Find where to buy products from UK suppliers, including: distributors, industrial manufacturers, wholesalers, raw ingredients, bulk supplies and finished goods for sale.
Search for products or services, then visit the suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the USA.
| Product | Description | |
|---|---|---|
| CMP-Neu5,9Ac2 | CMP-Neu5,9Ac2 serves as a direct substrate of the NeuA O-acetyl esterase in vitro. Group: Pharmaceutical. CAS No. 1045785-97-4. Pack Sizes: 5 mg. Product ID: B1370-303996. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Gemcitabine elaidate | Gemcitabine elaidate (also known as CO-101; CP-4126) is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. Due to its lipophilicity, gemcitabine 5'-elaidic acid ester exhibits an increased cellular uptake and accumulation, resulting in an increased conversion to active metabolites, compared to gemcitabine. In addition, this formulation of gemcitabine may be less susceptible to deamination and deactivation by deoxycytidine deaminase. Group: Pharmaceutical. CAS No. 210829-30-4. Pack Sizes: 25 mg. Product ID: B2706-225221. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Icatibant Acetate | Icatibant acetate is a selective antagonist of bradykinin B2 receptors. Icatibant is a medication approved for the treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. CAS No. 138614-30-9. Pack Sizes: 10 mg. Product ID: BAT-010084. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rilapladib | Rilapladib is the third genomics-derived small molecule drug as a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor which is an enzyme associated with the formation of atherosclerotic plaques. Uses: 1-alkyl-2-acetylglycerophosphocholine esterase inhibitors. Group: Pharmaceutical. CAS No. 412950-08-4. Pack Sizes: 50 mg. Product ID: B1370-068407. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sacubitril | Sacubitril, also known as AHU377 or LCZ696, is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume. Group: Pharmaceutical. CAS No. 149709-62-6. Pack Sizes: 10 g. Product ID: B0084-458470. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sacubitril sodium | Sacubitril, also known as AHU377, is a first-in-class medicine that contains a neprilysin (NEP) inhibitor (sacubitril) and an angiotensin II (Ang-II) receptor blocker (valsartan). Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. Group: Pharmaceutical. CAS No. 149690-05-1. Pack Sizes: 500 mg. Product ID: B0084-007864. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
Our database is helping our users find suppliers everyday.
