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| Product | Description | |
|---|---|---|
| Doxorubicin | Doxorubicin. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 23214-92-8. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. Categories: adriamycin. |  Cenik Chemicals |
| Doxorubicin | Doxorubicin. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 23214-92-8. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. Categories: adriamycin. | Cenik Chemicals |
| Doxorubicin hydrochloride | 100mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Organics, Research Organics & Inorganics. Formula: C27H29NO11 ·HCl. CAS No. 25316-40-9. Prepack ID : 57489114-100mg. Molecular Weight : 579.98. |  |
| Doxorubicin hydrochloride | 25mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Organics, Research Organics & Inorganics. Formula: C27H29NO11 ·HCl. CAS No. 25316-40-9. Prepack ID : 57489114-25mg. Molecular Weight : 579.98. | |
| Doxorubicin hydrochloride | Doxorubicin is an anthracycline antibiotic with antineoplastic activity produced by the bacterium Streptomyces peucetius var. Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. Uses: Adcs cytotoxin. Group: Pharmaceutical. CAS No. 25316-40-9. Pack Sizes: 1 g. Product ID: BBF-03859. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Doxorubicin Impurities | Doxorubicin Impurities constitute an essential component within the biomedical sphere, pivotal for ascertaining the purity and therapeutic efficacy of the chemotherapeutic agent Doxorubicin. Utilized in numerous oncological treatments, including breast cancer, leukemia, and lymphoma, these impurities' identification and comprehension bolster drug safety and enhance therapeutic effectiveness. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 14-Bromodaunorubicin hydrochloride | 14-Bromodaunorubicin hydrochloride is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Group: Pharmaceutical. CAS No. 29742-67-4. Pack Sizes: 0.5 mg. Product ID: B0709-004062. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aclarubicin hydrochloride | Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting replication and repair of DNA and RNA, and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin. Uses: Antibiotics, antineoplastic. Group: Pharmaceutical. CAS No. 75443-99-1. Pack Sizes: 5 mg. Product ID: BBF-04081. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Anthraquinone Impurities | Anthraquinone Impurities, integral reference standards in biopharmaceutical pursuits, are essential in ensuring quality control of anthraquinone derivatives. They play a pivotal role in assessing drug stability, predominantly assisting in the synthesis of oncological treatments like doxorubicin and anti-inflammatory agents, thereby enhancing therapeutic efficacy and safety. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD3965 | AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, which is 6-fold selective over MCT2 and does not inhibit MCT4 at 10 μM. Both lactate transport and cell growth are potently inhibited by AZD3965 in lymphoma cell lines that preferentially express MCT1. Lactate transport inhibition in some cell lines also induces a cytotoxic effect. In vitro combination studies show that lactate transport inhibition can enhance the induction of cell death by doxorubicin. Blocking lactate transport in vitro also leads to a rapid inhibition of glucose uptake in the Raji Burkitt's lymphoma cell line. In vivo, AZD3965 is well tolerated and induces a dose- and time-dependent accumulation of lactate in the tumors, suppresses tumor growth and in the Raji model potentiates the effects of Rituxan, doxorubicin and bendamustine. The selective inhibition of lactate transport by the MCT1 inhibitor AZD3965 offers a novel mechanism for targeting the metabolic phenotype in tumors that preferentially express MCT1. Group: Pharmaceutical. CAS No. 1448671-31-5. Pack Sizes: 25 mg. Product ID: B2693-463251. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Daunorubicin EP Impurity B | Daunorubicinol, a metabolite of Daunorubicin, is an anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Group: Pharmaceutical. CAS No. 28008-55-1. Pack Sizes: 25 mg. Product ID: B0709-469824. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Dialdehyde starch | Dialdehyde starch is a biocompatible polymer used in biomedical field for drug delivery systems. With excellent stability and biodegradability, it enables controlled drug release, especially for anticancer compounds like doxorubicin and paclitaxel. Group: Pharmaceutical. CAS No. 9047-50-1. Pack Sizes: 100 mg. Product ID: B1370-330967. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Epirubicin Hydrochloride | Epirubicin HCl, a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. Uses: Antibiotics, antineoplastic. Group: Pharmaceutical. CAS No. 56390-09-1. Pack Sizes: 500 mg. Product ID: BBF-04657. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Nemorubicin | Nemorubicin, is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives. Uses: Adcs cytotoxin. Group: Pharmaceutical. CAS No. 108852-90-0. Pack Sizes: 10 mg. Product ID: BADC-00088. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| NU7441 | NU7441 is a highly potent and selective DNA-PK inhibitor (IC50=14 nM), exhibiting ATP-competitive inhibition kinetics. NU7441 increased the cytotoxicity of ionizing radiation and etoposide in SW620, LoVo, and V3-YAC cells but not in V3 cells, confirming that potentiation was due to DNA-PK inhibition. NU7441 substantially retarded the repair of ionizing radiation-induced and etoposide-induced DSB. NU7441 appreciably increased G(2)-M accumulation induced by ionizing radiation, etoposide, and doxorubicin in both SW620 and LoVo cells. In mice bearing SW620 xenografts, NU7441 concentrations in the tumor necessary for chemopotentiation in vitro were maintained for at least 4 hours at nontoxic doses. NU7441 increased etoposide-induced tumor growth delay 2-fold without exacerbating etoposide toxicity to unacceptable levels. In conclusion, NU7441 shows sufficient proof of principle through in vitro and in vivo chemosensitization and radiosensitization to justify further development of DNA-PK inhibitors for clinical use. Group: Pharmaceutical. CAS No. 503468-95-9. Pack Sizes: 100 mg. Product ID: B1370-194516. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PNU-159682 | PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes. It is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity, and shows >3,000-fold cytotoxic than its parent compound (MMDX and doxorubicin). It is a more potent and well tolerated ADC cytotoxin than doxorubicin. Uses: Adcs cytotoxin. Group: Pharmaceutical. CAS No. 202350-68-3. Pack Sizes: 5 mg. Product ID: BBF-05916. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Valrubicin | Valrubicin (AD-32) is a chemotherapy drug used to treat bladder cancer. It is a semisynthetic analog of the anthracycline doxorubicin, and is administered by infusion directly into the bladder. Uses: Antineoplastic. Group: Pharmaceutical. CAS No. 56124-62-0. Pack Sizes: 5 mg. Product ID: B0084-182305. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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