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It is an antiviral agent. Group: Pharmaceutical. CAS No. 87418-35-7. Pack Sizes: 50 mg. Product ID: B2706-340299. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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2',3'-Dideoxy-3'-fluorouridine
2',3'-Dideoxy-3'-fluorouridine is a reactant used in the synthesis of 5'-trityl nucleosides to inhibit Plasmodium falciparum dUTPase. It exhibits anti-retrovirus activity. Group: Pharmaceutical. CAS No. 41107-56-6. Pack Sizes: 100 mg. Product ID: B2706-316809. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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2'-Deoxy-2'-fluoro-5-iodouridine
It is an antiviral drug and nucleoside analogue with anti-hepatitis B activity. Group: Pharmaceutical. CAS No. 55612-21-0. Pack Sizes: 100 mg. Product ID: B1370-261441. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine
It is the impurity C of Clofarabine and is also an anticancer agent. Group: Pharmaceutical. CAS No. 103884-98-6. Pack Sizes: 250 mg. Product ID: B2706-081123. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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2'-Deoxy-4'-ethynyl-2-fluoroadenosine
Islatravir (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. Uses: Enzyme inhibitors. Group: Pharmaceutical. CAS No. 865363-93-5. Pack Sizes: 10 mg. Product ID: B2705-038148. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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2'-Deoxy-5-fluorocytidine
1g Pack Size. Group: Biochemicals, Building Blocks, Fluorinated Products. Formula: C9H12FN3O4. CAS No. 66335-38-4. Prepack ID : 79755577-1g. Molecular Weight : 245.21.
(2'R)-2'-deoxy-2'-fluoro-2'-C-methyluridine
PSI-6206 is a selective HCV RNA polymerase inhibitor. It is the unphosphorylated parent compound of triphosphate analog PSI-7409, which is a potent inhibitor of the HCV NS5B RNA dependent RNA polymerase. Group: Pharmaceutical. CAS No. 863329-66-2. Pack Sizes: 5 g. Product ID: B2693-459960. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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3'-Deoxy-3'-fluorocytidine
3'-Deoxy-3'-fluorocytidine is a purine nucleoside analogue. It is an antiviral agent. Group: Pharmaceutical. CAS No. 123402-20-0. Pack Sizes: 5 mg. Product ID: B1370-279821. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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3'-Deoxy-3'-fluorouridine
3'-Deoxy-3'-fluorouridine, a compound of utmost significance in the biomedical industry, assumes a pivotal position in the advancement of antiviral pharmaceuticals targeting RNA virus-associated ailments. This exceptional product showcases its robust antiviral efficacy against a multitude of viruses. Through the powerful mechanism of inhibiting viral replication, 3'-Deoxy-3'-fluorouridine emerges as a propitious contender in the ongoing battle against these formidable infectious maladies. Group: Pharmaceutical. CAS No. 57944-13-5. Pack Sizes: 5 mg. Product ID: B2706-279822. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine is a highly complex and perplexing compound, playing a pivotal role in combatting viruses. Notably, it showcases exceptional selectivity and efficacy against viral replication and tumor proliferation, thereby emerging as an indispensable asset in the development of antiviral medicines and anticancer researchs. Group: Pharmaceutical. CAS No. 1445379-59-8. Pack Sizes: 1 g. Product ID: B1370-072091. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
5-[3-(Trifluoroacetamido)-E-1-propenyl]-2'-deoxyuridine is a potent antiviral agent utilized in the treatment of viral infections caused by herpes simplex viruses (HSV-1, HSV-2), varicella-zoster virus (VZV), and Epstein-Barr virus (EBV). This compound inhibits viral DNA replication, reducing viral propagation and promoting host recovery. Its mechanism of action involves the incorporation into viral DNA, leading to chain termination. Group: Pharmaceutical. CAS No. 115794-55-3. Pack Sizes: 1 g. Product ID: B0001-331230. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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5-Fluoro-2'-deoxyuridine
1g Pack Size. Group: Biochemicals, Building Blocks. Formula: C9H11FN2O5. CAS No. 50-91-9. Prepack ID : 27134875-1g. Molecular Weight : 246.19.
5-Fluoro-2'-deoxyuridine-5'-triphosphate (triethylammonium salt form)
An impurity of UTP. UTP is a pyrimidine nucleoside triphosphate as a substrate in the biosynthesis of RNA. Group: Pharmaceutical. CAS No. 1621676-99-0. Pack Sizes: 1 mg. Product ID: B1331-007255. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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5-Fluoro-5'-deoxyuridine
5g Pack Size. Group: Biochemicals. Formula: C9H11FN2O5. CAS No. 3094-9-5. Prepack ID : 10130089-5g. Molecular Weight : 246.2.
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite (CAS# 146954-75-8) is a useful research chemical. Group: Pharmaceutical. CAS No. 146954-75-8. Pack Sizes: 5 g. Product ID: B2706-084339. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-2'-fluoro-N2-isobutyryl-2'-Deoxy-guanosine 3'-CE phosphoramidite is a novel nucleoside analog for the incorporation of 2-fluoro-modified ribose-G nucleobases within oligonucleotides. Group: Pharmaceutical. CAS No. 144089-97-4. Pack Sizes: 5 g. Product ID: B2706-291975. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-5-Fluoro-2'-deoxyuridine-3'-CE Phosphoramidite is a highly potent reagent for the synthesis of 5-fluorouracil (5-FU) containing oligonucleotides, with potential applications in the treatment of cancer. By boosting the selectivity and efficacy of 5-FU, a well-established chemotherapy drug for different forms of cancer, this compound constitutes a promising avenue to enhance the therapeutic options available to patients. Group: Pharmaceutical. CAS No. 142246-63-7. Pack Sizes: 250 mg. Product ID: B2706-049657. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-N4-Acetyl-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite is a phosphoramidite compound used to introduce 2-fluoro-modified nucleotides into oligonucleotides. Group: Pharmaceutical. CAS No. 159414-99-0. Pack Sizes: 10 g. Product ID: B2706-395301. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
As an analog of the antitumour and antiviral naturally occurring nucleoside 9-(β-D-arabinofuranosyl)adenine (ara-A), 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine inhibited the growth of T. vaginalis with an IC50 of 0.09μM. Uses: Anti-neoplastic; inhibits the growth of t. vaginalis with an ic50 of 0.09μm. Group: Pharmaceutical. CAS No. 20227-41-2. Pack Sizes: 200 mg. Product ID: B0084-086977. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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N2-iso-Butyroyl-3'-deoxy-3'-fluoroguanosine
N2-iso-Butyroyl-3'-deoxy-3'-fluoroguanosine, a crucial compound in the field of biomedicine, showcases its potency as an effective antiviral agent targeted at treating viral infections resulting from the influenza virus. By virtue of its distinct chemical characteristics, it displays remarkable capability in hindering viral replication and alleviating the severity of influenza-related symptoms. Group: Pharmaceutical. CAS No. 2080404-20-0. Pack Sizes: 5 mg. Product ID: B1370-125991. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-deoxy-3'-fluoroguanosine, a biomedical compound, demonstrates its effectiveness in targeting and treating specific diseases. Its therapeutic potential and precise mechanism of action can be explored through the referenced websites, providing comprehensive information concerning drug interactions and its efficacy in addressing various medical conditions. Group: Pharmaceutical. CAS No. 2080404-19-7. Pack Sizes: 10 mg. Product ID: B1370-127007. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite is an indispensable compound within the biomedical domain with widespread application as a phosphoramidite constituent during oligonucleotide synthesis, primarily in the research of antisense therapy and gene silencing. Group: Pharmaceutical. CAS No. 142808-44-4. Pack Sizes: 100 mg. Product ID: B2706-337702. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite can be used to incorporate 2-fluoro modified nucleotides into oligonucleotides, improving metabolic stability. Group: Pharmaceutical. CAS No. 136834-22-5. Pack Sizes: 10 g. Product ID: B2706-291972. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE-phosphoramidite is an antiviral agent that inhibits the replication of DNA. Group: Pharmaceutical. CAS No. 329187-86-2. Pack Sizes: 1 g. Product ID: B2706-291985. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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5-(Hydroxymethyl)-2'-deoxyuridine
5-(Hydroxymethyl)-2'-deoxyuridine is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 μM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 μM). 5-(Hydroxymethyl)-2'-deoxyuridine acts synergistically with 5-fluorouracil (5-FU) against HT-29, HCT116, PANC-1, and EKVX cancer cells with no effect on WI38 embryonic lung fibroblasts. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 5116-24-5. Pack Sizes: 1 g. Product ID: B1370-120698. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Gemcitabine elaidate
Gemcitabine elaidate (also known as CO-101; CP-4126) is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. Due to its lipophilicity, gemcitabine 5'-elaidic acid ester exhibits an increased cellular uptake and accumulation, resulting in an increased conversion to active metabolites, compared to gemcitabine. In addition, this formulation of gemcitabine may be less susceptible to deamination and deactivation by deoxycytidine deaminase. Group: Pharmaceutical. CAS No. 210829-30-4. Pack Sizes: 25 mg. Product ID: B2706-225221. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Sofosbuvir
Sofosbuvir is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Uses: Antiviral agents. Group: Pharmaceutical. CAS No. 1190307-88-0. Pack Sizes: 2.5 g. Product ID: B0084-457411. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
TAS-102
TAS-102 is a combination drug composed of the cytotoxic pyrimidine analog Trifluridine (5-trifluoro-2'-deoxythymidine or TFT) and a thymidine phosphorylase inhibitor (TPI) tipiracil hydrochloride, in a molar ratio of 1.0:0.5 (TFT:TPI). TAS-102 is used as a third- or fourth-line treatment of metastatic colorectal cancer. Group: Pharmaceutical. CAS No. 733030-01-8. Pack Sizes: 50 mg. Product ID: B0046-462799. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
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