Find where to buy products from UK suppliers, including: distributors, industrial manufacturers, wholesalers, raw ingredients, bulk supplies and finished goods for sale.
Search for products or services, then visit the suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the USA.
| Product | Description | |
|---|---|---|
| 3-(Methylseleno)-L-alanine | 3-(Methylseleno)-L-alanine, a metabolite found in Escherichia coli (strain K12, MG1655), is an inhibitor of DMBA-induced mammary tumors. It has oral bioavailability and can induce cell apoptosis. Group: Pharmaceutical. CAS No. 26046-90-2. Pack Sizes: 1 g. Product ID: BBF-05851. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 4-thiouridine | Nucleotide analogue is essential to cell growth in certain bacterial species, which is also able to chelate with certain metal ions, and in tRNA. It can act as a built-in antiphotomutagenic agent protecting Escherichia coli cells against mutagenesis. Uses: Affinity labels. Group: Pharmaceutical. CAS No. 13957-31-8. Pack Sizes: 1 g. Product ID: B2706-009850. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Actinamine Dihydrochloride | Actinamine dihydrochloride is an impurity of Spectinomycin (HCl salt-S680250), an antibiotic that selectively inhibits protein synthesis in cells of Escherichia coli, and is also commonly used to treat patients with uncomplicated cases of gonorrhea. Group: Pharmaceutical. CAS No. 52049-70-4. Pack Sizes: 1mg; 1g; 10g. Product ID: BB075375. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CHIR-090 | CHIR-090 is a very potent and tight-binding inhibitor of LpxC, which is a zinc-dependent amidase and present in almost all Gram-negative bacteria, and is a promising target for the development of novel antibiotic substances against multigrug-resistant Gram-negative bacteria. Its Ki value is 4.0 nM. It displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin. It has a different selectivity with the reported LpxC inhibitor L-161. It has excellent antibiotic activity against Pseudomonas aeruginosa and Escherichia coli by inhibiting LpxC orthologs at low nM concentrations. It is an excellent lead for the further development of new antibiotics targeting the lipid A pathway. Uses: Chir-090 displays two-step time-dependent inhibition and kills a wide range of gram-negative pathogens as effectively as ciprofloxacin or tobramycin. it has excellent antibiotic activity against pseudomonas aeruginosa and escherichia coli by inhibiting lpxc orthologs at low nm concentrations. Group: Pharmaceutical. CAS No. 728865-23-4. Pack Sizes: 300 mg. Product ID: B0084-474822. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Emodin anthrone | Emodin anthrone is a natural product found in Rhamnus prinoides, Paeonia emodi, and Rumex acetosa with data available. Emodinanthrone inhibits respiration-driven solute transport at micromolar concentrations in membrane vesicles of Escherichia coli. Group: Pharmaceutical. CAS No. 491-60-1. Pack Sizes: 1 g. Product ID: B0001-093033. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ertapenem Sodium | Ertapenem Sodium is the sodium salt of ertapenem. Ertapenem has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of ertapenem results from the inhibition of cell wall synthesis and is mediated through ertapenem binding to penicillin binding proteins (PBPs). In Escherichia coli, it has strong affinity toward PBPs 1a, 1b, 2, 3, 4 and 5 with preference for PBPs 2 and 3. Ertapenem is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases. Ertapenem is hydrolyzed by metallo-beta-lactamases. Ertapenem has been shown to be active against most isolates of the following microorganisms in vitro and in clinical infections. Group: Pharmaceutical. CAS No. 153773-82-1. Pack Sizes: 1 g. Product ID: BBF-03993. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isocytidine | An isomer of Cytidine, a constituent of nucleic acid. It is converted to isocytosine and uracil during metabolism in Escherichia coli. Group: Pharmaceutical. CAS No. 489-59-8. Pack Sizes: 50 mg. Product ID: B1370-277261. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Linezolid | Linezolid inhibits initiation complex formation with either the 30S or the 70S ribosomal subunits from Escherichia coli. Linezolid is a synthetic oxazolidinone antibiotic active against a wide range of Gram-positive bacteria, including resistant strains of several species, such as MRSA and penicillin-resistant pneumococci. Group: Pharmaceutical. CAS No. 165800-03-3. Pack Sizes: 50 mg. Product ID: BBF-04161. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Linezolid Impurity 42 | An impurity of Linezolid. Linezolid inhibits initiation complex formation with either the 30S or the 70S ribosomal subunits from Escherichia coli. Group: Pharmaceutical. CAS No. 725676-93-7. Pack Sizes: 10 mg. Product ID: B2694-338786. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Linezolid Impurity 44 | An impurity of Linezolid. Linezolid inhibits initiation complex formation with either the 30S or the 70S ribosomal subunits from Escherichia coli. Group: Pharmaceutical. CAS No. 183805-10-9. Pack Sizes: 2 mg. Product ID: B2694-338787. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Menaquinone 7 | Menaquinone 7 is a form of vitamin K2, which includes nine related compounds. Menaquinone 7 is a long-chain menaquinone that is synthesized by Escherichia coli bacteria in the gut. It can be used as a supplement for bone health. Menaquinone 7 can be used as vitamin supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 2124-57-4. Pack Sizes: 20 mg. Product ID: BBF-05784. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Pachyaximine A | Pachyaximine A, isolated from the herbs of Pachysandra axillaris, possesses significant antibacterial activity against Escherichia coli, Staphylococcus aureus, Corynebacterium diphtheriae and Corynebacterium pyrogenes. Uses: Antibacterial; antimicrobial. Group: Pharmaceutical. CAS No. 128255-08-3. Pack Sizes: 5 mg. Product ID: NP0286. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tretazicar | Tretazicar (CB1954) is a dinitrobenzamide prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide (EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. CB1954 has been proposed for use in enzyme-prodrug gene therapy systems with the Escherichia coli enzyme nitroreductase (Ntr). Ntr converts CB1954 to 2- and 4-hydroxylamino derivatives, whereupon the non-enzymatic reaction of the 4-hydroxylamino derivative with cellular thio- esters generates a potent cytotoxic bifunctional alkylating agent capable of cross-linking DNA. Ntr delivery has been achieved in vitro using retroviral and adenoviral vectors and confirmed by immunocytochemical demonstration of Ntr expression. The Ntr-expressing cells have been shown to be sensitized to CB1954 by up to 2000-fold. The Ntr-CB1954 system shows effective bystander killing in mixed populations of Ntr-expressing and non-expressing cells treated with CB1954. The efficacy of this enzyme-prodrug approach in model systems compared with other VDEPT approaches demonstrates the feasibility and future promise of this gene therapy strategy. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 21919-05-1. Pack Sizes: 1 g. Product ID: B2693-366889. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
Our database is helping our users find suppliers everyday.
