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| Product | Description | |
|---|---|---|
| Deacetylasperulosidic acid | Deacetylasperulosidic acid is a natural compound found in Morinda citrifolia fruit with antioxidant activity. Deacetylasperulosidic acid inhibited the reduction of ear swelling, and also cancelled the suppression of IL-2 production along with the activation of natural killer cells in the same manner as that of Noni-ext. Group: Pharmaceutical. CAS No. 14259-55-3. Pack Sizes: 25 mg. Product ID: B1370-452428. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Deacetyl ganoderic acid F | Deacetyl ganoderic acid F, a natural triterpenoid compound obtained from the Ganoderma lucidum, displays an array spectrum of pharmacological activities, particularly antitumor, immunomodulatory, and antiviral properties, to name a few. Moreover, Deacetyl ganoderic acid F exhibits effective outcomes for treating liver-associated diseases, for instance, hepatic fibrosis, liver cancer, and hepatitis, thereby, promising a potential therapeutic agent for liver dysfunctions. Group: Pharmaceutical. CAS No. 100665-44-9. Pack Sizes: 5 mg. Product ID: B0005-465655. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Deacetylpseudolaric acid A | Deacetylpseudolaric acid A isolated from the root bark of Pseudolarix amabilis. Group: Pharmaceutical. CAS No. 82508-37-0. Pack Sizes: 1 mg. Product ID: NP1452. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Deacetylpseudolaric acid C2 | Deacetylpseudolaric acid C2 isolated from the root bark of Pseudolarix amabilis. Uses: Demethoxydeacetoxypseudolaric acid b. Group: Pharmaceutical. CAS No. 82508-36-9. Pack Sizes: 1 mg. Product ID: NP1334. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Deacetylxylopic acid | Deacetylxylopic acid is isolated from the herbs of Nouelia insignis. Group: Pharmaceutical. CAS No. 6619-95-0. Pack Sizes: 5 mg. Product ID: NP1394. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 10-Deacetylbaccatin III | 10-Deacetylbaccatin-III is an antineoplastic agent and an anti-cancer intermediate. Group: Pharmaceutical. CAS No. 32981-86-5. Pack Sizes: 100 mg. Product ID: NP1767. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 10-Deacetylyunnanxane | 10-Deacetylyunnanxane is extracted from the roots of Taxus x media. Group: Pharmaceutical. CAS No. 1333323-17-3. Pack Sizes: 1 mg. Product ID: NP1369. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 19-Hydroxy-10-deacetyl baccatin-III | 19-Hydroxy-10-deacetylbaccatin III is an impurity of Baccatin III and is extracted from the needles of Taxus Baccata. It is used to synthesize 19-hydroxydocetaxel which is a compound that exhibits high level of cytotoxicity in vitro experimental models. Group: Pharmaceutical. CAS No. 154083-99-5. Pack Sizes: 5 mg. Product ID: B2694-468658. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 1-Deacetylnimbolinin B | 1-Deacetylnimbolinin B isolated from the seeds of Melia toosendan Sieb. et Zucc. Group: Pharmaceutical. CAS No. 76689-98-0. Pack Sizes: 5 mg. Product ID: NP6963. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 7,13-Dideacetyl-9,10-didebenzoyltaxchinin C | 7,13-Dideacetyl-9,10-didebenzoyltaxchinin C is extracted from the whole plants of Taxus chinensis var. mairei. Group: Pharmaceutical. CAS No. 156497-25-5. Pack Sizes: 1 mg. Product ID: NP1504. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 7-Xylosyl-10-deacetyltaxol B | 7-Xylosyl-10-deacetyltaxol B is extracted from the barks of Taxus wallichiana Zucc. Group: Pharmaceutical. CAS No. 90332-64-2. Pack Sizes: 5 mg. Product ID: NP1423. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 7-Xylosyl-10-deacetyltaxol C | 7-Xylosyl-10-deacetyltaxol C is extracted from the barks of Taxus wallichiana Zucc. Group: Pharmaceutical. CAS No. 90332-65-3. Pack Sizes: 50 mg. Product ID: NP1502. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 8-Deacetylyunaconitine | 8-Deacetylyunaconitine is an alkaloid isolated from the roots of Aconitum Vilmorinian Radix. Group: Pharmaceutical. CAS No. 93460-55-0. Pack Sizes: 1 mg. Product ID: NP0805. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 9-Deacetyl-9-benzoyl-10-debenzoyltaxchinin A | 9-Deacetyl-9-benzoyl-10-debenzoyltaxchinin A is extracted from the stem barks of Taxus baccata L. cv. stricta. Group: Pharmaceutical. CAS No. 172486-22-5. Pack Sizes: 1 mg. Product ID: NP1505. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Abexinostat | Abexinostat, also known as PCI-24781 or CRA-024781, is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity. Abexinostat inhibits several isoforms of HDAC, resulting in an accumulation of highly acetylated histones, followed by the induction of chromatin remodeling. Group: Pharmaceutical. CAS No. 783355-60-2. Pack Sizes: 100 mg. Product ID: B2693-286637. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Arg-Gly-Lys(Ac)-AMC | Ac-Arg-Gly-Lys(Ac)-AMC is a fluorogenic substrate for the determination of histone deacetylase (HDAC) activity in a two-step enzymatic reaction. Group: Pharmaceutical. CAS No. 660846-97-9. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015320. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Arg-Gly-Lys-AMC | Ac-Arg-Gly-Lys-AMC is a control for the two step histone deacetylase assay with Ac-Arg-Gly-Lys(Ac)-AMC. It corresponds to the product of the deacetylase reaction, which is subsequently cleaved by trypsin. Group: Pharmaceutical. CAS No. 660846-99-1. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015345. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Gly-Ala-Lys(Ac)-AMC | Ac-Gly-Ala-Lys(Ac)-AMC is a fluorogenic substrate used to measure histone deacetylase class I (HDAC 1, 2, 3 and 8) and class II (HDAC 6 and 10) activity in protease coupling assays. Ac-GAK-AM is formed from lysine deacetylation catalyzed by HDAC. Group: Pharmaceutical. CAS No. 577969-56-3. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015374. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Gly-Ala-Lys-AMC | Ac-Gly-Ala-Lys-AMC is the control peptide for protease-coupled histone deacetylase (HDAC) assay with Ac-Gly-Ala-Lys(Ac)-AMC. Group: Pharmaceutical. CAS No. 1926163-46-3. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-014588. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Lys-AMC | Ac-Lys-AMC, also known as MAL, is a fluorescent substrate for histone deacetylases (HDACs). Group: Pharmaceutical. CAS No. 156661-42-6. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015583. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Belinostat | Belinostat is a hydroxamic acid-type histone deacetylase (HDAC) inhibitor. Belinostat targets HDAC enzymes to inhibit tumor cell proliferation and angiogenesis, induce apoptosis and promote cellular differentiation. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 414864-00-9. Pack Sizes: 100 mg. Product ID: B0084-141764. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chitosan | Chitosan. CAS No. 9012-76-4. Categories: Poliglusam; Deacetylchitin; Poly-(D)glucosamine; BC; Chitopearl; Chitopharm; Flonac; Kytex. |  Cenik Chemicals |
| Chitosan | Chitosan is a deacetylated derivative of chitin. Chitosan is a polysaccharide present in the exoskeleton of a variety of crustaceans and cell walls of fungi. It can be used in the medical field and cosmetics manufacturing. In addition to its role in drug delivery, chitosan can also act as an adjuvant due to its immune-stimulating activity. Chitosan stimulates the immune system by activating the NLRP3 inflammasome, which produces potent IL-1b. When tested in an experimental model of vaccination, chitosan elicits a balanced Th1/Th2 response. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 9012-76-4. Pack Sizes: 1kg. Product ID: B1370-187887. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CXD101 | CXD101 is a selective histone deacetylase (HDAC) inhibitor with IC50 of 63 nM, 570 nM and 550 nM for HDAC1, HDAC2 and HDAC3, respectively. It exhibits antineoplastic activity. Group: Pharmaceutical. CAS No. 934828-12-3. Pack Sizes: 10 mg. Product ID: B1370-379907. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Entinostat | Entinostat is a histone deacetylase (HDAC) inhibitor displaying antiproliferative and antineoplastic effects. Entinostat induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), which slows cell growth, differentiation, and tumor development in vivo. Entinostat is potentially used as an antitumor drug in combination with other drugs like adriamycin, PARP inhibitors and Hsp90 inhibitors. Uses: Histone deacetylase inhibitors. Group: Pharmaceutical. CAS No. 209783-80-2. Pack Sizes: 500 mg. Product ID: B0084-062759. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Larotaxel | Larotaxel is a semi-synthetic derivative of the taxane 10-deacetylbaccatin III with potential antineoplastic activities. Larotaxel binds to tubulin, promoting microtubule assembly and stabilization and preventing microtubule depolymerization, thereby inhibiting cell proliferation. As it represents poor substrate for P-glycoprotein-related drug resistance mechanisms, this agent may be useful for treating multi-drug resistant tumors. Larotaxel penetrates the blood brain barrier. Group: Pharmaceutical. CAS No. 156294-36-9. Pack Sizes: 50 mg. Product ID: B2693-244933. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Panobinostat | Panobinostat is a cinnamic hydroxamic acid analogue with potential antineoplastic activity. Panobinostat selectively inhibits histone deacetylase (HDAC), inducing hyperacetylation of core histone proteins, which may result in modulation of cell cycle protein expression, cell cycle arrest in the G2/M phase and apoptosis. In addition, this agent appears to modulate the expression of angiogenesis-related genes, such as hypoxia-inducible factor-1alpha (HIF-1a) and vascular endothelial growth factor (VEGF), thus impairing endothelial cell chemotaxis and invasion. HDAC is an enzyme that deacetylates chromatin histone proteins. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 404950-80-7. Pack Sizes: 500 mg. Product ID: B0084-141578. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Pracinostat | Pracinostat (SB939) is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; the tumor suppressor protein-mediated inhibition of tumor cell division; and, finally, the induction of tumor cell apoptosis. This agent may possess improved metabolic, pharmacokinetic and pharmacological properties compared to other HDAC inhibitors. Group: Pharmaceutical. CAS No. 929016-96-6. Pack Sizes: 1 g. Product ID: B0084-286706. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rocilinostat | Rocilinostat is an orally bioavailable histone deacetylase 6 (HDAC6) inhibitor with potential antineoplastic activity. It selectively targets and binds to HDAC6, thereby disrupting the Hsp90 protein chaperone system through hyperacetylation of Hsp90 and preventing the subsequent aggresomal protein degradation. Compared to non-selective HDAC inhibitor, Rocilinostat is able to reduce the toxic effects on normal, healthy cells. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 1316214-52-4. Pack Sizes: 500 mg. Product ID: B0084-462644. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tucidinostat | Tucidinostat is a novel inhibitor of HDAC1, 2, 3, and 10 with IC50 values of 95, 160, 67, 78 nM, respectively. It increases the acetylation levels of histone H3 and decreases histone deacetylase (HDAC) activity, inducing apoptosis of cancer cells. Group: Pharmaceutical. CAS No. 1616493-44-7. Pack Sizes: 25 mg. Product ID: B2693-292408. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Vorinostat | Vorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC50 of ~10 nM. Uses: Antineoplastic agents; histone deacetylase inhibitors. Group: Pharmaceutical. CAS No. 149647-78-9. Pack Sizes: 5 g. Product ID: B2693-059322. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Vorinostat Impurities | Vorinostat Impurities, integral to pharmaceutical synthesis, undergo rigorous analysis to refine anti-cancer therapies. Specifically associated with the histone deacetylase inhibitor Vorinostat, they play a critical role in quality control, ensuring drug efficacy, particularly for cutaneous T-cell lymphoma, while providing key insights into Vorinostat's pharmacokinetics. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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