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| Product | Description | |
|---|---|---|
| Demethylcephalotaxinone | Demethylcephalotaxinone is a natural alkaloid compound found in several plants. Group: Pharmaceutical. CAS No. 51020-45-2. Pack Sizes: 1 mg. Product ID: NP0287. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Demethylmurrayanine | Demethylmurrayanine is a natural alkaloid found in the herbs of Clausena dunniana. Group: Pharmaceutical. CAS No. 123497-84-7. Pack Sizes: 5 mg. Product ID: NP0288. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Demethylvestitol | Demethylvestitol is a flavonoid isolated from the herbs of Spatholobus suberectus. Uses: Neuromuscular nondepolarizing agents. Group: Pharmaceutical. CAS No. 65332-45-8. Pack Sizes: 1 mg. Product ID: NP2167. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Demethylzeylasteral | Demethylzeylasteral is extracted from the herb of Tripterygium wilfordii Hook.f. It may be used as an immunosuppressive agent in the fields of organ transplantation and autoimmune disorders. It could increase both activation and inactivation time constants of Ca(2+) currents. Group: Pharmaceutical. CAS No. 107316-88-1. Pack Sizes: 20 mg. Product ID: NP6999. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 12-Demethylneocaesalpin F | 12-Demethylneocaesalpin F is a diterpenoid found in Caesalpinia. Group: Pharmaceutical. CAS No. 1228964-10-0. Pack Sizes: 1 mg. Product ID: NP1652. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (17R,19E,21alpha)-17-acetoxy-1,2,19,20-tetradehydro-1-demethylajmalan-21-yl beta-D-glucopyranoside | Raucaffricine is a natural alkaloid found in the root of Rauvolfia serpentina. Group: Pharmaceutical. CAS No. 31282-07-2. Pack Sizes: 5 mg. Product ID: NP0398. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 4'-Demethyl-3,9-dihydroeucomin | 4'-Demethyl-3,9-dihydroeucomin is isolated from the herbs of Scilla scilloides. Group: Pharmaceutical. CAS No. 107585-77-3. Pack Sizes: 5 mg. Product ID: NP2156. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 4'-Demethyl epi-Podophyllotoxin (DMEP) | 4'-Demethylepipodophyllotoxin is a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer drugs. It is a potent inhibitor of microtubule assembly. Group: Pharmaceutical. CAS No. 6559-91-7. Pack Sizes: 25 g. Product ID: NP4181. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Demethyltraxillaside | Trachelospermum asiaticum is the origin of 4-Demethyltraxillaside, an organic element with anti-inflammatory and anti-cancer attributes. Functioning as a feasible therapy for multiple illnesses, consisting of liver cancer, Alzheimer's disease, and colon cancer, the compound has substantiated its efficacy against diverse illnesses. Its organic synthesis and pharmacological activities warrant thorough examination and replication. Group: Pharmaceutical. CAS No. 1691201-82-7. Pack Sizes: 1 mg. Product ID: NP4069. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Demethylnobiletin | 5-Demethylnobiletin is a natural flavonoid compound isolated from the peel of Citrus nobilis Lour. Group: Pharmaceutical. CAS No. 2174-59-6. Pack Sizes: 20 mg. Product ID: NP2521. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 6-Epidemethylesquirolin D | 6-Epidemethylesquirolin D is isolated from the herbs of Coleus forskohlii. Group: Pharmaceutical. CAS No. 165074-00-0. Pack Sizes: 1 mg. Product ID: NP1569. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 8-O-Demethyl-7-O-methyl-3,9-dihydropunctatin | 8-O-Demethyl-7-O-methyl-3,9-dihydropunctatin is isolated from the herbs of Scilla scilloides. Group: Pharmaceutical. CAS No. 93078-83-2. Pack Sizes: 5 mg. Product ID: NP2364. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Didemethyl citalopram | Didemethyl citalopram is a metabolite of Citalopram, an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant. Group: Pharmaceutical. CAS No. 62498-69-5. Pack Sizes: 500 mg. Product ID: B2694-039823. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isodemethylwedelolactone | Isodemethylwedelolactone is isolated from the Eclipta prostrata. Group: Pharmaceutical. CAS No. 350681-33-3. Pack Sizes: 25 mg. Product ID: B2703-465887. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Demethyl Olanzapine | N-Demethyl Olanzapine is an impurity of olanzapine, which is a 5-HT2A receptor antagonist used as an antipsychotic medication. Group: Pharmaceutical. CAS No. 161696-76-0. Pack Sizes: 100 mg. Product ID: B0067-060204. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| O-Demethylforbexanthone | O-Demethylforbexanthone isolated from the herbs of Garcinia cowa. Group: Pharmaceutical. CAS No. 92609-77-3. Pack Sizes: 1 mg. Product ID: NP7282. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (R)-O-Demethylmetoprolol | (R)-O-Demethylmetoprolol is an impurity of Betaxolol, which is a selective beta1 adrenergic receptor blocker for the treatment of hypertension and glaucoma. Group: Pharmaceutical. CAS No. 131564-70-0. Pack Sizes: 100 mg. Product ID: B0436-284904. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-O-Demethylmetoprolol | (S)-O-Demethylmetoprolol is an impurity of Betaxolol, which is a selective beta1 adrenergic receptor blocker for the treatment of hypertension and glaucoma. Group: Pharmaceutical. CAS No. 131564-69-7. Pack Sizes: 100 mg. Product ID: B0436-284903. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Hydroxymethyldeoxyuridylate | 5-Hydroxymethyldeoxyuridylate is a pivotal nucleotide in DNA bioresearch and repair, emerging as a substrate indispensable for diverse enzymes implicated in DNA methylation and demethylation cascades. Group: Pharmaceutical. CAS No. 5238-86-8. Pack Sizes: 10 mg. Product ID: B1370-376869. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Demeclocycline hydrochloride | Demethylchlorotetracycline is an antibiotic produced by Streptomyces viridifaciens and Str. aureofaciens S-604. It has antibacterial and anti-insect activity. Group: Pharmaceutical. CAS No. 64-73-3. Pack Sizes: 10 g. Product ID: BBF-02574. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Disodium (R)-2-Hydroxyglutarate | Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM. In U-87MG cells, (R)-2-Hydroxyglutarate acts as a weak antagonist of α-KG to inhibit α-KG-dependent histone demethylases and increase dimethylation on both H3K9 and H3K79. Group: Pharmaceutical. CAS No. 103404-90-6. Pack Sizes: 100 mg. Product ID: BAT-008968. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Efinaconazole | Efinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). Efinaconazole acts as a 14α-demethylase inhibitor. Efinaconazole inhibits fungal lanosterol 14α-demethylase involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. Efinaconazole has been shown to be active against isolates of the following microorganisms, both in vitro and in clinical infections. Efinaconazole exhibits in vitro minimum inhibitory concentrations (MICs) of 0.06 μg/mL or less against most ( ≥ 90%) isolates of the following microorganisms: Trichophyton rubrum; Trichophyton mentagrophytes. Group: Pharmaceutical. CAS No. 164650-44-6. Pack Sizes: 50 mg. Product ID: B0084-463563. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Fluconazole | Fluconazole is a triazole antifungal agent that is effective against most Candida strains. Fluconazole is a fungal lanosterol 14 alpha-demethylase inhibitor used in the treatment and prevention of superficial and systemic fungal infections. Group: Pharmaceutical. CAS No. 86386-73-4. Pack Sizes: 10 g. Product ID: BBF-04628. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Fosfluconazole | Fluconazole, a water-soluble phosphate prodrug of fluconazole, is a triazole antifungal agent that is effective against most Candida strains. Uses: 14-alpha demethylase inhibitors. Group: Pharmaceutical. CAS No. 194798-83-9. Pack Sizes: 100 mg. Product ID: B2692-062094. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MIBG hemisulfate | MIBG hemisulfate is a radiopharmaceutical used in a scintigraphy method called MIBG scan. It demethylates and oxidizes membrane-associated DNA for the treatment of certain kinds of cancer of the adrenal glands. Uses: Antitumor agent. Group: Pharmaceutical. CAS No. 87862-25-7. Pack Sizes: 100 mg. Product ID: B2693-192771. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ORY-1001 dihydrochloride | ORY-1001 is a lysine specific demethylase 1 inhibitor under the development of Oryzon with IC50 value < 20nM. It selectively inhibits related FAD dependent aminoxidases (MAO-A/B, IL4I1, KDM1B> 100uM, SMOX 7uM). ORY-1001 can induce apoptosis in THP-1 and inhibit proliferation and colony formation of MV(4;11) (MLL-AF4) cells (EC50 <1nM). In THP-1 (MLL-AF9) cells, ORY-1001 results in a time-dose dependent me2H3K4 accumulation at KDM1A target genes and concomitant induction of differentiation markers. Group: Pharmaceutical. CAS No. 1431326-61-2. Pack Sizes: 50 mg. Product ID: B0084-470857. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Posaconazole | Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Uses: For research used only. Group: Pharmaceutical. CAS No. 171228-49-2. Pack Sizes: 500 mg. Product ID: B0084-060834. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Posaconazole-[d5] | Posaconazole-[d5], is the labelled analogue of Posaconazole, which is a sterol C14α demethylase inhibitor with an IC50 of 0.25 nM. Posaconazole is a triazole antifungal medication. Group: Pharmaceutical. CAS No. 1217785-83-5. Pack Sizes: 1 mg. Product ID: BLP-003857. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Posaconazole Diastereoisomer 1 (R,R,R,R) | Posaconazole Diastereoisomer 1 (R,R,R,R) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Group: Pharmaceutical. CAS No. 170985-61-2. Pack Sizes: 5 mg. Product ID: B0230-007242. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Posaconazole Diastereoisomer Related Compound 1 | Posaconazole Diastereoisomer Related Compound 1 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Group: Pharmaceutical. CAS No. 159811-30-0. Pack Sizes: 5 mg. Product ID: B0230-478993. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Posaconazole Diastereoisomer Related Compound 2 | Posaconazole Diastereoisomer Related Compound 2 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Group: Pharmaceutical. CAS No. 166583-12-6. Pack Sizes: 25 mg. Product ID: B0230-478994. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Posaconazole Diastereoisomer Related Compound 5 | Posaconazole Diastereoisomer Related Compound 5 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Group: Pharmaceutical. CAS No. 149809-42-7. Pack Sizes: 5 mg. Product ID: B0230-478995. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Posaconazole Diastereoisomer (S,R,S,S) | Posaconazole Diastereoisomer (S,R,S,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Group: Pharmaceutical. CAS No. 213381-02-3. Pack Sizes: 5 mg. Product ID: B0230-007243. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Posaconazole Impurity 33 Oxalate | Posaconazole Impurity 33 Oxalate is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Group: Pharmaceutical. CAS No. 1887197-42-3. Pack Sizes: 25 g. Product ID: B2694-352573. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Seneciphylline | Seneciphylline, a natural pyrrolizidine alkaloid isolated from the herbs of Senecio scandens, may cause reduction of cytochrome P-450 and related monooxygenase activities. Seneciphylline is a pyrrolizidine alkaloid with the potential to affect hepatic drug metabolizing enzymes in rat cells. In vitro, seneciphylline has no effection on hepatic drug metabolizing enzymes, but has seneciphyllineslight activity of reducing aminopyrine demethylase. Group: Pharmaceutical. CAS No. 480-81-9. Pack Sizes: 10 mg. Product ID: NP0002. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tetrahydropiperine | Tetrahydropiperine is a piperine alkaloid originally isolated from P. longum. It acts as an agonist of transient receptor potential vanilloid type 1 (TRPV1). It inhibits the cytochrome P450 (CYP) isoform CYP1A1/arylhydrocarbon hydroxylase (AHH) and 7-methoxycoumarin O-demethylase (MOCD) activity in rat liver microsomes. Group: Pharmaceutical. CAS No. 23434-88-0. Pack Sizes: 100 mg. Product ID: B2703-059108. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| VT-1161 | VT-1161 is a 14-alpha demethylase inhibitor as a tetrazole antifungal agent originated by Viamet Pharmaceuticals. VT-1161 shows potent efficacy in treatment of dermatophytosis in a guinea pig model. Phase II clinical trials for the treatment of Onychomycosis and Vulvovaginal candidiasis is on-going. Uses: Onychomycosis; vulvovaginal candidiasis. Group: Pharmaceutical. CAS No. 1340593-59-0. Pack Sizes: 10 mg. Product ID: B2693-475325. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (Z)-JIB-04 | (Z)-JIB-04 is a Z-isomer of JIB-04, which is a small-molecule histone demethylase inhibitor with antitumor activity. JIB-04 selectively inhibits tumor growth via targeting various tumorigenic signaling pathways. Group: Pharmaceutical. CAS No. 199596-24-2. Pack Sizes: 50 mg. Product ID: B0084-284797. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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