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| Product | Description | |
|---|---|---|
| 1-(2,2,2-Trifluoro-N-phenylethanimidate)-2,3,4-tri-O-acetyl-D-glucopyranuronic acid methyl ester | 1-(2,2,2-Trifluoro-N-phenylethanimidate)-2,3,4-tri-O-acetyl-D-glucopyranuronic acid methyl ester is a profoundly efficacious and multifaceted biomedical compound. With an intricate mode of action, it selectively interacts with targeted receptors and enzymes, effectively ameliorating the symptoms associated with inflammation, pain, and allergic responses. Group: Pharmaceutical. CAS No. 869996-05-4. Pack Sizes: 100 mg. Product ID: B1370-000042. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 16-Hydroxycleroda-3,13-dien-15,16-olide | 16-Hydroxycleroda-3,13-dien-15,16-olide is extracted from the unripe fruits of Polyalthia longifolia var. pendula. It is used as a candidate for autophagy inducers which can cause cell death in an alternative or supplement medicine for cancer therapy. It displays promising NO inhibitory activity at 10 ug/mL and shows anti-inflammatory activity. It induces apoptosis in CML K562 cells and regulates the expression of histone-modifying enzymes PRC2 complex. Group: Pharmaceutical. CAS No. 141979-19-3. Pack Sizes: 1 mg. Product ID: NP1411. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 16-Oxolyclanitin-29-yl p-coumarate | 16-Oxolyclanitin-29-yl p-coumarate is a highly intriguing natural compound within the biomedical industry. By selectively targeting distinct molecular pathways, this product effectively studys diverse ailments. Its profound impact is observed through the potent inhibition of enzymes and receptors implicated in the advancement of various cancer types and inflammatory afflictions. Group: Pharmaceutical. CAS No. 140701-70-8. Pack Sizes: 1 mg. Product ID: NP7115. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 1-Butyl-2-{[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino}-7-methoxy-1H-benzimidazole-5-carboxamide | 1H-benzimidazole-5-carboxamide, scientifically known as 1-Butyl-2-{[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino}-7-methoxy, exhibits tremendous potential as an anti-cancer agent. This drug operates by impeding the growth of malignant tumors through the inhibition of enzymes engaged in cell division and DNA replication. This intricate mechanism of action has proven to be successful in the treatment of colon, lung, and breast cancer, and offers promising possibilities for cancer therapy. Group: Pharmaceutical. CAS No. 2137975-08-5. Pack Sizes: 5 mg. Product ID: B0001-260292. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2,5-dioxopyrrolidin-1-yl 4-methyl-4-((5-nitropyridin-2-yl)disulfanyl)pentanoate | NO2-SPDMV is a biomedical product used in the drug development of various diseases. With its unique chemical structure, it exhibits potential therapeutic properties to target specific receptors and enzymes involved in the progression of certain disorders. Its applications include drug research to treat cardiovascular disease, neurological diseases, and inflammatory diseases, among others. Group: Pharmaceutical. CAS No. 663598-98-9. Pack Sizes: 10 mg. Product ID: BADC-00466. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2,6-Dichloromethylpyridine hydrochloride | 2,6-Dichloromethylpyridine hydrochloride, a chemical compund extensively utilized in biomedical research, exhibits great potential in developing effective therapeutics for a range of serious ailments, including cancer, Alzheimer's disease, and Parkinson's disease. Its potential as a drug candidate lies in its remarkable ability to powerfully inhibit critical enzymes closely linked to the pathogenesis of these disorders. This subtle but significant biological effect offers a new therapeutic option in the pursuit of enhanced patient outcomes. Group: Pharmaceutical. CAS No. 55422-79-2. Pack Sizes: 50 g. Product ID: B0001-071475. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2,9-Dibromo-1,10-Phenanthroline | 2,9-Dibromo-1,10-Phenanthroline, a heterocyclic aromatic compound comprising two fused six-membered rings, is an indispensable element in the field of biomedical research due to its unique properties. With its proficient nature, this compound provides a remarkable breakthrough in detecting and quantifying a wide range of metal ions. Its chelating activity along with its potential inhibitory effect towards metal-dependent enzymes makes it a valuable tool for a diverse range of laboratory applications. Further, with its exceptional medicinal properties, it plays a pivotal role in developing drugs to combat complex and multifactorial diseases such as cancer and Alzheimer's, highlighting the remarkable impact of this compound in the biomedical field. Group: Pharmaceutical. CAS No. 39069-02-8. Pack Sizes: 5 g. Product ID: B2699-179946. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Bromo-1-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)ethanone | 2-Bromo-1-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)ethanone, a promising small molecule inhibitor, holds tremendous potential for use in biomedical research towards terminal selectivity of enzymes or pathologies. Nevertheless, the paucity of available information concerning this compound hampers its functional applications in diverse biological contexts. Group: Pharmaceutical. CAS No. 1056050-24-8. Pack Sizes: 500 mg. Product ID: B2699-128594. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2'-Deoxyuridine-5'-triphosphate trisodium salt | dUTP is a deoxynucleoside triphosphate (dNTP) that acts as a substrate for several enzymes. It can be used in PCR and qPCR. Group: Pharmaceutical. CAS No. 102814-08-4. Pack Sizes: 500 mg. Product ID: B1370-081015. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| [2-(Methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide | [2-(Methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide, an innovative pharmaceutical compound, plays a pivotal role in addressing a myriad of diseases by selectively modulating intricate cellular mechanisms. As an effective antagonist of key enzymes involved in the pathogenesis of malignant tumors, it is widely used in antimicrobial drug development. Group: Pharmaceutical. CAS No. 3637-26-1. Pack Sizes: 1 kg. Product ID: B1370-091081. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 3-Carboxy-proxyl | 3-Carboxy-proxyl - a remarkably stable nitroxide radical that serves as a spin-label in electronic paramagnetic resonance (EPR) spectroscopy. Boasting wide-ranging applications in biosciences, 3-Carboxy-proxyl has been extensively utilized for scrutiny of an assortment of biological systems, comprising enzymes, membrane proteins, and DNA. Moreover, its potential therapeutic applications, including the treatment of neurological disorders like stroke and neurodegenerative diseases, have been the focus of extensive analysis. Group: Pharmaceutical. CAS No. 2154-68-9. Pack Sizes: 5 g. Product ID: B2699-187805. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 4-methyltetrahydro-2H-pyran-2-one | 4-methyltetrahydro-2H-pyran-2-one, a chemical compound extensively utilized in the pharmaceutical industry, exhibits potential for therapeutic effects in various conditions. These conditions include, among others, inflammation, Alzheimer's disease, and cancer. Due to its capacity to modulate specific enzymes and receptors involved in these conditions, it holds enormous promise as a drug development candidate. Group: Pharmaceutical. CAS No. 1121-84-2. Pack Sizes: 5 g. Product ID: B0001-314586. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 4-(N-Phenylamidino)thiazole hydrochloride | 4-(N-Phenylamidino)thiazole hydrochloride, a chemical compound with potential therapeutic benefits, has been investigated for its ability to target specific enzymes involved in the replication of cancer cells and viruses. Extensive research has been conducted on this compound through both in vitro and in vivo models, with preclinical studies indicating promising results. However, further inquiry is needed to fully comprehend its potential applications in the biomedical industry. Group: Pharmaceutical. CAS No. 13631-64-6. Pack Sizes: 100 mg. Product ID: B1370-083565. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Carboxytetramethylrhodamine succinimidyl ester | 5-Carboxytetramethylrhodamine succinimidyl ester is an amine-reactive, orange-fluorescent dye used for labeling DNA and RNA. It also has been used to create bioconjugates with peptides, proteins and enzymes. Group: Pharmaceutical. CAS No. 150810-68-7. Pack Sizes: 250 mg. Product ID: B0001-331300. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Hydroxymethyldeoxyuridylate | 5-Hydroxymethyldeoxyuridylate is a pivotal nucleotide in DNA bioresearch and repair, emerging as a substrate indispensable for diverse enzymes implicated in DNA methylation and demethylation cascades. Group: Pharmaceutical. CAS No. 5238-86-8. Pack Sizes: 10 mg. Product ID: B1370-376869. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 6-Methylchrysene | 6-Methylchrysene, a polycyclic aromatic hydrocarbon, has been postulated as a potential carcinogen and may increase the likelihood of developing lung and skin cancer. Due to its carcinogenic properties, this compound is commonly employed in research to investigate the health risks posed by PAH and examine measures to mitigate such threats. Further studies indicate that catabolism of 6-Methylchrysene by enzymes CYP1A1 and CYP1B1 produces deleterious metabolites, implying that these enzymes could possibly contribute to the development of specific cancers. The intricate relationship between 6-Methylchrysene and cancer has encouraged extensive research to comprehend the mechanisms by which it adversely affects human health. Group: Pharmaceutical. CAS No. 1705-85-7. Pack Sizes: 10 mg. Product ID: B0001-085628. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 9-ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile | 9-Ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile, a promising therapeutic agent for the treatment of select neoplastic disorders, functions as a highly proficient suppressor of pathogenic kinase enzymes that exhibit heightened expression levels in malignant neoplastic cells. This mechanism of action, whereby key cellular signaling pathways are disrupted, culminates in the prevention of tumor growth and impairs the metastatic process. Group: Pharmaceutical. CAS No. 1256584-80-1. Pack Sizes: 100 mg. Product ID: B2699-281515. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aaf-Arg-OH HCl | Aaf-Arg-OH HCl, a substrate of carboxypeptidase B-type enzymes, has been used to determine the activation of TAFI (thrombin activatable fibrinolysis inhibitor, carboxypeptidase U) by thrombin and thrombin-thrombomodulin. Group: Pharmaceutical. CAS No. 442158-31-8. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015297. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Abametapir-[d6] | Abametapir-[d6] is an isotopic labelled of Abametapir. Abametapir is the active ingredient of Xeglyze Lotion. Abametapir inhibits metalloproteinases, enzymes that are essential to physiological processes critical for egg development and the survival of nymph and adult lice. Group: Pharmaceutical. CAS No. 1803416-92-3. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003174. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acaterin | Acarbose is an acyl-CoA isolated from Pseudomonas species. A92. In the presence of oxidized low-density lipoprotein in macrophages J744, the synthesis of cholesterol enzymes is inhibited, with an IC50 of 45 μmol/L, and the IC50 for inhibiting ACAT in rat liver microsomes is 120 μmol/L. Inhibition of ACAT is non-competitive Sexual. Group: Pharmaceutical. CAS No. 144398-20-9. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-00539. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Alectinib | Alectinib, marketed as Alecensa, is an oral drug that blocks the activity of anaplastic lymphoma kinase (ALK) and is used to treat non-small-cell lung cancer (NSCLC). Alectinib has a low potential for interactions. While it is metabolised by the liver enzyme CYP3A4, and blockers of this enzyme accordingly increase its concentrations in the body, they also decrease concentrations of the active metabolite M4, resulting in only a small overall effect. Conversely, CYP3A4 inducers decrease alectinib concentrations and increase M4 concentrations. Interactions via other CYP enzymes and transporter proteins cannot be excluded but are unlikely to be of clinical significance. Group: Pharmaceutical. CAS No. 1256580-46-7. Pack Sizes: 200 mg. Product ID: B0084-454466. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Belinostat | Belinostat is a hydroxamic acid-type histone deacetylase (HDAC) inhibitor. Belinostat targets HDAC enzymes to inhibit tumor cell proliferation and angiogenesis, induce apoptosis and promote cellular differentiation. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 414864-00-9. Pack Sizes: 100 mg. Product ID: B0084-141764. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Benzamide, N-[4-methyl-3-[[4-(6-methyl-3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-[(4-methyl-1-piperazinyl)methyl]- | This product is a kinase inhibitor used in the treatment of certain types of cancer, including non-small cell lung cancer and pancreatic cancer. It works by inhibiting specific enzymes involved in cell growth and proliferation, ultimately leading to tumor regression. Group: Pharmaceutical. CAS No. 1032314-85-4. Pack Sizes: 10 mg. Product ID: B2699-456548. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bestatin Impurities | Bestatin Impurities are critical in the biomedical industry for quality control during the production of Bestatin, a known inhibitor of aminopeptidase enzymes. These impurities help ensure the drug's efficacy and safety in treating various cancers and as an adjunct therapy for enhancing immune response against infections. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| β-Nicotinamide Adenine Dinucleotide | NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It plays a role in the activity of several enzymes, such as poly(ADP)-ribose polymerases and cADP-ribose synthases. NAD+ is commonly used as an oxidizing agent. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 53-84-9. Pack Sizes: 10 g. Product ID: B0084-094034. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| β-pseudoUridine | An isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. It is formed by enzymes called synthases, which post-transcriptionally isomerize specific uridine residues in RNA in a process termed pseudouridylation. Studies suggest that Beta-Pseudouridine reduces radiation-induced chromosome aberrations in human lymphocytes. Group: Pharmaceutical. CAS No. 1445-07-4. Pack Sizes: 5 g. Product ID: BBF-04654. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BIS(1-BUTYLPENTYL) DECANE-1,10-DIYL DIGLUTARATE | Abbreviated as Sec or U, in older publications also as Se-Cys, as a building block of selenoproteins, this 21st proteinogenic amino acid exists naturally in three domains of life, but not in every lineage. Uses: Used for the characterization of total sodium concentration in human blood plasma; also used for the preparation of nitrite-selective membrane electrode, used for the potentiometric determination of nad(p)h coenzymes. Group: Pharmaceutical. CAS No. 101342-76-1. Pack Sizes: 1 g. Product ID: B0001-236189. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| bis-(4-(1,1,3,3-Tetramethylbutyl)phenyl) ether | Bis-(4-(1,1,3,3-Tetramethylbutyl)phenyl) ether is a highly valuable compound for the pharmaceutical industry due to its significance as a key intermediate. The synthesis of drugs and compounds for the treatment of a myriad of diseases depends on the use of bis-(4-(1,1,3,3-Tetramethylbutyl)phenyl) ether. Its versatility lies in its utilization as a crucial material in developing anti-inflammatory, antiviral agents, and inhibition of enzymes and receptors. The incorporation of this compound in drug formulations has immense implications for the healthcare industry. Group: Pharmaceutical. CAS No. 101-58-6. Pack Sizes: 10 mg. Product ID: B2699-273506. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Camostat Mesylate | Camostat (INN) or FOY-305 is a serine protease inhibitor. Serine protease enzymes have a variety of functions in the body, and so camostat has a diverse range of uses. It is used in the treatment of some forms of cancer and is also effective against some viral infections, as well as inhibiting fibrosis in liver or kidney disease orpancreatitis. Uses: Trypsin inhibitors. Group: Pharmaceutical. CAS No. 59721-29-8. Pack Sizes: 5 g. Product ID: B2693-072632. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Carmustine | Carmustine is antineoplastic nitrosourea. Carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. This agent also carbamoylates proteins, including DNA repair enzymes, resulting in an enhanced cytotoxic effect. Carmustine is highly lipophilic and crosses the blood-brain barrier readily. It is used in the treatment of brain tumors, multiple myeloma and some lymphomas. Group: Pharmaceutical. CAS No. 154-93-8. Pack Sizes: 5 g. Product ID: B2693-465289. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chondroitin disaccharide di-0S sodium salt | It is produced by various chondroitin sulfates through the action of chondroitin enzymes ABC, AC-1 and C. Group: Pharmaceutical. CAS No. 136132-69-9. Pack Sizes: 5 mg. Product ID: B1370-211573. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cidofovir dihydrate | Cidofovir is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription. It is an acyclic nucleoside phosphonate, and is therefore independent of phosphorylation by viral enzymes, unlike acyclovir. Cidofovir was discovered at the Institute of Organic Chemistry and Biochemistry, Prague, and developed by Gilead Sciences and is marketed with the brand name Vistide by Gilead in the USA, and by Pfizer elsewhere. Maintenance therapy with cidofovir involves an infusion only once every two weeks, making it a convenient treatment option. Because dosing is relatively infrequent, a permanent catheter is not necessary for infusions. Uses: Antiviral agents. Group: Pharmaceutical. CAS No. 149394-66-1. Pack Sizes: 250 mg. Product ID: BBF-03991. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cobicistat | Cobicistat is a potent inhibitor of cytochrome P450 3A enzymes, including the important CYP3A4 subtype. It also inhibits intestinal transport proteins, increasing the overall absorption of several HIV medications, including atazanavir, darunavir and tenofovir alafenamide fumarate. Uses: Anti-hiv agents. Group: Pharmaceutical. CAS No. 1004316-88-4. Pack Sizes: 25 mg. Product ID: B0084-456314. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CUDA | CUDA is an inhibitor of soluble epoxide hydrolase (sEH) which catalyzes the conversion of EETs to the corresponding dihydroxy eicosatrienoic acids (DiHETrEs; DHETs) thereby diminishing their activity with IC50 values of 11.1 nM and 112 nM for the mouse and human enzymes, respectively. Group: Pharmaceutical. CAS No. 479413-68-8. Pack Sizes: 25 mg. Product ID: B2693-251168. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| D-erythro-Sphingosine | D-erythro-Sphingosine is a natural isomer of sphingosine and acts as an inhibitor of protein kinase C and calmodulin-dependent enzymes with no effects on protein kinase A or myosin light chain kinase. It may stimulate mast cells by activation of protein kinase C. Group: Pharmaceutical. CAS No. 123-78-4. Pack Sizes: 250 mg. Product ID: B2693-162633. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| D-Glucose-6-phosphate dipotassium salt trihydrate | D-Glucose-6-phosphate dipotassium salt trihydrate is a pivotal compound extensively employed in the biomedical research and pharmaceutical industry, unveiling noteworthy potential in investigating intricate metabolic disorders and glucose metabolism. This paramount product seamlessly acts as a substrate for a diverse array of enzymes, facilitating the meticulous identification and characterization of pertinent pathways germane to therapeutic drug development of afflictions such as diabetes and glycogen storage diseases. Group: Pharmaceutical. CAS No. 207727-36-4. Pack Sizes: 250 mg. Product ID: B2705-101654. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Diosgenin | Diosgenin, a steroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted from the tubers of Dioscorea wild yam, such as the Kokoro. The sugar-free (aglycone), diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and other steroid products. Diosgenin is an important medicine for the treatment of cardiovascular diseases, leukemia, encephalitis, skin diseases and tumors. Uses: Anti-inflammatory and anticancer. Group: Pharmaceutical. CAS No. 512-04-9. Pack Sizes: 250 g. Product ID: NP6077. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Dnp-Pro-Leu-Gly-Leu-Trp-Ala-DArg-NH2 | Dnp-Pro-Leu-Gly-Leu-Trp-Ala-DArg-NH2, a peptide utilized for biological research, is an exemplary agent for evaluating proteolytic activity and inhibitor effects. Notably, its potential in disease treatment, encompassing cancer and inflammation, has put it at the forefront of therapeutic development. In addition to its promising therapeutic properties, Dnp-Pro-Leu-Gly-Leu-Trp-Ala-DArg-NH2 may serve as a vital diagnostic tool for identifying pertinent enzymes within biological samples, providing otherwise unattainable insights for investigative purposes. Group: Pharmaceutical. CAS No. 121282-17-5. Pack Sizes: 10 mg. Product ID: BAT-006194. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ebselen | Ebselen, also known as SPI-1005, is an organoselenium compound with potential anti-oxidant, anti-inflammatory and cytoprotective activity. Upon oral administration of SPI-1005, this agent mimics the activity of glutathione peroxidase (GPx) and can utilize glutathione to reduce other unstable molecules, thus preventing the formation of reactive oxygen species (ROS) and reducing oxidative stress on the cell. In the cochlea, this agent may prevent drug-induced injury to the auditory hair cells thereby preventing hearing loss. GPx is the main antioxidant enzyme in the cochlea and protects the inner ear from loud sounds and biochemical damage. In addition, ebselen is able to inhibit the activity of many enzymes involved in inflammation. Group: Pharmaceutical. CAS No. 60940-34-3. Pack Sizes: 1 g. Product ID: B2693-072972. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Elacridar | Elacridar hydrochloride (GF120918A) is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. In vitro, GF120918A demonstrated high plasma protein binding across species, although a definitive protein binding evaluation was precluded by poor recovery, particularly in buffer and in mouse, rat, and dog plasma. GF120918A did not demonstrate potent inhibition of several human cytochrome P450 enzymes evaluated in vitro, with IC(50) values well above concentrations anticipated to be achieved in vivo. Together, these data confirm the utility of GF120918A as a tool P-glycoprotein inhibitor in preclinical species and offer additional guidance on preclinical dose regimens likely to produce P-glycoprotein-mediated effects. Group: Pharmaceutical. CAS No. 143664-11-3. Pack Sizes: 100 mg. Product ID: B0084-311800. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ethyl b-D-thioglucopyranoside | Ethyl b-D-thioglucopyranoside is a valuable chemical compound acting as an inhibitor for enzymes involved in carbohydrate metabolism. Additionally, it is employed in the synthesis of biologically active molecules, specifically designed to study diseases related to carbohydrate metabolism, such as diabetes and metabolic disorders. Group: Pharmaceutical. CAS No. 7473-36-1. Pack Sizes: 5 g. Product ID: B2705-097910. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Fmoc-Thr[GalNAc(Ac)3-α-D]-OH | Fmoc-Thr[GalNAc(Ac)3-α-D]-OH is a biomedical compound used for the research of diseases involving abnormal glycosylation processes. It functions as a glycosylation inhibitor, targeting enzymes responsible for glycan modification. This product aids in the study and understanding of glycosylation-related disorders. Group: Pharmaceutical. CAS No. 116783-35-8. Pack Sizes: 25 mg. Product ID: BAT-008014. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Garbanzol | Garbanzol, a revolutionary therapeutic agent with mighty anti-inflammatory properties, proffers a potential cure for a myriad of inflammatory ailments. Counted among them are rheumatoid arthritis, psoriasis, and inflammatory bowel disease. By constraining vital enzymes linked with inflammation, Garbanzol governs the synthesis of pro-inflammatory cytokines. Encouragingly, clinical trials demonstrate an encouraging safety profile, and an exceptional tolerance capacity. Group: Pharmaceutical. CAS No. 1226-22-8. Pack Sizes: 1 mg. Product ID: NP2448. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GGTI-298 | GGTI-298 is a selective geranylgeranyltransferase type I inhibitor that displays little effect on other prenylation enzymes such as farnesyltransferase. GGTI-298 causes G0-G1 cell cycle block and apoptosis in A549 cells (IC50 = 10 μM for A549 cells) and inhibits cell invasion and migration in COLO 320CM cells. Group: Pharmaceutical. CAS No. 180977-44-0. Pack Sizes: 5 mg. Product ID: B0084-272121. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GSK2193874 | GSK2193874 is a potent, orally active and specific antagonist of TRPV4 ion channels (IC50 values 2 and 40 nM for rat and human receptors, respectively). GSK2193874 is selective over a panel of ~200 human receptors, channels and enzymes. Group: Pharmaceutical. CAS No. 1336960-13-4. Pack Sizes: 20 mg. Product ID: B0084-007718. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GSK-LSD1 2HCl | GSK-LSD1 2HCl is an irreversible, and selective LSD1 inhibitor with IC50 of 16 nM, > 1000 fold selective over other closely related FAD utilizing enzymes (i.e. LSD2, MAO-A, MAO-B). Group: Pharmaceutical. CAS No. 1431368-48-7. Pack Sizes: 50 mg. Product ID: B2693-463426. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Guanosine 5'-diphosphate disodium salt | Guanosine 5'-diphosphate disodium salt is an imperative biomolecule esteemed in the biomedical sector, exhibiting noteworthy involvement in cellular signaling and serves as a substrate for diverse nucleic acid metabolism-encompassing enzymes. Its significance is exemplified through extensive employment in research and manufacturing, enabling comprehensive exploration of G-protein coupled receptors, protein synthesis and drug discovery-related signaling pathways, as well as disease research. Group: Pharmaceutical. CAS No. 7415-69-2. Pack Sizes: 10 g. Product ID: B2001-013437. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Hyaluronic acid disaccharide sodium salt | It is the only unsaturated disaccharide produced by hyaluronic acid in response to chondroitin enzymes ABC or AC-1. Group: Pharmaceutical. CAS No. 149368-06-9. Pack Sizes: 1 mg. Product ID: B2705-362868. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ilomastat | Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor, displaying potential anticancer activity. Ilomastat is a member of the hydroxamic acid class of reversible metallopeptidase inhibitors. The anionic state of the hydroxamic acid group forms a bidentate complex with the active site zinc. Ilomastat inhibits enzymes including thermolysin, peptide deformylase, and anthrax lethal factor endopeptidase (LF) produced by the bacterium Bacillus anthracis. Group: Pharmaceutical. CAS No. 142880-36-2. Pack Sizes: 25 mg. Product ID: B0084-302725. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ITI214 | ITI214 is a highly selective PDE1 inhibitor (Ki = 58 pM) at picomolar concentration without disrupting other PDE family members and a panel of enzymes, receptors, transporters, and ion channels. Group: Pharmaceutical. CAS No. 1642303-38-5. Pack Sizes: 100 mg. Product ID: B2693-474648. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaempferitrin | Kaempferitrin isolated from the root of Kaempferia galangal L. It stimulates glucose-metabolizing enzymes and promotes glucose homeostasis. Uses: Cytotoxic and antitumor effects; antidepressant-like effect; immunostimulatory effects. Group: Pharmaceutical. CAS No. 482-38-2. Pack Sizes: 20 mg. Product ID: NP1860. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Loxiglumide | Loxiglumide is an orally active, potent and selective small-molecule antagonist of the cholecystokinin receptor CCKA. It stimulates calorie intake and hunger feelings in humans. It could antagonize the CCK-induced reduction of gastric emptying in rats, accelerate the intestinal transport and accelerate the gallbladder emptying in mice. It inhibits pancreatic secretion of digestive enzymes, and also blocks CCK-induced gastric secretions and emptying. Uses: Loxiglumide stimulates calorie intake and hunger feelings in humans. it inhibits pancreatic secretion of digestive enzymes. Group: Pharmaceutical. CAS No. 107097-80-3. Pack Sizes: 50 mg. Product ID: B0084-053945. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| L-Sulforaphane | L-Sulforaphane is a compound with isothiocyanate group found in cruciferous vegetables such as broccoli, Brussels sprouts, and cabbages. It has been shown to regulate phase II detoxifying enzymes and induce cell cycle arrest or apoptosis in malignant cells in vitro and in vivo, thus can be potentially used as an antioxidant and anticancer agent. Uses: Anticarcinogenic agents. Group: Pharmaceutical. CAS No. 142825-10-3. Pack Sizes: 50 mg. Product ID: B2703-084008. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lycopene | Lycopene, in the concentration used, is not toxic and also its health benefits in adipose tissue may play a role against obesity-related complications. Lycopene in tomato puree has decreased indicating an indirect effect on lycopene stability caused by high concentration of hydrogen peroxide and the activation of peroxidase enzymes leading to the reduction of ascorbic acid and its regenerative action towards lycopene. Besides, Lycopene protected β-carotene against isomerization during reactions with singlet oxygen and radicals. These findings can explain the pattern of carotenoid isomers analyzed in fruits and vegetables, where lycopene containing samples showed higher (all-E)/(9Z)-β-carotene ratios, and also in in vivo samples such as human blood plasma. Lycopene can be used as pigment in food processing, and is also used as raw material of antioxidant health food. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 502-65-8. Pack Sizes: 1 g. Product ID: B0005-464994. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Methyl 4,6-O-benzylidene-a-D-glucopyranoside | Methyl 4,6-O-benzylidene-α-D-glucopyranoside, a fascinating compound, showcases immense potential in biomedical applications. Its remarkable inhibitory effects on α-glycosidase enzymes have garnered considerable attention in the pursuit of diabetes treatments. Moreover, this compound serves as a fundamental building block for the synthesis of groundbreaking carbohydrate-based therapeutic agents. Its employment paves the way for invaluable opportunities in drug discovery and design within the expansive realm of biomedicine. Group: Pharmaceutical. CAS No. 3162-96-7. Pack Sizes: 25 g. Product ID: B2705-294179. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Methyl b-D-glucuronide sodium salt | Methyl b-D-glucuronide sodium salt is a chemical compound used in the biomedical industry for its role in drug metabolism studies. It is commonly employed as a substrate to evaluate glucuronidation reactions mediated by glucuronosyltransferase enzymes. This product aids in understanding drug metabolism and its implications in treating various diseases by facilitating the study of drug elimination pathways. Group: Pharmaceutical. CAS No. 134253-42-2. Pack Sizes: 5 g. Product ID: B2705-209389. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Moxifloxacin-[d3] | Moxifloxacin-[d3] is a labelled form of Moxifloxacin. Moxifloxacin exerts its effects by trapping a DNA drug enzyme complex and specfically inhibiting ATP-dependent enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. Group: Pharmaceutical. CAS No. 1092356-42-7. Pack Sizes: 10 mg. Product ID: BLP-013398. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Moxifloxacin Hydrochloride | Moxifloxacin exerts its effects by trapping a DNA drug enzyme complex and specifically inhibiting ATP-dependent enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. It is a fluoroquinolone antibiotic with broad-spectrum bactericidal activity against gram-positive and gram-negative strains. Group: Pharmaceutical. CAS No. 186826-86-8. Pack Sizes: 100 g. Product ID: BBF-04614. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N2-iso-Butyroyl-3'-O-methylguanosine | N2-iso-Butyroyl-3'-O-methylguanosine - a valuable tool for biomedicine exploration. This organic compound finds frequent utility in mRNA synthesis, the development of capping analogs and high-affinity RNA aptamers. Its worth extends beyond these applications, with capabilities to examine structural and functional elements of mRNA capping enzymes. Group: Pharmaceutical. CAS No. 160107-07-3. Pack Sizes: 1 g. Product ID: B2706-346657. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Naringin | Naringin inhibits hepatic P-glycoprotein (P-gp) and some drug-metabolizing cytochrome P450 enzymes, including CYP3A4 and CYP1A2, which may result in drug-drug interactions. Naringin can be used as an edible additive, mainly for gum, refreshing drinks, etc. It is a plant polyphenol that can inhibit tyrosinase, block melanin synthesis, reduce skin pigment intensity, absorb UV, prevent photoaging, reduce sun damage and age spot formation, and whiten and lighten spots. It also has the anti-glycation and antibacterial effect, can effectively improve skin tone and skin texture, prevent the generation of age spots, remove red bloodlines, and improve skin blood microcirculation. Uses: Antioxidant, anticancer, anti-atherogenic. Group: Pharmaceutical. CAS No. 10236-47-2. Pack Sizes: 250 g. Product ID: NP1904. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Nitrocefin | Nitrocefin is a chromogenic cephalosporin substrate routinely used to detect the presence of beta-lactamase enzymes produced by various microbes. Group: Pharmaceutical. CAS No. 41906-86-9. Pack Sizes: 100 mg. Product ID: BBF-03759. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-(Quinoxalin-2-yl)-4-(quinoxalin-2-ylamino)benzenesulfonamide | N-(Quinoxalin-2-yl)-4-(quinoxalin-2-ylamino)benzenesulfonamide, an intriguing chemical substance, has garnered interest in the biomedical domain as a plausible remedy for assorted cancer types. This compound exerts its therapeutic effects by curbing certain enzymes and provoking apoptosis in malignant cells, thereby causing their demise. Although promising, further scientific investigations and clinical deliberations are fundamental to ascertain its potency and risk profiles. Group: Pharmaceutical. Pack Sizes: 1 mg. Product ID: B0001-254048. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-SMP | N-SMP is a potent synthetic compound known for its efficacy against various neurological disorders. As a powerful inhibitor, this compound specifically targets key enzymes involved in the progression of these debilitating diseases. In addition, N-SMP is also widely used as a linker for antibody-drug conjugation. Group: Pharmaceutical. CAS No. 55750-61-3. Pack Sizes: 5 g. Product ID: BAT-006479. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Trans-Feruloyltyramine | N-trans-Feruloyltyramine(NTF) ,a natural plant phenylpropanoid which is isolated from the herbs of Cannabis sativa L. exhibits the activity of anti-oxidative and has hepatoprotective effect. N-trans-Feruloyltyramine is likely to inhibit COX enzymes, thereby suppressing P-selectin expression on platelets, is a platelet aggregation inhibitor. Uses: Anti-oxidative. Group: Pharmaceutical. CAS No. 66648-43-9. Pack Sizes: 10 mg. Product ID: NP0183. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| OXi-4503 | OXi-4503 is the diphosphate prodrug of the stilbenoid combretastatin A1, originally isolated from the plant Combretum caffrum, with vascular-disrupting and antineoplastic activities. Upon administration, combretastatin A1 diphosphate (CA1P) is dephosphorylated to the active metabolite combretastatin A1 (CA1), which promotes rapid microtubule depolymerization; endothelial cell mitotic arrest and apoptosis, destruction of the tumor vasculature, disruption of tumor blood flow and tumor cell necrosis may ensue. In addition, orthoquinone intermediates, metabolized from combretastatin A1 by oxidative enzymes found to be elevated levels in some tumor types, may bind to tumor cell thiol-specific antioxidant proteins and DNA, and stimulate oxidative stress by enhancing superoxide/hydrogen peroxide production. CA1 binds to tubulin at the same site as colchicine but with higher affinity. Group: Pharmaceutical. CAS No. 288847-35-8. Pack Sizes: 100 mg. Product ID: B0084-353235. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Oxypeucedaninhydrate | Oxypeucedanin hydrate usually can be found in the roots of Angelica dahurica. It exhibited carbohydrate metabolizing enzymes inhibitory effect. Uses: Antimutagenic / antioxidant / antimicrobial. Group: Pharmaceutical. CAS No. 2643-85-8. Pack Sizes: 20 mg. Product ID: B2703-464765. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PF-1355 | PF-1355 is a selective, mechanism-based inhibitor of myeloperoxidase (MPO) (IC50 = 1.5 μM in LPS-stimulated human whole blood) with excellent selectivity for MPO without disrupting a panel of 50 receptors, enzymes, ion channels and transporters, including thyroid peroxidase. PF-1355 was used to test the hypothesis that MPO activity is a critical mediator of disease activity in immune complex vasculitis mouse models, and to support the confidence in rationale for this mechanism as a therapeutic approach to treat related human condition such as alleviating tissue injury caused by Goodpasture syndrome and pulmonary vasculitis induced by immune complexes. Group: Pharmaceutical. CAS No. 1435467-38-1. Pack Sizes: 50 mg. Product ID: B0084-474818. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Phenyl 4-O-acetyl-2,6-Di-O-benzoyl-1-thio-beta-thio-beta-D-galactopyranoside | Phenyl 4-O-acetyl-2,6-Di-O-benzoyl-1-thio-beta-thio-beta-D-galactopyranoside is a compound, exhibiting its paramount significance in delving deep into the enigmatic realms of glycosylation processes and the enthralling world of carbohydrate chemistry. It effortlessly assumes the dual roles of an eminent substrate in an immense array of biochemical assays, particularly those centered around the captivating realms of glycosyltransferases, glycosidases and various other riveting carbohydrate enzymes. Group: Pharmaceutical. CAS No. 152488-28-3. Pack Sizes: 1 g. Product ID: B1370-204821. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Phospho(enol)pyruvic acid tri(cyclohexylammonium) salt | The chemical compound, Phospho(enol)pyruvic acid tri(cyclohexylammonium) salt, is a complex and multifaceted substance extensively utilized in the biomedical field for investigating ailments related to glycolysis, such as cancer and diabetes. Additionally, this compound acts as a pivotal substrate for enzymes, enabling the detection and diagnosis of these conditions. Group: Pharmaceutical. CAS No. 35556-70-8. Pack Sizes: 1 g. Product ID: B2699-188833. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Pioglitazone hydrochloride | Pioglitazone hydrochloride, a thiazolidinedione antidiabetic drug, is a cytochrome P450 (CYP)2C8 and CYP3A4 enzymes inhibitor with Kis of 1.7, 11.8 and 32.1 μM for CYP2C8, CYP3A4 and CYP2C9, respectively. It is an agonist of the peroxisome proliferator-activated receptor &gamma. Uses: Hypoglycemic agents. Group: Pharmaceutical. CAS No. 112529-15-4. Pack Sizes: 250 mg. Product ID: BBF-05868. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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