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| Product | Description | |
|---|---|---|
| Dovitinib | Dovitinib (TKI258) potently inhibited FLT3, c-KIT, FGFR, VEGFR1/2/3, PDGFRß and CSF-1R with IC50 values of 1, 2, 5, 10, 8, 27, 36 nM respectively. Dovitinib selectively blocked the growth of wild-type (WT) or activated mutant FGFR3-transformed B9 cells and human myeloma cell lines. Dovitinib was an effective treatment in a xenograft mouse model of FGFR3 multiple myeloma. Group: Pharmaceutical. Alternative Names: Dovitinib, TKI258; TKI 258;TKI-258; CHIR 265; CHIR265; CHIR-265; RAF-265; RAF 265; RAF265. CAS No. 405169-16-6. Pack Sizes: 50 mg. Product ID: B2693-091881. Molecular formula: C21H21FN6O. Mole weight: 392.429. Custom synthesis is available. Send your inquiries for more information. |  London |
| Ethyl 2-[5-(4-methylpiperazinyl)benzimidazol-2-yl]acetate | An impurity of Dovitinib, a potent VEGFR inhibitor exhibiting antitumor activity. Group: Pharmaceutical. Alternative Names: ethyl 2-(5-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)acetate. CAS No. 402948-37-2. Pack Sizes: 500 mg. Product ID: B2694-108985. Molecular formula: C16H22N4O2. Mole weight: 302.37. Custom synthesis is available. Send your inquiries for more information. | London |
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