOP) associated with primary glaucoma in cats, dogs, and other animals. Uses: Cholinesterase inhibitors; miotics. Group: Pharmaceutical. CAS No. 56-94-0. Pack Sizes: 500 mg. Product ID: B0084-071868. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Donepezil | Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to severe Alzheimer's disease. It readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Group: Pharmaceutical. CAS No. 120014-06-4. Pack Sizes: 50 g. Product ID: B2692-082304. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Donepezil hydrochloride | Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively. Uses: Cholinesterase inhibitors. Group: Pharmaceutical. CAS No. 120011-70-3. Pack Sizes: 100 mg. Product ID: NP3421. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Doxofylline Impurity 1 | Doxofylline Impurity 1 is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Group: Pharmaceutical. CAS No. 1429636-74-7. Pack Sizes: 100 mg. Product ID: B2694-470470. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Doxofylline Impurity 2 | Doxofylline Impurity 2 (Theophylline Impurity 2) is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Group: Pharmaceutical. CAS No. 5614-53-9. Pack Sizes: 10 mg. Product ID: B2694-470471. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ethyl diethylcarbamate | Ethyl diethylcarbamate, a carbamate derivative, finds extensive use as an alcohol denaturant and as an intermediate for the production of pesticides and pharmaceuticals. Furthermore, it exhibits potential therapeutic effects as a cholinesterase inhibitor, offering respite in the management of myasthenia gravis, a neuromuscular disorder that is typified by muscle weakness and fatigue. Group: Pharmaceutical. CAS No. 3553-80-8. Pack Sizes: 1 g. Product ID: B1370-130938. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Galantamine hydrobromide | Galantamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. It prevents β-amyloid-induced apoptosis in SH-SY5Y and bovine chromaffin cells. Uses: Nootropic agents. Group: Pharmaceutical. CAS No. 1953-4-4. Pack Sizes: 500 mg. Product ID: NP0561. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Galanthamine | Galanthamine, also called Razadyne, found in GALANTHUS and other AMARYLLIDACEAE, a cholinesterase inhibitor prescribed to treat symptoms of mild to moderate Alzheimer's, enhances cholinergic function accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Uses: Treatment of alzheimer's disease. Group: Pharmaceutical. CAS No. 357-70-0. Pack Sizes: 1 g. Product ID: B1370-343377. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Geissoschizine methyl ether | Geissoschizine methyl ether is an indole alkaloid isolated from Uncariae hooks. Geissoschizine methyl ether acts as a 5-HT7 receptor antagonist and also a potent acetylcholinesterase (AChE) inhibitor. Group: Pharmaceutical. CAS No. 60314-89-8. Pack Sizes: 5 mg. Product ID: NP0821. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gemcitabine elaidate | Gemcitabine elaidate (also known as CO-101; CP-4126) is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. Due to its lipophilicity, gemcitabine 5'-elaidic acid ester exhibits an increased cellular uptake and accumulation, resulting in an increased conversion to active metabolites, compared to gemcitabine. In addition, this formulation of gemcitabine may be less susceptible to deamination and deactivation by deoxycytidine deaminase. Group: Pharmaceutical. CAS No. 210829-30-4. Pack Sizes: 25 mg. Product ID: B2706-225221. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glabredelphinine | Glabredelphinine, a naturally occurring substance, has garnered attention for its remarkable efficacy in inducing apoptosis in tumors, thus displaying its potent anti-tumor activity. Furthermore, it has exhibited potential therapeutic benefits in the treatment of Alzheimer's disease by impeding acetylcholinesterase activity. Through its multifaceted mechanisms, Glabredelphinine represents an intriguing candidate for further exploration within both oncological and neurological research domains. Group: Pharmaceutical. CAS No. 132160-37-3. Pack Sizes: 1 mg. Product ID: NP0658. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Huperzine A | (-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 102518-79-6. Pack Sizes: 100 mg. Product ID: NP0543. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ibudilast | Ibudilast is a nonselective inhibitor of cyclic nucleotide phosphodiesterase (PDE) which has been marketed for treating asthma. It crosses the blood-brain barrier, is well tolerated, is active on oral administration, reduces glial activation and attenuates pain symptoms in diverse rat models of neuropathic pain. In addition, it enhances acute morphine analgesia and attenuates morphine tolerance and withdrawal. Thus ibudilast may improve opioid efficacy and is a promising therapeutic candidate for neuropathic pain. Group: Pharmaceutical. CAS No. 50847-11-5. Pack Sizes: 5 g. Product ID: B0084-329045. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Icatibant Acetate | Icatibant acetate is a selective antagonist of bradykinin B2 receptors. Icatibant is a medication approved for the treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. CAS No. 138614-30-9. Pack Sizes: 10 mg. Product ID: BAT-010084. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ipidacrine hydrochloride hydrate | Ipidacrine is a drug used for the treatment of memory disorders. It acts as a reversible acetylcholinesterase inhibitor. Group: Pharmaceutical. CAS No. 118499-70-0. Pack Sizes: 1 g. Product ID: B0046-013871. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Irinotecan Hydrochloride Trihydrate | The hydrochloride salt of Irinotecan. Irinotecan is a prodrug that can be activated to 7-ethyl-10-hydroxy-camptothecin (SN-38) by the carboxylesterase-converting enzyme. SN-38 inhibits topoisomerase I to suppress DNA replication and promote cell death. Group: Pharmaceutical. CAS No. 136572-09-3. Pack Sizes: 1 g. Product ID: B0084-057943. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Luteolin | Luteolin is an anti-inflammatory, antioxidant and free radical scavenger. Luteolin inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 activation. It also inhibits TNF-α-induced COX-2 expression, and phosphodiesterase with with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM for PDE1-5 respectively. It inhibits proliferation of Lewis lung carcinoma cells in vivo. Luteolin is a natural compound found in the leaves of Dracocephalum ruyschiana L. It can be used in cosmetics material. Uses: Adcs cytotoxin. Group: Pharmaceutical. CAS No. 491-70-3. Pack Sizes: 5 g. Product ID: NP1855. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Meobal-[d3] | Meobal-[d3] is a deuterium labelled Meobal, an acetylcholinesterase inhibitor used as an insecticide. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: BLP-014105. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Milrinone | Milrinone is a phosphodiesterase 3 (PDE3) inhibitor with vasodilator properties, used to increase the heart's contractility. It increases erythrocyte cAMP activity via inhibiting erythrocyte phosphodiesterase. Uses: Increase the heart's contractility. Group: Pharmaceutical. CAS No. 78415-72-2. Pack Sizes: 1 g. Product ID: B0084-291905. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mirodenafil Dihydrochloride | Mirodenafil dihydrochloride is a newly developed oral phosphodiesterase type 5 (PDE-5) inhibitor developed for the treatment of erectile dysfunction. Group: Pharmaceutical. CAS No. 862189-96-6. Pack Sizes: 500 mg. Product ID: B0084-263050. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mirodenafil Impurities | Mirodenafil Impurities hold critical importance within the biomedical sector, serving as fundamental elements in quality control and refinement of Mirodenafil, a phosphodiesterase type 5 (PDE5) inhibitor. Employed predominantly in addressing erectile dysfunction, meticulous impurity analysis guarantees therapeutic effectiveness, safety, and adherence to rigorous pharmaceutical criteria. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Neostigmine Impurities | Neostigmine Impurities, associated with the synthesis of neostigmine, play a crucial role in quality control for drugs targeting myasthenia gravis and postoperative urinary retention. These impurities help ensure the efficacy and safety of cholinesterase inhibitors by providing insights into the drug's purity and stability during pharmaceutical development. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Nobiletin | Nobiletin is a citrus flavonoid isolated from citrus peels like in tangerine, which has anti-inflammatory and anti-tumor activities. Nobiletin has anti-hemagglutination, anti-thrombosis, anti-fungal, anti-allergic, anti-cholinesterase and anti-epileptic effects. It is a carbohydrate metabolism promoter. Uses: Anticancer. Group: Pharmaceutical. CAS No. 478-01-3. Pack Sizes: 1 g. Product ID: NP1887. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Osthol | Osthole is a coumarin which is isolated from Cnidium monnieri (L.) Cusson. Osthole is a calcium channel modulator via inhibiting phosphodiesterases. It also regulates the expression of TNF-α, NF-κB, TGF-β, cyclooxygenases, leukotrienes, nitric oxide, ERK, and JNK. Osthole is a natural compound used in cosmetics material. Uses: Anti-tumor; anti-cancer; may be used as bio-pesticides. Group: Pharmaceutical. CAS No. 484-12-8. Pack Sizes: 100 g. Product ID: NP1032. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Physostigmine salicylate | Physostigmine salicylate is a cholinesterase inhibitor that can cross blood-brain barrier. It forms slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE). It has been used to improve cognitive ability and treat glaucoma. Group: Pharmaceutical. CAS No. 57-64-7. Pack Sizes: 250 mg. Product ID: B0084-028331. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Pimobendan | Pimobendan is both a calcium sensitizer and a selective inhibitor of phosphodiesterase III (PDE3) with positive inotropic and vasodilator effects. Uses: Phosphodiesterase inhibitors. Group: Pharmaceutical. CAS No. 74150-27-9. Pack Sizes: 2 g. Product ID: B0084-303517. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Polygalasaponin XXXI | Polygalasaponin XXXI is a triterpenoid compound found in the herbs of Polygala japonica Houtt. In vivo, Polygalasaponin XXXI exhibits inhibitory effect on proliferation of mouse adapted influenza virus A/PR/8/34 and cyclic AMP phosphodiesterase. Group: Pharmaceutical. CAS No. 79103-90-5. Pack Sizes: 5 mg. Product ID: B0005-053391. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rilapladib | Rilapladib is the third genomics-derived small molecule drug as a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor which is an enzyme associated with the formation of atherosclerotic plaques. Uses: 1-alkyl-2-acetylglycerophosphocholine esterase inhibitors. Group: Pharmaceutical. CAS No. 412950-08-4. Pack Sizes: 50 mg. Product ID: B1370-068407. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rivastigmine | Rivastigmine, a carbamate derivative, is a reversible cholinesterase inhibitor that is selective for the central nervous system to treat Alzheimer's Disease. Uses: Neuroprotective agents. Group: Pharmaceutical. CAS No. 123441-03-2. Pack Sizes: 10 g. Product ID: B0084-082595. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rivastigmine Impurity F | An impurity of Rivastigmine. Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Group: Pharmaceutical. CAS No. 889443-69-0. Pack Sizes: 25 mg. Product ID: B2694-479199. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rivastigmine USP Related Compound F | An impurity of Rivastigmine, a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Group: Pharmaceutical. CAS No. 1346602-84-3. Pack Sizes: 5 g. Product ID: B2694-479202. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sacubitril | Sacubitril, also known as AHU377 or LCZ696, is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume. Group: Pharmaceutical. CAS No. 149709-62-6. Pack Sizes: 10 g. Product ID: B0084-458470. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sacubitril sodium | Sacubitril, also known as AHU377, is a first-in-class medicine that contains a neprilysin (NEP) inhibitor (sacubitril) and an angiotensin II (Ang-II) receptor blocker (valsartan). Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. Group: Pharmaceutical. CAS No. 149690-05-1. Pack Sizes: 500 mg. Product ID: B0084-007864. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tacrine Impurities | Tacrine Impurities are crucial in the development and quality control of Alzheimer's disease treatments. Studying these impurities aids in enhancing the safety and efficacy of tacrine, an acetylcholinesterase inhibitor, crucial for symptom management in Alzheimer's, thus advancing therapeutic methods for neurodegenerative disorders. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tadalafil-[d3] | Tadalafil-[d3] is the labelled analogue of Tadalafil, which is an inhibitor of phosphodiesterase 5 and can be used to treat erectile dysfunction. Tadalafil is also a phosphodiesterase 5 (PDE5) inhibitor. Group: Pharmaceutical. CAS No. 960226-55-5. Pack Sizes: 10 mg. Product ID: BLP-012605. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tadalafil EP Impurity I | One of the impurities of Tadalafil, which is an inhibitor of phosphodiesterase 5 and could be used in the treatmen of erectile dysfunction. Group: Pharmaceutical. CAS No. 1795790-92-9. Pack Sizes: 10 mg. Product ID: B2694-482887. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tadalafil Impurity B | One of the impurities of Tadalafil, which is an inhibitor of phosphodiesterase 5 and could be used in the treatmen of erectile dysfunction. Group: Pharmaceutical. CAS No. 951661-82-8. Pack Sizes: 25 mg. Product ID: B2694-482858. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tadalafil Impurity D | One of the impurities of Tadalafil, which is an inhibitor of phosphodiesterase 5 and could be used in the treatmen of erectile dysfunction. Group: Pharmaceutical. CAS No. 951661-81-7. Pack Sizes: 5 mg. Product ID: B2694-482857. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Thiocholine iodide | Thiocholine iodide is an important hydrolyzed product of acetylthio-choline iodide and could be used and one of the substrates of Cholinesterase. Uses: For research used only. Group: Pharmaceutical. CAS No. 7161-73-1. Pack Sizes: 100 mg. Product ID: B0001-149809. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tolafentrine Impurities | Tolafentrine Impurities, integral to the R&D of phosphodiesterase inhibitors, offer invaluable insights into the stability, safety, and therapeutic efficacy of cardiovascular and respiratory treatments. Their study aids in refining drug formulations, enhancing the efficacy of therapies targeting asthma and chronic obstructive pulmonary disease, ultimately advancing pharmacological innovation. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Vasicil | Vasicinol, which usually comes from the leaves of Adhatoda vasica Nees, shows a high sucrase inhibitory activity with IC50 value of 250 μM. It could be used to treat metabolic disorders. It also can be used as a transient hypotensive agent, cardiac depressant and histamine antagonist. Vasicinol shows mild anticholinesterase activity. Uses: Anticholinesterase. Group: Pharmaceutical. CAS No. 5081-51-6. Pack Sizes: 1 mg. Product ID: NP0004. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Vinpocetine | Vinpocetine is a Phosphodiesterase inhibitor and selective for PDE1. It also blocks voltage-gated Na+ channels. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 42971-09-5. Pack Sizes: 500 mg. Product ID: B0046-464044. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| XMC-[d3] | XMC-[d3] is a deuterium labelled 3,5-Xylyl methylcarbamate, an acetylcholinesterase inhibitor used as an insecticide. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: BLP-014106. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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