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| Product | Description | |
|---|---|---|
| Deacetylasperulosidic acid | Deacetylasperulosidic acid is a natural compound found in Morinda citrifolia fruit with antioxidant activity. Deacetylasperulosidic acid inhibited the reduction of ear swelling, and also cancelled the suppression of IL-2 production along with the activation of natural killer cells in the same manner as that of Noni-ext. Group: Pharmaceutical. Alternative Names: (1S,4aS,5S,7aS)-1-(β-D-Glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid. CAS No. 14259-55-3. Pack Sizes: 25 mg. Product ID: B1370-452428. Molecular formula: C16H22O11. Mole weight: 390.34. Custom synthesis is available. Send your inquiries for more information. |  London |
| Deacetyl ganoderic acid F | Deacetyl ganoderic acid F, a natural triterpenoid compound obtained from the Ganoderma lucidum, displays an array spectrum of pharmacological activities, particularly antitumor, immunomodulatory, and antiviral properties, to name a few. Moreover, Deacetyl ganoderic acid F exhibits effective outcomes for treating liver-associated diseases, for instance, hepatic fibrosis, liver cancer, and hepatitis, thereby, promising a potential therapeutic agent for liver dysfunctions. Group: Pharmaceutical. Alternative Names: Deacetyl ganoderic acid F; Ganoderic acid F, deacetyl-; (12beta)-12-Hydroxy-3,7,11,15,23-pentaoxolanost-8-en-26-oic acid. CAS No. 100665-44-9. Pack Sizes: 5 mg. Product ID: B0005-465655. Molecular formula: C30H40O8. Mole weight: 528.6. Custom synthesis is available. Send your inquiries for more information. | London |
| Deacetylpseudolaric acid A | Deacetylpseudolaric acid A isolated from the root bark of Pseudolarix amabilis. Group: Pharmaceutical. Alternative Names: (2E,4E)-5-[(1R,7S,8R,9R)-7-Hydroxy-4,9-dimethyl-11-oxo-10-oxatricyclo[6.3.2.01,7]tridec-3-en-9-yl]-2-methyl-2,4-pentadienoic acid. CAS No. 82508-37-0. Pack Sizes: 1 mg. Product ID: NP1452. Molecular formula: C20H26O5. Mole weight: 346.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Deacetylpseudolaric acid C2 | Deacetylpseudolaric acid C2 isolated from the root bark of Pseudolarix amabilis. Uses: Demethoxydeacetoxypseudolaric acid b. Group: Pharmaceutical. Alternative Names: (1R,7S,8R,9R)-9-[(1E,3E)-4-Carboxy-1,3-pentadien-1-yl]-7-hydroxy-9-methyl-11-oxo-10-oxatricyclo[6.3.2.01,7]tridec-3-ene-4-carboxylic acid. CAS No. 82508-36-9. Pack Sizes: 1 mg. Product ID: NP1334. Molecular formula: C20H24O7. Mole weight: 376.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Deacetylxylopic acid | Deacetylxylopic acid is isolated from the herbs of Nouelia insignis. Group: Pharmaceutical. Alternative Names: (5β,8α,9β,10α,13α,15β)-15-Hydroxykaur-16-en-18-oic acid. CAS No. 6619-95-0. Pack Sizes: 5 mg. Product ID: NP1394. Molecular formula: C20H30O3. Mole weight: 318.5. Custom synthesis is available. Send your inquiries for more information. | London |
| 10-Deacetylbaccatin III | 10-Deacetylbaccatin-III is an antineoplastic agent and an anti-cancer intermediate. Group: Pharmaceutical. Alternative Names: 10-Deacetylbaccatin (USP); 10-Deacetylbaccatin III; 10-desacetyl-baccatin III (EP); 5β,20-epoxy-4-(acetyloxy)-1,7β,10β,13α-tetrahydroxy-9-oxotax-11-en-2α-yl benzoate; Docetaxel EP Impurity E. CAS No. 32981-86-5. Pack Sizes: 100 mg. Product ID: NP1767. Molecular formula: C29H36O10. Mole weight: 544.59. Custom synthesis is available. Send your inquiries for more information. | London |
| 10-Deacetylyunnanxane | 10-Deacetylyunnanxane is extracted from the roots of Taxus x media. Group: Pharmaceutical. Alternative Names: 10-Deacetylyunnanxane; 1333323-17-3; [(1S,2S,3S,5S,8S,10S,14S)-2,5-diacetyloxy-10-hydroxy-8,12,15,15-tetramethyl-4-methylidene-14-tricyclo[9.3.1.03,8]pentadec-11-enyl] (2R,3S)-3-hydroxy-2-methylbutanoate. CAS No. 1333323-17-3. Pack Sizes: 1 mg. Product ID: NP1369. Molecular formula: C29H44O8. Mole weight: 520.66. Custom synthesis is available. Send your inquiries for more information. | London |
| 1-Deacetylnimbolinin B | 1-Deacetylnimbolinin B isolated from the seeds of Melia toosendan Sieb. et Zucc. Group: Pharmaceutical. Alternative Names: 1-Deacetylnimbolinin B; 76689-98-0; [(1R,2R,4R,6S,8R,11R,12S,13R,16R,17R,19S,20R)-17-acetyloxy-8-(furan-3-yl)-4,19-dihydroxy-1,9,11,16-tetramethyl-5,14-dioxapentacyclo[11.6.1.02,11.06,10.016,20]icos-9-en-12-yl] (E)-2-methylbut-2-enoate; C33H44O9; ZINC95910334. CAS No. 76689-98-0. Pack Sizes: 5 mg. Product ID: NP6963. Molecular formula: C33H44O9. Mole weight: 584.7. Custom synthesis is available. Send your inquiries for more information. | London |
| 7-Xylosyl-10-deacetyltaxol B | 7-Xylosyl-10-deacetyltaxol B is extracted from the barks of Taxus wallichiana Zucc. Group: Pharmaceutical. Alternative Names: Deacety-7-Xylosylcephalomannine, 10-(RG); 10-Deacetyl-7-xylosyltaxol B; 10-Deacetylcephalomannine 7-xyloside; 7-Xylosyl-10-deacetylcephalomannine. CAS No. 90332-64-2. Pack Sizes: 5 mg. Product ID: NP1423. Molecular formula: C48H59NO17. Mole weight: 921.97. Custom synthesis is available. Send your inquiries for more information. | London |
| 7-Xylosyl-10-deacetyltaxol C | 7-Xylosyl-10-deacetyltaxol C is extracted from the barks of Taxus wallichiana Zucc. Group: Pharmaceutical. Alternative Names: 10-Deacetyl-7-xylosylpaclitaxel; 10-Deacetyltaxol C 7-xyloside; 7-(beta-Xylosyl)-10-deacetyltaxol C; 10-Deacetyl-7-xylosyltaxol C. CAS No. 90332-65-3. Pack Sizes: 50 mg. Product ID: NP1502. Molecular formula: C49H63NO17. Mole weight: 938.03. Custom synthesis is available. Send your inquiries for more information. | London |
| 8-Deacetylyunaconitine | 8-Deacetylyunaconitine is an alkaloid isolated from the roots of Aconitum Vilmorinian Radix. Group: Pharmaceutical. Alternative Names: 8-Deacetylyunaconitine; 93460-55-0; CID 14139448; [11-ethyl-5,8,14-trihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] 4-methoxybenzoate. CAS No. 93460-55-0. Pack Sizes: 1 mg. Product ID: NP0805. Molecular formula: C33H47NO10. Mole weight: 617.736. Custom synthesis is available. Send your inquiries for more information. | London |
| 9-Deacetyl-9-benzoyl-10-debenzoyltaxchinin A | 9-Deacetyl-9-benzoyl-10-debenzoyltaxchinin A is extracted from the stem barks of Taxus baccata L. cv. stricta. Group: Pharmaceutical. Alternative Names: [(2S,4R,5R,5aS,6S,8S,9aR,10S,10aS)-6,10-diacetyloxy-2,4,8-trihydroxy-10a-(2-hydroxypropan-2-yl)-3,5a-dimethyl-9-methylidene-2,4,5,6,7,8,9a,10-octahydro-1H-benzo[g]azulen-5-yl] benzoate. CAS No. 172486-22-5. Pack Sizes: 1 mg. Product ID: NP1505. Molecular formula: C31H40O10. Mole weight: 572.65. Custom synthesis is available. Send your inquiries for more information. | London |
| Abexinostat | Abexinostat, also known as PCI-24781 or CRA-024781, is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity. Abexinostat inhibits several isoforms of HDAC, resulting in an accumulation of highly acetylated histones, followed by the induction of chromatin remodeling. Group: Pharmaceutical. Alternative Names: CRA-024781; CRA 024781; CRA024781; PCI-24781; PCI24781; PCI 24781. CAS No. 783355-60-2. Pack Sizes: 100 mg. Product ID: B2693-286637. Molecular formula: C21H23N3O5. Mole weight: 397.431. Custom synthesis is available. Send your inquiries for more information. | London |
| Alstolenine | Alstolenine is an alkaloid compound found in the Alstonia venenata. Group: Pharmaceutical. Alternative Names: Deacetylakuammiline trimethylgallate. CAS No. 85769-33-1. Pack Sizes: 1 mg. Product ID: NP0390. Molecular formula: C31H34N2O7. Mole weight: 546.6. Custom synthesis is available. Send your inquiries for more information. | London |
| Azadirachtin B | Azadirachtin B is a drug analog of azadirachtin which was investigated in agrochemical studies of bioregulators for the antifeedant mode of action of parent molecule against Lepidoptera and locusts. Group: Pharmaceutical. Alternative Names: Deacetylazadirachtinol; Azadirachtinol deacetyl; 3-tigloyl-azadirachtol; 3-Tigloylazadirachtol. CAS No. 106500-25-8. Pack Sizes: 10 mg. Product ID: B1370-382851. Molecular formula: C33H42O14. Mole weight: 662.68. Custom synthesis is available. Send your inquiries for more information. | London |
| Belinostat | Belinostat is a hydroxamic acid-type histone deacetylase (HDAC) inhibitor. Belinostat targets HDAC enzymes to inhibit tumor cell proliferation and angiogenesis, induce apoptosis and promote cellular differentiation. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: Belinostat; PXD 101; Beleodaq; PDX101; PX 105684; PXD-101; PXD101; (E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide. CAS No. 414864-00-9. Pack Sizes: 100 mg. Product ID: B0084-141764. Molecular formula: C15H14N2O4S. Mole weight: 318.347. Custom synthesis is available. Send your inquiries for more information. | London |
| Benzoylhypacoitine | Benzoylhypacoitine is extracted from the roots of Aconitum carmichaeli Debx. It might be the principal active components which affect mitochondrial growth by Fuzi and its processed products. Uses: Might be the principal active components which affect mitochondrial growth by fuzi and its processed products. Group: Pharmaceutical. Alternative Names: Benzoylhypaconine; Deacetylhypaconitine. CAS No. 63238-66-4. Pack Sizes: 20 mg. Product ID: B0005-464498. Molecular formula: C31H43NO9. Mole weight: 573.68. Custom synthesis is available. Send your inquiries for more information. | London |
| Ceftriaxone EP Impurity B | An impurity of Cefotaxime sodium. It is also a degradation product for other cephalosporin antibiotics such as: Ceftriaxone , Cefodizime and Ceftiofur. Group: Pharmaceutical. Alternative Names: [5aR-[5aα,6β(Z)]]-2-Amino-α-(methoxyimino)-N-(1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl)-4-thiazoleacetamide; 3-Desacetyl Cefotaxime Lactone; Deacetylcefotaxime lactone. CAS No. 66340-33-8. Pack Sizes: 10 mg. Product ID: B2694-468462. Molecular formula: C14H13N5O5S2. Mole weight: 395.42. Custom synthesis is available. Send your inquiries for more information. | London |
| Chitosan | Chitosan. CAS No. 9012-76-4. Categories: Poliglusam; Deacetylchitin; Poly-(D)glucosamine; BC; Chitopearl; Chitopharm; Flonac; Kytex. |  Cenik Chemicals |
| Chitosan | Chitosan is a deacetylated derivative of chitin. Chitosan is a polysaccharide present in the exoskeleton of a variety of crustaceans and cell walls of fungi. It can be used in the medical field and cosmetics manufacturing. In addition to its role in drug delivery, chitosan can also act as an adjuvant due to its immune-stimulating activity. Chitosan stimulates the immune system by activating the NLRP3 inflammasome, which produces potent IL-1b. When tested in an experimental model of vaccination, chitosan elicits a balanced Th1/Th2 response. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: Deacetylated chitin; Poly(D-glucosamine); Poly-b-(1,4)-2-Amino-2-deoxy-D-glucose; 2-Amino-2-deoxy-(1,4)-b-D-glucopyranan; deacetylchitin; b-1,4-poly-D-glucosamine; poly-D-glucosamine; poly-(1,4-b-D-glucopyranosamine). CAS No. 9012-76-4. Pack Sizes: 1kg. Product ID: B1370-187887. Molecular formula: [C7H15NO4]n. Mole weight: 60-120 kDa. Custom synthesis is available. Send your inquiries for more information. | London |
| Colchicine EP Impurity A | Colchicine EP Impurity A is a Colchicine derivative. It is a new alkaloid from Gloriosa superba. Group: Pharmaceutical. Alternative Names: N-Deacetyl-N-formyl Colchicine; Gloriosine; N-Formyldeacetylcolchicine; N-[(7S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]formamide. CAS No. 7411-12-3. Pack Sizes: 25 mg. Product ID: B1370-160311. Molecular formula: C21H23NO6. Mole weight: 385.41. Custom synthesis is available. Send your inquiries for more information. | London |
| CXD101 | CXD101 is a selective histone deacetylase (HDAC) inhibitor with IC50 of 63 nM, 570 nM and 550 nM for HDAC1, HDAC2 and HDAC3, respectively. It exhibits antineoplastic activity. Group: Pharmaceutical. Alternative Names: HDAC-IN-4; CXD-101; CXD 101; N-(2-Aminophenyl)-4-(1-((1,3-dimethyl-1H-pyrazol-4-yl)methyl)piperidin-4-yl)benzamide. CAS No. 934828-12-3. Pack Sizes: 10 mg. Product ID: B1370-379907. Molecular formula: C24H29N5O. Mole weight: 403.52. Custom synthesis is available. Send your inquiries for more information. | London |
| Desacetylcinobufagin | Botanical Source from Bufo bufo gargarizans and Bufo formosus, used for microbial transformation. Group: Pharmaceutical. Alternative Names: 3-beta,16-beta-Dihydroxy-14,15-beta-epoxy-5-beta-bufa-20,22-dienolide; Deacetylcinobufagin; Cinobufagin, deacetyl- (6CI). CAS No. 4026-95-3. Pack Sizes: 1 mg. Product ID: B2703-474160. Molecular formula: C24H32O5. Mole weight: 400.51. Custom synthesis is available. Send your inquiries for more information. | London |
| DM1-SMe | DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group. DM1-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC). Group: Pharmaceutical. Alternative Names: DM1-SMe; DM1-SSMe; maytansinoid derivative with ADC linker. Maytansine or mertansine or emtansine derivative; N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]maytansine. CAS No. 138148-68-2. Pack Sizes: 25 mg. Product ID: BADC-00020. Molecular formula: C36H50ClN3O10S2. Mole weight: 784.38. Custom synthesis is available. Send your inquiries for more information. | London |
| DM1-SPP | DM1 with a reactive linker SPP, which can react with antibody to make antibody drug conjugate, as a potent EGFR inhibitor and it overcomes resistant to EGFR. Group: Pharmaceutical. Alternative Names: N2'-deacetyl-N2'-[3-[[4-[(2,?5-dioxo-1-pyrrolidinyl)?oxy]?-1-methyl-4-oxobutyl]?dithio]?-1-oxopropyl]?-Maytansine; DM1 SPP. CAS No. 452072-20-7. Pack Sizes: 5 mg. Product ID: BADC-00010. Molecular formula: C44H59ClN4O14S2. Mole weight: 967.54. Custom synthesis is available. Send your inquiries for more information. | London |
| DM3 | DM3 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates. Group: Pharmaceutical. Alternative Names: N2'-deacetyl-N2'-(4-mercapto-1-oxopentyl)- maytansine. CAS No. 796073-54-6. Pack Sizes: 5 mg. Product ID: BADC-00339. Molecular formula: C37H52ClN3O10S. Mole weight: 766.34. Custom synthesis is available. Send your inquiries for more information. | London |
| DM3-SMe | DM3-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC). Group: Pharmaceutical. Alternative Names: N2'-deacetyl-N2'-[4-(R,S)-(methyldithio)-1-oxopentyl]maytansine. CAS No. 796073-70-6. Pack Sizes: 5 mg. Product ID: BADC-00022. Molecular formula: C38H54ClN3O10S2. Mole weight: 812.43. Custom synthesis is available. Send your inquiries for more information. | London |
| DM4 | DM4 is an anti-tubulin agent that inhibits cell division. DM4 can be used to prepare antibody-drug conjugates. DM4 binds to tubulin at the maytansine-binding site, disrupting microtubule assembly/disassembly dynamics and inhibiting mitosis. Group: Pharmaceutical. Alternative Names: Maytansinoid DM 4; Maytansine, N2'-deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-; N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-maytansine; Ravtansine. CAS No. 796073-69-3. Pack Sizes: 5 mg. Product ID: BBF-05778. Molecular formula: C38H54ClN3O10S. Mole weight: 780.37. Custom synthesis is available. Send your inquiries for more information. | London |
| DM4-SMe | DM4-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC). Group: Pharmaceutical. Alternative Names: N2'-deacetyl-N2'-[4-methyl-4-(methyldithio)-1-oxopentyl]maytansine. CAS No. 796073-68-2. Pack Sizes: 5 mg. Product ID: BADC-00021. Molecular formula: C39H56ClN3O10S2. Mole weight: 826.46. Custom synthesis is available. Send your inquiries for more information. | London |
| Docetaxel | Docetaxel, also called Taxoltere metro, a semisynthetic side-chain analogue of taxol differing at two positions in its chemical structure, is an inhibitior of microtubule disassembly (IC50 = 0.2 μM). And it inhibits cell replication (IC50 = 0.13 μM). Uses: Antitumor. Group: Pharmaceutical. Alternative Names: docetaxel; docetaxel anhydrous; docetaxel hydrate; docetaxel trihydrate; docetaxol; N-debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol; NSC 628503; RP 56976; RP-56976; Taxoltere metro; 114977-28-5. CAS No. 114977-28-5. Pack Sizes: 5 g. Product ID: NP3347. Molecular formula: C43H53NO14. Mole weight: 807.88. Custom synthesis is available. Send your inquiries for more information. | London |
| Entinostat | Entinostat is a histone deacetylase (HDAC) inhibitor displaying antiproliferative and antineoplastic effects. Entinostat induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), which slows cell growth, differentiation, and tumor development in vivo. Entinostat is potentially used as an antitumor drug in combination with other drugs like adriamycin, PARP inhibitors and Hsp90 inhibitors. Uses: Histone deacetylase inhibitors. Group: Pharmaceutical. Alternative Names: MS275; MS-275; MS 2275; SNDX275; SNDX-275; SNDX 275; Entinostat; pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate. CAS No. 209783-80-2. Pack Sizes: 500 mg. Product ID: B0084-062759. Molecular formula: C21H20N4O3. Mole weight: 376.416. Custom synthesis is available. Send your inquiries for more information. | London |
| Larotaxel | Larotaxel is a semi-synthetic derivative of the taxane 10-deacetylbaccatin III with potential antineoplastic activities. Larotaxel binds to tubulin, promoting microtubule assembly and stabilization and preventing microtubule depolymerization, thereby inhibiting cell proliferation. As it represents poor substrate for P-glycoprotein-related drug resistance mechanisms, this agent may be useful for treating multi-drug resistant tumors. Larotaxel penetrates the blood brain barrier. Group: Pharmaceutical. Alternative Names: XRP9881; PNU 100940. CAS No. 156294-36-9. Pack Sizes: 50 mg. Product ID: B2693-244933. Molecular formula: C45H53NO14. Mole weight: 831.912. Custom synthesis is available. Send your inquiries for more information. | London |
| M344 | M344 is a potent HDAC inhibitor, which can also induce expression of the pro-apoptotic genes, Puma and Bax, together with the morphological features of apoptosis, in MCF-7 cells. Group: Pharmaceutical. Alternative Names: M 344; M-344; Histone Deacetylase Inhibitor III. CAS No. 251456-60-7. Pack Sizes: 100 mg. Product ID: B1370-103604. Molecular formula: C16H25N3O3. Mole weight: 307.39. Custom synthesis is available. Send your inquiries for more information. | London |
| Mertansine | Mertansine, the cytotoxic component in antibody-drug conjugates, is attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker or SMCC (4-(3-mercapto-2,5-dioxo-1 pyrrolidinylmethyl)-cylohexanecarboxylic acid) linkerto create an antibody-drug conjugate. It derives from a maytansine. Group: Pharmaceutical. Alternative Names: (14S,16S,33S,2R,4R,10E,12Z,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-(3-mercaptopropanoyl)-N-methyl-L-alaninate; N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine; DM 1; Maytansinoid DM 1; N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine; DM-1; DM1; DM1 Compound; DM1 [Maytansinoid]. CAS No. 139504-50-0. Pack Sizes: 40 mg(95%+). Product ID: BBF-05777. Molecular formula: C35H48ClN3O10S. Mole weight: 738.29. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Acetyldelectine | N-Acetyldelectine is a norditerpenoid alkaloid isolated from the aerial parts of Delphinium formosum. Group: Pharmaceutical. Alternative Names: 14-Deacetylajadine; 14-Demethylajacine. CAS No. 63596-61-2. Pack Sizes: 1 mg. Product ID: NP0741. Molecular formula: C33H46N2O9. Mole weight: 614.736. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Me-L-Ala-maytansinol | N-Me-L-Ala-maytansinol is a hydrophobic, cell permeable payload used in the preparation of antibody-drug conjugate (ADC). Group: Pharmaceutical. Alternative Names: AP3 Intermidate 1; Maytansinol 3-(S)-α-N-methylaminopropionate; Maytansine, N2'-deacetyl-; (1S,2R,3S,5S,6S,16Z,18Z,20R,21S)-11-Chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10(26),11,13,16,18-pentaen-6-yl N-methyl-L-alaninate; Maytansinol-Ala. CAS No. 77668-69-0. Pack Sizes: 500 mg. Product ID: BBF-05880. Molecular formula: C32H44ClN3O9. Mole weight: 650.17. Custom synthesis is available. Send your inquiries for more information. | London |
| Paclitaxel EP Impurity G | Paclitaxel EP Impurity G is an impurity of Paclitaxel, which is a mitotic inhibitor used in cancer chemotherapy. Group: Pharmaceutical. Alternative Names: 4-(Acetyloxy)-13α-[[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy]-1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-en-2α-yl benzoate; 10-O-Deacetylpaclitaxel; Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-; Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-; 10-Deacetylpaclitaxel; 10-Deacetyltaxol; 10-Deacetyltaxol A; 10-Desacetylpaclitaxel; 10-Desacetyltaxol; 10-O-Deacetyltaxol; Paclitaxel impurity G; (2aR,4S,4aS,6R,9S,11S,12S,12bS)-12b-Acetoxy-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate. CAS No. 78432-77-6. Pack Si | London |
| Paclitaxel EP Impurity H | Paclitaxel EP Impurity H is an impurity of Paclitaxel, which is a mitotic inhibitor used in cancer chemotherapy. Group: Pharmaceutical. Alternative Names: 4-(Acetyloxy)-13α-[[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy]-1,7α,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-en-2α-yl benzoate; 10-O-Deacetyl-7-epi-paclitaxel; 7-Epi-10-deacetyltaxol; Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-; 10-Deacetyl-7-epi-paclitaxel; 10-Deacetyl-7-epi-taxol; 10-Deacetyl-7-epipaclitaxel; 10-Deacetyl-7-epitaxol; 10-Desacetyl-7-epipaclitaxel; 7-epi-10-Deacetylpaclitaxel; Ormosin VI; USP Paclitaxel Related Compound B; Paclitaxel USP Related Compound B; Paclitaxel Related Compound B. CAS No. 78454-17-8. Pack Sizes: 25 mg. Product ID: NP1519. Molecular formula: C45H49NO13. Mole weight: 811.88. Custom synthesis is available. Send your inquiries for more information. | London |
| Paclitaxel EP Impurity J | Paclitaxel EP Impurity J is an impurity of Paclitaxel, which is a mitotic inhibitor used in cancer chemotherapy. Group: Pharmaceutical. Alternative Names: 4-(Acetyloxy)-13α-[[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy]-1,7β-dihydroxy-9-oxo-10β-[(3-oxobutanoyl)oxy]-5β,20-epoxytax-11-en-2α-yl benzoate; 10-O-Deacetyl-10-O-(3-oxobutanoyl)paclitaxel; 10-Acetoacetyl Paclitaxel; 10-Acetoacetyl Abraxane; 10-Acetoacetyl Genaxol; 10-Acetoacetyl Genetaxyl; 10-Acetoacetyl Onxal; 10-Acetoacetyl Pacliex; 10-Acetoacetyl (-)-Paclitaxel; 10-Acetoacetyl Taxo. CAS No. 2757197-26-3. Pack Sizes: 10 mg. Product ID: B1370-247559. Molecular formula: C49H53NO15. Mole weight: 895.94. Custom synthesis is available. Send your inquiries for more information. | London |
| Panobinostat | Panobinostat is a cinnamic hydroxamic acid analogue with potential antineoplastic activity. Panobinostat selectively inhibits histone deacetylase (HDAC), inducing hyperacetylation of core histone proteins, which may result in modulation of cell cycle protein expression, cell cycle arrest in the G2/M phase and apoptosis. In addition, this agent appears to modulate the expression of angiogenesis-related genes, such as hypoxia-inducible factor-1alpha (HIF-1a) and vascular endothelial growth factor (VEGF), thus impairing endothelial cell chemotaxis and invasion. HDAC is an enzyme that deacetylates chromatin histone proteins. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: LBH589; LBH 589; LBH-589; NVP-LBH589; NVP-LBH 589; Panobinostat; trade name Farydak. CAS No. 404950-80-7. Pack Sizes: 500 mg. Product ID: B0084-141578. Molecular formula: C21H23N3O2. Mole weight: 349.434. Custom synthesis is available. Send your inquiries for more information. | London |
| Pracinostat | Pracinostat (SB939) is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; the tumor suppressor protein-mediated inhibition of tumor cell division; and, finally, the induction of tumor cell apoptosis. This agent may possess improved metabolic, pharmacokinetic and pharmacological properties compared to other HDAC inhibitors. Group: Pharmaceutical. Alternative Names: SB939; SB 939; SB-939; SC-939; SC 939; SC939; Pracinostat. CAS No. 929016-96-6. Pack Sizes: 1 g. Product ID: B0084-286706. Molecular formula: C20H30N4O2. Mole weight: 358.486. Custom synthesis is available. Send your inquiries for more information. | London |
| Pseudolaric Acid C | Pseudolaric Acid C usually can be isolated from the root bark of Pseudolarix amabilis. Group: Pharmaceutical. Alternative Names: (3R,4R,4aS,9aR)-rel-3-[(1E,3E)-4-Carboxy-1,3-pentadienyl]-3,4,4a,5,6,9-hexahydro-4a-hydroxy-3-methyl-1-oxo-1H-4,9a-ethanocyclohepta[c]pyran-7-carboxylic acid 7-methyl ester; Deacetylpseudolaric acid B. CAS No. 82601-41-0. Pack Sizes: 10 mg. Product ID: B2703-286632. Molecular formula: C21H26O7. Mole weight: 390.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Rocilinostat | Rocilinostat is an orally bioavailable histone deacetylase 6 (HDAC6) inhibitor with potential antineoplastic activity. It selectively targets and binds to HDAC6, thereby disrupting the Hsp90 protein chaperone system through hyperacetylation of Hsp90 and preventing the subsequent aggresomal protein degradation. Compared to non-selective HDAC inhibitor, Rocilinostat is able to reduce the toxic effects on normal, healthy cells. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: ACY-1215; ACY1215; ACY 1215; Rocilinostat; 2-(Diphenylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide. CAS No. 1316214-52-4. Pack Sizes: 500 mg. Product ID: B0084-462644. Molecular formula: C24H27N5O3. Mole weight: 433.512. Custom synthesis is available. Send your inquiries for more information. | London |
| Toosendanin | Toosendanin is a natural diterpenoid compound found in the barks of Melia toosendan Sieb. et Zucc. Toosendanin shows hepatotoxicity and is also an effective insecticide for Ae. Group: Pharmaceutical. Alternative Names: 24-Norchola-20,22-diene-4-carboxaldehyde,3,12-bis(acetyloxy)-14,15:21,23-diepoxy-1,7,19-trihydroxy-4,8-dimethyl-11-oxo-,cyclic4,19-hemiacetal, [C(R),1α,3α,4β, 5α,7α,12α,13α,14β,15β,17α]-;Chuanliansu;28-Deacetylsendanin;12-AcetoxyaMoorastatin. CAS No. 58812-37-6. Pack Sizes: 20 mg. Product ID: NP6990. Molecular formula: C30H38O11. Mole weight: 574.62. Custom synthesis is available. Send your inquiries for more information. | London |
| Tucidinostat | Tucidinostat is a novel inhibitor of HDAC1, 2, 3, and 10 with IC50 values of 95, 160, 67, 78 nM, respectively. It increases the acetylation levels of histone H3 and decreases histone deacetylase (HDAC) activity, inducing apoptosis of cancer cells. Group: Pharmaceutical. Alternative Names: HBI-8000; CS-055; Chidamide; Epidaza. CAS No. 1616493-44-7. Pack Sizes: 25 mg. Product ID: B2693-292408. Molecular formula: C22H19FN4O2. Mole weight: 390.41. Custom synthesis is available. Send your inquiries for more information. | London |
| Vorinostat | Vorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC50 of ~10 nM. Uses: Antineoplastic agents; histone deacetylase inhibitors. Group: Pharmaceutical. Alternative Names: MK-0683, MK 0683, MK0683, SAHA, M344, CCRIS 8456, HSDB 7930, Vorinostat, suberoylanilide hydroxamic acid, Zolinza. CAS No. 149647-78-9. Pack Sizes: 5 g. Product ID: B2693-059322. Molecular formula: C14H20N2O3. Mole weight: 264.3. Custom synthesis is available. Send your inquiries for more information. | London |
| Wilfortrine | Wilfortrine is a natural compound of the sesquiterpenoid class found in the roots of Tripterygium wilfordii Hook. f. Wilfortrine exhibits an inhibitory effect on liver cancer cell proliferation. Group: Pharmaceutical. Alternative Names: Evonimine, 8-(acetyloxy)-O(sup 2)-deacetyl-8-deoxo-O(sup 2)-(3-furanylcarbonyl)-26-hydroxy-, (8-alpha)-. CAS No. 37239-48-8. Pack Sizes: 5 mg. Product ID: B0005-465902. Molecular formula: C41H47NO20. Mole weight: 873.814. Custom synthesis is available. Send your inquiries for more information. | London |
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