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Dichlorophenyl borane. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 873-51-8. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications.
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2-Amino-2-(2,4-dichlorophenyl)ethanol
2-Amino-2-(2,4-dichlorophenyl)ethanol. Group: Pharmaceutical. Alternative Names: 2-amino-2-(2,4-dichlorophenyl)ethan-1-ol. CAS No. 1184839-78-8. Pack Sizes: 100 mg. Product ID: BB077428. Molecular formula: C8H9Cl2NO. Mole weight: 206.07. Custom synthesis is available. Send your inquiries for more information.
London
3,4-Dichlorophenylguanidinium nitrate
3,4-Dichlorophenylguanidinium nitrate, a chemical compound employed in biomedical research as a pharmacological instrument to investigate the mechanisms of action of assorted medications targeting specific receptors in the human body, denoted by its potentiality as a drug candidate for the treatment of ailments like hypertension, glaucoma, and other cardiovascular disorders. Group: Pharmaceutical. CAS No. 65783-11-1. Pack Sizes: 100 g. Product ID: B2699-257187. Molecular formula: C7H8Cl2N4O3. Mole weight: 267.07. Custom synthesis is available. Send your inquiries for more information.
4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride is a remarkable pharmaceutical compound functioning as a selectively potent serotonin reuptake inhibitor (SSRI). It has garnered medical interest for its significant contributions to the research of depression and anxiety disorders. Group: Pharmaceutical. CAS No. 79617-89-3. Pack Sizes: 100 mg. Product ID: B1331-401092. Custom synthesis is available. Send your inquiries for more information.
5-[(2,4-Dichlorophenyl)methylidene]-1,3-thiazolidine-2,4-dione is a potential PPAR agonist with antibacterial, antidiabetic and antioxidant activities. The esteemed 5-[(2,4-Dichlorophenyl)methylidene]-1,3-thiazolidine-2,4-dione is a highly efficacious agent utilized in the management of type 2 diabetes mellitus. By enhancing insulin secretion and suppressing hepatic glucose output, it diligently lowers blood glucose concentrations, thereby promoting normoglycemia. Its demonstrated efficacy and mechanism of action render it an alluring therapeutic option for those with the aforementioned condition. Group: Pharmaceutical. Alternative Names: NSC 31150; Antimicrobial agent-33. CAS No. 51244-45-2. Pack Sizes: 50 mg. Product ID: B0001-284765. Molecular formula: C10H5Cl2NO2S. Mole weight: 274.115. Custom synthesis is available. Send your inquiries for more information.
Hydrazine Carboximidamide 2-[cyano(2,3-Dichlorophenyl)]methane Uses: Pharmaceutical Research and Development. Group: Intermediates. CAS No. 84689-20-3. Pack Sizes: Enquire for MOQ. Categories: NORDMANN UK Fine Chemicals: innovative sourcing and supply.
UK / EU / USA / Japan
(R)-2-Chloro-1-(2,4-Dichlorophenyl)Ethanol
(R)-2-Chloro-1-(2,4-Dichlorophenyl)Ethanol Uses: Pharmaceutical Research and Development. Group: Chiral Building Blocks. Grades: ee:99.9%+. CAS No. 13629-14-3. Pack Sizes: Enquire for MOQ. Categories: Nordmann UK Fine Chemicals (Formerly Melrob-Eurolabs).
UK / EU / USA / Japan
(S)-2-Chloro-1-(2,4-Dichlorophenyl)Ethanol
(S)-2-Chloro-1-(2,4-Dichlorophenyl)Ethanol Uses: Pharmaceutical Research and Development. Group: Chiral Building Blocks. Grades: ee:99.9%+. CAS No. 126534-31-4. Pack Sizes: Enquire for MOQ. Categories: NORDMANN innovative sourcing and supply.
(S)-2-Chloro-1-(2,4-dichlorophenyl)ethyl methanesulfonate Uses: Pharmaceutical R&D. Group: Chiral Building Blocks. Grades: ee:99.9%+. CAS No. 229334-55-8. Pack Sizes: Enquire for MOQ. Categories: NORDMANN Key intermediates and specialty chemicals suppliers.
UK / EU / USA / Japan
4'-Amino-3',5'-dichloroacetophenone
4'-Amino-3',5'-dichloroacetophenone (CAS# 37148-48-4) is a compound useful in organic synthesis. Group: Pharmaceutical. Alternative Names: 1-(4-amino-3,5-dichlorophenyl)ethanone; 1-(4-amino-3,5-dichlorophenyl)ethanone. CAS No. 37148-48-4. Pack Sizes: 1mg;1g;10g. Product ID: NP2958. Molecular formula: C8H7Cl2NO. Mole weight: 204.05. Custom synthesis is available. Send your inquiries for more information.
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A 438079 hydrochloride
A 438079 hydrochloride is a competitive P2X7 receptor antagonist with pIC50 value of 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line. It protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, but not by inflammasome activation. It partially but significantly prevented the 6-OHDA-induced depletion of striatal DA stores. Group: Pharmaceutical. Alternative Names: 3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride;A-438079 HCl;A-438079 hydrochloride; A438079 hydrochloride; A 438079 hydrochloride. CAS No. 899507-36-9. Pack Sizes: 1mg;1g;10g. Product ID: 899507-36-9. Molecular formula: C13H10Cl3N5. Mole weight: 342.61. Custom synthesis is available. Send your inquiries for more information.
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A 839977
A-839977 is a novel and selective P2X7 antagonist. It blocks BzATP-evoked calcium influx at recombinant human, rat and mouse P2X7 receptors with IC50 values 20, 42 and 150 nM respectively. It also potently blocked agonist-evoked YO-PRO uptake and IL-1beta release from differentiated human THP-1 cells. It also produced robust antihyperalgesia in the CFA model of inflammatory pain in wild-type mice. It has been exhibited to reduce CFA-induced thermal hyperalgesia in a dose-dependent fashion with the ED50 value of 100μmol/kg. Group: Pharmaceutical. Alternative Names: 1-(2,3-Dichlorophenyl)-N-[[2-[(pyridin-2-yl)oxy]phenyl]methyl]-1H-tetrazol-5-amine. CAS No. 870061-27-1. Pack Sizes: 1mg;1g;10g. Product ID: 870061-27-1. Molecular formula: C19H14Cl2N6O. Mole weight: 413.26. Custom synthesis is available. Send your inquiries for more information.
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A-893
A-893 is an inhibitor of SMYD2, which is a lysine methyltransferase. The co-crystal structure reveals the origin of enhanced potency, and effective inhibition of p53K370 methylation in a lung carcinoma (A549) cell line. Group: Pharmaceutical. Alternative Names: A893; A 893; (R)-N-cyclohexyl-3-((3,4-dichlorophenethyl)amino)-N-(2-((2-hydroxy-2-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)ethyl)amino)ethyl)propanamide; Propanamide, N-cyclohexyl-3-[[2-(3,4-dichlorophenyl)ethyl]amino]-N-[2-[[(2R)-2-(3,4-dihydro-3-oxo-2H-1,4-benzoxazin-8-yl)-2-hydroxyethyl]amino]ethyl]-; N-Cyclohexyl-N3-[2-(3,4-dichlorophenyl)ethyl]-N-(2-{[(2R)-2-hydroxy-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-8-yl)ethyl]amino}ethyl)-β-alaninamide. CAS No. 1868232-32-9. Pack Sizes: 1mg;1g;10g. Product ID: 1868232-32-9. Molecular formula: C29H38Cl2N4O4. Mole weight: 577.54. Custom synthesis is available. Send your inquiries for more information.
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ABD459
ABD459 is a neutral antagonist of the central cannabinoid 1 (CB1) receptor (Ki = 8.6 nM). Group: Pharmaceutical. Alternative Names: [5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl](4-methoxyphenyl)-methanone. CAS No. 1047670-51-8. Pack Sizes: 1mg;1g;10g. Product ID: 1047670-51-8. Molecular formula: C24H17BrCl2N2O2. Mole weight: 516.2. Custom synthesis is available. Send your inquiries for more information.
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AC 41848
AC 41848 is a potent, cell permeable, and subtype selective retinoic acid receptor RARγ agonist with an EC50 of 5.9 μM. Group: Pharmaceutical. Alternative Names: 1-[(2,4-Dichlorophenyl)methyl]-6,7,8,9-tetrahydro-3-phenyl-5H-imidazo[1,2-a]azepinium Bromide; 1-(2,4-Dichlorobenzyl)-3-phenyl-1,5,6,7,8,9-hexahydroimidazo[1,2-a]azepin-4-ium bromide; 5H-Imidazo[1,2-a]azepinium, 1-[(2,4-dichlorophenyl)methyl]-6,7,8,9-tetrahydro-3-phenyl-, bromide (1:1). CAS No. 400856-69-1. Pack Sizes: 1mg;1g;10g. Product ID: 400856-69-1. Molecular formula: C21H21BrCl2N2. Mole weight: 452.21. Custom synthesis is available. Send your inquiries for more information. Categories: AC41848.
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AGK2
AGK2 is a potent, and selective SIRT2 inhibitor with IC50 of 3.5 μM. Group: Pharmaceutical. Alternative Names: AGK-2; AGK 2; 2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(quinolin-5-yl)acrylamide. CAS No. 304896-28-4. Pack Sizes: 100 mg. Product ID: B1370-271992. Molecular formula: C23H13Cl2N3O2. Mole weight: 434.27. Custom synthesis is available. Send your inquiries for more information.
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Anagrelide USP Related Compound A
An impurity of Anagrelide, a medication used to treat essential thrombocytosis or overproduction of blood platelets. Group: Pharmaceutical. Alternative Names: Ethyl 2-(6-amino-2,3-dichlorobenzylamino)acetate; Anagrelide hydrochloride USP Related Compound A; Glycine, N-[(6-amino-2,3-dichlorophenyl)methyl]-, ethyl ester; Anagrelide Related Compound A; N-[(6-Amino-2,3-dichlorophenyl)methyl]glycine ethyl ester; USP Anagrelide Related Impurity A; Ethyl N-(2,3-dichloro-6-aminobenzyl)glcycine; Ethyl (2-amino-5,6-dichlorobenzyl)aminoacetate; Ethyl N-(6-amino-2,3-dichlorobenzyl)glycine; N-(6-Amino-2,3-dichlorobenzyl)glycine ethyl ester. CAS No. 70406-92-7. Pack Sizes: 1 g. Product ID: B2699-075619. Molecular formula: C11H14Cl2N2O2. Mole weight: 277.15. Custom synthesis is available. Send your inquiries for more information.
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Aripiprazole-[d8]
Aripiprazole-[d8] is the labelled analogue of Aripiprazole. Aripiprazole, a dihydroquinolinone derivative, is an antagonist of Dopamine-2 receptor and a partial agonist of 5-HT1A receptor. It could be used as an atypical antipsychotic agent. Uses: An isotopic labelled form of aripiprazole which is an antagonist of dopamine-2 receptor and a partial agonist of 5-ht1a receptor that could be used as an antipsychotic agent. Group: Pharmaceutical. Alternative Names: Aripiprazole D8; 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydro-2(1H)-quinolinone; 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydrocarbostyril; Abilify-d8; Abilitat-d8; Aripiprazole-d8; OPC 14597-d8; 2(1H)?-Quinolinone, 7-[4-[4-(2,?3-dichlorophenyl)?-1-piperazinyl-2,?2,?3,?3,?5,?5,?6,?6-d8]?butoxy]?-3,?4-dihydro-. CAS No. 1089115-06-9. Pack Sizes: 10 mg. Product ID: BLP-011791. Molecular formula: C23H19D8Cl2N3O2. Mole weight: 456.43. Custom synthesis is available. Send your inquiries for more information.
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Aripiprazole Impurity 4
A metabolite of Aripiprazole. Group: Pharmaceutical. Alternative Names: 1-[4-[(1,2,3,4-Tetrahydro-2-oxo-7-quinolinyl)oxy]butyl] Aripiprazole; 7-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)-1-(4-((2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy)butyl)-3,4-dihydroquinolin-2(1H)-one. CAS No. 1424857-63-5. Pack Sizes: 10 mg. Product ID: B0090-466789. Molecular formula: C36H42Cl2N4O4. Mole weight: 665.67. Custom synthesis is available. Send your inquiries for more information.
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Aripiprazole lauroxil
Aripiprazole lauroxil is a Dopamine D2 receptor agonist, Serotonin 1A receptor agonist and ISerotonin 2A receptor antagonist under the development of Alkermes plc. Aripiprazole lauroxil is applicated as long-acting injectable atypical antipsychotic for the treatment of schizophrenia. It is an N-acyloxymethyl prodrug of aripiprazole. Uses: Schizophrenia. Group: Pharmaceutical. Alternative Names: Aristada; RDC-3317; RDC 3317; RDC3317; UNII-B786J7A343; ALKS 9070; ALKS9070; ALKS-9070; ALKS 9072; ALKS-9072; ALKS9072; [7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-2-oxo-3,4-dihydroquinolin-1-yl]methyl dodecanoate. CAS No. 1259305-29-7. Pack Sizes: 100 mg. Product ID: B2693-475236. Molecular formula: C36H51Cl2N3O4. Mole weight: 660.72. Custom synthesis is available. Send your inquiries for more information.
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BD 1047 dihydrobromide
The dihydrobromide salt form of BD-1047, a selective σ1 receptor antagonist, has been found to have antipsychotic effect and could be probably used against schizophrenia and neuropathic pain. Uses: Bd 1047 dihydrobromide is a selective antagonist of σ receptors. Group: Pharmaceutical. Alternative Names: BD-1047 (dihydrobromide); BD-1047 dihydrobromide; N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine dihydrobromide. CAS No. 138356-21-5. Pack Sizes: 1 g. Product ID: B1370-361794. Molecular formula: C13H22Br2Cl2N2. Mole weight: 437.04. Custom synthesis is available. Send your inquiries for more information.
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Bifenox-[d3]
Bifenox-[d3] is a labelled compound of Bifenox which is a herbicide. Group: Pharmaceutical. Alternative Names: Bifenox-d3 (2,4-dichlorophenoxy-d3); 5-(2,4-Dichlorophenoxy)-2-nitrobenzoic Acid Methyl Ester-d3; 2,4-Dichlorophenyl 3-(Methoxycarbonyl)-4-nitrophenyl Ether-d3; Methyl 5-(2,4-Dichlorophenoxy)-2-nitrobenzoate. Pack Sizes: 10 mg. Product ID: BLP-003459. Molecular formula: C14H6D3Cl2NO5. Mole weight: 345.15. Custom synthesis is available. Send your inquiries for more information.
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BIO 5192
BIO 5192 is a selective and potent inhibitor of integrin α4β1 (Very Late Antigen-4; VLA-4) (Kd < 10 pM) with selectivity for α4β1 over a range of other integrins (IC50 values are 1.8, 138, 1053,> 500 and > 10,000 nM for α4β1, α9β1, α2β1, α4β7 and αIIbβ3, respectively). BIO 5192 causes a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels. Group: Pharmaceutical. Alternative Names: BIO-5192; AMD-15057; BIO 5192; AMD 15057; BIO5192; AMD15057; (2S)-2-[[[(2S)-1-[(3,5-Dichlorophenyl)sulfonyl]-2-pyrrolidinyl]carbonyl]amino]-4-[[(2S)-4-methyl-2-[methyl[2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl]amino]-1-oxopentyl]amino]butanoic acid. CAS No. 327613-57-0. Pack Sizes: 10 mg. Product ID: B2693-119144. Molecular formula: C38H46Cl2N6O8S. Mole weight: 817.78. Custom synthesis is available. Send your inquiries for more information.
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Brilaroxazine
Brilaroxazine acts as an antipsychotic which may be effective in the treatment of schizophrenia and bipolar disorder. It is a potent and orally active multimodal dopamine (DA)/serotonin (5-HT) modulator. Group: Pharmaceutical. Alternative Names: 2H-1,4-Benzoxazin-3(4H)-one, 6-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butoxy)-; RP-5063. CAS No. 1239729-06-6. Pack Sizes: 5 mg. Product ID: B1370-339573. Molecular formula: C22H25Cl2N3O3. Mole weight: 450.36. Custom synthesis is available. Send your inquiries for more information.
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Cariprazine hydrochloride
The hydrochloride salt form of Cariprazine, which is a highly selective inhibitor of Dopamine D3 and D2 receptor so that it might be effective as an antipsychotic agent. It has also been found to have moderate selectivity to serotonin 5-HT(1A) receptors. Uses: Antipsychotic agents. Group: Pharmaceutical. Alternative Names: Cariprazine HCl; Vraylar; 3-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]-1,1-dimethylurea hydrochloride. CAS No. 1083076-69-0. Pack Sizes: 50 mg. Product ID: B0084-474336. Molecular formula: C21H33Cl3N4O. Mole weight: 463.87. Custom synthesis is available. Send your inquiries for more information.
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Cariprazine-[piperazine-d8]
Cariprazine-[piperazine-d8] is a labelled Cariprazine. Cariprazine is an atypical antipsychotic used for the treatment of schizophrenia and bipolar mania. Group: Pharmaceutical. Alternative Names: Cariprazine-d8; 3-((1r,4r)-4-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl-2,2,3,3,5,5,6,6-d8)ethyl)cyclohexyl)-1,1-dimethylurea; 3,3-dimethyl-1-[(1r,4r)-4-{2-[4-(2,3-dichlorophenyl)(D8)piperazin-1-yl]ethyl}cyclohexyl]urea; N'-[trans-4-[2-[4-(2,3-Dichlorophenyl)-1-piperazinyl-2,2,3,3,5,5,6,6-d8]ethyl]cyclohexyl]-N,N-dimethylurea; Cariprazine D8. CAS No. 1308278-50-3. Pack Sizes: 20 mg. Product ID: BLP-013098. Molecular formula: C21H24D8Cl2N4O. Mole weight: 435.46. Custom synthesis is available. Send your inquiries for more information.
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CGP 52432
CGP52432 is a potent and selective GABAB receptor antagonist with IC50 value of 85 nM. Group: Pharmaceutical. Alternative Names: Cgp 52432; Cgp52432; Cgp52432; 3-[[(3,4-Dichlorophenyl)methyl]amino]propyl] diethoxymethyl)phosphinic acid. CAS No. 139667-74-6. Pack Sizes: 20 mg. Product ID: B0084-211080. Molecular formula: C15H24Cl2NO4P. Mole weight: 384.24. Custom synthesis is available. Send your inquiries for more information.
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CHIR-99021
CHIR-99021 (CT99021) is a glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo. It enhances reprogramming of mouse embryonic fibroblasts, transduced by Oct4 and Klf4 only, into iPSCs in combination with tranylcypromine. It also induces cardiomyocyte differentiation from human embryonic stem (ES). Uses: Potential antineoplastic agent. Group: Pharmaceutical. Alternative Names: CHIR-99021; CT99021; 6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile. CAS No. 252917-06-9. Pack Sizes: 100 mg. Product ID: B0084-462893. Molecular formula: C22H18Cl2N8. Mole weight: 465.342. Custom synthesis is available. Send your inquiries for more information.
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Cilofexor
Cilofexor is a farnesoid X receptor (FXR) agonist. Cilofexor inhibits binding of a synthetic peptide, comprising residues 676-700 of the steroid receptor coactivator 1 (SRC-1), to the farnesoid X receptor (FXR; EC50 = <25 nM in a FRET activity assay). Group: Pharmaceutical. Alternative Names: 2-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid. CAS No. 1418274-28-8. Pack Sizes: 25 mg. Product ID: B2693-291596. Molecular formula: C28H22Cl3N3O5. Mole weight: 586.9. Custom synthesis is available. Send your inquiries for more information.
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Clenbuterol Impurity E
Clenbuterol Impurity E is an impurity of Clenbuterol and is used as a reagent in the synthesis of pyrazolopyridine derivatives as inhibitors of phosphodiesterase-4 (PDE-IV) and production of tumor necrosis factor-α (TNF-α). Group: Pharmaceutical. Alternative Names: 4-Amino-3,5-dichlorophenacylbromide; 1-(4-Amino-3,5-dichlorophenyl)-2-bromoethan-1-one. CAS No. 37148-47-3. Pack Sizes: 1 g. Product ID: B2694-469119. Molecular formula: C8H6BrCl2NO. Mole weight: 282.95. Custom synthesis is available. Send your inquiries for more information.
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Clevidipine butyrate
Clevidipine Butyrate is a dihydropyridine calcium channel blocker, uses as an agent for the reduction of blood pressure. Group: Pharmaceutical. Alternative Names: 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid 3-Methyl 5-[(1-Oxobutoxy)methyl] Ester; Clevelox; Cleviprex; H 324/38; rac-Clevidipine. CAS No. 167221-71-8. Pack Sizes: 250 mg. Product ID: NP3328. Molecular formula: C21H23Cl2NO6. Mole weight: 456.32. Custom synthesis is available. Send your inquiries for more information.
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Clevidipine Impurity 4
Clevidipine Impurity 4 is an impurity of Clevidipine, a therapeutic drug primarily for treating hypertension and treating arteriosclerosis. Group: Pharmaceutical. Alternative Names: 3-Pyridinecarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, methyl ester; Methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3-pyridinecarboxylate; H 168/79; 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3-pyridinecarboxylic acid methyl ester. CAS No. 253597-20-5. Pack Sizes: 10 mg. Product ID: B0630-469134. Molecular formula: C15H15Cl2NO2. Mole weight: 312.19. Custom synthesis is available. Send your inquiries for more information.
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Clonidine EP Impurity B
Acetylcholidine is an impurity in the synthesis of Clonidine, an α2-Adrenergic agonist. Group: Pharmaceutical. Alternative Names: acetylclonidine; Clonidine Related Compound A; 1-(2-((2,6-Dichlorophenyl)amino)-4,5-dihydro-1H-imidazol-1-yl)ethan-1-one; 1-Acetyl-2-(2,6-dichlorophenylimino)-imidazolidine). CAS No. 54707-71-0. Pack Sizes: 100 mg. Product ID: B1370-159651. Molecular formula: C11H11Cl2N3O. Mole weight: 272.13. Custom synthesis is available. Send your inquiries for more information.
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Dasotraline hydrochloride
Dasotraline hydrochloride, also called as SEP-225289 hydrochloride, is a metabolite of Sertraline and a novel inhibitor of dopamine and norepinephrine reuptake that blocks dopamine, norepinephrine, andserotonin transporters (IC50 = 4, 6, and 11 nM, respectively). Group: Pharmaceutical. Alternative Names: (1R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride; SEP-225,289; SEP225,289; SEP225,289; SEP-225289; SEP225289; SEP225289;; Dasotraline; Dasotraline HCl; Dasotraline hydrochloride. CAS No. 675126-08-6. Pack Sizes: 5 mg. Product ID: B0084-241506. Molecular formula: C16H16Cl3N. Mole weight: 328.66. Custom synthesis is available. Send your inquiries for more information.
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Dichlormate
Dichlormate is a herbicide. Group: Pharmaceutical. Alternative Names: Sirmate; 3,4-Sirmate; 3,4-Dichlorobenzyl methylcarbamate; (3,4-dichlorophenyl)methyl N-methylcarbamate. CAS No. 1966-58-1. Pack Sizes: 100 mg. Product ID: B0046-263631. Molecular formula: C9H9Cl2NO2. Mole weight: 234.08. Custom synthesis is available. Send your inquiries for more information.
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Diclofenac EP Impurity C
Diclofenac EP Impurity C is an impurity of Diclofenac, which is a non-selective COX inhibitor used as a non-steroidal anti-inflammatory drug (NSAID). Group: Pharmaceutical. Alternative Names: Diclofenac sodium EP impurity C; Diclofenac potassium EP impurity C; Diclofenac Impurity C; [2-[(2,6-dichlorophenyl)amino]phenyl]methanol; 2-[(2,6-Dichlorophenyl)amino]benzenemethanol; Diclofenac Alcohol (Diclofenac Impurity); Benzenemethanol, 2-[(2,6-dichlorophenyl)amino]-; Benzyl alcohol, o-(2,6-dichloroanilino)-; Diclofenac alcohol analog. CAS No. 27204-57-5. Pack Sizes: 100 mg. Product ID: B2694-470082. Molecular formula: C13H11Cl2NO. Mole weight: 268.14. Custom synthesis is available. Send your inquiries for more information.
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Diclofenac Potassium
Diclofenac potassium is a nonsteroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and as an analgesic reducing pain in certain conditions. It is a competitive inhibitor of cyclooxygenase (COX) that suppresses the production of prostaglandins. Diclofenac potassium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade. Uses: Nsaid. Group: Pharmaceutical. Alternative Names: 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Potassium Salt; [o-(2,6-Dichloroanilino)phenyl]acetic Acid Monopotassium Salt; 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Monopotassium Salt; Caflam; Cataflam; K-fenak; Potassium diclofenac. CAS No. 15307-81-0. Pack Sizes: 20 g. Product ID: B0084-059596. Molecular formula: C14H10Cl2KNO2. Mole weight: 334.24. Custom synthesis is available. Send your inquiries for more information.
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Dicloxacillin
Dicloxacillin, a β-lactamase resistant penicillin similar to oxacillin, used to treat infections caused by susceptible (non-resistant) Gram-positive bacteria. Uses: Used as an antibiotic especially against gram-positive bacteria and also be significant in biological studies. Group: Pharmaceutical. Alternative Names: Veracillin, BRL1702; BRL 1702; BRL-1702;(2S,5R,6R)-6-[[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. CAS No. 3116-76-5. Pack Sizes: 1mg;1g;10g. Product ID: BBF-01839. Molecular formula: C19H17Cl2N3O5S. Mole weight: 470.32. Custom synthesis is available. Send your inquiries for more information.
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Econazolum
Econazole, structurally similar to miconazole, is an effective antifungal drug. Group: Pharmaceutical. Alternative Names: 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole; Econazole; Econazole Nitrate; Ekonazole; Gyno Pervaryl 150; Gyno Pevaril; Gyno Pevaryl; Gyno-Pervaryl 150; Gyno-Pevaril; Gyno-Pevaryl; GynoPevaril;Nitrate, Econazole; Pevaryl. CAS No. 27220-47-9. Pack Sizes: 1mg;1g;10g. Product ID: 27220-47-9. Molecular formula: C18H15Cl3N2O. Mole weight: 381.68. Custom synthesis is available. Send your inquiries for more information.
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Fluralaner
Fluralaner is a systemic insecticide and acaricide. It can be used for flea treatment in dogs. Uses: Flea treatment in dogs. Group: Pharmaceutical. Alternative Names: AH252723; AH-252723; AH 252723; A-1443; A1443; A 1443; Fluralaner, trade name: Bravecto. 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-2-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]benzamide. CAS No. 864731-61-3. Pack Sizes: 100 mg. Product ID: B0084-476691. Molecular formula: C22H17Cl2F6N3O3. Mole weight: 556.29. Custom synthesis is available. Send your inquiries for more information.
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Fluxametamide
Fluxametamide, a broad-spectrum insecticide, is an antagonist of GABA- and glutamate-gated chloride channels, with IC50s of 1.95 and 225 nM for M. domestica GABACls and GluCls. Group: Pharmaceutical. Alternative Names: 4-(5-(3,5-Dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl)-N-((methoxyimino)methyl)-2-methylbenzamide; Benzamide, 4-(5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl)-N-((methoxyamino)methylene)-2-methyl-; 4-[5-(3,5-Dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-1,2-oxazol-3-yl]-N-[(methoxyimino)methyl]-o-toluamide. CAS No. 928783-29-3. Pack Sizes: 500 mg. Product ID: B1370-381842. Molecular formula: C20H16Cl2F3N3O3. Mole weight: 474.26. Custom synthesis is available. Send your inquiries for more information.
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GSK1016790A
GSK1016790A is a novel and potent transient receptor potential vanilloid 4 (TRPV4) agonist. It has been used to demonstrate a role for TRPV4 in regulating urinary bladder activity and endothelial control of vascular tone. It elicited Ca2+ influx in mouse and human TRPV4 expressing HEK cells with EC50 values of 18 and 2.1 nM, respectively. It also evoked a dose-dependent activation of TRPV4 whole-cell currents at concentrations above 1 nM, which is 300 fold more potent than 4a-PDD. It was developed by GlaxoSmithKline. Uses: Gsk1016790a regulats urinary bladder activity and endothelial control of vascular tone. Group: Pharmaceutical. Alternative Names: GSK1016790A; GSK-1016790A; GSK 1016790A. N-((S)-1-(4-((S)-2-(2,4-dichlorophenylsulfonaMido)-3-hydroxypropanoyl)piperazin-1-yl)-4-Methyl-1-oxopentan-2-yl)benzo[b]thiophene-2-carboxaMide. CAS No. 942206-85-1. Pack Sizes: 100 mg. Product ID: B0084-382782. Molecular formula: C28H32Cl2N4O6S2. Mole weight: 655.61. Custom synthesis is available. Send your inquiries for more information.
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Guanfacine hydrochloride
Guanfacine, a selective agonist of α2A receptor, is a sympatholytic drug to treat attention deficit hyperactivity disorder (ADHD) and hypertension. It lowers both systolic and diastolic blood pressure. Group: Pharmaceutical. Alternative Names: BS 100-141; Tenex; Estulic; Guanfacine HCl; N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide hydrochloride; N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide hydrochloride; N-Amidino-2-(2,6-dichlorophenyl)acetamide hydrochloride; Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, hydrochloride (1:1). CAS No. 29110-48-3. Pack Sizes: 500 mg. Product ID: B0084-065259. Molecular formula: C9H10Cl3N3O. Mole weight: 282.56. Custom synthesis is available. Send your inquiries for more information.
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Hydroxy Itraconazole
A metabolite of Itraconazole, an orally active antimycotic structurally related to Ketoconazole. Uses: Hydroxy itraconazole is a metabolite of itraconazole and could be used as an antimycotic. Group: Pharmaceutical. Alternative Names: 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(2-hydroxy-1-methylpropyl)-3H-1,2,4-triazol-3-one. CAS No. 112559-91-8. Pack Sizes: 5 mg. Product ID: B0214-232323. Molecular formula: C35H38Cl2N8O5. Mole weight: 721.65. Custom synthesis is available. Send your inquiries for more information.
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JPH203
JPH203 is a potent and selective L-type amino acid transporter 1 (LAT1) inhibitor. It inhibits 14C-leucine uptake and cell growth in human colon cancer-derived HT-29 cells in vitro. It also inhibits 14C-leucine uptake in mouse renal proximal tubule cells expressing l-type amino acid transporter 1, and inhibits cell growth. It completely inhibits the proliferation of YD-38 cells in a dose- and time-dependent manner. It suppresses proliferation in cancer cell lines and is used for cancer research. It was developed by J-Pharma and in clinic phase 1 trials. Uses: Jph203 suppresses proliferation in cancer cell lines and is used for cancer research. Group: Pharmaceutical. Alternative Names: KYT-0353;KYT0353;JPH-203; KYT 0353;JPH 203;(S)-2-amino-3-(4-((5-amino-2-phenylbenzo[d]oxazol-7-yl)methoxy)-3,5-dichlorophenyl)propanoic acid. CAS No. 1037592-40-7. Pack Sizes: 10 mg. Product ID: B0084-474997. Molecular formula: C23H19Cl2N3O. Mole weight: 472.32. Custom synthesis is available. Send your inquiries for more information.
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Ketoconazole EP Impurity C
Ketoconazole EP Impurity C is an impurity of Ketoconazole, which is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. Group: Pharmaceutical. Alternative Names: 1-Acetyl-4-[4-[[(2RS,4RS)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-piperazine; rac-trans-Ketoconazole; Piperazine, 1-Acetyl-4-[4-[[(2R,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-, rel-; Piperazine, 1-acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-, trans-; rel-1-Acetyl-4-[4-[[(2R,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine; R 44319; RS 36745; trans-Ketoconazole; Ketoconazole Impurity C. CAS No. 83374-59-8. Pack Sizes: 5 mg. Product ID: B1270-120523. Molecular formula: C26H28Cl2N4O4. Mole weight: 531.43. Custom synthesis is available. Send your inquiries for more information.
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Loflucarban
Loflucarban is an antifungal agent. Group: Pharmaceutical. Alternative Names: Loflucarban; NSC 76851; NSC-76851; NSC76851; Fluonilid; Fluonilide; 3,5-Dichloro-4'-fluorothiocarbanilide; 1-(3,5-dichlorophenyl)-3-(4-fluorophenyl)thiourea. CAS No. 790-69-2. Pack Sizes: 25 mg. Product ID: B0084-284860. Molecular formula: C13H9Cl2FN2S. Mole weight: 315.187. Custom synthesis is available. Send your inquiries for more information.
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Lvguidingan
Lvguidingan is an antiepileptic drug. Group: Pharmaceutical. Alternative Names: Anticonvulsant 7903; N-(Butan-2-yl)-3-(3,4-dichlorophenyl)prop-2-enamide; 3,4-Dichlorophenyl propenylisobutylamide; 3,4-Dichlorophenylpropenoyl isobutylamide. CAS No. 82351-05-1. Pack Sizes: 50 mg. Product ID: B0084-284835. Molecular formula: C13H15Cl2NO. Mole weight: 272.169. Custom synthesis is available. Send your inquiries for more information.
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LY-2562175
LY2562175 is a potent and selective FXR agonist in vitro. It has robust lipid modulating properties, lowering LDL and triglycerides while raising HDL in preclinical species. It was developed by Eli Lilly and Company and in clinic phase 1 trials with no progress. Uses: Ly2562175 has robust lipid modulating properties, lowering ldl and triglycerides while raising hdl in preclinical species. Group: Pharmaceutical. Alternative Names: LY2562175; LY 2562175; LY-2562175;6-(4-((5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic acid. CAS No. 1103500-20-4. Pack Sizes: 10 mg. Product ID: B2693-475063. Molecular formula: C28H27Cl2N3O4. Mole weight: 540.44. Custom synthesis is available. Send your inquiries for more information.
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Miconazole nitrate
Miconazole nitrate is an imidazole antifungal agent that blocks ergosterol biosynthesis. It is commonly used as a topical drug for skin infections. It promotes the differentiation of mature oligodendrocytes from progenitor cells. Uses: 14-alpha demethylase inhibitors. Group: Pharmaceutical. Alternative Names: Albistat; Andergin; Aflorix; 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole nitrate; [2,4-Dichloro-β-(2,4-dichlorobenzyloxy)phenethyl]imidazole Nitrate; Brentan; Conoderm; Conofite; Daktacort; Florid; Fungiderm; Fungisdin; Micatin; Miconal; Zimycan. CAS No. 22832-87-7. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04480. Molecular formula: C18H15Cl4N3O4. Mole weight: 479.14. Custom synthesis is available. Send your inquiries for more information.
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Nitroso-sertraline-[d3] (cis racemic mixture)
Nitroso-sertraline-[d3] (cis racemic mixture) is a labelled analogue of nitroso-sertraline. Nitroso-sertraline is undergoing extensive first-pass metabolism by cytochrome P450 and selectively inhibits the reuptake of serotonin at the presynaptic neuronal membrane that is used to treat the major depressive disorder, a social anxiety disorder. Group: Pharmaceutical. Alternative Names: N-((1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl)-N-(methyl-d3)nitrous amide; Nitroso-sertraline-d3 (cis racemic mixture). Pack Sizes: 10 mg. Product ID: BLP-014819. Molecular formula: C17H13D3Cl2N2O. Mole weight: 338.25. Custom synthesis is available. Send your inquiries for more information.
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N-Nitroso Sertraline
N-Nitroso Sertraline is an impurity of Sertraline, a selective serotonin reuptake inhibitor (SSRI) used to treat certain mental disorders. Group: Pharmaceutical. Alternative Names: 1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-N-nitroso-, (1S,4S)-. CAS No. 3006789-98-3. Pack Sizes: 10 mg. Product ID: B1370-449583. Molecular formula: C17H16Cl2N2O. Mole weight: 335.23. Custom synthesis is available. Send your inquiries for more information.
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N-Nitroso Sertraline-[d3]
N-Nitroso Sertraline-[d3] is a deuterated compound of N-Nitroso Sertraline. N-Nitroso Sertraline is an impurity of Sertraline, a selective serotonin reuptake inhibitor (SSRI) used to treat certain mental disorders. Group: Pharmaceutical. Alternative Names: N-((1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl)-N-(methyl-d3)nitrous amide. Pack Sizes: 10 mg. Product ID: BLP-015173. Molecular formula: C17H13D3Cl2N2O. Mole weight: 338.25. Custom synthesis is available. Send your inquiries for more information.
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Olanexidine hydrochloride semihydrate
Olanexidine is a monobiguanide analog with bactericidal activity. Group: Pharmaceutical. Alternative Names: OPB-2045; OPB-2045G; 1-[N'-[(3,4-dichlorophenyl)methyl]carbamimidoyl]-2-octylguanidine hydrate dihydrochloride. CAS No. 218282-71-4. Pack Sizes: 1mg;1g;10g. Product ID: 218282-71-4. Molecular formula: C17H29Cl3N5O1/2. Mole weight: 417.8. Custom synthesis is available. Send your inquiries for more information.
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PF-8380
PF-8380 blocks inflammation-induced LPA synthesis. PF-8380 works both in vitro and in vivo through direct inhibition of autotaxin. In human whole blood PF-8380 inhibited autotaxin with an IC50 of 101 nM. Inhibition of ATX by PF-8380 led to decreased invasion and enhanced radiosensitization of GBM cells. Radiation-induced activation of Akt was abrogated by inhibition of ATX. Furthermore, inhibition of ATX led to diminished tumor vascularity and delayed tumor growth. PF-8380 can serve as a tool compound for elucidating LPA's role in inflammation. Group: Pharmaceutical. Alternative Names: 1-Piperazinecarboxylic acid, 4-[3-(2,3-dihydro-2-oxo-6-benzoxazolyl)-3-oxopropyl]-, (3,5-dichlorophenyl)methyl ester; PF8380; PF 8380; (3,5-Dichlorophenyl)methyl 4-[3-(2,3-dihydro-2-oxo-6-benzoxazolyl)-3-oxopropyl]-1-piperazinecarboxylate; 4-[3-Oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]piperazine-1-carboxylic acid 3,5-dichlorobenzyl ester. CAS No. 1144035-53-9. Pack Sizes: 100 mg. Product ID: B2693-457060. Molecular formula: C22H21Cl2N3O5. Mole weight: 478.33. Custom synthesis is available. Send your inquiries for more information.
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Procymidone
Procymidone is a pesticide. It can be used for killing unwanted ferns and nettles, and as a dicarboximide fungicide for killing fungi. Uses: Fungicides, industrial. Group: Pharmaceutical. Alternative Names: 1,2-Dimethyl-N-(3,5-dichlorophenyl)cyclopropanedicarboximide; Dicyclidine; Dicyclidine; Kenolex; Procilex; Procymidone; Procymidor; Procymidox; Salithiex; Sialex; Sumilex; Sumilex; Sumisclex. CAS No. 32809-16-8. Pack Sizes: 5 g. Product ID: B2692-090248. Molecular formula: C13H11Cl2NO2. Mole weight: 284.14. Custom synthesis is available. Send your inquiries for more information.
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Rimonabant Hydrochloride
Rimonabant Hydrochloride, used as a tool to investigate CB receptor properties, it is a selective antagonist of cannabinoid CB1 receptor (Ki = 1.98 nM) and inverses adenylyl cyclase inhibition (IC50 = 48 nM). Uses: A brain cannabinoid receptor (cb1) antagonist. antiobesity agent. Group: Pharmaceutical. Alternative Names: 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide; Rimonabant free base, SR141716; SR 141716; SR-141716; A 281; A-281; A281; Rimonabant, Acomplia, Zimulti. CAS No. 158681-13-1. Pack Sizes: 500 mg. Product ID: B0084-085024. Molecular formula: C22H21Cl3N4O.HCl. Mole weight: 500.25. Custom synthesis is available. Send your inquiries for more information.
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(S)-2,4-Dichloro-a-methyl-benzenemethanamine
(S)-2,4-Dichloro-a-methyl-benzenemethanamine. Group: Pharmaceutical. Alternative Names: (S)-1-(2,4-Dichlorophenyl)ethanamine; Benzenemethanamine, 2,4-dichloro-α-methyl-, (αS)-; (1S)-1-(2,4-dichlorophenyl)ethan-1-amine. CAS No. 133492-69-0. Pack Sizes: 1 g. Product ID: B1370-164007. Molecular formula: C8H9Cl2N. Mole weight: 190.07. Custom synthesis is available. Send your inquiries for more information.
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Sertraline 2,3-Dichloro Ketone Impurity
An impurity of sertraline. Sertraline is a selective serotonin reuptake inhibitor (SSRI) for the treatment of depression. Group: Pharmaceutical. Alternative Names: 4-(2,3-Dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone; rac 4-(2,3-Dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone. CAS No. 152448-80-1. Pack Sizes: 200 mg. Product ID: B0186-260624. Molecular formula: C16H12Cl2O. Mole weight: 291.17. Custom synthesis is available. Send your inquiries for more information.
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SHP099
SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 value 0.071 μM) that stabilizes SHP2 in an auto-inhibited conformation. SHP099 suppresses signaling through the Ras-ERK pathway and blocks the proliferation of receptor tyrosine kinase-driven human cancer cells in vitro and in vivo. Group: Pharmaceutical. Alternative Names: 6-(4-amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine; SHP099; SHP-099; SHP 099. CAS No. 1801747-42-1. Pack Sizes: 20 mg. Product ID: B0084-007855. Molecular formula: C16H19Cl2N5. Mole weight: 352.26. Custom synthesis is available. Send your inquiries for more information.
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SHP099 HCl
SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 value 0.071 μM) that stabilizes SHP2 in an auto-inhibited conformation. SHP099 suppresses signaling through the Ras-ERK pathway and blocks the proliferation of receptor tyrosine kinase-driven human cancer cells in vitro and in vivo. Group: Pharmaceutical. Alternative Names: 6-(4-amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine hydrochloride; SHP099; SHP-099; SHP 099. SHP-099 hydrochloride, SHP-099 HCl. CAS No. 1801747-11-4. Pack Sizes: 500 mg. Product ID: B2693-007852. Molecular formula: C16H20Cl3N5. Mole weight: 388.72. Custom synthesis is available. Send your inquiries for more information.
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SU 5201
SU 5201 is an inhibitor of IL-2 production. Group: Pharmaceutical. Alternative Names: (3Z)-3-[(3,4-Dichlorophenyl)methylidene]-1H-indol-2-one; NSC 247030; NSC-247030; NSC247030; SU 5201; SU5201; SU-5201. CAS No. 114727-43-4. Pack Sizes: 50 mg. Product ID: B0084-284849. Molecular formula: C15H9Cl2NO. Mole weight: 290.143. Custom synthesis is available. Send your inquiries for more information.
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Terconazole
Terconazole is an antifungal drug used to treat vaginal yeast infection. It has a relatively broad spectrum compared to azole compounds. It may exert its antifungal activity by disrupting normal fungal cell membrane permeability. It comes as a lotion or a suppository and disrupts the biosynthesis of fats in a yeast cell. It is a suitable compound for prophylaxis for those that suffer from chronic vulvovaginal candidiasis. It has a far greater selectively for yeast cytochrome P-450 than for mammalian microsomal cytochrome P-450. It may also be used in vitro to prevent the morphogenetic transformation of yeast into (pseudo-)mycelium form of Candida albicans. It was developed by Johnson & Johnson and has been listed. Uses: Terconazole is an antifungal drug used to treat vaginal yeast infection. it may also be used in vitro to prevent the morphogenetic transformation of yeast into (pseudo-)mycelium form of candida albicans. Group: Pharmaceutical. Alternative Names: Piperazine, 1-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylethyl)-, cis-; cis-1-(p-{[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine; Piperazine, 1-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylethyl)-, rel-; r. CAS No. 67915-31-5. Pack Sizes: 500 mg. Product ID: B0084-400393. MolecÂ…
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Tioconazole Related Compound A
One impurity of Tioconazole, which could be used as an antifungal agent and exhibit activities against Candida glabrata mutant strains. Group: Pharmaceutical. Alternative Names: 2-Deschlorothien-3-yl Tioconazole Hydrochloride; 1-[2-(2,4-Dichlorophenyl)-2-(3-thienylmethoxy)ethyl]-1H-imidazole Monohydrochloride. CAS No. 61709-33-9. Pack Sizes: 1 g. Product ID: B1370-484193. Molecular formula: C16H14Cl2N2OS. HCl. Mole weight: 389.73. Custom synthesis is available. Send your inquiries for more information.
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VER-155008
VER-155008 is an adenosine-derived inhibitor of heat shock protein 70 (Hsp70; IC50 = 0.5 μM) that is selective over Hsp90. It targets the nucleotide-binding domain (NBD) of Hsp70 and similarly binds the NBDs of Hsp70 cognates Hsc70 (Ki = 10 μM) and glucose-regulated protein 78 (Grp78; KD = 80 nM). VER-155008 inhibits the proliferation of human breast and colon cancer cell lines, inducing apoptosis or caspase-independent cell death. It induces the proteasome-dependent degradation of Hsp90 client proteins and potentiates the apoptotic activity of Hsp90 inhibitors. VER-15508 also triggers paraptosis in anaplastic thyroid carcinoma cells. Group: Pharmaceutical. Alternative Names: 8-(3,4-Dichlorobenzyl)amino-5'-O-(4-cyanobenzyl)adenosine; C07; VER 155008; VER155008; 5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-Adenosine; 4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile. CAS No. 1134156-31-2. Pack Sizes: 100 mg. Product ID: B1370-272446. Molecular formula: C25H23Cl2N7O4. Mole weight: 556.4. Custom synthesis is available. Send your inquiries for more information.
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