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| Product | Description | |
|---|---|---|
| Dovitinib | Dovitinib (TKI258) potently inhibited FLT3, c-KIT, FGFR, VEGFR1/2/3, PDGFRß and CSF-1R with IC50 values of 1, 2, 5, 10, 8, 27, 36 nM respectively. Dovitinib selectively blocked the growth of wild-type (WT) or activated mutant FGFR3-transformed B9 cells and human myeloma cell lines. Dovitinib was an effective treatment in a xenograft mouse model of FGFR3 multiple myeloma. Group: Pharmaceutical. CAS No. 405169-16-6. Pack Sizes: 50 mg. Product ID: B2693-091881. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Dovitinib Impurities | Dovitinib Impurities, critical within the biomedical landscape, underpin the analytical evaluation and quality assurance processes for dovitiniba tyrosine kinase inhibitor integral to cancer therapies. These impurities provide crucial data on pharmacokinetics and safety metrics, advancing the strategic treatment of malignancies like renal cell carcinoma and breast cancer. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ethyl 2-[5-(4-methylpiperazinyl)benzimidazol-2-yl]acetate | An impurity of Dovitinib, a potent VEGFR inhibitor exhibiting antitumor activity. Group: Pharmaceutical. CAS No. 402948-37-2. Pack Sizes: 500 mg. Product ID: B2694-108985. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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