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5-Hydroxydopamine hydrochloride (CAS# 5720-26-3 ) is a useful research chemical. Group: Pharmaceutical. CAS No. 5720-26-3. Pack Sizes: 250 mg. Product ID: B2699-321447. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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N-acetyldopamine
N-acetyldopamine, an organic chemical compound, exhibits significant therapeutic potential in various neurodegenerative disorders, including Parkinson's disease, Attention Deficit Hyperactivity Disorder (ADHD), and depression. It has been extensively researched for its ability to act as an antioxidant and anti-inflammatory agent, enabling it to provide effective treatment against a host of oxidative stress disorders. Its clinical efficacy in treating these complex neurological conditions has made it a valuable compound in pharmaceutical research, with an ever-increasing scientific interest in unlocking its potential benefits. Group: Pharmaceutical. CAS No. 2494-12-4. Pack Sizes: 100 mg. Product ID: B0001-245589. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of safinamide, which is a selective monoamine oxidase B inhibitor reducing degradation of dopamine. Group: Pharmaceutical. CAS No. 174756-44-6. Pack Sizes: 1 mg. Product ID: B1605-458661. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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(2S,3S)-3-Hydroxypyrrolidine-2-carboxylic acid
(2S,3S)-3-Hydroxypyrrolidine-2-carboxylic acid, an essential substrate in the preparation of assorted biologically active molecules, is a formidable entity. This compound finds extensive utility as a chiral intermediate in the production of pharmacological agents with specific molecular arrangements. The synthetic derivatives of this intermediate exhibit GABA agonist and dopamine agonist activities with significant implications in managing pathologies related to Alzheimer's, Parkinson's and schizophrenia. Group: Pharmaceutical. CAS No. 4298-8-2. Pack Sizes: 100 mg. Product ID: B2699-117825. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An intermediate of Ropinirole. Ropinirole acts as a D2, D3, and D4 dopamine receptor agonist with highest affinity for D2. It is weakly active at the 5-HT2, and α2 receptors and is said to have virtually no affinity for the 5-HT1, GABA, mAChRs, α1, and β-adrenoreceptors. Group: Pharmaceutical. CAS No. 120427-95-4. Pack Sizes: 100 mg. Product ID: B2694-055636. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
An impurity of Brexpiprazole, a dopamine D2 partial agonist used as an atypical antipsychotic drug. Brexpiprazole has been approved for the treatment of schizophrenia. Group: Pharmaceutical. CAS No. 2059954-32-2. Pack Sizes: 100 mg. Product ID: B0461-284942. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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7-(4-Chlorobutoxy)quinolin-2(1H)-one
An impurity of Brexpiprazole, a dopamine D2 partial agonist used as an atypical antipsychotic drug. Brexpiprazole has been approved for the treatment of schizophrenia. Group: Pharmaceutical. CAS No. 913613-82-8. Pack Sizes: 100 mg. Product ID: B0461-116115. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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A 32390A
A 32390A is an antibiotic produced by Pyrenochaeta sp. (NRRL-5786). It has anti-gram-positive bacteria and fungi activity. It also inhibits the activity of dopamine tetra-hydroxylase, can reduce the level of norepinephrine in the heart and adrenal glands, and has a hypotensive effect on hypertensive rats. Group: Pharmaceutical. CAS No. 61241-59-6. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-03140. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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ABT 724 trihydrochloride
ABT 724 trihydrochloride is a potent dopamine D4 receptor partial agonist (EC50 = 12.4 nM; 61% efficacy vs. dopamine) for treatment of sexual dysfunction. Group: Pharmaceutical. CAS No. 587870-77-7. Pack Sizes: 100 mg. Product ID: B2693-375680. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Acein
Acein is a high-affinity angiotensin-converting enzyme (ACE) ligand with a Kd of 2.79 nM. It potentiates NMDA+ D-serine-induced dopamine release from the striatum in vivo and striatal slices in vitro. Group: Pharmaceutical. CAS No. 2022202-76-0. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016396. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Acein acetate
Acein acetate is a high-affinity angiotensin-converting enzyme (ACE) ligand with a Kd of 2.79 nM. It potentiates NMDA+ D-serine-induced dopamine release from the striatum in vivo and striatal slices in vitro. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016395. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Acepromazine-[d6]
Acepromazine-[d6] is an isotope compound of Acepromazine. Acetylpromazine is a phenothiazine derivative. It has depressant effect on the central nervous system and is used in the treatment of psychoses. It is now almost exclusively used on animals as a sedative and antiemetic. It is used primarily as a chemical restraint in hyperactive or fractious animals. It acts as a dopamine receptor antagonist in the central nervous system, thus causing sedation, muscular relaxation and a reduction in spontaneous activity. It acts as an antagonist on different postsysnaptic receptors - on dopaminergic receptors, on serotonergic receptors, on histaminergic receptors and so on. Group: Pharmaceutical. CAS No. 1173147-97-1. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003199. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Acetylcorynoline
Acetylcorynoline, which can be extracted from the tubers of Corydalis ambigua, inhibits the maturing of bone marrow-derived dendritic cells in mice. However, it is only cytotoxic in amounts of greater than 20 μM. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. Acetylcorynoline significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; prevents α-synuclein aggregation; recovers lipid content in OW13 strain; restores food-sensing behavior, and dopamine levels; and prolongs life-span in 6-hydroxydopamine-treated N2 strain, thus showing its potential as a possible antiparkinsonian drug. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes. Uses: Antifungal/anti-inflammatory. Group: Pharmaceutical. CAS No. 18797-80-3. Pack Sizes: 10 mg. Product ID: B2703-464490. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Adrogolide Impurities
Adrogolide Impurities are critical in pharmaceutical research, especially for assessing the purity and safety of dopaminergic drugs used in treating Parkinson's disease. These impurities help in understanding the pharmacokinetics and potential side effects of Adrogolide, thereby guiding the development of safer and more effective therapeutic agents. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Alizapride hydrochloride
Alizapride is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. Group: Pharmaceutical. CAS No. 59338-87-3. Pack Sizes: 200 mg. Product ID: B0084-095175. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Amisulpride Impurity B
An impurity of Amisulpride, a dopamine D2 receptor antagonist used for the treatment of acute and chronic schizophrenia. Group: Pharmaceutical. CAS No. 148516-54-5. Pack Sizes: 100 mg. Product ID: B2694-466488. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Amisulpride N-oxide
An impurity of Amisulpride, a dopamine D2 receptor antagonist used for the treatment of acute and chronic schizophrenia. Group: Pharmaceutical. CAS No. 71676-01-2. Pack Sizes: 25 mg. Product ID: B2694-466479. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Ansofaxine hydrochloride
Ansofaxine hydrochloride is a triple reuptake inhibitor of serotonin (IC50 = 723 nM), dopamine (IC50 = 491 nM) and norepinephrine (IC50 = 763 nM). Group: Pharmaceutical. CAS No. 916918-84-8. Pack Sizes: 100 mg. Product ID: B1370-007613. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Aripiprazole-[d8]
Aripiprazole-[d8] is the labelled analogue of Aripiprazole. Aripiprazole, a dihydroquinolinone derivative, is an antagonist of Dopamine-2 receptor and a partial agonist of 5-HT1A receptor. It could be used as an atypical antipsychotic agent. Uses: An isotopic labelled form of aripiprazole which is an antagonist of dopamine-2 receptor and a partial agonist of 5-ht1a receptor that could be used as an antipsychotic agent. Group: Pharmaceutical. CAS No. 1089115-06-9. Pack Sizes: 10 mg. Product ID: BLP-011791. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Aripiprazole lauroxil
Aripiprazole lauroxil is a Dopamine D2 receptor agonist, Serotonin 1A receptor agonist and ISerotonin 2A receptor antagonist under the development of Alkermes plc. Aripiprazole lauroxil is applicated as long-acting injectable atypical antipsychotic for the treatment of schizophrenia. It is an N-acyloxymethyl prodrug of aripiprazole. Uses: Schizophrenia. Group: Pharmaceutical. CAS No. 1259305-29-7. Pack Sizes: 100 mg. Product ID: B2693-475236. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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BL-918
BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1). It induces cytoprotective autophagy for Parkinson's disease treatment. It protected against MPTP-induced motor dysfunction and loss of dopaminergic neurons by targeting ULK1-modulated autophagy in mouse models of PD. Group: Pharmaceutical. CAS No. 2101517-69-3. Pack Sizes: 25 mg. Product ID: B2693-291256. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Brexpiprazole
Brexpiprazole is a novel atypical antipsychotic drug. It is a D2 dopamine partial agonist called serotonin-dopamine activity modulator (SDAM). It is a drug candidate useful in treatment and prevention of mental disorders including CNS disorders. Uses: Brexpiprazole is approved for the treatment of schizophrenia, and as an adjunctive treatment for depression. it is a drug candidate useful in treatment and prevention of mental disorders including cns disorders. Group: Pharmaceutical. CAS No. 913611-97-9. Pack Sizes: 1 g. Product ID: B0084-474906. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Bromocriptine Mesylate
Bromocriptine mesylate is the mesylate salt of Bromocriptine. It is a dopamine receptor agonist. It is a derivative of the ergotoxin group of ergot alkaloids. Uses: Antiparkinson agents. Group: Pharmaceutical. CAS No. 22260-51-1. Pack Sizes: 500 mg. Product ID: B2693-463773. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Cabergoline Impurity A
6-Allyl-8β-carboxyergoline is a metabolite of cabergoline which is a dopamine D2-receptor agonist. Group: Pharmaceutical. CAS No. 81409-74-7. Pack Sizes: 5 mg. Product ID: B0497-467954. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Cabergoline Impurity D
A metabolite of Cabergoline, having affinity for D1 and D2 dopamine receptors in rat striatum. Group: Pharmaceutical. CAS No. 85329-86-8. Pack Sizes: 5 mg. Product ID: B0497-467953. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Cariprazine hydrochloride
The hydrochloride salt form of Cariprazine, which is a highly selective inhibitor of Dopamine D3 and D2 receptor so that it might be effective as an antipsychotic agent. It has also been found to have moderate selectivity to serotonin 5-HT(1A) receptors. Uses: Antipsychotic agents. Group: Pharmaceutical. CAS No. 1083076-69-0. Pack Sizes: 50 mg. Product ID: B0084-474336. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Catalponol
Catalponol isolated from the roots of Ekmanianthe longiflora. It can enhance dopamine biosynthesis by inducing TH activity and protect against L-DOPA-induced cytotoxicity in PC12 cells. Group: Pharmaceutical. CAS No. 34168-56-4. Pack Sizes: 1 mg. Product ID: NP4300. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Dasotraline hydrochloride
Dasotraline hydrochloride, also called as SEP-225289 hydrochloride, is a metabolite of Sertraline and a novel inhibitor of dopamine and norepinephrine reuptake that blocks dopamine, norepinephrine, andserotonin transporters (IC50 = 4, 6, and 11 nM, respectively). Group: Pharmaceutical. CAS No. 675126-08-6. Pack Sizes: 5 mg. Product ID: B0084-241506. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Dexpramipexole
Dexpramipexole, also known as R-(+)-Pramipexole, is one of the impurities of pramipexole(USP D). It coule be used as a negative control in the research of dopamine receptors for the (S) form. It was also found to be a potential neuroprotective agent and p. Uses: Dexpramipexole, also known as r-(+)-pramipexole, is one of the impurities of pramipexole(usp d). Group: Pharmaceutical. CAS No. 104632-28-2. Pack Sizes: 50 mg. Product ID: B0084-241567. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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DL-Tetrahydroberberine
Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberberine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. Group: Pharmaceutical. CAS No. 522-97-4. Pack Sizes: 10 mg. Product ID: B2703-464701. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Docarpamine
Docarpamine is a prodrug of dopamine. Group: Pharmaceutical. CAS No. 74639-40-0. Pack Sizes: 250 mg. Product ID: B2692-132334. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Escitalopram
Escitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of escitalopram is found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Escitalopram does not inhibit monoamine oxidase. Uses: Serotonin uptake inhibitors; antidepressive agents, second-generation. Group: Pharmaceutical. CAS No. 128196-01-0. Pack Sizes: 500 mg. Product ID: B2693-461840. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Fluphenazine Decanoate Impurity 3
Fluphenazine Decanoate Impurity 3 is one of Fluphenazine impurities. Fluphenazine is a phenothiazine antipsychotic, a dopaminergic antagonist and an antiviral agent. Group: Pharmaceutical. CAS No. 76013-31-5. Pack Sizes: 5 mg. Product ID: B0963-151110. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Homovanillic Acid-[d3]
Homovanillic Acid-[d3] is an isotopically-labeled version of Homovanillic Acid (HVA). This important dopamine metabolite is predominantly found in human urine and is a valuable biochemical research tool for investigating the mechanisms underlying neuropsychiatric and neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, and schizophrenia. Its use in these studies is useful, given the marked alterations in dopamine metabolism and function that are observed in these conditions. Uses: A neuroendocrine tumor marker. a labelled metabolite of dihydroxyphenylacetic acid (dopac) by catechol o-methyltransferase. Group: Pharmaceutical. CAS No. 74495-71-9. Pack Sizes: 10 mg. Product ID: BLP-011889. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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L-Biopterin
L-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). It is an important cofactor in the production of many essential neurotransmitters, such as dopamine, seratonin and epinephrine, and plays an important role in the production of nitric oxide in the body. It has been shown to be cytotoxic to melanocytes in vitro, and may be a useful noninvasive biomarker. Group: Pharmaceutical. CAS No. 22150-76-1. Pack Sizes: 1 g. Product ID: B0084-467547. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Metoclopramide hydrochloride hydrate
Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist used to treat nausea and vomitin. Uses: A dopamine d2 antagonist. Group: Pharmaceutical. CAS No. 54143-57-6. Pack Sizes: 100 g. Product ID: B2692-071056. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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N 0924 hydrochloride
N 0924 hydrochloride is a dopamine (DA) receptor agonist that is the less active enantiomer of N-0437 in comparison with the opposite (S)-(-)-enantiomer, Rotigotine. Group: Pharmaceutical. CAS No. 125572-92-1. Pack Sizes: 50 mg. Product ID: B0084-056508. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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N-Despropyl Ropinirole HCl
An impurity of Ropinirole. Ropinirole acts as a D2, D3, and D4 dopamine receptor agonist with highest affinity for D2. It is weakly active at the 5-HT2, and α2 receptors and is said to have virtually no affinity for the 5-HT1, GABA, mAChRs, α1, and β-adrenoreceptors. Group: Pharmaceutical. CAS No. 173990-76-6. Pack Sizes: 10 mg. Product ID: B2694-479262. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Nepicastat HCl
Nepicastat hydrochloride (SYN117, RS-25560-197) is an inhibitor of dopamine beta-hydroxylase that catalyzes the conversion of dopamine to norepinephrine. Nepicastat hydrochloride shows the selective and concentration-dependent inhibition effects on bovine and human dopamine-beta-hydroxylase activity in vitro. In vivo, Nepicastat hydrochloride increases dopamine content and dopamine/noradrenaline ratio in a dose-dependent manner. Nepicastat hydrochloride also produces the similar effects on noradrenaline, dopamine and dopamine/noradrenaline ratio in tissues and plasma of beagle dogs. Nepicastat is currently in Phase II clinical trials in patients with Posttraumatic Stress Disorder. Uses: Nepicastat is currently in phase ii clinical trials in patients with posttraumatic stress disorder. Group: Pharmaceutical. CAS No. 170151-24-3. Pack Sizes: 50 mg. Product ID: B0084-453616. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Neurotensin (cattle)
Neurotensin, a gut tridecapeptide with many central and peripheral functions, acts as a potent cellular mitogen for various colorectal and pancreatic cancers which possess high-affinityneurotensin receptors(NTR). Neurotensin also can be used as neuromodulator of dopamine transmission and exerts potent hypothermic and analgesic effects. Group: Pharmaceutical. CAS No. 55508-42-4. Pack Sizes: 10 mg. Product ID: BAT-006175. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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N-Methyl-3,3-Diphenylpropylamine
N-Methyl-3,3-Diphenylpropylamine is an intriguing molecule that exhibits remarkable effects on the central nervous system, acting as a highly potent stimulant. Its usage in research has proven valuable in understanding the transport and regulatory mechanisms of dopamine and norepinephrine. Moreover, its therapeutic potential in addressing complex neurological disorders such as attention deficit hyperactivity disorder and narcolepsy bears considerable promise. Group: Pharmaceutical. CAS No. 28075-29-8. Pack Sizes: 10 g. Product ID: B2699-089274. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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N,N-Dimethyl-L-Tyrosine
N,N-Dimethyl-L-Tyrosine, a derivative of the amino acid tyrosine, has been a subject of interest in the research field due to its key role in elucidating amino acid metabolism. Additionally, it has been extensively studied for its precursor role in the synthesis of well-known neurotransmitters like dopamine and norepinephrine, thereby finding novel therapeutic applications in the treatment of neurodegenerative disorders such as Parkinson's disease and depression. The significance of this chemical compound could not be overstated in the realm of medicinal research. Group: Pharmaceutical. CAS No. 17350-74-2. Pack Sizes: 50 mg. Product ID: B2699-052153. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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n-Propyl Dioxepin
N-Propyl Dioxepin, a chemical compound, has been found to hold immense potential in the field of neuroscience due to its ability to be leveraged in the creation of new pharmaceuticals that are aimed at treating a range of neurological disorders, including but not limited to Alzheimer's disease and schizophrenia. This compound has been shown to be a wonderfully proficient antagonist of the dopamine receptors, as evidenced by preclinical studies. Group: Pharmaceutical. CAS No. 4469-34-5. Pack Sizes: 10 g. Product ID: B0001-118291. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Nuciferine
Nuciferine is a natural alkaloid compound isolated from the plants Nymphaea caerulea and Nelumbo nucifera. Nuciferine has a profile of action associated with dopamine receptor blockade. Group: Pharmaceutical. CAS No. 475-83-2. Pack Sizes: 500 mg. Product ID: NP0524. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Olanzapine Dimer Impurity
One of the impurities of Olanzapine. Olanzapine interacts with key receptors of interest in schizophrenia, having a nanomolar affinity for dopaminergic, serotonergic, alpha 1-adrenergic, and muscarinic receptors. Group: Pharmaceutical. Pack Sizes: 2 mg. Product ID: B2694-338783. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Olanzapine Impurity 25
One of the impurities of Olanzapine. Olanzapine interacts with key receptors of interest in schizophrenia, having a nanomolar affinity for dopaminergic, serotonergic, alpha 1-adrenergic, and muscarinic receptors. Group: Pharmaceutical. CAS No. 52833-34-8. Pack Sizes: 2 mg. Product ID: B2694-338782. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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ONC206
ONC206 is an imipiridone derivative that acts as an antagonist of dopamine D2-like receptors (DRD2/3/4). ONC206 inhibited cellular proliferation in a dose-dependent manner in serous endometrial cancer cell lines. Group: Pharmaceutical. CAS No. 1638178-87-6. Pack Sizes: 500 mg. Product ID: B1370-381380. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Ornipressin Acetate
Ornipressin is a vasoconstrictor, haemostatic and renal agent. Ornipressin plus dopamine can be a useful therapeutic option in patients with HRS type 1, especially as bridge to liver transplantation. Uses: Hemostatics. Group: Pharmaceutical. CAS No. 3397-23-7. Pack Sizes: 10 mg. Product ID: BAT-006198. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Paliperidone Palmitate
An impurity of Paliperidone which is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class of medications. Group: Pharmaceutical. CAS No. 199739-10-1. Pack Sizes: 1 g. Product ID: B2694-478526. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Paliperidone Palmitate N-Oxide
A metabolite of Paliperidone Palmitate, an impurity of Paliperidone which is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class of medications. Group: Pharmaceutical. CAS No. 1404053-60-6. Pack Sizes: 25 mg. Product ID: B2694-242591. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Palmatine hydrochloride
Palmatine hydrochloride (Palmatine chloride) is a hydrochloride salt of palmatine, a protoberberine alkaloid that has been used in the treatment of jaundice, dysentery, hypertension, inflammation, and liver-related diseases. It acts as an inhibitor of dopamine generation which reduces Ca2+ levels. Group: Pharmaceutical. CAS No. 10605-02-4. Pack Sizes: 10 g. Product ID: B2703-053775. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Pramipexole dihydrochloride monohydrate
Pramipexole is a dopamine agonist with Ki values of 3.9, 2.2, 0.5, 5.1 nM for D2S, D2L, D3 and D4 receptors respectively. It has been used for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS). Group: Pharmaceutical. CAS No. 191217-81-9. Pack Sizes: 5 g. Product ID: B0084-061932. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Pridopidine
Pridopidine, also known as ACR16, is a dopamine stabilizer used in the treatment of neurologic and psychiatric disorders. Uses: Dopamine d2 receptor antagonists; glutamate modulators; sigma-1 receptor agonists. Group: Pharmaceutical. CAS No. 346688-38-8. Pack Sizes: 100 mg. Product ID: B2693-110584. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Quinagolide Impurities
Quinagolide Impurities play a profound role in the biomedical field by aiding in analytical processes crucial for the development and quality control of quinagolide, a dopamine agonist. This analysis supports research and treatment of conditions like hyperprolactinemia, thereby enhancing therapeutic precision and efficacy in clinical applications. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Risperidal
Risperidone is a multi-targeted antagonist for dopamine, serotonin, adrenergic and histamine receptors, used to treat schizophrenia and bipolar disorder. Uses: Antipsychotic agents; dopamine antagonists; serotonin antagonists. Group: Pharmaceutical. CAS No. 106266-06-2. Pack Sizes: 20 mg. Product ID: NP3200. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Ropinirole Impurities
Ropinirole Impurities, integral to pharmaceutical scrutiny, play a vital role in the developmental landscape of ropinirole, a dopamine agonist indicated for Parkinson's and restless legs syndrome. Thorough analysis of these impurities underpins the safety, efficacy, and quality of formulations, aiding in adherence to stringent regulatory frameworks. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Rotigotine Hydrochloride
The hydrochloride salt form of Rotigotine which is a dopamine D2 and D3 receptor agonist and has been shown to be effective in the treatment of Parkinson's disease. IC50: 13 nM and 0.71 nM for D2 and D3 receptor respectively. Uses: The hydrochloride salt form of rotigotine which is a dopamine d2 and d3 receptor agonist and has been shown to be effective in the treatment of parkinson's disease. Group: Pharmaceutical. CAS No. 125572-93-2. Pack Sizes: 1 g. Product ID: B0046-082687. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Safinamide Impurity 5
An impurity of Safinamide, a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Group: Pharmaceutical. CAS No. 1160513-60-9. Pack Sizes: 25 mg. Product ID: B2694-479401. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Safinamide Impurity 8
An impurity of safinamide,safinamide is a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Group: Pharmaceutical. CAS No. 690969-16-5. Pack Sizes: 1 g. Product ID: B2694-479404. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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SB 277011A dihydrochloride
SB 277011A dihydrochloride is a selective and brain penetrating dopamine D3 receptor antagonist (pKi = 8.0, 6.0, 5.0 and <5.2 for D3, D2, 5-HT1D and 5-HT1B, respectively) with 100-fold selectivity over the hD2 receptor and over 66 other receptors. Group: Pharmaceutical. CAS No. 1226917-67-4. Pack Sizes: 50 mg. Product ID: B2693-320560. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Tetrabenazine
Tetrabenazine is a VMAT inhibitor used for the treatment of hyperkinetic movement disorder. It is a monoamine-depleting and dopamine-receptor-blocking drug, and is an effective and safe drug for the treatment of a variety of hyperkinetic movement disorders. Group: Pharmaceutical. CAS No. 58-46-8. Pack Sizes: 1 g. Product ID: B2693-451175. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Tetrahydropalmatine
Tetrahydropalmatine is isolated from the tubers of Corydalis yanhusuo W. T. Wang ex Z. Y. Su et C. Y. Wu. It depletes neurotransmitters, such as dopamine, noradrenaline and serotonin. Uses: Antibacterial. Group: Pharmaceutical. CAS No. 2934-97-6. Pack Sizes: 5 g. Product ID: B0084-474737. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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thiethylperazine
Thiethylperazine is a dopamine receptor antagonist It is an antiemetic of the phenothiazine class. Though it was never licensed or used as an antipsychotic, it may have such effects. It is useful in the treatment of nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. Uses: Antiemetic. Group: Pharmaceutical. CAS No. 1420-55-9. Pack Sizes: 50 mg. Product ID: B1370-058545. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Valbenazine
Valbenazine is a potent and highly selective vesicular monoamine transporter 2(VMAT2) inhibitor. It is a prodrug of the (+)-α isomer of tetrabenazine for tardive syndrome therapy. It is effective in regulating the levels of dopamine release during nerve communication, while at the same time having minimal impact on the other monoamines. It significantly improved tardive dyskinesia and was well tolerated in patients. It is an experimental drug being investigated for use in the treatment of tardive dyskinesia and Tourette syndrome. It was developed by Neurocrine Biosciences. Uses: Valbenazine is an experimental drug being investigated for use in the treatment of tardive dyskinesia and tourette syndrome. Group: Pharmaceutical. CAS No. 1025504-45-3. Pack Sizes: 10 mg. Product ID: B0084-474971. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Venlafaxine
Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It is licensed for the treatment of major depressive disorder (MDD), as the treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. It can increase dopamine neurotransmission in this part of the brain. It has seemingly superior efficacy in severe depression as a narcotic and is increasingly used as a measure of last resort for refractory cases. Group: Pharmaceutical. CAS No. 93413-69-5. Pack Sizes: 500 mg. Product ID: NP3405. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Venlafaxine hydrochloride
Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It is licensed for the treatment of major depressive disorder (MDD), as a treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. It can increase dopamine neurotransmission in this part of the brain. It is seemingly superior efficacy in severe depression as narcotics become increasingly used as a measure of last resort for refractory cases. Uses: Antidepressant. Group: Pharmaceutical. CAS No. 99300-78-4. Pack Sizes: 10 g. Product ID: NP3427. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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WAY-100635 maleate
WAY-100635 maleate is a potent and selective 5-hydroxytryptamine1A antagonist for 5-HT ( IC50= 0.95 ± 0.12 nM ), and also exhibits agonist activity at dopamine D4 receptors. Uses: Potent, silent antagonist of 5-ht1a receptors. Group: Pharmaceutical. CAS No. 634908-75-1. Pack Sizes: 50 mg. Product ID: B0084-305101. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Zuclopenthixol acetate
Zuclopenthixol is a typical antipsychotic drug that belongs to thioxanthene class. Zuclopenthixol is the cis-isomer of clopenthixol. Zuclopenthixol has not been approved for use in the United States. It is a dopamine D1/D2 receptor antagonist used for the treatment of Schizophrenia. Uses: Schizophrenia. Group: Pharmaceutical. CAS No. 85721-05-7. Pack Sizes: 1 g. Product ID: B1370-152978. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Zuclopenthixol Decanoate
Zuclopenthixol decanoate is a typical antipsychotic drug belonging to the thioxanthene class. lt has high affinity for both dopamine D1 and D2 receptors, for α1-adrenoceptors and 5-HT2 receptors but has no affinity for cholinergic muscarine receptors. It is used in the maintenance treatment of chronic schizophrenic patients. lt is not approved for use in the United States. It was introduced in 1962 by Lundbeck. Uses: Zuclopenthixol decanoate is used in the maintenance treatment of chronic schizophrenic patients. Group: Pharmaceutical. CAS No. 64053-00-5. Pack Sizes: 1 g. Product ID: B1370-419146. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Zuclopenthixol dihydrochloride
Zuclopenthixol dihydrochloride is an antagonist at D1 and D2 dopamine receptors. Zuclopenthixol also has high affinity for alpha1-adrenergic and 5-HT2 receptors, but it has weaker histamine H1 receptor blocking activity, and even lower affinity for muscarinic cholinergic and alpha2-adrenergic receptors. lt is the cis-isomer of clopenthixol. It is an antipsychotic drug belonging the thioxanthene class. Group: Pharmaceutical. CAS No. 58045-23-1. Pack Sizes: 100 mg. Product ID: B1370-285267. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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