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| Product | Description | |
|---|---|---|
| Emtricitabine | Emtricitabine moderately reduces hepatocyte proliferation independent of effects on mtDNA in HepG2 human hepatoma cells. Group: Pharmaceutical. Alternative Names: Emtricitabine; Coviracil; Emtriva; Racivir; (-)-FTC; W-201247; W-201248; E1007; 24229-EP2298783A1; 24229-EP2314590A1; AB01275429-01; 3B2-0188. CAS No. 143491-57-0. Pack Sizes: 10 g. Product ID: NP3265. Molecular formula: C8H10FN3O3S. Mole weight: 247.25. Custom synthesis is available. Send your inquiries for more information. |  London |
| Bictegravir | Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM for strand transfer activity. Bictegravir is a drug of the integrase inhibitor class that was copied from Dolutegravir by scientists at Gilead Sciences. Bictegravir also inhibits HIV-1 viral infection in MT-2 and MT-4 cells, CD4+ T cells, and macrophages (EC50s = 1.5, 2.5, 1.5, and 6.6 nM, respectively) without exhibiting cytotoxicity (CC50s = 10.3, 3.7, 13, and 29.8 μM, respectively). In 2016, bictegravir was in a Phase 3 trial as part of a single tablet regimen in combination with tenofovir alafenamide (TAF) and emtricitabine (FTC) for the treatment of HIV-1 infection. Group: Pharmaceutical. Alternative Names: GS-9883; GS 9883; GS9883. CAS No. 1611493-60-7. Pack Sizes: 100 mg. Product ID: B2693-058383. Molecular formula: C21H18F3N3O5. Mole weight: 449.39. Custom synthesis is available. Send your inquiries for more information. | London |
| (+)-Isomenthol | (+)-Isomenthol is an impurity of Emtricitabine, which is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Group: Pharmaceutical. Alternative Names: D-Isomenthol; (1S,2R,5R)-2-Isopropyl-5-methylcyclohexanol; (1S-(1alpha,2beta,5beta))-5-Methyl-(1-isopropyl)cyclohexan-2-ol; Emtricitabine Impurity 7; [1S-(1a,2b,5b)]-5-Methyl-2-(1-methylethyl)cyclohexanol; (1R,3S,4R)-(+)-Menthol; (1S,2R,5R)-(+)-Isomenthol. CAS No. 23283-97-8. Pack Sizes: 1 g. Product ID: B1370-310193. Molecular formula: C10H20O. Mole weight: 156.26. Custom synthesis is available. Send your inquiries for more information. | London |
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