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| Product | Description | |
|---|---|---|
| Desmethyl Celecoxib | An impurity of Celecoxib, which is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits COX-2. Group: Pharmaceutical. Alternative Names: 4-[5-Phenyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide. CAS No. 170569-87-6. Pack Sizes: 100 mg. Product ID: B0070-468630. Molecular formula: C16H12F3N3O2S. Mole weight: 367.346. Custom synthesis is available. Send your inquiries for more information. |  London |
| Desmethyl Erlotinib | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Group: Pharmaceutical. Alternative Names: 2-[[4-[(3-Ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]ethanol. CAS No. 183321-86-0. Pack Sizes: 5 mg. Product ID: B2694-263407. Molecular formula: C21H21N3O4. Mole weight: 379.42. Custom synthesis is available. Send your inquiries for more information. | London |
| Desmethyl Etoricoxib | An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Group: Pharmaceutical. Alternative Names: 5-Chloro-3-(4-methylsulfonylphenyl)-2-(3-pyridyl)pyridine. CAS No. 202409-31-2. Pack Sizes: 100 mg. Product ID: B2694-471299. Molecular formula: C17H13ClN2O2S. Mole weight: 344.82. Custom synthesis is available. Send your inquiries for more information. | London |
| Desmethyl Telmisartan | One of the impurities of Telmisartan, which is an angiotensin II receptor antagonist and could be used in the treatment of hypertensive. Group: Pharmaceutical. Alternative Names: N-Desmethyl telmisartan; 4'-[(4'Methyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid. CAS No. 144701-81-5. Pack Sizes: 5 mg. Product ID: B2694-483012. Molecular formula: C32H28N4O2. Mole weight: 500.61. Custom synthesis is available. Send your inquiries for more information. | London |
| 13-O-Desmethyl Tacrolimus | 13-O-Desmethyl Tacrolimus is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Group: Pharmaceutical. Alternative Names: (3S,4R,5S,8R,9E,12S,14S,15S,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26-Hexadecahydro-5,16,19-trihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14-methoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-16,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone. CAS No. 139958-51-3. Pack Sizes: 5 mg. Product ID: B1370-386089. Molecular formula: C43H67NO12. Mole weight: 789.99. Custom synthesis is available. Send your inquiries for more information. | London |
| 27-O-Desmethyl Rapamycin (27-O-Desmethyl Sirolimus) | A metabolite of Rapamycin. Rapamycin is a macrolide compound. It inhibits activation of T cells and B cells by reducing the production of interleukin-2. Rapamycin can be used to coat coronary stents and prevent organ transplant rejection. Group: Pharmaceutical. Pack Sizes: 1mg;1g;10g. Molecular formula: C50H77NO13. Mole weight: 900.17. Custom synthesis is available. Send your inquiries for more information. | London |
| 32-Desmethylrapamycin | 32-Desmethylrapamycin is a rapamycin derivative with antifungal activity. It is active against Candida albicans, Saccharomyces cerevisiae and Fusarium oxysporum. Group: Pharmaceutical. Alternative Names: 32-O-Desmethylrapamycin; Rapamycin, 32-O-demethyl-. CAS No. 141392-23-6. Pack Sizes: 5 mg. Product ID: B1370-381780. Molecular formula: C50H77NO13. Mole weight: 900.15. Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Desmethyl-2-methyl Celecoxib | 4-Desmethyl-2-methyl Celecoxib is an analog of Celecoxib, a cyclooxygenase 2 inhibitor. Group: Pharmaceutical. Alternative Names: 4-[5-(2-Methylphenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide; Celecoxib 2-Methyl Analog; 4-(5-o-Tolyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide. CAS No. 170569-99-0. Pack Sizes: 100 mg. Product ID: B2694-468625. Molecular formula: C17H14F3N3O2S. Mole weight: 381.38. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-O-Desmethyl Omeprazole | 5-O-Desmethyl Omeprazole is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Uses: A metabolite of omeprazole, an antiulcerative. Group: Pharmaceutical. Alternative Names: 1H-Benzimidazol-6-ol, 2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-; 1H-Benzimidazol-5-ol, 2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-; 2-[[(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazol-6-ol; 5-O-Desmethylomeprazole. CAS No. 151602-49-2. Pack Sizes: 10 mg. Product ID: B1370-050380. Molecular formula: C16H17N3O3S. Mole weight: 331.39. Custom synthesis is available. Send your inquiries for more information. | London |
| 6-O-Desmethyl Donepezil | A metabolite of Donepezil, a medication for the treatment of Alzheimer's disease. Group: Pharmaceutical. Alternative Names: 1-Benzyl-4-[(6-hydroxy-5-methoxy-1-oxo-indan-2-yl)methylpiperidine; 2,3-Dihydro-6-hydroxy-5-methoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one. CAS No. 120013-56-1. Pack Sizes: 25 mg. Product ID: B2694-470362. Molecular formula: C23H27NO3. Mole weight: 365.47. Custom synthesis is available. Send your inquiries for more information. | London |
| 7-O-Desmethyl Rapamycin | A metabolite of Rapamycin. Rapamycin is a macrolide compound. It inhibits activation of T cells and B cells by reducing the production of interleukin-2. Rapamycin can be used to coat coronary stents and prevent organ transplant rejection. Group: Pharmaceutical. Alternative Names: 7-O-Demethyl Cypher; 7-O-Demethyl Rapammune; 7-O-Demethyl Sirolimus. CAS No. 151519-50-5. Pack Sizes: 1mg;1g;10g. Product ID: 151519-50-5. Molecular formula: C50H77NO13. Mole weight: 900.17. Custom synthesis is available. Send your inquiries for more information. | London |
| 8-desmethylmilbemycin A4 oxime | 8-desmethylmilbemycin A4 oxime is a derivative of Milbemycin, a group of macrolides originaly isolated from Streptomyces hygroscopicus. Milbemycins are used in veterinary field for antiparasitic activity. Group: Pharmaceutical. Alternative Names: Milbemycin oxime EP Impurity H; 11'-Desmethylmilbemycin A4 oxime. Pack Sizes: 1mg;1g;10g. Product ID: BBF-05923. Molecular formula: C31H43NO7. Mole weight: 541.69. Custom synthesis is available. Send your inquiries for more information. | London |
| Desvenlafaxine (O-Desmethyl Venlafaxine) Succinate Monohydrate | Desvenlafaxine Succinate is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively. Group: Pharmaceutical. Alternative Names: Pristiq; Desvenlafaxine succinate hydrate; 4-[2-(Dimethylamino)-1-(1-hydroxycy clohexyl)ethyl]phenol succinate; WY 45233 Succinate; WY45233 Succinate; WY-45233 Succinate. CAS No. 386750-22-7. Pack Sizes: 5 g. Product ID: B2693-067733. Molecular formula: C20H33NO7. Mole weight: 399.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Erlotinib O-Desmethyl Metabolite Isomer (M14) HCl | OSI-420 (CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells. Uses: For research used only. Group: Pharmaceutical. Alternative Names: OSI420; OSI-420; OSI 420; CP473420; CP-473420; CP 473420; Desmethyl Erlotinib. CAS No. 183320-51-6. Pack Sizes: 10 mg. Product ID: B0084-286627. Molecular formula: C21H22ClN3O4. Mole weight: 415.874. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Azelastine | N-Desmethyl Azelastine is the main metabolite of Azelastine. Azelastine is a potent, selective and second-generation histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor. Group: Pharmaceutical. Alternative Names: Desmethylazelastine; 4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1H-azepin-4-yl)-1(2H)-phthalazinone; Azelastine Hydrochloride Impurity. CAS No. 47491-38-3. Pack Sizes: 50 mg. Product ID: B2694-467139. Molecular formula: C21H22ClN3O. Mole weight: 367.88. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl citalopram-[d4] oxalate | N-Desmethyl citalopram-[d4] oxalate is a deuterated compound of N-Desmethyl citalopram Oxalate, which is an impurity of Citalopram. Group: Pharmaceutical. CAS No. 2747915-54-2. Pack Sizes: 10 mg. Product ID: BLP-014896. Molecular formula: C21H17D4FN2O5. Mole weight: 404.42. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Citalopram Oxalate | An impurity of Citalopram, an antidepressant of the selective serotonin reuptake inhibitor class. Group: Pharmaceutical. Alternative Names: N-Desmethyl Citalopram Oxalate salt; Desmethylcitalopram oxalate; 1-(4-fluorophenyl)-1-[3-(methylamino)propyl]-1,3-dihydro-2-benzofuran-5-carbonitrile oxalate. CAS No. 62498-68-4. Pack Sizes: 10 mg. Product ID: B1370-105942. Molecular formula: C21H21FN2O5. Mole weight: 400.4. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Clarithromycin | A metabolite of the macrolide antibiotic, Clarithromycin. Group: Pharmaceutical. Alternative Names: N-Demethyl-6-O-methylerythromycin; 3''-N-Demethylclarithromycin; N-Demethylclarithromycin; Clarithromycin EP Impurity D. CAS No. 101666-68-6. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04429. Molecular formula: C37H67NO13. Mole weight: 733.93. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Dofetilide | N-Desmethyldofetilide is a derivative of Dofetilide. Dofetilide is a selective potassium channel ((hERG)) blocker, used as a Class III antiarrhythmic drug. Group: Pharmaceutical. Alternative Names: Dofetilide USP Related Compound A; Dofetilide Impurity 1; Methanesulfonamide, N-[4-[2-[[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]-; N-(4-(2-((4-(Methylsulfonamido)phenethyl)amino)ethoxy)phenyl)methanesulfonamide. CAS No. 176447-94-2. Pack Sizes: 50 mg. Product ID: B1370-165790. Molecular formula: C18H25N3O5S2. Mole weight: 427.54. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Edoxaban | N-Desmethyl Edoxaban is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Group: Pharmaceutical. Alternative Names: Demethyledoxaban impurity; N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide. CAS No. 778571-11-2. Pack Sizes: 10 mg. Product ID: B1370-426139. Molecular formula: C23H28ClN7O4S. Mole weight: 534.03. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Edoxaban Hydrochloride | N-Desmethyl Edoxaban Hydrochloride is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Group: Pharmaceutical. Alternative Names: Edoxaban M6; N1-(5-Chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide Hydrochloride. CAS No. 480449-52-3. Pack Sizes: 10 mg. Product ID: B1370-099170. Molecular formula: C23H29Cl2N7O4S. Mole weight: 570.49. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Enzalutamide | N-desmethyl Enzalutamide is a major metabolite of Enzalutamide. Enzalutamide is an androgen-receptor (AR) antagonist (IC50 = 36 nM) in LNCaP cells that inhibits the transcriptional activity of a mutant AR protein. Enzalutamide resists against induction of prostate-specific antigen (PSA) and transmembrane serine protease 2 (TMPRSS2). N-desmethyl Enzalutamide can be used for the treatment of disorders involving androgen, estrogen and progesterone receptors. Uses: The treatment of disorders involving androgen, estrogen and progesterone receptors. Group: Pharmaceutical. Alternative Names: N-desmethylenzalutamide; 1242137-16-1; 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzamide; 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluorobenzamide; Enzalutamide metabolite. CAS No. 1242137-16-1. Pack Sizes: 20 mg. Product ID: B0084-474425. Molecular formula: C20H14F4N4O2S. Mole weight: 450.412. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Imatinib | A metabolite of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Group: Pharmaceutical. Alternative Names: N-[4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)-benzamide; N-Desmethyl Gleevec. CAS No. 404844-02-6. Pack Sizes: 10 mg. Product ID: B2694-473156. Molecular formula: C28H29N7O. Mole weight: 479.59. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Imatinib-[d8] | N-Desmethyl Imatinib-[d8] is a deuterated metabolite of gleevec, a tyrosine kinase inhibitor specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). Group: Pharmaceutical. Alternative Names: N-Desmethyl Imatinib D8; N-Desmethyl Gleevec-d8. CAS No. 1185103-28-9. Pack Sizes: 5 mg. Product ID: BLP-009648. Molecular formula: C28H21D8N7O. Mole weight: 487.64. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyltamoxifen | N-Desmethyltamoxifen is a metabolite of tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Group: Pharmaceutical. Alternative Names: Desmethyltamoxifen; Tamoxifen EP Impurity F; 2-[4-[(Z)-1,2-Diphenylbut-1-en-1-yl]phenoxy]-N-methylethan-1-amine; N-Demethyltamoxifen; Demethyltamoxifen; 2-[4-[(1Z)-1,2-Diphenyl-1-butenyl]phenoxy]-N-methylethanamine; (2-(4-((1Z)-1,2-Diphenylbut-1-en-1-yl)phenoxy)ethyl)(methyl)amine; 2-[4-[(1Z)-1,2-Diphenyl-1-buten-1-yl]phenoxy]-N-methylethanamine; (Z)-2-[p-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethylamine; Tamoxifen Citrate EP Impurity F; Tamoxifen Citrate Impurity F; Tamoxifen Impurity F. CAS No. 31750-48-8. Pack Sizes: 1 g. Product ID: B1370-107540. Molecular formula: C25H27NO. Mole weight: 357.49. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Tamoxifen-[d5] | An isotope labelled metabolite of Tamoxifen. Tamoxifen is a medication that is used to treat breast cancer. Group: Pharmaceutical. Alternative Names: (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethanamine-d5. CAS No. 164365-16-6. Pack Sizes: 5 mg. Product ID: BLP-013914. Molecular formula: C25H22D5NO. Mole weight: 362.52. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Tamoxifen HCl | One of the impurities of Tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Group: Pharmaceutical. Alternative Names: (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethanamine Hydrochloride; N-Demethyltamoxifen Hydrochloride; N-Desmethyl Tamoxifen Hydrochloride. CAS No. 15917-65-4. Pack Sizes: 100 mg. Product ID: B1370-260466. Molecular formula: C25H27NO.HCl. Mole weight: 393.96. Custom synthesis is available. Send your inquiries for more information. Categories: N-DesmethylTamoxifen HCl. | London |
| N-Desmethyl Ulipristal Acetate | N-Desmethyl Ulipristal Acetate is a metabolite of Ulipristal. Ulipristal is a selective progesterone receptor modulator (SPRM) used for emergency contraception and uterine fibroid. Group: Pharmaceutical. Alternative Names: (11β)-17-(Acetyloxy)-11-[4-(methylamino)phenyl]-19-norpregna-4,9-diene-3,20-dione; CDB 3877; N-Monodemethyl CDB 2914. CAS No. 159681-66-0. Pack Sizes: 100 mg. Product ID: B1917-452616. Molecular formula: C29H35NO4. Mole weight: 461.61. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Vandetanib | N-Desmethyl Vandetanib is a metabolite of Vandetanib. Vandetanib is an antitumor drug used for the treatment of medullary thyroid cancer. Vandetanib effects through inhibiting vascular endothelial growth factor receptor-2 (VEGFR), epidermal growth factor receptor (EGFR) and the RET-tyrosine kinase activity. Group: Pharmaceutical. Alternative Names: N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(4-piperidinylmethoxy)-4-quinazolinamine; 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(piperidin-4-yl)methoxy]quinazoline. CAS No. 338992-12-4. Pack Sizes: 5 mg. Product ID: B1926-260255. Molecular formula: C21H22BrFN4O2. Mole weight: 461.34. Custom synthesis is available. Send your inquiries for more information. | London |
| O-Desmethyl Apixaban | A metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Group: Pharmaceutical. Alternative Names: 4-Demethoxy-4-hydroxy apixaban. CAS No. 503612-76-8. Pack Sizes: 100 mg. Product ID: B2694-466672. Molecular formula: C24H23N5O4. Mole weight: 445.48. Custom synthesis is available. Send your inquiries for more information. | London |
| O-Desmethyl Venlafaxine Cyclic Impurity | O-Desmethyl Venlafaxine Cyclic Impurity is a cyclic impurity of O-Desmethylvenlafaxine. Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. Group: Pharmaceutical. Alternative Names: 5-(4-Hydroxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane; 4-(3-Methyl-1-oxa-3-azaspiro[5.5]undecanyl)phenol. CAS No. 1346601-55-5. Pack Sizes: 10 mg. Product ID: B2694-485086. Molecular formula: C16H23NO2. Mole weight: 261.37. Custom synthesis is available. Send your inquiries for more information. | London |
| rac-N-Desmethyl Bedaquiline | rac-N-Desmethyl Bedaquiline is an intermediate used in th synthesis of Bedaquiline, a medication approved for the treatment of active tuberculosis. Group: Pharmaceutical. Alternative Names: N-Monodesmethyl bedaquiline. CAS No. 654654-76-9. Pack Sizes: 1 g. Product ID: B2692-007095. Molecular formula: C31H29BrN2O2. Mole weight: 541.5. Custom synthesis is available. Send your inquiries for more information. | London |
| 17-DMAG hydrochloride | 17-DMAG hydrochloride (Alvespimycin hydrochloride) is the hydrochloride salt of alvespimycin, an analogue of the antineoplastic benzoquinone antibiotic geldanamycin. Alvespimycin binds to Hsp90, a chaperone protein that aids in the assembly, maturation and folding of proteins. Subsequently, the function of Hsp90 is inhibited, leading to the degradation and depletion of its client proteins such as kinases and transcription factors involved with cell cycle regulation and signal transduction. Group: Pharmaceutical. Alternative Names: 17-DMAG HCl; Alvespimycin HCl; 17-Dimethylaminoethylamino-17-demethoxygeldanamycin Hydrochloride; 17-N-(2-Dimethylaminoethylamino)-17-demethoxy Geldanamycin Hydrochloride; 17-Demethoxy-17-[[2-(dimethylamino)ethyl]amino]geldanamycin Hydrochloride; 17-[2-(Dimethylamino)ethylamino]-17-desmethylgeldanamycin Hydrochloride; Alvespimycin Hydrochloride; DMAG Hydrochloride; NSC 707545 Hydrochloride; 17-DMAG Hydrochloride. CAS No. 467214-21-7. Pack Sizes: 100 mg. Product ID: BBF-05796. Molecular formula: C32H48N4O8.HCl. Mole weight: 653.21. Custom synthesis is available. Send your inquiries for more information. | London |
| ADT-OH | ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. ADT is a putative neuroprotectant and antioxidant that increases glutathione levels in cultured astroglial cells. ADT-OH was shown to reduce tPA-enhanced Akt activation and VEGF expression in brain microvascular endothelial cells. Group: Pharmaceutical. Alternative Names: 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione; Desmethylanethol trithione; 3H-1,2-Dithiole-3-thione, 5-(4-hydroxyphenyl)-. CAS No. 18274-81-2. Pack Sizes: 50 mg. Product ID: B0084-284826. Molecular formula: C9H6OS3. Mole weight: 226.326. Custom synthesis is available. Send your inquiries for more information. | London |
| α,α,α',5-Tetramethyl-1, 3- benzenediacetonitril e | α,α,α',5-Tetramethyl-1, 3- benzenediacetonitril e is an intermediate in the synthesis of α-Desmethyl Anastrozole. Group: Pharmaceutical. Alternative Names: alpha1,alpha3,alpha3,5-Tetramethyl-1,3-benzenediacetonitrile. CAS No. 120512-38-1. Pack Sizes: 100 mg. Product ID: BB076990. Molecular formula: C14H16N2. Mole weight: 212.29. Custom synthesis is available. Send your inquiries for more information. | London |
| Azithromycin EP Impurity E | Azithromycin EP Impurity E is one of several different impurities found in the macrolide antibiotic, azithromycin. It can be used as a reference standard for azithromycin impurity tracing. Group: Pharmaceutical. Alternative Names: 3'-(N,N-Didemethyl)azithromycin; aminoazithromycin; N',N'-Di(desmethyl) azithromycin; 3'-N,N-Di(desmethyl) azithromycin. CAS No. 612069-27-9. Pack Sizes: 50 mg. Product ID: B0051-467180. Molecular formula: C36H68N2O12. Mole weight: 720.95. Custom synthesis is available. Send your inquiries for more information. | London |
| Azithromycin EP Impurity I | Azithromycin EP Impurity I is an impurity of azithromycin, a macrolide antibiotic used for bacterial infections. Group: Pharmaceutical. Alternative Names: CP-64434; Azithromycin Impurity I; N'-Desmethyl Azithromycin; 3'-N-Desmethylazithromycin; N-Demethylazithromycin. CAS No. 172617-84-4. Pack Sizes: 50 mg. Product ID: B0051-467173. Molecular formula: C37H70N2O12. Mole weight: 734.98. Custom synthesis is available. Send your inquiries for more information. | London |
| Azithromycin EP Impurity M | Azithromycin EP Impurity M is a degradation product of Azithromycin. Group: Pharmaceutical. Alternative Names: 3'-(N,N-Didemethyl)-3'-N-formylazithromycin; 3'-N,N-Di(desmethyl)-3'-N-formyl Azithromycin. CAS No. 765927-71-7. Pack Sizes: 2.5 mg. Product ID: B0051-467182. Molecular formula: C37H68N2O13. Mole weight: 748.96. Custom synthesis is available. Send your inquiries for more information. | London |
| Celecoxib EP Impurity A | A meta positional isomer of Celecoxib with selective inhibitory activity against human cyclooxygenase-2. Group: Pharmaceutical. Alternative Names: Celecoxib USP Related Compound A; Celecoxib 3-Methyl Analog; 4-Desmethyl-3-methyl Celecoxib; 4-[5-(3-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide. CAS No. 170570-01-1. Pack Sizes: 100 mg. Product ID: B2694-468619. Molecular formula: C17H14F3N3O2S. Mole weight: 381.38. Custom synthesis is available. Send your inquiries for more information. | London |
| Chlorphenamine EP Impurity C | An impurity of Chlorpheniramine, which inhibits the proliferation of MCF-7, MDA-MB 231, and Ehrlich cells in a dose-response manner, and significantly reduces the ornithine decarboxylase mRNA translation by 50%-70% at the 250 μM. Group: Pharmaceutical. Alternative Names: N-Desmethylchlorpheniramine; monodesmethylchlorpheniramine; N-Methyl-3-(4-chlorophenyl)-3-(2-pyridyl)propan-1-amine; γ-(4-Chlorophenyl)-N-methyl-2-pyridinepropanamine. CAS No. 20619-12-9. Pack Sizes: 25 mg. Product ID: B1370-421154. Molecular formula: C15H17ClN2. Mole weight: 260.76. Custom synthesis is available. Send your inquiries for more information. | London |
| Chlorphenamine Impurity C Maleate | A metabolite of Chlorpheniramine, an antihistamine that works by blocking the action of histamine. Group: Pharmaceutical. Alternative Names: N-Desmethyl-Chlorpheniramine; 2-[p-Chloro-α-[2-(methylamino)ethyl]benzyl]pyridine Maleate. CAS No. 22630-25-7. Pack Sizes: 5 mg. Product ID: B2694-468812. Molecular formula: C15H17ClN2.C4H4O4. Mole weight: 376.8. Custom synthesis is available. Send your inquiries for more information. | London |
| Demethylcephalotaxinone | Demethylcephalotaxinone is a natural alkaloid compound found in several plants. Group: Pharmaceutical. Alternative Names: Desmethylcephalotaxinone;(S)-1-hydroxy-5,6,8,9-tetrahydro-4H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]cyclopenta[b]pyrrolo[1,2-a]azepin-2(3H)-one. CAS No. 51020-45-2. Pack Sizes: 1 mg. Product ID: NP0287. Molecular formula: C17H17NO4. Mole weight: 299.32. Custom synthesis is available. Send your inquiries for more information. | London |
| Desvenlafaxine fumarate | An impurity of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Group: Pharmaceutical. Alternative Names: O-Desmethylvenlafaxine fumarate; 4-(2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol fumarate. CAS No. 93414-04-1. Pack Sizes: 25 mg. Product ID: B1370-290693. Molecular formula: C20H29NO6. Mole weight: 379.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Erythromycin EP Impurity B | A metabolite of Erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. Group: Pharmaceutical. Alternative Names: N-Demethylerythromycin A; N-Desmethyl Erythromycin A; Des-N-methylerythromycin; Demethylerythromycin; USP Erythromycin Related Compound N; 3'-Demethylerythromyon; 11,13-hexamethyl-oxacyclotetradecane-2,10-dione. CAS No. 992-62-1. Pack Sizes: 25 mg. Product ID: BBF-04556. Molecular formula: C36H65NO13. Mole weight: 719.9. Custom synthesis is available. Send your inquiries for more information. | London |
| (E/Z)-Endoxifen | One of the impurities of Tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Group: Pharmaceutical. Alternative Names: 4-Hydroxy-N-Desmethyl Tamoxifen; N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture); 4-[1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol. CAS No. 110025-28-0. Pack Sizes: 10 mg. Product ID: B2694-257357. Molecular formula: C25H27NO2. Mole weight: 373.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Gardenin B | Gardenin B is a natural flavonoid compound found in several plants. Group: Pharmaceutical. Alternative Names: 4',6,7,8-Tetramethoxy-5-hydroxyflavone; 5-Hydroxy-4',6,7,8-tetramethoxyflavone; 5-O-Desmethyltangeretin; 5-DesMethyltangeretin; 5-O-DeMethyltangeretin; Demethyltangeretin. CAS No. 2798-20-1. Pack Sizes: 5 mg. Product ID: NP1961. Molecular formula: C19H18O7. Mole weight: 358.342. Custom synthesis is available. Send your inquiries for more information. | London |
| Lasofoxifene | Lasofoxifene (INN) (proposed tradename Fablyn) is a non-steroidal selective estrogen receptor modulator (SERM) which is under development by Pfizer for the prevention and treatment of osteoporosis and for the treatment of vaginal atrophy, and the result of an exclusive research collaboration with Ligand Pharmaceuticals (LGND). In September 2005, Pfizer received a non-approvable letter from the U.S. Food and Drug Administration regarding lasofoxifene ( Oporia), a selective estrogen receptor modulator for the prevention of osteoporosis. Lasofoxifene was approved in the EU under the Fablyn by the EMEA in March 2009. Lasofoxifene is a desmethyl dihydro analog of nafoxidine. Group: Pharmaceutical. Alternative Names: CP 336156; CP336156; CP-336156; CP 336,156; CP336,156; CP-33,6156; Fably; Oporia. CAS No. 180916-16-9. Pack Sizes: 100 mg. Product ID: B2693-465309. Molecular formula: C28H31NO2. Mole weight: 413.561. Custom synthesis is available. Send your inquiries for more information. | London |
| Levofloxacin Related Compound A | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Group: Pharmaceutical. Alternative Names: N-Desmethyl Levofloxacin ; (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid. CAS No. 117707-40-1. Pack Sizes: 30 mg. Product ID: B0185-241663. Molecular formula: C17H18FN3O4. Mole weight: 347.35. Custom synthesis is available. Send your inquiries for more information. | London |
| Metoprolol Impurity A | C-Desmethyl Metoprolol is a new byproduct detected in Metoprolol tartrate. It is a Metoprolol impurity. Group: Pharmaceutical. Alternative Names: C-Desmethyl Metoprolol; 1-(Ethylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol; H 173/09; USP Metoprolol Related Compound A. CAS No. 109632-08-8. Pack Sizes: 50 mg. Product ID: B2694-260444. Molecular formula: C14H23NO3. Mole weight: 253.34. Custom synthesis is available. Send your inquiries for more information. | London |
| Metoprolol Impurity H | O-Desmethyl Metoprolol is a metabolite of Metoprolol. Group: Pharmaceutical. Alternative Names: O-Desmethyl Metoprolol; 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzeneethanol; (+/-)-4-[2-Hydroxy-3-(isopropylamino)propoxy]phenylethyl Alcohol; (+/-)-O-Demethylmetoprolol; H 105/22; SL 80-0088. CAS No. 62572-94-5. Pack Sizes: 100 mg. Product ID: B0151-260445. Molecular formula: C14H23NO3. Mole weight: 253.34. Custom synthesis is available. Send your inquiries for more information. | London |
| Mycophenolate Mofetil EP Impurity A | An impurity of Mycophenolate Mofetil which is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively. Group: Pharmaceutical. Alternative Names: O-Desmethyl Mycophenolate Mofetil; 2-(4-Morpholinyl)ethyl (4E)-6-(1,3-dihydro-4,6-dihydroxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoate; Mycophenolate Mofetil Related Compound A (USP). CAS No. 1322681-36-6. Pack Sizes: 50 mg. Product ID: B1370-237823. Molecular formula: C22H29NO7. Mole weight: 419.47. Custom synthesis is available. Send your inquiries for more information. | London |
| Norfloxacin | Norfloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase. It is a synthetic chemotherapeutic antibacterial agent occasionally used to treat common as well as complicated urinary tract infections. It is approved for use in children older than one year of age. However, it is associated with a number of rare serious adverse reactions as well as spontaneous tendon ruptures and irreversible peripheral neuropathy. Uses: Anti-bacterial agents; enzyme inhibitors; nucleic acid synthesis inhibitors. Group: Pharmaceutical. Alternative Names: Noroxin; Chibroxin; AM-715; MK-366; AM 715; MK 366; AM715; MK366; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid; Baccidal; Barazan; Chibroxine; N-Desmethylpefloxacin; Sebercim; Zoroxin. CAS No. 70458-96-7. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04625. Molecular formula: C16H18FN3O3. Mole weight: 319.33. Custom synthesis is available. Send your inquiries for more information. | London |
| Omeprazole 4'-O-Demethyl Impurity | Omeprazole 4'-O-Demethyl Impurity is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Group: Pharmaceutical. Alternative Names: 4-Hydroxy Omeprazole; Desmethoxy Keto Esomeprazole; 2-[[(5-Methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-3,5-dimethyl-4-pyridinol; 4'-O-Desmethylomeprazole; Omeprazole 4-Desmethyl Impurity. CAS No. 301669-82-9. Pack Sizes: 10 mg. Product ID: B1370-016494. Molecular formula: C16H17N3O3S. Mole weight: 331.39. Custom synthesis is available. Send your inquiries for more information. | London |
| Pseudopalmatine | Pseudopalmatine isolated from the herbs of Tinospora sinensis. Uses: Antiplasmodial activity; anti-ache ic50 values. Group: Pharmaceutical. Alternative Names: 5,6-Dihydro-2,3,10,11-tetramethoxydibenzo[a,g]quinolizinium;5,6-Dihydro-8-desmethylcoralyne; 2,3,10,11-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium. CAS No. 19716-66-6. Pack Sizes: 1 mg. Product ID: NP0344. Molecular formula: C21H22NO4. Mole weight: 352.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Rifaximin EP Impurity H | Rifaximin EP Impurity H is an intermediate of Rifaximin. Rifaximin is a semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. It also acts as a pregnane X receptor (PXR) agonist. It is approved for the treatment of traveler's diarrhea, irritable bowel syndrome, and hepatic encephalopathy. Group: Pharmaceutical. Alternative Names: 16-Desmethyl-16-(hydroxymethyl)rifaximin; (2S,16Z,18E,20S,21S,22R,23R,24R,25S,26R,27S,28E)-25-(Acetyloxy)-5,6,21,23-tetrahydroxy-16-(hydroxymethyl)-27-methoxy-2,4,11,20,22,24,26-heptamethyl-2,7-(epoxypentadeca(1,11,13)trienimino)benzofuro(4,5-E)pyrido(1,2-a)benzimidazole-1,15(2H)-dione. CAS No. 1210022-90-4. Pack Sizes: 1 mg. Product ID: B1370-479077. Molecular formula: C43H51N3O12. Mole weight: 801.88. Custom synthesis is available. Send your inquiries for more information. | London |
| Rivastigmine EP Impurity B | An impurity of Rivastigmine. Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Group: Pharmaceutical. Alternative Names: (R,S)-3-[1-(Dimethylamino)ethyl]phenyl dimethylcarbamate; RivastigMine USP RC B; Desmethyl Rivastigmine; N-Desethyl N-Methyl rac-Rivastigmine; N,N-Dimethylcarbamic acid 3-[(RS)-1-(dimethyl amino) ethyl]phenyl ester. CAS No. 25081-93-0. Pack Sizes: 10 mg. Product ID: B1370-264654. Molecular formula: C13H20N2O2. Mole weight: 236.32. Custom synthesis is available. Send your inquiries for more information. | London |
| (R)-(-)-Nirvanol | (R)-(-)-Nirvanol is a Mephentoin metabolite with anticonvulsant and hypnotic properties. Group: Pharmaceutical. Alternative Names: (R)-5-Ethyl-5-phenylimidazolidine-2,4-dione; R-(-)-N-Desmethyl Mephenytoin; (-)-5-Ethyl-5-phenylhydantoin. CAS No. 65567-32-0. Pack Sizes: 1 g. Product ID: B2693-195330. Molecular formula: C11H12N2O2. Mole weight: 204.23. Custom synthesis is available. Send your inquiries for more information. | London |
| Rosuvastatin EP Impurity A Calcium Salt | Rosuvastatin EP Impurity A Calcium Salt is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Group: Pharmaceutical. Alternative Names: 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-2-[[(2-hydroxy-2-methylpropyl)sulfonyl]methylamino]-6-(1-methylethyl)-5-pyrimidinyl]-3,5-dihydroxy-, calcium salt (2:1), (3R,5S,6E)-; (3R,5S,E)-7-(4-(4-Fluorophenyl)-2-((2-hydroxy-N,2-dimethylpropyl)sulfonamido)-6-isopropylpyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate Calcium Salt; S-Desmethyl-S-(2-hydroxy-2-methylpropyl) Rosuvastatin Calcium Salt; (3R,5S,6E)-7-[2-(2,N-Dimethyl-2-hydroxypropane-1-sulfonamido)-4-(4-fluorophenyl)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid calcium salt; Calcium (3R,5S,E)-7-{4-(4-fluorophenyl)-2-[(2-hydroxy-N,2-dimethylpropyl)sulfonamide]-6-isopropylpyrimidin-5-yl}-3,5-dihydroxyhept-6-enoate salt (1:2); USP Rosuvastatin Related Compound A; Rosuvastatin Related Compound A; Rosuvastatin USP Related Compound A. CAS No. 1714147-47-3. Pack Sizes: 5 mg. Product ID: B2694-010332. Molecular formula: C25H33FN3O7S.1/2Ca. Mole weight: 558.65. Custom synthesis is available. Send your inquiries for more information. | London |
| Tacrolimus EP Impurity C | Tacrolimus EP Impurity C is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Group: Pharmaceutical. Alternative Names: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,12,18-trimethyl-8-(prop-2-en-1-yl)-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone; 10-Desmethyl tacrolimus; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosin. Pack Sizes: 1mg;1g;10g. Product ID: BBF-05742. Molecular formula: C43H67NO12. Mole weight: 789.99. Custom synthesis is available. Send your inquiries for more information. | London |
| Thiamine EP Impurity B | An impurity of Thiamine which is an important vitamin in carbohydrate (sugar and starch) metabolism, maintenance of normal growth, and transmission of nerve impulses. Group: Pharmaceutical. Alternative Names: Desmethylthiamine; 2-Northiamin; Desmethyl Thiamine; 3-((4-Amino-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium. CAS No. 7771-57-5. Pack Sizes: 25 mg. Product ID: B1370-455514. Molecular formula: C11H15N4OS. Mole weight: 251.33. Custom synthesis is available. Send your inquiries for more information. | London |
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