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Epieriocalyxin A Epieriocalyxin A (EpiA), a diterpenoid isolated from I. eriocalyx, suppressed Caco-2 colon cancer cell growth. Western blot results showed that both JNK and ERK1/2 activation was decreased after Epieriocalyxin A treatment in a dose-dependent manner. Epieriocalyxin A increased the expression of caspase 3 and Bax, and decreased Bcl2 expression. Our results suggest that Epieriocalyxin A is a novel compound that induces colon cancer apoptosis. Epieriocalyxin A could be a potential drug for colon cancer therapy in the future. Uses: Anti-cancer. Group: Pharmaceutical. Alternative Names: Spiro[1H-7,9a-methanolocyclohepta[c]pyran-4(3H),1'-[3]cyclohexene]-6'-carboxaldehyde, 4a,5,6,7,8,9-hexahydro-5',5',8-trimethyl-1,2',9-trioxo-, (1'S,4aS,6'R,7R,8R,9aS)-. CAS No. 191545-24-1. Pack Sizes: 1 mg. Product ID: NP1352. Molecular formula: C20H24O5. Mole weight: 344.4. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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