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| Product | Description | |
|---|---|---|
| Desmethyl Celecoxib | An impurity of Celecoxib, which is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits COX-2. Group: Pharmaceutical. CAS No. 170569-87-6. Pack Sizes: 100 mg. Product ID: B0070-468630. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Desmethyl Erlotinib | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Group: Pharmaceutical. CAS No. 183321-86-0. Pack Sizes: 5 mg. Product ID: B2694-263407. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Desmethyl Etoricoxib | An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Group: Pharmaceutical. CAS No. 202409-31-2. Pack Sizes: 100 mg. Product ID: B2694-471299. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Desmethyl Telmisartan | One of the impurities of Telmisartan, which is an angiotensin II receptor antagonist and could be used in the treatment of hypertensive. Group: Pharmaceutical. CAS No. 144701-81-5. Pack Sizes: 5 mg. Product ID: B2694-483012. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Desmethyl-2-methyl Celecoxib | 4-Desmethyl-2-methyl Celecoxib is an analog of Celecoxib, a cyclooxygenase 2 inhibitor. Group: Pharmaceutical. CAS No. 170569-99-0. Pack Sizes: 100 mg. Product ID: B2694-468625. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-O-Desmethyl Omeprazole | 5-O-Desmethyl Omeprazole is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Uses: A metabolite of omeprazole, an antiulcerative. Group: Pharmaceutical. CAS No. 151602-49-2. Pack Sizes: 10 mg. Product ID: B1370-050380. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 6-O-Desmethyl Donepezil | A metabolite of Donepezil, a medication for the treatment of Alzheimer's disease. Group: Pharmaceutical. CAS No. 120013-56-1. Pack Sizes: 25 mg. Product ID: B2694-470362. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetamiprid-N-Desmethyl-[Acetimidamide-13C2,amine-15N] | Acetamiprid-N-Desmethyl-[Acetimidamide-13C2,amine-15N]. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-007161. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Desvenlafaxine (O-Desmethyl Venlafaxine) Succinate Monohydrate | Desvenlafaxine Succinate is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively. Group: Pharmaceutical. CAS No. 386750-22-7. Pack Sizes: 5 g. Product ID: B2693-067733. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Didesmethyl chlorpromazine HCl | Didesmethylchlorpromazine Hydrochloride is an impurity of Chlorpromazine, an antipsychotic medication used for the treatment of psychotic disorders such as schizophrenia. Group: Pharmaceutical. CAS No. 3763-80-2. Pack Sizes: 100 mg. Product ID: B0598-284951. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Erlotinib O-Desmethyl Metabolite Isomer (M14) HCl | OSI-420 (CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells. Uses: For research used only. Group: Pharmaceutical. CAS No. 183320-51-6. Pack Sizes: 10 mg. Product ID: B0084-286627. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Azelastine | N-Desmethyl Azelastine is the main metabolite of Azelastine. Azelastine is a potent, selective and second-generation histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor. Group: Pharmaceutical. CAS No. 47491-38-3. Pack Sizes: 50 mg. Product ID: B2694-467139. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Citalopram Oxalate | An impurity of Citalopram, an antidepressant of the selective serotonin reuptake inhibitor class. Group: Pharmaceutical. CAS No. 62498-68-4. Pack Sizes: 10 mg. Product ID: B1370-105942. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Enzalutamide | N-desmethyl Enzalutamide is a major metabolite of Enzalutamide. Enzalutamide is an androgen-receptor (AR) antagonist (IC50 = 36 nM) in LNCaP cells that inhibits the transcriptional activity of a mutant AR protein. Enzalutamide resists against induction of prostate-specific antigen (PSA) and transmembrane serine protease 2 (TMPRSS2). N-desmethyl Enzalutamide can be used for the treatment of disorders involving androgen, estrogen and progesterone receptors. Uses: The treatment of disorders involving androgen, estrogen and progesterone receptors. Group: Pharmaceutical. CAS No. 1242137-16-1. Pack Sizes: 20 mg. Product ID: B0084-474425. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Imatinib | A metabolite of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Group: Pharmaceutical. CAS No. 404844-02-6. Pack Sizes: 10 mg. Product ID: B2694-473156. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Imatinib-[d8] | N-Desmethyl Imatinib-[d8] is a deuterated metabolite of gleevec, a tyrosine kinase inhibitor specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). Group: Pharmaceutical. CAS No. 1185103-28-9. Pack Sizes: 5 mg. Product ID: BLP-009648. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyltamoxifen | N-Desmethyltamoxifen is a metabolite of tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Group: Pharmaceutical. CAS No. 31750-48-8. Pack Sizes: 1 g. Product ID: B1370-107540. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Tamoxifen-[d5] | An isotope labelled metabolite of Tamoxifen. Tamoxifen is a medication that is used to treat breast cancer. Group: Pharmaceutical. CAS No. 164365-16-6. Pack Sizes: 5 mg. Product ID: BLP-013914. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Tamoxifen HCl | One of the impurities of Tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Group: Pharmaceutical. CAS No. 15917-65-4. Pack Sizes: 100 mg. Product ID: B1370-260466. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Ulipristal Acetate | N-Desmethyl Ulipristal Acetate is a metabolite of Ulipristal. Ulipristal is a selective progesterone receptor modulator (SPRM) used for emergency contraception and uterine fibroid. Group: Pharmaceutical. CAS No. 159681-66-0. Pack Sizes: 100 mg. Product ID: B1917-452616. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Vandetanib | N-Desmethyl Vandetanib is a metabolite of Vandetanib. Vandetanib is an antitumor drug used for the treatment of medullary thyroid cancer. Vandetanib effects through inhibiting vascular endothelial growth factor receptor-2 (VEGFR), epidermal growth factor receptor (EGFR) and the RET-tyrosine kinase activity. Group: Pharmaceutical. CAS No. 338992-12-4. Pack Sizes: 5 mg. Product ID: B1926-260255. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| O-Desmethyl Apixaban | A metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Group: Pharmaceutical. CAS No. 503612-76-8. Pack Sizes: 100 mg. Product ID: B2694-466672. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| O-Desmethyl Venlafaxine Cyclic Impurity | O-Desmethyl Venlafaxine Cyclic Impurity is a cyclic impurity of O-Desmethylvenlafaxine. Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. Group: Pharmaceutical. CAS No. 1346601-55-5. Pack Sizes: 10 mg. Product ID: B2694-485086. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| rac-N-Desmethyl Bedaquiline | rac-N-Desmethyl Bedaquiline is an intermediate used in th synthesis of Bedaquiline, a medication approved for the treatment of active tuberculosis. Group: Pharmaceutical. CAS No. 654654-76-9. Pack Sizes: 1 g. Product ID: B2692-007095. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| α,α,α',5-Tetramethyl-1, 3- benzenediacetonitril e | α,α,α',5-Tetramethyl-1, 3- benzenediacetonitril e is an intermediate in the synthesis of α-Desmethyl Anastrozole. Group: Pharmaceutical. CAS No. 120512-38-1. Pack Sizes: 100 mg. Product ID: BB076990. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lasofoxifene | Lasofoxifene (INN) (proposed tradename Fablyn) is a non-steroidal selective estrogen receptor modulator (SERM) which is under development by Pfizer for the prevention and treatment of osteoporosis and for the treatment of vaginal atrophy, and the result of an exclusive research collaboration with Ligand Pharmaceuticals (LGND). In September 2005, Pfizer received a non-approvable letter from the U.S. Food and Drug Administration regarding lasofoxifene ( Oporia), a selective estrogen receptor modulator for the prevention of osteoporosis. Lasofoxifene was approved in the EU under the Fablyn by the EMEA in March 2009. Lasofoxifene is a desmethyl dihydro analog of nafoxidine. Group: Pharmaceutical. CAS No. 180916-16-9. Pack Sizes: 100 mg. Product ID: B2693-465309. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Metoprolol Impurity A | C-Desmethyl Metoprolol is a new byproduct detected in Metoprolol tartrate. It is a Metoprolol impurity. Group: Pharmaceutical. CAS No. 109632-08-8. Pack Sizes: 50 mg. Product ID: B2694-260444. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Metoprolol Impurity H | O-Desmethyl Metoprolol is a metabolite of Metoprolol. Group: Pharmaceutical. CAS No. 62572-94-5. Pack Sizes: 100 mg. Product ID: B0151-260445. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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