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| Product | Description | |
|---|---|---|
| 2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine | A metabolite of Capecitabine. Group: Pharmaceutical. Alternative Names: 5'-Deoxy-5-fluoro-cytidine 2',3'-Diacetate; 2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine; 5'-Deoxy-2',3'-di-O-acetyl-5-fluorocytidine; 2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-D-cytidine; 1-(2,3-Di-O-acetyl-5-deoxy-beta-D-ribofuranosyl)-4-amino-5-fluoropyrimidin-2(1H)-one; (2R,3R,4R,5R)-2-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-5-methyl-tetrahydrofuran-3,4-diyl diacetate; Capecitabine Diacetyl Amino Impurity (USP). CAS No. 161599-46-8. Pack Sizes: 1mg;1g;10g. Product ID: NP3683. Molecular formula: C13H16FN3O6. Mole weight: 329.29. Custom synthesis is available. Send your inquiries for more information. |  London |
| 2'-Deoxy-2'-fluoro-5-iodouridine | It is an antiviral drug and nucleoside analogue with anti-hepatitis B activity. Group: Pharmaceutical. Alternative Names: 1-(2'-Deoxy-2'-fluoro-beta-D-ribofuranosyl)-5-iodouracil; 2'-epi-Fialuridine; FIRU; 5-Iodo-1-(2-fluoro-2-deoxy-beta-D-ribofuranosyl)uracil; 1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione. CAS No. 55612-21-0. Pack Sizes: 100 mg. Product ID: B1370-261441. Molecular formula: C9H10FIN2O5. Mole weight: 372.09. Custom synthesis is available. Send your inquiries for more information. | London |
| 2'-Deoxy-2'-fluoroarabinoadenosine | As an analog of the antitumour and antiviral naturally occurring nucleoside 9-(β-D-arabinofuranosyl)adenine (ara-A), 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine inhibited the growth of T. vaginalis with an IC50 of 0.09μM. Uses: Anti-neoplastic; inhibits the growth of t. vaginalis with an ic50 of 0.09μm. Group: Pharmaceutical. Alternative Names: 20227-41-2;9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)adenine;(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol;arabino-F-Ado;CHEMBL2032002;(2R,3R,4S,5R)-5-(6-AMINOPURIN-9-YL)-4-FLUORO-2-(HYDROXYMETHYL)OXOLAN-3-OL;(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;C10H12FN5O3;SCHEMBL1389499;123334-75-8;BDBM50452569;MFCD12911815;2??-Deoxy-2??-fluoroarabinoadenosine;AKOS027327937;AC-32315;AS-68707;F13969;A855629;2 inverted exclamation mark -Deoxy-2 inverted exclamation mark -fluoroarabinoadenosine;(2R,3R,4S,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol;9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine. CAS No. 20227-41-2. Pack Sizes: 200 mg. Product ID: B0084-086977. Molecular formula: C26H30N2O5. Mole weight: 450.5. Custom synthesis is available. Send your inquiries for more information. | London |
| 2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine | It is the impurity C of Clofarabine and is also an anticancer agent. Group: Pharmaceutical. Alternative Names: 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)guanine; 2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine; 2'-deoxy-2'-fluoro-arabino-guanosine; 2'-FANA-Gr; 2-Amino-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-1H-purin-6(9H)-one; 2-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one; 2'-Fluoro-Arabinoguanosine; NUK-2. CAS No. 103884-98-6. Pack Sizes: 250 mg. Product ID: B2706-081123. Molecular formula: C10H12FN5O4. Mole weight: 285.23. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Deoxy-2-fluoro-L-fucose | 2-Deoxy-2-fluoro-L-fucose, an indispensable compound in the biomedical sector, finds diverse therapeutic applications. Its pivotal role lies in the development of pharmaceutical agents combating ailments like cancer, inflammation, and viral infections. Group: Pharmaceutical. Alternative Names: 2,6-dideoxy-2-fluoro-L-Galactose. CAS No. 70763-62-1. Pack Sizes: 100 mg. Product ID: B1370-225495. Molecular formula: C6H11FO4. Mole weight: 166.15. Custom synthesis is available. Send your inquiries for more information. | London |
| 2'-Deoxy-4'-ethynyl-2-fluoroadenosine | Islatravir (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. Uses: Enzyme inhibitors. Group: Pharmaceutical. Alternative Names: EFdA; 4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine. CAS No. 865363-93-5. Pack Sizes: 10 mg. Product ID: B2705-038148. Molecular formula: C12H12FN5O3. Mole weight: 293.25. Custom synthesis is available. Send your inquiries for more information. | London |
| 2'-Deoxy-5-fluorocytidine | 1g Pack Size. Group: Biochemicals, Building Blocks, Fluorinated Products. Formula: C9H12FN3O4. CAS No. 66335-38-4. Prepack ID : 79755577-1g. Molecular Weight : 245.21. |  |
| (2'R)-2'-deoxy-2'-fluoro-2'-C-methyluridine | PSI-6206 is a selective HCV RNA polymerase inhibitor. It is the unphosphorylated parent compound of triphosphate analog PSI-7409, which is a potent inhibitor of the HCV NS5B RNA dependent RNA polymerase. Group: Pharmaceutical. Alternative Names: RO-2433; RO 2433; RO2433; PSI6206; PSI 6206; PSI-6206; GS331007; GS-331007; GS 331007; 2'-Deoxy-2'-fluoro-2'-C-methyluridine; Sofosbuvir Metabolite GS331007; 1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine; ZL-01 metabolite M9; 2'-Deoxy-2'-Fluoro-2'-methyluridine. CAS No. 863329-66-2. Pack Sizes: 5 g. Product ID: B2693-459960. Molecular formula: C10H13FN2O5. Mole weight: 260.22. Custom synthesis is available. Send your inquiries for more information. | London |
| 3'-Deoxy-3'-fluorocytidine | 3'-Deoxy-3'-fluorocytidine is a purine nucleoside analogue. It is an antiviral agent. Group: Pharmaceutical. Alternative Names: Cytidine, 3-deoxy-3-fluoro-; 3'-Fluoro-3'-deoxycytidine; 1-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)thymine; 4-amino-1-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-3,4-dihydropyrimidin-2(1H)-one; 3'-F-3'-Dc. CAS No. 123402-20-0. Pack Sizes: 5 mg. Product ID: B1370-279821. Molecular formula: C9H12FN3O4. Mole weight: 245.21. Custom synthesis is available. Send your inquiries for more information. | London |
| 3'-Deoxy-3'-fluorouridine | 3'-Deoxy-3'-fluorouridine, a compound of utmost significance in the biomedical industry, assumes a pivotal position in the advancement of antiviral pharmaceuticals targeting RNA virus-associated ailments. This exceptional product showcases its robust antiviral efficacy against a multitude of viruses. Through the powerful mechanism of inhibiting viral replication, 3'-Deoxy-3'-fluorouridine emerges as a propitious contender in the ongoing battle against these formidable infectious maladies. Group: Pharmaceutical. Alternative Names: 3'-Fluoro-3'-deoxyuridine; 1-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)uracil; 1-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. CAS No. 57944-13-5. Pack Sizes: 5 mg. Product ID: B2706-279822. Molecular formula: C9H11FN2O5. Mole weight: 246.19. Custom synthesis is available. Send your inquiries for more information. | London |
| 3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine | 3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine is a highly complex and perplexing compound, playing a pivotal role in combatting viruses. Notably, it showcases exceptional selectivity and efficacy against viral replication and tumor proliferation, thereby emerging as an indispensable asset in the development of antiviral medicines and anticancer researchs. Group: Pharmaceutical. Alternative Names: 1-((2R,3R,4R,5R)-4-((tert-Butyldimethylsilyl)oxy)-3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-Deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluorouridine; Uridine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-; 3'-O-TBDMS-2'-F-dU. CAS No. 1445379-59-8. Pack Sizes: 1 g. Product ID: B1370-072091. Molecular formula: C15H25FN2O5Si. Mole weight: 360.45. Custom synthesis is available. Send your inquiries for more information. | London |
| 5'-Deoxy-5-fluorocytidine | A metabolite of Capecitabine. Group: Pharmaceutical. Alternative Names: 5'-Deoxy-5-fluorocytidine; 5-Fluoro-5'-deoxycytidine; 5'-DFCR; USP Capecitabine Related Compound A; Capecitabine EP Impurity A; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoropyrimidin-2(1H)-one; 4-Amino-1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoropyrimidin-2(1H)-one. CAS No. 66335-38-4. Pack Sizes: 1mg;1g;10g. Product ID: NP2605. Molecular formula: C9H12FN3O4. Mole weight: 245.21. Custom synthesis is available. Send your inquiries for more information. | London |
| 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite | 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a modified phosphoramidite designed for use in the synthesis of stable and efficient RNA and DNA oligonucleotides. Its protective groups and modifications enhance the stability of the resulting nucleic acids and facilitate their incorporation into nucleic acid chains during solid-phase synthesis. This compound is crucial in the production of antisense oligonucleotides, siRNA, probes, and primers, providing enhanced resistance to enzymatic degradation and improved performance in various applications. Group: Pharmaceutical. Alternative Names: 2'-F-dU Phosphoramidite; DMT-2'Fluoro-dU Phosphoramidite; 5'-O-Dimethoxytrityl-2'-fluoro-2'-deoxyuridine 3'-CE phosphoramidite; 2'-Deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-fluorouridine 3-CE phosphoramidite; DMT-2'-Fluoro-dU amidite; 2'-Fluoro-2'-deoxy Uridine CED Phosphoramidite; 2'-Deoxy-5'-O-DMT-2'-fluorouridine 3-CE phosphoramidite; 5'-O-DMT-2'-F-dU 3'-CE phosphoramidite. CAS No. 146954-75-8. Pack Sizes: 5 g. Product ID: B2706-084339. Molecular formula: C39H46FN4O8P. Mole weight: 748.78. Custom synthesis is available. Send your inquiries for more information. | London |
| 5'-O-DMT-2'-fluoro-N2-isobutyryl-2'-Deoxy-guanosine 3'-CE phosphoramidite | 5'-O-DMT-2'-Fluoro-N2-isobutyryl-2'-Deoxy-guanosine 3'-CE phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It features a 5'-dimethoxytrityl (DMT) protecting group at the 5'-hydroxyl position, a 2'-fluoro modification to enhance stability and binding affinity, an N2-isobutyryl group protecting the exocyclic amine of the guanine base, and a cyanoethyl (CE) group on the 3'-phosphoramidite. These modifications make it suitable for synthesizing oligonucleotides with improved resistance to enzymatic degradation and enhanced hybridization properties, which are crucial for applications in research, diagnostics, and therapeutics. Group: Pharmaceutical. Alternative Names: 2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine 3'-CE phosphoramidite; 2'-F-iBu-G-CEP; 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)?-Guanosine 3'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]; DMT-2'Fluoro-dG(iBu) Phosphoramidite; 2'-F-dG(iBu) 3'-CE phosphoramidite; DMT-2'-F-dG(iBu)-CE Phosphoramidite; 2'-F-dG(iBu)-CE Phosphoramidite; 2'-Fluoro-N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine-3'-CE-Phosphoramidite. CAS No. 144089-97-4. Pack Sizes: 5 g. Product ID: B2706-291975. Molecular formula: C44H53FN7O8P. Mole weight: 857.91. Custom synthesis is available. Send your inquiries for more information. | London |
| 5'-O-DMT-5-Fluoro-2'-deoxyuridine-3'-CE Phosphoramidite | 5'-O-DMT-5-Fluoro-2'-deoxyuridine-3'-CE Phosphoramidite is a highly potent reagent for the synthesis of 5-fluorouracil (5-FU) containing oligonucleotides, with potential applications in the treatment of cancer. By boosting the selectivity and efficacy of 5-FU, a well-established chemotherapy drug for different forms of cancer, this compound constitutes a promising avenue to enhance the therapeutic options available to patients. Group: Pharmaceutical. Alternative Names: 5-F-dU Phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-uridine 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; FdU-amidite; NSC-729744. CAS No. 142246-63-7. Pack Sizes: 250 mg. Product ID: B2706-049657. Molecular formula: C39H46FN4O8P. Mole weight: 748.78. Custom synthesis is available. Send your inquiries for more information. | London |
| 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite is a phosphoramidite compound used to introduce 2-fluoro-modified nucleotides into oligonucleotides. Group: Pharmaceutical. Alternative Names: N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite; 2'-F-Ac-dC CE phosphoramide; 2'-F-Ac-dC Phosphoramidite; DMT-2'-F-dC(Ac) amidite; DMT-2'Fluoro-dC(Ac) Phosphoramidite; DMT-2'-F-dC(Ac)-CE Phosphoramidite; N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxycytidine-3'-CE-Phosphoramidite; 2'-Fluoro-2'-deoxy Cytidine (n-ac) CED Phosphoramidite; 5'-O-DMT-2'-F-Acetyl-Deoxycytidine-CE Phosphoramidite; 5'-O-DMT-2'-F-dC(Ac) 3'-CE phosphoramidite. CAS No. 159414-99-0. Pack Sizes: 10 g. Product ID: B2706-395301. Molecular formula: C41H49FN5O8P. Mole weight: 789.83. Custom synthesis is available. Send your inquiries for more information. | London |
| 5'-O-DMT-N4-benzoyl-2'-fluoro-2'-deoxycytidine | 5'-O-DMT-N4-benzoyl-2'-fluoro-2'-deoxycytidine boasts a promising pharmacological arsenal to combat a range of viral infections. With virucidal efficacy that targets the DNA replication machinery of several virus strains, the drug holds considerable therapeutic potential for cases of hepatitis B and C, as well as herpes and shingles. Furthermore, its anti-neoplastic properties make it a noteworthy exploratory tool for certain types of cancer treatment. Group: Pharmaceutical. Alternative Names: 5'-O-(4,4'-dimethoxytrityl)-N4-benzoyl-2'-fluoro-2'-deoxycytidine; N4-Bz-DMT-2'-F-dC; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-D-cytidine; N4-Benzoyl-5'-O-DMT-2'-fluoro-2'-deoxycytidine; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine; 5'-O-DMTr-2'-F-dC(Bz); 5'-DMT-2'-F-Bz-dC; 5'-O-(4,4'-dimethoxytrityl)-N6-Benzoyl-2'-fluoro-2'-deoxyadenosine; N-{1-{5-O-[bis-(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-D-arabinofuranosyl}-1,2-dihydro-2-oxo-4-pyrimidinyl}-benzamide; N-benzoyl-5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-deoxy-2'-fluoro-Cytidine; 5'-O-DMT-N4-Bz-2'-F-dC. CAS No. 146954-77-0. Pack Sizes: 5 g. Product ID: B1370-376765. Molecular formula: C37H34FN3O7. Mole weight: 651.68. Custom synthesis is available. Send your inquiries for more information. | London |
| N2-iso-Butyroyl-3'-deoxy-3'-fluoroguanosine | N2-iso-Butyroyl-3'-deoxy-3'-fluoroguanosine, a crucial compound in the field of biomedicine, showcases its potency as an effective antiviral agent targeted at treating viral infections resulting from the influenza virus. By virtue of its distinct chemical characteristics, it displays remarkable capability in hindering viral replication and alleviating the severity of influenza-related symptoms. Group: Pharmaceutical. Alternative Names: 3'-Deoxy-3'-fluoro-N-isobutyrylguanosine; Guanosine, 3'-deoxy-3'-fluoro-N-(2-methyl-1-oxopropyl)-; N-(9-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide. CAS No. 2080404-20-0. Pack Sizes: 5 mg. Product ID: B1370-125991. Molecular formula: C14H18FN5O5. Mole weight: 355.32. Custom synthesis is available. Send your inquiries for more information. | London |
| N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-deoxy-3'-fluoroguanosine | N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-deoxy-3'-fluoroguanosine, a biomedical compound, demonstrates its effectiveness in targeting and treating specific diseases. Its therapeutic potential and precise mechanism of action can be explored through the referenced websites, providing comprehensive information concerning drug interactions and its efficacy in addressing various medical conditions. Group: Pharmaceutical. Alternative Names: 5'-O-DMT-N2-isobutyryl-3'-Fluoro-3'-deoxyguanosine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-deoxy-3'-fluoro-N-isobutyrylguanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-3'-fluoro-N-(2-methyl-1-oxopropyl)guanosine; N-(9-((2R,3S,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; 5'-O-DMT-N2-ibu-3'-F-3'-dG; 5'-O-DMT-3'-F-dG(iBu). CAS No. 2080404-19-7. Pack Sizes: 10 mg. Product ID: B1370-127007. Molecular formula: C35H36FN5O7. Mole weight: 657.69. Custom synthesis is available. Send your inquiries for more information. | London |
| N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite | N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite can be used to incorporate 2-fluoro modified nucleotides into oligonucleotides, improving metabolic stability. Group: Pharmaceutical. Alternative Names: 2'-Fluoro-dA CEP; 2'-Fluoro-Bz-A-CEP; N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-D-adenosine 3'-CE phosphoramidite; N6-Benzoyl-5'-O-DMT-2'-fluoro-2'-deoxyadenosine 3'-CE phosphoramidite; DMT-2'-F-dA(Bz)-CE-Phosphoramidite; N6-Bz-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxyadenosine-3'-CE-Phosphoramidite; N6-Benzoyl-5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoroadenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite. CAS No. 136834-22-5. Pack Sizes: 10 g. Product ID: B2706-291972. Molecular formula: C47H51FN7O7P. Mole weight: 875.95. Custom synthesis is available. Send your inquiries for more information. | London |
| N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE-phosphoramidite | N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE-phosphoramidite is an antiviral agent that inhibits the replication of DNA. Group: Pharmaceutical. Alternative Names: N6-Bz-5'-O-DMTr-2'-fluoro-2'-deoxyarabinoadenosine-3'-CEN-phosphoramidite; 2'-Fluoro-2'-deoxy-ara-A(Bz)-3'-phosphoramidite; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxyarabinoadenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 5'-O-DMT-N6-Benzoyl-2'-fluoro-2'-arabinofuranosyl-2'-deoxyadenosine 3'-CE phosphoramidite; 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl}-6-{[hydroxy(phenyl)methylene]amino}-9H-purine; 2'-F-A(Bz)-ANA-CE-Phosphoramidite; 5'-Dimethoxytrityl-N6-benzoyl-2'-deoxy-2'-fluoroarabinoadenosine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2'-FANA-A(Bz) Phosphoramidite. CAS No. 329187-86-2. Pack Sizes: 1 g. Product ID: B2706-291985. Molecular formula: C47H51FN7O7P. Mole weight: 875.92. Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-2-deoxy-2-fluoro-D-glucose (sodium salt) | UDP-2-deoxy-2-fluoro-D-glucose is an indispensable compound, serving as a potent tool in positron emission tomography (PET) imaging. By virtue of its radiochemical attributes, this glucose analog enables the non-intrusive observation of in vivo glucose metabolism. Its application extends to the research of multifarious conditions encompassing cancer, neurodegenerative ailments and infectious pathologies. Group: Pharmaceutical. Alternative Names: Uridine-2-deoxy-2-fluoro-D-glucose diphosphate ester. CAS No. 67341-43-9. Pack Sizes: 25 mg. Product ID: B1370-002274. Molecular formula: C15H23FN2O16P2. Mole weight: 568.29. Custom synthesis is available. Send your inquiries for more information. | London |
| 2,3,4,6-Tetra-O-acetyl-a-D-glucopyranosyl fluoride | 2,3,4,6-Tetra-O-acetyl-a-D-glucopyranosyl fluoride, a glycosyl fluoride, serves as a significant donor substrate for synthesizing complex carbohydrates. Employing this compound enzymatically generates various α-linked glycoconjugates for experimental and pharmacological purposes. Additionally, its application extends to investigations regarding the enzymatic mechanisms implicated in the metabolism of the carbohydrate. Group: Pharmaceutical. Alternative Names: Acetofluoro-a-D-glucose; (2R,3R,4S,5R,6R)-2-(Acetoxymethyl)-6-fluorotetrahydro-2H-pyran-3,4,5-triyl triacetate; 1-Fluoro-1-deoxy-alpha-D-glucopyranose tetraacetate; α-D-Glucopyranosyl fluoride 2,3,4,6-tetraacetate. CAS No. 3934-29-0. Pack Sizes: 5 g. Product ID: B1370-371910. Molecular formula: C14H19FO9. Mole weight: 350.29. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Hydroxymethyl-2'-deoxyuridine | 5-(Hydroxymethyl)-2'-deoxyuridine is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 μM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 μM). 5-(Hydroxymethyl)-2'-deoxyuridine acts synergistically with 5-fluorouracil (5-FU) against HT-29, HCT116, PANC-1, and EKVX cancer cells with no effect on WI38 embryonic lung fibroblasts. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: 5-Hydroxymethyl-2'-deoxyuridine;5116-24-5;alpha-Hydroxythymidine;5-Hydroxymethyldeoxyuridine;2'-Deoxy-5-(hydroxymethyl)uridine;HMdU;5-HMdU;alpha-Hydroxy-thymidin;Thymidine, alpha-hydroxy-;CHEBI:61288;Uridine, 2'-deoxy-5-(hydroxymethyl)-;2'-Deoxy-5-hydroxymethyluridine;5-Hydroxymethyl-deoxyuridine;EJZ33W33JN;1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidine-. CAS No. 5116-24-5. Pack Sizes: 1 g. Product ID: B1370-120698. Molecular formula: C14H11N5O2S. Mole weight: 313.34. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Iodo-2'-deoxytubercidin | It is a derivative of 7-Iodo-7-deazadenine and is designed to be incorporated into DNA by using Vent(exo-) polymerase primers extension. Uses: Pharmaceutical intermediates. Group: Pharmaceutical. Alternative Names: 4-Amino-5-iodo-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 2'-Deoxy-7-fluorotubercidin; 7-Iodo-7-deaza-2'-deoxyadenosine; 7-Deaza-2'-deoxy-7-iodoadenosine; 7-Iodo-2'-deoxy-7-carbaadenosine; (2R,3S,5R)-5-(4-Amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine. CAS No. 166247-63-8. Pack Sizes: 500 mg. Product ID: B0001-331316. Molecular formula: C11H13IN4O3. Mole weight: 376.15. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Methyl-2'-Fluoro-U Phosphoramidite | 5-Methyl-2'-Fluoro-U Phosphoramidite, a pivotal compound with paramount significance in the domain of biomedicine, assumes the role of a fundamental constituent within the intricate framework of synthesized nucleic acids. Its exceptional utility lies in its indispensable contribution to the progressive advancement of antisense oligonucleotide development. Notably, this phosphoramidite possesses an intrinsic capacity to effectively combat a myriad of ailments encompassing viral infections and genetic disorders, by selectively targeting specified genes or RNA sequences. Group: Pharmaceutical. Alternative Names: 5-Me-5'-O-DMT-2'-fluoro-2'-Deoxyuridine 3'-CE phosphoramidite; 2'-F T amidite; 2'-Fluoro-dT Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-5-methyluridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 2'-Fluoro-5MeU-3'-phosphoramidite; DMTr-2'-F-dT-3'-CE-Phosphoramidite; DMT-5-Me-2'-F-dU-CE-Phosphoramidite. CAS No. 182700-06-7. Pack Sizes: 5 g. Product ID: B1370-288524. Molecular formula: C40H48FN4O8P. Mole weight: 762.82. Custom synthesis is available. Send your inquiries for more information. | London |
| Acetobromo-alpha-D-glucuronic Acid Methyl Ester | Acetobromo-alpha-D-glucuronic Acid Methyl Ester is a useful compound for preparing a fluorogenic probe for human heparanase. Uses: It is a useful compound for preparing a fluorogenic probe for human heparanase. Group: Pharmaceutical. Alternative Names: Methyl(tri-O-acetyl-α-D-glucopyranosyl bromide)uronate; (2S,3S,4S,5R,6R)-3,4,5-triacetyloxy-6-bromo-2-oxanecarboxylic acid methyl ester; 1-Bromo-1-deoxy-2,3,4-triacetate α-D-Glucopyranuronic Acid Methyl Ester; Methyl 2,3,4-Tri-O-acetyl-1-bromo-1-deoxy-α-D-glucopyranuranate; Methyl α-Acetobromoglucuronate. CAS No. 21085-72-3. Pack Sizes: 5 g. Product ID: B2705-174281. Molecular formula: C13H17BrO9. Mole weight: 397.17. Custom synthesis is available. Send your inquiries for more information. | London |
| α-D-Glucopyranosyl Fluoride | α-D-Glucopyranosyl Fluoride is a key compound used in biomedicine for synthesizing various fluorinated carbohydrates and glycoconjugates. It plays a vital role in the development of novel drugs, diagnostics, and vaccines targeting metabolic disorders, such as diabetes, by modulating carbohydrate metabolism pathways. Group: Pharmaceutical. Alternative Names: alpha-D-Glucopyranosyl fluoride; 1-Fluoro-1-deoxy-α-D-glucose. CAS No. 2106-10-7. Pack Sizes: 250 mg. Product ID: B2705-150539. Molecular formula: C6H11FO5. Mole weight: 182.15. Custom synthesis is available. Send your inquiries for more information. | London |
| Azvudine | Azvudine is a nucleoside reverse transcriptase inhibitor (NRTI), which exhibits inhibtory effects on HIV, HBV and HCV. Group: Pharmaceutical. Alternative Names: 4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinocytidine; 4'-Azido-2'-deoxy-2'-fluoroaracytidine; RO-0622; 4-amino-1-((2R,3S,4R,5R)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 2'-deoxy-2'-β-fluoro-4'-azidocytidine; 1-(4'-azido-2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)cytosine. CAS No. 1011529-10-4. Pack Sizes: 5 mg. Product ID: B2693-338891. Molecular formula: C9H11FN6O4. Mole weight: 286.22. Custom synthesis is available. Send your inquiries for more information. | London |
| Capecitabine | Capecitabine inhibits tumor growth and metastatic recurrence after resection of human hepatocellular carcinoma (HCC) in highly metastatic nude mice model. It is a chemotherapy medication used to treat breast cancer, gastric cancer and colorectal cancer. Group: Pharmaceutical. Alternative Names: 5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine; [1-(5-Deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl]carbamic Acid Pentyl Ester; Capecytabine; Capiibine; Captabin; Ro 09-1978; Xeloda; Pentyl 1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate. CAS No. 154361-50-9. Pack Sizes: 10 g. Product ID: BBF-05852. Molecular formula: C15H22FN3O6. Mole weight: 359.35. Custom synthesis is available. Send your inquiries for more information. | London |
| Capecitabine-2',3'-cyclic carbonate | Capecitabine related compound C is an impurity in Capecitabine, an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine ). Group: Pharmaceutical. Alternative Names: 5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine Cyclic 2',3'-Carbonate. CAS No. 921769-65-5. Pack Sizes: 1mg;1g;10g. Product ID: NP3711. Molecular formula: C16H20FN3O7. Mole weight: 385.35. Custom synthesis is available. Send your inquiries for more information. | London |
| Capecitabine 2',3'-diacetate | A metabolite of Capecitabine. Group: Pharmaceutical. Alternative Names: 5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine 2',3'-Diacetate; [1-(2,3-Di-O-acetyl-5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl]carbamic Acid Pentyl Ester. CAS No. 162204-20-8. Pack Sizes: 1mg;1g;10g. Product ID: NP3684. Molecular formula: C19H26FN3O8. Mole weight: 443.43. Custom synthesis is available. Send your inquiries for more information. | London |
| Capecitabine impurity D | A Capecitabine analog which shows antitumor activity. Group: Pharmaceutical. Alternative Names: 5'-Deoxy-5-fluoro-N4-[(2-methylbutoxy)carbonyl]cytidine; 5'-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine; Capecitabine EP Impurity D; 2-Methylbutyl (1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate; 5'-Deoxy-5-fluoro-N4-(2-methyl-1-butyloxycarbonyl)cytidine. CAS No. 910129-15-6. Pack Sizes: 25 mg. Product ID: B0246-468068. Molecular formula: C15H22FN3O6. Mole weight: 359.35. Custom synthesis is available. Send your inquiries for more information. | London |
| Capecitabine impurity F | It is an impurity of Capecitabine and is used as an antitumor agent. Group: Pharmaceutical. Alternative Names: 5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine; [1-(5-Deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl]-carbamic Acid 3-Methylbutyl Ester; 5'-Deoxy-5-fluoro-N-[(3-methylbutoxy)carbonyl]cytidine; Isopentyl (1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate; 5'-Deoxy-5-fluoro-N4-(3-methyl-1-butyloxycarbonyl)cytidine; Capecitabine impurity E. CAS No. 162204-30-0. Pack Sizes: 25 mg. Product ID: B0246-468069. Molecular formula: C15H22FN3O6. Mole weight: 359.35. Custom synthesis is available. Send your inquiries for more information. | London |
| Clevudine | Clevudine is an inhibitor of hepatitis B virus (HBV). It is metabolized in cells by the cellular thymidine kinase as well as deoxycytidine kinase to its monophosphate, and subsequently to the di- and triphosphate, which are biologically active. Uses: Antiviral agents. Group: Pharmaceutical. Alternative Names: 1-(2'-Deoxy-2'-fluoro-β-L-arabinofuranosyl)-5-methyluracil; L-FMAU; 1-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; L FMAU; LFMAU; Levovir; 2'-Fluoro-5-methyl-b-L-arabinofuranosyluracil. CAS No. 163252-36-6. Pack Sizes: 1 g. Product ID: B0084-085286. Molecular formula: C10H13FN2O5. Mole weight: 260.22. Custom synthesis is available. Send your inquiries for more information. | London |
| Doxifluridine | Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM. Uses: Antimetabolites, antineoplastic. Group: Pharmaceutical. Alternative Names: Doxifluridine; 5'-deoxy-5-fluorouridine; Furtulon; Flutron; doxyfluridine; 5'-Doxifluridine; 5-Fluorodeoxyuridine; USP Capecitabine Related Compound B; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 1-(beta-D-5-Desoxyribofuranoxyl)-5-fluoruracil. CAS No. 3094-9-5. Pack Sizes: 1mg;1g;10g. Product ID: NP2604. Molecular formula: C9H11FN2O5. Mole weight: 246.194. Custom synthesis is available. Send your inquiries for more information. | London |
| Fiacitabine | Fiacitabine is a selective inhibitior of DNA replication of herpes simplex virus(HSV). It was active at much lower concentrations than arabinosylcytosine, iododeoxyuridine, and arabinosyladenine. It was slightly more active against herpes simplex virus type 1 than acycloquanosine and slightly more toxic to normal cells. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodocytosine; 5-Iodo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine; FICA; DRG-0077; DRG 0077; DRG0077; FOAC; Fluoroiodoaracytidine; Fluorviodoaracytidine; 4-Amino-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one; 1-β-D-2'-Fluoroarabino-5-iodocytosine; 2'-Fluoro-5-iodo-1-β-D-arabinofuranosylcytosine; NSC 382097. CAS No. 69123-90-6. Pack Sizes: 10 mg. Product ID: B2693-097087. Molecular formula: C9H11FIN3O4. Mole weight: 371.1. Custom synthesis is available. Send your inquiries for more information. | London |
| Fitusiran | Fitusiran, a small interfering RNA, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. It increases thrombin generation and has the potential for the research of the hemophilia. Group: Pharmaceutical. Alternative Names: ALN-AT3SC; SAR439774; RNA, ((2'-deoxy-2'-fluoro)G-sp-Gm-sp-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)A-Um-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)A),3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-Dgalactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)U-sp-Gm-(2'-deoxy2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)A-Um-Gm-Gm-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)C-Cm-sp-Am-sp-Gm). CAS No. 1499251-18-1. Pack Sizes: 1 mg. Product ID: B1370-072729. Custom synthesis is available. Send your inquiries for more information. | London |
| Fosaprepitant-[d4] Dimeglumine | Fosaprepitant-[d4] Dimeglumine is a labelled form of Fosaprepitant Dimeglumine, which has been found to be a selective neurokinin-1 (NK-1) receptor antagonist. Group: Pharmaceutical. Alternative Names: [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl-d4)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol; Fosaprepitant D4 Dimeglumine; MK-0517-d4; L785298-d4. Pack Sizes: 25 mg. Product ID: BLP-005503. Molecular formula: C37H52D4F7N6O16P. Mole weight: 1008.86. Custom synthesis is available. Send your inquiries for more information. | London |
| Givosiran sodium | Givosiran sodium is a small interfering RNA (siRNA) directed towards delta-aminolevulinate synthase 1 (ALAS1). Givosiran sodium has been indicated for the treatment of adults with acute hepatic porphyria (AHP). Group: Pharmaceutical. Alternative Names: ALN-AS1 sodium; ALN AS1 sodium; ALN-AS 1 sodium; WHO 10280 sodium; WHO-10280 sodium; WHO10280 sodium; Givlaari sodium; RNA, (Cm-sp-Am-sp-Gm-Am-Am-Am-(2'-deoxy-2'-fluoro)G-Am-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)C-Am-Um-Cm-Um-Um-Am), 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)A-sp-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)G-Am-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)U-Cm-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)U-Cm-(2'-deoxy-2'-fluoro)U-Gm-sp-Gm-sp-Um) (1:1) sodium salt. Pack Sizes: 10 mg. Product ID: B1370-212888. Molecular formula: C524H651F16N173Na43O316P43S6. Mole weight: 17,245.56 Da. Custom synthesis is available. Send your inquiries for more information. | London |
| Inclisiran | Inclisiran is a medication approved for the treatment of people with atherosclerotic cardiovascular disease (ASCVD), ASCVD risk equivalents and heterozygous familial hypercholesterolemia (HeFH). It is a small interfering RNA (siRNA) that binds to PCSK9 messenger RNA, resulting in decreased concentrations of PCSK9 and plasma concentrations of LDL cholesterol. Group: Pharmaceutical. Alternative Names: ALN-PCSsc; ALN-60212; Leqvio; Inclisiran sodium; ALN-PCS; Leqvio; RNA, (Am-sp-(2'-deoxy-2'-fluoro)C-sp-Am-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)C-Um-Am-Gm-sp-Am-sp-Am), complex with RNA (Cm-sp-Um-sp-Am-Gm-Am-Cm-(2'-deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)G-Um-dT-Um-Um-Gm-Cm-Um-Um-Um-Um-Gm-Um) 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate] (1:1). CAS No. 1639324-58-5. Pack Sizes: 5 mg. Product ID: B1370-057828. Molecular formula: C529H707F12N176O316P43S6. Mole weight: 16339.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Lumasiran | Lumasiran is a siRNA product that reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1). Group: Pharmaceutical. Alternative Names: ALN-G01; RNA, (Gm-sp-Am-sp-Cm-Um-Um-Um-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-Um-Gm-Gm-Am-Am-Am-Um-Am-Um-Am), 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)A-sp-Um-Am-Um-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-Am-Gm-Gm-Am-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)A-Am-Am-Gm-Um-Cm-sp-Cm-sp-Am) (1:1). CAS No. 1834610-13-7. Pack Sizes: 5 mg. Product ID: B1370-072716. Molecular formula: C530H712F10N173O320P43S6. Mole weight: 16,340 Da. Custom synthesis is available. Send your inquiries for more information. | London |
| PSI 7411 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Group: Pharmaceutical. Alternative Names: 5'-Uridylic acid, 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)?-; (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylic acid; PSI-7411; PSI7411; 2'-Fluoro-2'-methyl(up)-uridine-5'-monophosphate; 2'-F-2'-Me(up)-UMP; Sofosbuvir Impurity 34 (GS-606965). CAS No. 1015073-43-4. Pack Sizes: 10 mg. Product ID: B2694-479716. Molecular formula: C10H14FN2O8P. Mole weight: 340.2. Custom synthesis is available. Send your inquiries for more information. | London |
| PSI-7976 | PSI-7976 is an inhibitor of HCV RNA replication with EC50 value of 1.07μM. PSI-7851 is a phosphoramidate prodrug of PSI-7411 and has potent anti-hepatitis C virus (HCV) activity. It is a mixture of two diastereoisomers. PSI-7976 is one of them. Another one is PSI-7977. PSI-7851 is firstly activated through being hydrolyzed by CatA and CES1in the liver cells. It is found that CatA prefers PSI-7977 as a substrate over PSI-7976 while CES1 preferentially hydrolyzes PSI-7976 over PSI-7977. Since CES1 does not express in clone A replicon cells, the ability of PSI-7976 and PSI-7977 to inhibit HCV RNA replication is different in these cells. PSI-7977 is more potent than PSI-7976 with EC50 value of 92nM. Group: Pharmaceutical. Alternative Names: Sofosbuvir (R)-Phosphate; (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate; N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester. CAS No. 1190308-01-0. Pack Sizes: 25 mg. Product ID: B2693-463118. Molecular formula: C22H29FN3O9P. Mole weight: 529.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Sofosbuvir | Sofosbuvir is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Uses: Antiviral agents. Group: Pharmaceutical. Alternative Names: PSI-7977; PSI 7977; PSI7977; GS7977; GS-7977; GS 7977; Sovaldi; N-[[P(S),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine, 1-methylethyl ester; Hepcinat; Hepcvir; Resof; SoviHep. CAS No. 1190307-88-0. Pack Sizes: 2.5 g. Product ID: B0084-457411. Molecular formula: C22H29FN3O9P. Mole weight: 529.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Sofosbuvir Impurity (GS-566500) | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Group: Pharmaceutical. Alternative Names: L-Alanine, N-[(2'R)?-2'-deoxy-2'-fluoro-2'-methyl-5'-uridylyl]?-; N-[(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylyl]-L-alanine; PSI 352707. CAS No. 1233335-78-8. Pack Sizes: 10 mg. Product ID: B2694-479704. Molecular formula: C13H19FN3O9P. Mole weight: 411.28. Custom synthesis is available. Send your inquiries for more information. | London |
| TAS4464 | TAS4464 is a potent and selective NEDD8 activating enzyme (NAE) inhibitor with IC50 of 0.955 nM. It selectively inhibits NAE relative to the other E1s UAE and SAE. TAS4464 treatment inhibits cullin neddylation and subsequently induces the accumulation of CRL substrates such as CDT1, p27, and phosphorylated IkBa in human cancer cell lines. Group: Pharmaceutical. Alternative Names: 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-[5-[(aminosulfonyl)amino]-5-deoxy-beta-D-ribofuranosyl]-5-[2-(2-ethoxy-6-fluorophenyl)ethynyl]-. CAS No. 1848959-10-3. Pack Sizes: 5 mg. Product ID: B2693-010141. Molecular formula: C21H23FN6O6S. Mole weight: 506.5. Custom synthesis is available. Send your inquiries for more information. | London |
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