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| Product | Description | |
|---|---|---|
| Dolastatin 10 | Dolastatin 10 is a potent antimitotic peptide from a marine animal, strongly inhibiting microtubule assembly. Uses: Adcs cytotoxin. Group: Pharmaceutical. Alternative Names: DLS 10; NSC 376128; Dolastatin-10; DLS-10; DLS10; NSC376128; NSC-376128; L-Valinamide, N,N-dimethyl-L-valyl-N-[2-methoxy-4-[2-[1-methoxy-2-methyl-3-oxo-3-[[2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-(1-methylpropyl)-4-oxobutyl]-N-methyl-,[2S-[1[1R*(R*),2S*],2R*[1S*,2S*,3(R*)]]]-. CAS No. 110417-88-4. Pack Sizes: 5 mg. Product ID: BAT-010469. Molecular formula: C42H68N6O6S. Mole weight: 785.09. Custom synthesis is available. Send your inquiries for more information. |  London |
| Auristatin E | Auristatin E is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization. Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity. Uses: Adcs cytotoxin. Group: Pharmaceutical. Alternative Names: Auristatin E. CAS No. 160800-57-7. Pack Sizes: 5 mg. Product ID: BADC-00188. Molecular formula: C40H69N5O7. Mole weight: 732.01. Custom synthesis is available. Send your inquiries for more information. | London |
| Auristatin F | Auristatin F, a synthetic analog of dolastatin 10, is a cytotoxic tubulin modifier with potent and selective antitumor activity. It is an MMAF analog and cytotoxin in Antibody-drug conjugates. Uses: Adcs cytotoxin. Group: Pharmaceutical. Alternative Names: N,N-Dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. CAS No. 163768-50-1. Pack Sizes: 25 mg. Product ID: BBF-05829. Molecular formula: C40H67N5O8. Mole weight: 745.99. Custom synthesis is available. Send your inquiries for more information. | London |
| MMAD | Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate. Uses: Adcs cytotoxin. Group: Pharmaceutical. Alternative Names: Demethyldolastatin 10; Monomethylauristatin D; Monomethyl Dolastatin 10. CAS No. 203849-91-6. Pack Sizes: 10 mg. Product ID: BADC-00309. Molecular formula: C41H66N6O6S. Mole weight: 771.06. Custom synthesis is available. Send your inquiries for more information. | London |
| MMAE | Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is commonly conjugated with monoclonal antibodies directed at antigens specific to cancer cells for tumor-directed cytotoxicity. Uses: Adcs cytotoxin. Group: Pharmaceutical. Alternative Names: MMAE; Vedotin; Monomethyl auristatin E; Monomethylauristatin E; N-methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino}-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl}-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide. CAS No. 474645-27-7. Pack Sizes: 25 mg. Product ID: BBF-05782. Molecular formula: C39H67N5O7. Mole weight: 717.98. Custom synthesis is available. Send your inquiries for more information. | London |
| Vat-Cit-PAB-MMAD | Vat-Cit-PAB-MMAD is a protective group conjugated MMAD, MMAD is a toxin payload in antibody drug conjugate. Group: Pharmaceutical. Alternative Names: Vat-Cit-PAB-Monomethyl Dolastatin 10. CAS No. 1415329-13-3. Pack Sizes: 5 mg. Product ID: BADC-00016. Molecular formula: C60H93N11O11S. Mole weight: 1176.51. Custom synthesis is available. Send your inquiries for more information. | London |
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